Acidithiobacillus thiooxidans: GCD22_03070
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Entry
GCD22_03070 CDS
T06281
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
atx
Acidithiobacillus thiooxidans
Pathway
atx00230
Purine metabolism
atx01100
Metabolic pathways
atx01110
Biosynthesis of secondary metabolites
Module
atx_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
atx00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
GCD22_03070 (purL)
Enzymes [BR:
atx01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
GCD22_03070 (purL)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
QFX97182
UniProt:
A0A5P9XTQ1
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All DBs
Position
complement(2735144..2739004)
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AA seq
1286 aa
AA seq
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MLLLRGSAALSAFRLQHLLKLLQEADLPVAYLNARFVHLLDLSEALNAEQTGVVTALLHY
GTPFTEESQDGIQEICVLPRLGTISPWSSKASEIFRHCGLGNVRRVERGVSYTLMRAGVG
IFSTTEMEQIRRQLHDPMTESVLSDWYAAEAIFKHPEPAHLRRVALQAEGMTALTEANRS
MGLALSPAELDYLKDYFSDLGRDPSDAELMMFAQANSEHCRHKVFNAHYHLDGENQSQSL
FGMIRETHRLNPQGTLSAYKDNAAVMASIMTSQPFAVAADGQYRPTEENTAILMKVETHN
HPTAISPFPGAATGSGGEIRDEGATGRGGKPKAGLTGFSVSHLRIPGYTQSWEQPFYGKP
ARIRSALEIMRGGPLGAAAFNNEFGRPAIAGYFRVFECDHDGVHRGYHKPIMLAGGLGQI
RPQMVEKQPLPIGAKVLVIGGPAMLIGLGGGAASSVASGSGDEQLDFASVQRGNPEMQRR
AQEVIERCVALGQDSPILSIHDVGAGGLSNAVPELLHDGGRGGRLQLRTIPNEEPAMSPM
QIWSNEAQERYVLAVTPEDLPRFEAICQRERCPYAVLGEAVEEDVLLVEDALLQDTPVDM
ALSALLGCPPRMERNSRHQMVQTQSLDLSGTVLRDAAYAVLRHPSVASKEFLITIGDRSV
GGLIHRDQMVGPWQVPVADCGVTAADFWNTHGEAMAIGERAPVAVLNPVASARLAIAEAL
TNLWAADVRVLDNIKLSANWMAAVDHPGEDAALFDAVKAAALEVCPALDLAIPVGKDSLS
MRTLWQEEGQDKAVVSPLSLIITAFTPVQDLRKTWTPQWAAQEETDLWLVDLGQGRLGAS
ILAQTVGQMGAETPDMDQPELLRKLFAALCSLREQELVLAYHDRADGGLWATLCEMSFAS
RCGADMVLPAGADVWSFLFAEEPGVLLQVAAKDRETVRGIFAEKDLDTRAQCLGTVHVGH
WQLRVLQGEQVLLNEPIAELLQAWTENSYQMASLRDDPQCAKEAFAAATAMEAPLFSRVP
FSPQMPMIQQGVQPKVAILREQGVNGQVEMAAAFHRAGFTAVDVHMSDLTSGRYRLNDFQ
ALAACGGFSYGDVLGAGAGWAKSILFHSALLDQFAAFFADESRLALGVCNGCQMMAELRE
IIPGAGHWPLFTRNRSEQFEARLAMVEVLDSPSLWFSGMAGTYAPIVIAHGEGRAHFDST
TEGSPAPVTMRYVDAMGQVARHYPANPNGSPEGITGLCNEDGRVAILMPHPERVVRSLQM
SWAPADWGELTPWMQIFTNARKVLGS
NT seq
3861 nt
NT seq
+upstream
nt +downstream
nt
atgctgctgctgcgcggctctgcggccctttctgcctttcgtctgcaacatctgctgaaa
ctcctgcaagaagcggaccttccggttgcttatctgaatgcgcgctttgtgcatctgctt
gacctgagtgaagccctcaacgccgaacaaactggtgtggtcaccgctctgctgcactat
ggaacgccatttaccgaagagtcccaggatggaattcaggaaatttgcgtgttgccgcgc
ctgggtaccatttctccctggtcgagcaaagccagcgaaattttccggcattgcgggctt
ggcaacgtccgcagggtcgagcgcggtgtgtcctatacgctgatgcgtgccggagtgggt
attttcagcacgacagaaatggagcaaatccgtcggcagcttcatgatcccatgaccgaa
tctgtgctttctgactggtatgcagccgaggccattttcaagcaccccgagccggcacat
ttgcggcgggtggcgctgcaggcagagggcatgacggccttgactgaagccaatcgcagc
atgggactggcgttgtctcctgctgaactggattacctgaaggattatttttcagatttg
ggccgagatcccagtgatgccgaactgatgatgtttgcccaggcgaattccgagcattgt
cgccataaggtatttaacgcccactaccatctggatggcgaaaatcagtcccagagtctg
tttggcatgatccgtgaaacccatcgcctgaatccgcaaggcactttatctgcctacaag
gacaacgcagcagtcatggcgagtatcatgaccagtcagccctttgccgtggctgccgac
ggtcagtatcggccaacggaagaaaacaccgccattttgatgaaggtggaaacccacaat
catccaacggccatttctccctttccgggcgcggccacgggcagtggtggggaaattcgg
gatgaaggggccacggggcggggcggcaaacccaaggcgggtctgaccgggttctcggta
tctcatctgcgtattccgggttatacccagtcctgggaacagcctttttatggaaagccg
gcgcggattcgttccgctctggaaatcatgcgcggtggaccgctgggtgcggctgctttc
aacaatgaatttggacgtccggccattgccggttatttccgggtttttgagtgtgatcac
gatggggtgcatcgcggttaccacaagcccatcatgctggccggagggttggggcaaatc
cgcccgcagatggtggaaaaacagcctttgccgatcggcgcgaaagtgttggtgattggt
ggtccggctatgctcatcggtctgggtggcggtgccgcttccagtgtggccagcggatcg
ggcgatgaacaactggattttgcctcggtgcaacggggtaatcctgaaatgcaacggcgg
gcccaggaagtgattgaacgctgcgtggctttgggccaggattcccccatcctctccatt
catgatgtgggtgccggtggattatccaacgccgttcccgagttattacatgatgggggt
cggggcgggcgcttgcagttgcgcacgatacctaatgaagaacccgccatgtcgcccatg
caaatctggagtaatgaagcgcaggagcgctatgtgttggcggttactccagaggatttg
ccgcgctttgaggccatttgtcagcgtgagcgttgcccctacgccgtactgggtgaggct
gtggaagaagatgtccttctggtcgaagatgcgctcctgcaggatactcctgtagatatg
gcactcagcgcgctactgggttgtccgccgcgcatggaaagaaatagccggcatcaaatg
gttcagacccaatctctggacctgtctggaacggttttgcgcgatgctgcctatgcggtg
ctccgtcatccctcggtagccagtaaggagtttctgattaccattggcgaccggagcgtg
gggggcctgattcaccgcgatcagatggtcggtccctggcaggtgccggttgctgactgt
ggagtgactgcagcagatttctggaatacccacggtgaggcgatggccattggcgaaagg
gcgccagtggcagttctgaaccctgtggccagcgcgcgcctggccattgctgaagcactg
accaatctctgggcggcagatgtgcgggtactggataacatcaagctctcggccaactgg
atggcggcagtggatcatcccggcgaagatgcagctctctttgatgccgtcaaggcagca
gccctggaagtttgtcctgccctggatctggccattccggtgggaaaagactccttgtcc
atgcgcacgctctggcaggaagaagggcaggacaaagcggtcgtctctcctctttccctg
attattacggcttttacgcccgtgcaggatctgcgcaagacctggacgccccagtgggcg
gcccaggaagagacggatttatggctggttgatttaggacagggccgtctgggggcttct
atcctcgcccagacagtggggcaaatgggcgcggaaacgccggacatggatcagcctgaa
ctgttgcgtaaactttttgcggcgctatgcagcttgcgtgaacaggaactcgtgctcgcc
tatcatgaccgtgccgatggcgggctgtgggctacgctgtgtgaaatgtcatttgcgagt
cgttgcggagcggatatggtgctgcctgccggggccgatgtctggtctttcctgtttgcg
gaggagccgggcgtattgcttcaggtagcggccaaagatcgggaaaccgtgcggggcatt
tttgcggaaaaggatctggacacccgggctcagtgccttggtaccgtgcatgtcgggcat
tggcagctgcgggtactgcagggtgaacaggtattactgaacgaacccattgcggagttg
ctgcaggcatggactgaaaacagctatcagatggcgtcgttgcgtgacgatccgcaatgc
gccaaagaagcatttgctgccgcgaccgcaatggaagctccgcttttctcccgtgttccc
ttcagtccgcagatgcccatgattcagcagggtgtgcagcccaaagtggccattttgcgt
gagcagggcgtcaatggtcaggttgaaatggcggctgcttttcaccgtgccggattcacg
gctgtggatgtccacatgagtgatctgactagtggacgttatcgcctcaatgattttcag
gcattggcagcttgtggcggcttttcttatggcgatgtgctgggtgccggggctggttgg
gccaagtccattctgtttcattcggcattgctggaccagtttgcggcgttttttgcagat
gaatcgcgcctggccctgggtgtctgcaatggctgccagatgatggctgaattgcgggaa
atcattcccggagccgggcattggccattatttacccgcaatcgttctgagcaatttgaa
gcccgcctggccatggtggaagtgctggactctccttccctgtggtttagcgggatggcc
ggaacctatgcaccgattgtcatcgcccatggcgaaggccgtgcccactttgacagtacc
accgaagggtctcctgcaccggtcaccatgcgttacgtggacgccatggggcaagtggca
cgtcactatccggccaaccccaacggatcgccggaagggatcaccgggctctgcaatgaa
gatggtcgggttgccattttgatgccgcatcccgagcgggtcgtgcgtagcctgcaaatg
agctgggcaccagcagattggggcgaattgacgccgtggatgcagatattcaccaatgcc
cgcaaagtgctgggatcctga
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