Actinomyces viscosus: NCTC10951_01085
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Entry
NCTC10951_01085 CDS
T06789
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
avc
Actinomyces viscosus
Pathway
avc00300
Lysine biosynthesis
avc00550
Peptidoglycan biosynthesis
avc01100
Metabolic pathways
avc01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
avc00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NCTC10951_01085 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NCTC10951_01085 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NCTC10951_01085 (murF)
Enzymes [BR:
avc01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
NCTC10951_01085 (murF)
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
VEI15291
UniProt:
A0A3S4WJ64
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All DBs
Position
1:complement(1220844..1222307)
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AA seq
487 aa
AA seq
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MGTGMNLSLSQIAAAVGGRLIGPDASVTGPVVTDSRQAAEGALFVAVHGERTDGHAHLGS
ALRLGAVGAIVSDLEAARAGLSGEEIEAAPEDLPMGLVLVEDTVTALGALARTHLAGLRR
AAEDRGQRLTVVAMTGSVGKTTTKDLTRQLLAASGPTVAPRASFNNEIGLPLTVLEADER
TRYLVLEMGASGPGHIAYLTDIAPLDAAGVLMIGHAHMGGFGSIEGVAAAKAEIIAGLLP
GGTTILNADDARAAAMAQLAPARVLTFSSHGAPADLRAERIVLDAAARAAFDLHLPGLDG
PRRVQLAVAGAHNVANALAAAGLALAAGLAPELIAERLGSVSIESPHRMDVSELSGDLLL
IDDSYNANIDSMTAALAALPALAGDRRRVVVVSEMLELGESSAADHARTGELVAQAGAAM
LIGIGSTQEALEAAGARGVEVVGFDDAATAISQIDALLSDGDAVLVKGSNGSGAWRLADH
LKEVRPR
NT seq
1464 nt
NT seq
+upstream
nt +downstream
nt
atggggacggggatgaatctcagcctgagtcagatcgcggccgccgtcggcggcagactc
atcggcccggacgcctccgtcaccggccccgtcgtcaccgactcccgtcaggccgccgag
ggtgccctgttcgtcgccgtccacggcgagcgcaccgacggccacgcccacctgggctcc
gcgctccgtctgggcgccgtcggggccatcgtctccgacctggaggccgcccgagccggg
ctgtccggggaggagatcgaggcggcccccgaggacctgcccatgggactcgtcctcgtg
gaggacaccgtcaccgccctgggcgccctggcccgcacccacctggccggtctgcgccgg
gccgcggaggatcgcgggcagcggctcaccgtcgtcgcgatgaccggctcggtgggtaag
accaccacgaaggacctcacccgccagctgctggccgcctccggcccgacggtggcgccc
agagccagcttcaacaacgagatcggcctgccgctgaccgtcctggaggccgacgagcgc
acccgctacctcgtcctggagatgggagcctccggtcccggccacatcgcctacctcacc
gacatcgcgccgctggacgcggccggggtcctcatgatcggccacgcccacatgggcggg
ttcggctccatcgagggggtcgccgccgccaaggcggagatcatcgccggcctgctgccc
ggcggcaccaccatcctcaacgccgacgacgcccgcgccgccgccatggcgcagctcgcc
ccggcacgggtcctcaccttctccagccacggagccccggcggacctgcgcgccgagcgc
atcgtcctggatgcggcggcccgcgcggccttcgacctccacctgcccggactcgacggg
ccccggcgcgtccagctggccgtggccggtgcccacaacgtggccaacgccctggccgcc
gcgggcctggccctggccgcggggctggcacccgagctcatcgccgagcggctcggatcc
gtgagcatcgagagcccccaccgcatggatgtgtccgagctcagtggtgatcttcttctt
atcgacgactcctacaacgccaacatcgactccatgacggcggcgctggccgctctgccg
gccctggccggggacaggcgccgcgtcgtcgtggtttccgagatgctcgagctgggggag
tcctccgccgccgatcatgcgcgcaccggggagctagtggctcaggccggagccgctatg
ctcatcggcatcggctccacccaggaggcactcgaggcagccggggcgcgaggggtcgag
gtcgtcggcttcgatgatgccgcgaccgccatctcccagatcgacgccctcctgtccgac
ggtgatgccgtcctggtcaagggctccaacggatcaggcgcctggcgcctggccgaccac
ctcaaggaggttcgtccccgatga
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