KEGG   Actinomyces weissii: JG540_08070
Entry
JG540_08070       CDS       T07198                                 
Name
(GenBank) bifunctional dTDP-4-dehydrorhamnose 3,5-epimerase family protein/NAD(P)-dependent oxidoreductase
  KO
K23987  dTDP-4-dehydrorhamnose 3,5-epimerase/reductase [EC:5.1.3.13 1.1.1.133]
Organism
awe  Actinomyces weissii
Pathway
awe00521  Streptomycin biosynthesis
awe00523  Polyketide sugar unit biosynthesis
awe00541  Biosynthesis of various nucleotide sugars
awe01100  Metabolic pathways
awe01110  Biosynthesis of secondary metabolites
awe01250  Biosynthesis of nucleotide sugars
Module
awe_M00793  dTDP-L-Rha biosynthesis, Glc-1P => dTDP-L-Rha
Brite
KEGG Orthology (KO) [BR:awe00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00541 Biosynthesis of various nucleotide sugars
    JG540_08070
  09109 Metabolism of terpenoids and polyketides
   00523 Polyketide sugar unit biosynthesis
    JG540_08070
  09110 Biosynthesis of other secondary metabolites
   00521 Streptomycin biosynthesis
    JG540_08070
Enzymes [BR:awe01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.133  dTDP-4-dehydrorhamnose reductase
     JG540_08070
 5. Isomerases
  5.1  Racemases and epimerases
   5.1.3  Acting on carbohydrates and derivatives
    5.1.3.13  dTDP-4-dehydrorhamnose 3,5-epimerase
     JG540_08070
SSDB
Motif
Pfam: RmlD_sub_bind dTDP_sugar_isom Epimerase GDP_Man_Dehyd NAD_binding_4 adh_short NAD_binding_10
Other DBs
NCBI-ProteinID: QQM66996
UniProt: A0A7T7M8R8
LinkDB
Position
1993408..1994838
AA seq 476 aa
MTMTPKPLRIETTPIPGFLRIDLTVHGDNRGWFKENWQREKMLALGLPDFGPVQNNISFN
DEVGVTRGIHAEPWDKFVSVATGRVFGAWVDLREGPTFGTVYTCEIDPSVAVYVPKGVGN
AYQTLEPNTAYTYLVNDHWSPEARYTFLNLADETVAVPWPIPLEQAILSDKDKAHPRLEQ
VTPFPALPARGRRVLVTGAKGQLGRELMRQLPAAGFTATGVDLPDFDISDPATVQAVDWS
AYDVVVNAAGWTDVDGAQSAAGRSQAWQANATGPAHLARAASRHGLTLVHVSSEYVFDGS
AETHLEDEAPSPLGVYGQSKAGGDAAAAACPTHYLVRTSWVVGEGRNFVRTMAELARRGT
KPQVVCDQVGRLTFTKDLAAGIIHLLSTQAPYGTYNLSGTGPAASWYEVARLVYQLTGHN
PQDVSPVTTAEYYAGHEGISPRPAHSTLDLSKLTATGFTPESWTEGLERYLGEQQV
NT seq 1431 nt   +upstreamnt  +downstreamnt
atgaccatgacccccaagcccctgaggatcgagaccacgcccatccctggcttcctgcgt
atcgacctgactgtccacggggacaaccggggctggttcaaggagaactggcagcgcgag
aagatgctggcgctcggcctgccggacttcgggccggtccagaacaacatctccttcaac
gacgaggtgggcgtgacccgcggcatccacgccgagccctgggacaagttcgtctccgtg
gccaccggccgtgtgttcggcgcctgggtggacctgcgtgagggccctaccttcggtacg
gtctacacctgtgagatcgacccctcagtggccgtgtacgtgcccaagggcgtgggcaac
gcctaccagaccctggagcccaacactgcctacacctacctggtgaacgaccactggtcc
cccgaggcccggtacaccttcctgaacctggctgacgagacggtggccgtgccctggccc
atccccctggagcaggcgatcctctctgacaaggacaaggcccacccgcgcctggagcag
gtcacgcccttccccgccctgcccgcccggggacgccgcgtgctggtcacgggggccaag
ggccagctgggccgcgagctgatgcgccagctgcccgccgccgggttcacggccaccggc
gtggacctgcccgacttcgacatctccgaccccgccaccgtgcaggcggttgactggtct
gcctacgacgtcgtggtcaacgcggctggctggaccgacgtcgacggggcgcagagcgca
gccggacgtagccaggcatggcaggccaacgccaccggcccggcccacctggcccgcgcc
gccagcaggcacggcctgaccctggtgcacgtctccagcgagtacgtctttgacggcagc
gccgagacccatctggaggacgaggcccccagcccgctgggcgtctacgggcagtcgaag
gccgggggcgacgccgctgccgccgcctgccccacgcactacctggtgcgtaccagctgg
gtcgtgggcgagggccgcaacttcgtgcggaccatggccgagctggcccggcggggcacc
aagccgcaggtagtctgcgaccaggttgggcgcctgaccttcaccaaggacctggctgca
ggcatcatccacctgctgtccacgcaggccccctacggcacctacaacctctctggcacg
ggcccggccgcctcctggtacgaggttgccaggctggtctaccagctcaccgggcacaac
ccgcaggacgtctcccctgtgaccaccgcggagtactacgcaggccatgagggtatctcc
ccccgcccagcccacagcaccctggacctgagcaagctgacggccacgggcttcaccccc
gagagctggaccgagggcctggagcggtacctgggcgagcagcaggtctga

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