Acetobacterium wieringae: CHL1_000458
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Entry
CHL1_000458 CDS
T08273
Symbol
hemC
Name
(GenBank) hydroxymethylbilane synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
awi
Acetobacterium wieringae
Pathway
awi00860
Porphyrin metabolism
awi01100
Metabolic pathways
awi01110
Biosynthesis of secondary metabolites
awi01120
Microbial metabolism in diverse environments
awi01240
Biosynthesis of cofactors
Module
awi_M00924
Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide
Brite
KEGG Orthology (KO) [BR:
awi00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
CHL1_000458 (hemC)
Enzymes [BR:
awi01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
CHL1_000458 (hemC)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
CHL1_000458 (hemC)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Porphobil_deam
HEM4
TP_methylase
Porphobil_deamC
Motif
Other DBs
NCBI-ProteinID:
URN84870
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Position
478097..480514
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AA seq
805 aa
AA seq
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MNIKVGTRGSTLARTQSQWLIDVLAKTHPQVNFEMVIIKTKGDLVQDKPLDKIGDKGLFT
KELEDALLSGEIDMAIHSMKDMPSKLPEGLVLTVPPVREDARDVLLTPHRITALDELPKG
AVVATGSKRRIAQLQKLRPDVEIVGIRGNIDTRIRKMQEQQLDGIILAAAGLKRIGRLED
SAYYTVALPETTFIPAPAQGILAVEVREDNQTVNELMAVISDQNTIVQMSAERSFLNALN
GSCHIPVGAFCEIEAEEITVYGLYGLEDGSRVVTRSIKGAPEEAENLGKQLAKACYQAVH
EKPGKVYLAGGGCGDPGLLTVKAKDILTKADVVVYDALVNESFLNDARADAEIIYVGKRA
GNHAMRQEDINALLVQKGQEGKLVLRLKGGDPYVFGRGGEEGEDLYDAGVPFEVIPGITS
VIGGLAYAGIPITHRDCVSSFHVITGHLKSNAYDGSSDLDWPVLGKLKGTIVFLMGVKNL
EKICDELVKNGMNPEMPVAVVHRASTPYQRVVTGNLTTIYDIAAEAKITAPSLIVVGEVV
NKRQKLRFFDEKPLFGKNIIVTRSREQSSQMVEKITELGGNAIEFPTIKIVPINEAACDE
KVKCLKDYSHIIFTSINGVEVFFDSLARCGKDARAFGNLHITAIGEGTKNALLARGLQAD
FVPDKYVGEELVSGLVPLLTKDSRVLIPRSKNARIYVVQELSKICPVDEVQSYETIREDH
ATIDPLAMLTNKEIDYITFTSSTTVEFFVEKIGAAHIDAINTAKCVSIGPQTSKKCVELG
ITVDIEAETYTIQGMLDAILKDSQK
NT seq
2418 nt
NT seq
+upstream
nt +downstream
nt
atgaatataaaagttggaacacggggcagcacgctggcccgcacccaaagccagtggctg
attgatgtactggcgaaaacccatccgcaggtaaactttgagatggtgattattaaaact
aaaggtgatctggttcaggataaaccgcttgataaaattggcgacaagggcttgtttacc
aaggagttagaagatgcgctactatccggtgagatcgatatggccatccacagtatgaag
gatatgccgtcaaagctgccggaaggcctggtcttaacggtgccaccggttcgggaggat
gcccgggatgtcctgttgacaccccatcggattactgccctggatgagttgcccaagggt
gctgtggtggccaccggcagcaaacggcgaattgctcagctgcagaaactgcggccggat
gtggaaattgtgggtattcgtggtaacatcgatacccgaatccgcaaaatgcaggagcag
caattggatggcatcattctggcggcagccgggttaaaacggattggccgcttggaagac
tcagcctactacaccgtcgcactaccggaaaccacctttattccggcaccggcccagggt
attctggcggtggaagtccgggaagacaatcagacggttaacgaactgatggcagtcatc
agcgatcaaaatacgattgttcaaatgagcgccgaacggagttttttaaatgccttaaac
gggagttgtcatattcccgttggcgcattttgtgaaatagaagctgaagaaattacagta
tacggactgtatggtctggaagatgggagtcgggtggtgacccgatccataaaaggtgca
cctgaggaggcagaaaatttgggaaaacaattagctaaagcatgttatcaggcagtgcat
gaaaaaccgggaaaggtctatctggctggaggcggttgcggcgatcccggcctactgacc
gttaaagccaaggatattttgaccaaagccgatgtggtggtatatgatgctctggttaat
gaaagctttttaaacgatgcccgagctgatgctgaaattatctatgtcggcaaacgggcg
ggaaaccatgccatgcgtcaggaagatatcaatgccctgttagtccaaaaaggccaggaa
ggtaaattggtcctgcgcttaaaaggcggcgacccctatgtctttggccggggtggcgaa
gaaggggaagacctctatgacgctggggtaccctttgaagtgatccccgggattacctcg
gttatcggcggactggcttatgccgggattccgattacacatcgggactgtgtatcatcg
ttccatgttattaccggacatttaaaatcgaacgcctacgacggttcatcagatctggac
tggccggtgctgggcaaactcaaaggcacgatcgtctttttaatgggcgttaaaaatctg
gaaaagatctgtgacgaactggttaaaaacggcatgaatccggaaatgccagtggctgtg
gtccatcgggcctccaccccctatcagcgggtcgtaaccggaaacctgaccaccatctat
gatattgccgcggaagcaaaaatcacggcgccgagcctgattgtggtcggcgaagtcgtg
aataaaaggcaaaaactgcgcttctttgatgaaaaaccattgtttggcaaaaacattatc
gtcacccggtcccgggaacagagttctcaaatggttgaaaagatcacggagttgggtggc
aatgccattgaattcccaaccatcaaaattgtccccattaacgaagccgcctgtgacgaa
aaggtgaagtgccttaaggactacagccatattatttttaccagcatcaatggcgtggaa
gtcttcttcgattcgttggcccgctgtggcaaagatgcccgagcctttggcaacctgcat
attaccgcgattggcgaaggtaccaaaaatgccctcttagcccggggcctgcaagccgat
tttgtgccggataaatatgtcggcgaagaactggtcagcggtctggtgccgctgctcact
aaagacagccgggtgctgatcccccgatctaaaaatgcccggatctatgtggtccaagaa
ttgtcaaaaatctgtccagtcgacgaggttcaaagctatgaaaccatccgcgaagatcat
gccacaattgatccgctggcaatgttaactaacaaagaaattgattatattacctttacc
agttccaccaccgtcgagttttttgtcgaaaaaattggcgccgcccatattgatgccatt
aacaccgcaaaatgcgtatcgattgggccccagacctcaaagaaatgtgttgagctgggt
atcactgtcgatatcgaagccgaaacctataccattcagggcatgctggatgcgattttg
aaggattcacagaaataa
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