Actinomadura welshii: ACN3XK_04020
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Entry
ACN3XK_04020 CDS
T10979
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase subunit PurL
KO
K23269
phosphoribosylformylglycinamidine synthase subunit PurL [EC:
6.3.5.3
]
Organism
aws Actinomadura welshii
Pathway
aws00230
Purine metabolism
aws01100
Metabolic pathways
aws01110
Biosynthesis of secondary metabolites
Module
aws_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
aws00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
ACN3XK_04020 (purL)
Enzymes [BR:
aws01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
ACN3XK_04020 (purL)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
AIRS_C
AIRS
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
XRQ10083
LinkDB
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Position
794429..798031
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AA seq
1200 aa
AA seq
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MSEQPHATGRATRESSDEPSMEWLGELKSDADDPELQPVDPSVTQAFEAMLEEAKPADRP
AAASPQPAGPAPQVPQPAAAQPGAPAQPPAGGQPAIQVDPAAMAVLRAAQPAPGADIEGP
EQEFARALAEERPGVDPSSTVPEPSGADPTLTAPDLDQPDLNQYVTPPPPTGTGTGPQRV
AGPGTGPQPAVGPGTGPLPAVGPGASPQPFAGPGTGPLPAVGPGTGPQPAVGSNTGPQAP
VHDDRRGTGPQPAVGPGTGPQPAVGPGTGPLPAVGPGASPQPFAGPGTGPQPAVGPGTGP
QPAVGSNTGPQAPVHDDRRGTGPQPAVGPGTGPQPAVGPGASPQPVVRPGTGPLPAVGHG
TGPQPAVGPGTGPQPAVGPGTGPQPAVGPGTGPQPVVGYGTGPLPAVGPRTGPQPVVRPG
TGPLPAVGSGTGPQPAIESSGPIYTGTDTVAIAAASSERPQPYAELGMNDEEYRRVRDIL
GRRPTSAELAIYSVMWSEHCSYKSSRVHLRQFGEKAPKTDKLLVGMGENAGVVDVGQGWA
VTFKVESHNHPSYVEPYQGAATGVGGIVRDIMSMGARPIAVMDSLRFGPADAPDTQRVLP
GVVAGIGGYANSLGLPNIGGETVFDACYGQNPLVNALCVGVMKHEDIQRATAPGPGNKVI
LFGALTGPDGIGGASVLASATFDDESHQKRPSVQVGDPFMEKLLIECCLELFNEDLVVGI
QDLGAAGVSCATTELAAAGTGGMHVDLDAVPLRDETLLPEEILMSESQERMMAVVTPDKV
ERFMEICERWEIPATVIGTVTDTGRLVMTWRGETIVDLPPTTAADEGPVYNRPLQPPHDL
GALQSDTPGRLTRPSNGDELRRTVLWLAGSPNLASKTWVTSQYDRYVLGNTVMAMPENAG
VVRIDDESGLGIALSLDGNGRYTRLDPYAGAQLALSEAFRNVAATGARPLAVTNCLNFGS
PEDPGVMWQFARAVEGLADGCQYLGIPVTGGNVSFYNQTGTAPINPTPVVGVLGVHDDVR
RRVNMGLTTDGATLALLGETREEFGGSEWAHVVYGHLGGLPPLVDLKAEAALASVLVSAI
RDGLVTVVHDLSDGGLSQTLVESCLRGSLGARITLPGDPFVALFSESVARAMVAVRPGAE
ARLAALCESAGIPVTQIGVAGGDSLSVTGHGPEGDQQELFSIPLYELREAHERMLPSYAD
NT seq
3603 nt
NT seq
+upstream
nt +downstream
nt
atgagcgagcaacctcacgccaccgggcgcgcgacccgggagtcctcggacgagccgtcg
atggagtggctcggcgagctcaagtccgacgccgacgacccggagctccagccggtcgac
ccgtcggtcacccaggcattcgaggccatgctggaggaggccaagcccgccgaccggccc
gcggccgcgtccccgcagccggccggcccggcgccgcaggtgccgcagcccgccgccgcc
cagcccggtgcacccgcccagccgcccgcgggggggcagcccgccatccaggtcgacccg
gccgcgatggccgtgctccgggccgctcagccggctccgggcgccgacatcgaagggccg
gagcaggagttcgcccgcgccctggccgaggagcgccccggcgtcgacccctcgtccacc
gtgcccgagcccagcggggcggacccgacgctcacggcccccgacctggaccagcccgac
ctgaaccaatacgtgaccccgcctccgccgaccggcacgggcaccggcccgcagcgcgtc
gccgggccggggaccggcccgcagcctgccgttggcccggggacgggcccgctgcccgcc
gtgggtccgggcgcgagcccgcagcctttcgccggtccggggacgggcccgctgcccgcc
gtgggtcccggcacggggccgcagcctgccgtgggctcgaacacgggcccgcaggcaccc
gtccacgacgaccgccggggcaccggcccccaacccgccgtgggccccggtacgggcccg
cagcctgccgttggcccggggacgggtccgctgcctgccgtgggtccgggcgcgagcccg
cagcctttcgccgggccggggacgggcccgcagcctgccgtaggccccggcacggggccg
cagcctgccgtgggctcgaacacgggcccgcaggcacccgtccacgacgaccgcaggggc
accggcccgcagccggccgttggcccggggacgggcccgcagcccgcggtcggccccggc
gcgagcccgcagccggtcgtccgccccggcaccggcccgctgcccgccgtcggccacggc
accggtccgcagccggccgttggcccggggacgggtccgcagccggctgtaggcccaggc
accggtccgcagcctgccgttggccccggtacgggcccgcagcccgtagtcgggtacggc
accggtccgctgcccgccgtcggccccaggaccggcccgcagcccgtcgtccggccgggc
accggtccgctgcccgcggtcgggtccggcaccggcccgcagccggccatcgaatcgtcc
ggcccgatctacaccggcaccgacacggtcgcgatcgccgccgcctcttcggagcgcccg
cagccgtacgccgagctggggatgaacgacgaggagtaccggcgcgtccgcgacatcctc
gggcgccgtcccacgtccgccgagctggcgatctactcggtgatgtggagcgagcactgc
tcctacaagagctccagggtgcatctgcgccagttcggcgagaaggccccgaagaccgac
aagctcctagtcggcatgggtgagaacgccggtgtggtggacgtcggccaggggtgggcg
gtcaccttcaaggtggagtcgcacaaccacccgtcctacgtggagccctaccagggcgca
gcgaccggcgtaggcggcatcgtccgcgacatcatgtcgatgggcgcccgacccatcgcc
gtcatggactcgctccgcttcggcccggccgacgcccccgacacccagcgcgtcctcccg
ggcgtcgtggcgggcatcggcggctacgccaactcgctcggcctgcccaacatcggcggc
gagacggtcttcgacgcctgctacgggcagaacccgctggtcaacgcgctgtgcgtcggc
gtgatgaagcacgaggacatccagcgcgcgacggcccccggccccggcaacaaggtcatc
ctgttcggtgcgctgaccggcccggacgggatcggcggcgcgtcggtcctggcgtcggcg
acgttcgacgatgagtcccaccagaagcggccgtcggtccaggtgggcgacccgttcatg
gagaagctgctcatcgagtgctgcctggagctgttcaacgaggacctcgtggtcggcatc
caggacctcggcgccgccggcgtgtcctgcgcgacgacggagctggccgcggccggcacc
ggcggcatgcacgtcgacctcgacgccgtcccgctccgcgacgagacgctcctccccgag
gagatcctcatgagcgagtcgcaggagcgcatgatggcggtcgtgacgcccgacaaggtc
gagcggttcatggagatctgcgagcgctgggagatccccgcgaccgtgatcgggaccgtc
accgacacgggccgcctggtcatgacgtggcggggcgagacgatcgtcgacctcccgccg
accaccgccgccgacgagggcccggtctacaaccgcccgctgcagccgccgcacgacctg
ggcgccctgcagtccgacaccccgggccgcctcacccgcccgtccaacggcgacgagctg
cgccgcacggtcctgtggctggcgggctcaccgaacctcgccagcaagacgtgggtgacg
tcgcagtacgaccggtacgtcctcggcaacaccgtcatggccatgccggagaacgcgggc
gtggtgcgcatcgacgacgagtccggtctcggtatcgcgctgtccctggacgggaacggc
cgctacacgcgcctggacccgtacgcgggcgcgcaactggccctctccgaggcgttccgc
aacgtcgccgcgacgggtgcgcggcccctggccgtcaccaactgcctcaacttcggctcc
ccggaggacccgggcgtcatgtggcagttcgcccgcgcggtcgagggcctcgcggacggc
tgccagtacctcggcatcccggtcaccggcggcaacgtcagcttctacaaccagacgggc
accgcaccgatcaacccgaccccggtcgtcggcgtcctcggcgtccacgacgacgtgcgc
cgccgcgtgaacatgggcctcaccaccgacggcgccacgctcgcgctgctcggcgagacc
cgcgaggagttcggcggctcggaatgggcgcacgtggtctacggccacctgggcggcctc
ccgccgctggtggacctcaaggctgaggcggcgctggcgtccgtgctcgtcagcgcgatc
cgcgacggcctcgtcaccgtcgtccacgacctgtcggacggcggcctgtcgcagacgctg
gtggagtcgtgcctgcgcggcagcctgggcgcccggatcaccctgccgggcgacccgttc
gtcgcgctgttcagcgagtcggtggcccgcgccatggtggcggtccggccgggcgccgag
gcgcgcctggcggccctgtgcgagtcggcgggcatccccgtcacgcagatcggcgtggcc
ggcggcgactcgctgagcgtgacgggccacggcccggagggcgaccagcaggagctgttc
agcatcccgctgtacgaactccgcgaggcccacgagcgcatgctccccagctacgccgac
taa
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