Brucella abortus 63 75: DK49_2556
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Entry
DK49_2556 CDS
T03461
Symbol
bkdA1
Name
(GenBank) 2-oxoisovalerate dehydrogenase subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
babt
Brucella abortus 63 75
Pathway
babt00280
Valine, leucine and isoleucine degradation
babt00640
Propanoate metabolism
babt00785
Lipoic acid metabolism
babt01100
Metabolic pathways
babt01110
Biosynthesis of secondary metabolites
babt01210
2-Oxocarboxylic acid metabolism
Module
babt_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
babt00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
DK49_2556 (bkdA1)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
DK49_2556 (bkdA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
DK49_2556 (bkdA1)
Enzymes [BR:
babt01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
DK49_2556 (bkdA1)
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Motif
Pfam:
E1_dh
OxoDH_E1alpha_N
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
AIJ79088
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Position
2:489079..490311
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AA seq
410 aa
AA seq
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MSDDVVLSLHVPEPEWRPGDAPDFSHVKIPRAGSVRRPEIDEKPEAMRDMAFSIIRVLNR
EGEAVGPWAGTLTDEELKDGLRHMMMLRAYDARMMMAQRQGKTSFYMQHLGEEAVSCAFR
KALRKGDMNFPTYRQAGLLIADDYPLVTMMNQIFSNEQDPLKGRQLPVMYSSKEHGFFTI
SGNLATQYTQAVGWAMASAISHDTKIAAAWIGDGSTAESDFHAALVFASTYKAPVVMNIV
NNQWAISTFQGIARGGSGTFAARGHGFGIPSLRVDGNDYLAVHAVAKWAVERARRNLGPT
IVEYVTYRAGGHSTSDDPSAYRPKAENDAWPLGDPILRLKNHLIKRGVWSEERHKQAEAE
VMDIVVSAQREAEAIGTLHDGRKPSMRDMFEDVYAETPPHLIRQRQEAGF
NT seq
1233 nt
NT seq
+upstream
nt +downstream
nt
atgagcgatgatgtcgtactttcactgcatgttcccgagccggaatggcgcccgggtgat
gcgccggatttctcccacgtcaagattccccgtgcaggcagcgtgcgcaggcccgaaatc
gatgaaaagccggaagccatgcgcgatatggcgttcagcatcatccgcgtgctgaaccgg
gaaggtgaggcggtaggcccatgggcgggcacgcttaccgacgaggaactgaaggacggg
cttcgtcacatgatgatgttgcgtgcctatgatgcgcgcatgatgatggcgcaacgtcag
ggcaaaacctcgttctacatgcagcatctgggtgaagaggcggtgagttgcgccttccgc
aaggcgctgcgcaagggcgacatgaatttcccgacctaccgccaggcgggccttctcatc
gcggacgactatcccctcgtcacgatgatgaaccagatattctccaacgagcaggacccg
ctgaaaggccgccagcttccggtgatgtattcctcgaaagagcatggctttttcaccatt
tccggcaatctggcgacgcaatatacgcaggccgtcggctgggcgatggcatcggccatc
agccacgacacgaagattgccgccgcatggatcggtgacggctcgacggcggaaagcgat
ttccacgccgcactggtcttcgcctcgacctacaaggccccggtggtgatgaacatcgtc
aacaaccaatgggctatttccacctttcagggcattgcgcgcggcggttccggcactttt
gcggcgcggggccacggcttcggcattccgtcgctgcgcgtcgatggcaatgactatctg
gccgtccatgcggtggcgaaatgggcggtcgaacgcgcgcggcgcaatctcggcccgacc
atcgtggaatatgtgacctatcgcgccggcgggcactccacttcggacgatccgtccgcc
tatcgccccaaggcggaaaatgacgcatggccgcttggcgatccgatcctgcggctcaag
aaccacctcattaagcgcggcgtgtggtcggaagagcgccacaagcaggcggaagccgag
gtgatggatattgtggtgagtgcgcagcgcgaggcggaagccatcggcacgctgcatgat
ggccgtaagccctccatgcgcgacatgttcgaggatgtctatgccgaaacgccgccgcat
cttatccgccagcgtcaggaggcggggttttga
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