Bacillus sp. 1s-1: CJO35_02775
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Entry
CJO35_02775 CDS
T11357
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
bacj Bacillus sp. 1s-1
Pathway
bacj00300
Lysine biosynthesis
bacj00550
Peptidoglycan biosynthesis
bacj01100
Metabolic pathways
bacj01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
bacj00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
CJO35_02775
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
CJO35_02775
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
CJO35_02775
Enzymes [BR:
bacj01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
CJO35_02775
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ASV14144
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Position
551891..553366
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AA seq
491 aa
AA seq
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MEKGAEGGSPLDTAADTILICGSVSFPCRRKRGTYMITRTVKEIAEMSEGVLTNEAFEGR
LIKGVSTDSRKLAKGQLFIPLAGERFNGHVFAEQAFQEGVAAVLWNRSEPNPPEGKPVIL
VDDTLEALQKLAKAYRNQLDVKVVGVTGSNGKTTTKDMIHAVLGTEYKVHKTEGNYNNHI
GLPLTILAMPEDTEVAILEMGMSAKGEIDFLTRLARPDIAVITNIGESHLLELGSREGIA
EAKLEIVNGLSKEGTLIYVGDEPLLTERLNQPPYDTKTFGEDPAFDYQLEDMTQTEEGTA
FRVRGIENGFFIPVLGKHNVKNALAAIAAGDLLNVSRAHIAEGLTKLKVTGMRLELVKTP
DGVAIINDAYNASPTSMKAAIELVEQMKGYGKKILVLGDMLELGEGEKAFHEEIGQAVNP
DSIDFLFTYGELGAYIAKGALKHFPEHRVLHFNPEEKDSLKKTLKEKANTGDLILVKASR
GMRLEDVIKDL
NT seq
1476 nt
NT seq
+upstream
nt +downstream
nt
atggagaaaggcgctgaaggcggttcgcccttagatacagctgcagacactatccttatt
tgtggtagtgtctcttttccttgcagaagaaagagagggacatacatgataacaagaacg
gtaaaagaaattgctgaaatgtcggaaggcgttttgacgaatgaagcttttgaagggcgt
ctcatcaaaggcgtctcaaccgattcgagaaaactggcgaaaggccaactgtttattccg
cttgcaggcgagcggttcaacggacacgtttttgcagagcaggcttttcaggaaggcgtt
gcggccgtgctgtggaaccgaagtgaaccgaatcctccggaagggaagccggtcatttta
gttgacgatacgctggaagcgctgcagaagcttgcgaaggcatacaggaatcagctggac
gtaaaagtcgtcggcgtgaccggttcaaacggaaaaacgacgacaaaagacatgattcat
gctgttttgggcactgagtataaagtgcataagacagaaggaaactacaataaccatatc
ggcctgcccctgacgattctggcgatgcccgaagacacagaagtcgccattttggaaatg
gggatgagcgccaaaggagaaatcgattttctcactcgtctggcgcggcctgatattgca
gtcattacaaacattggtgaatcacacctccttgaactcggatcaagagaaggaattgca
gaggcgaagctcgaaattgtcaatgggctttcaaaagaaggcacactcatttatgtcgga
gatgaaccgctgctcaccgaaaggctgaaccagccgccttacgatacaaagacgtttgga
gaggatccggctttcgattatcagcttgaggatatgacacagactgaagaggggacggca
ttccgcgtgagaggaatcgaaaacgggttcttcatcccggtccttggaaagcataatgtg
aaaaacgcattagccgcgattgcggccggagacctcttgaatgtcagccgcgctcacatt
gcagaagggctgactaaactgaaagtgaccggaatgcggcttgagctagtaaagacgccg
gacggcgttgcgatcattaatgacgcctataatgccagcccgacatcgatgaaagcggcg
atcgagcttgtcgaacagatgaagggatacggcaagaagattcttgttctcggcgatatg
ctggagctcggagaaggagaaaaagcgtttcatgaagaaatcgggcaggcggtcaacccg
gactcgatcgactttttatttacgtatggagaactcggtgcatatattgcaaaaggggcg
cttaaacatttcccggaacaccgcgtccttcatttcaacccggaagaaaaagacagtttg
aaaaagacactgaaagaaaaagcgaatacaggggatttaatcctcgtcaaagcgtccaga
ggcatgcgccttgaggatgttataaaagatttgtaa
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