KEGG   Balaenoptera acutorostrata scammoni (minke whale): 103009947
Entry
103009947         CDS       T03086                                 
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
bacu  Balaenoptera acutorostrata scammoni (minke whale)
Pathway
bacu01522  Endocrine resistance
bacu04010  MAPK signaling pathway
bacu04015  Rap1 signaling pathway
bacu04068  FoxO signaling pathway
bacu04071  Sphingolipid signaling pathway
bacu04114  Oocyte meiosis
bacu04148  Efferocytosis
bacu04218  Cellular senescence
bacu04261  Adrenergic signaling in cardiomyocytes
bacu04370  VEGF signaling pathway
bacu04380  Osteoclast differentiation
bacu04517  IgSF CAM signaling
bacu04550  Signaling pathways regulating pluripotency of stem cells
bacu04611  Platelet activation
bacu04613  Neutrophil extracellular trap formation
bacu04620  Toll-like receptor signaling pathway
bacu04621  NOD-like receptor signaling pathway
bacu04622  RIG-I-like receptor signaling pathway
bacu04625  C-type lectin receptor signaling pathway
bacu04657  IL-17 signaling pathway
bacu04658  Th1 and Th2 cell differentiation
bacu04659  Th17 cell differentiation
bacu04660  T cell receptor signaling pathway
bacu04664  Fc epsilon RI signaling pathway
bacu04668  TNF signaling pathway
bacu04670  Leukocyte transendothelial migration
bacu04714  Thermogenesis
bacu04722  Neurotrophin signaling pathway
bacu04723  Retrograde endocannabinoid signaling
bacu04728  Dopaminergic synapse
bacu04750  Inflammatory mediator regulation of TRP channels
bacu04912  GnRH signaling pathway
bacu04914  Progesterone-mediated oocyte maturation
bacu04917  Prolactin signaling pathway
bacu04926  Relaxin signaling pathway
bacu04932  Non-alcoholic fatty liver disease
bacu04933  AGE-RAGE signaling pathway in diabetic complications
bacu04935  Growth hormone synthesis, secretion and action
bacu04936  Alcoholic liver disease
bacu05014  Amyotrophic lateral sclerosis
bacu05020  Prion disease
bacu05022  Pathways of neurodegeneration - multiple diseases
bacu05132  Salmonella infection
bacu05133  Pertussis
bacu05135  Yersinia infection
bacu05140  Leishmaniasis
bacu05142  Chagas disease
bacu05145  Toxoplasmosis
bacu05152  Tuberculosis
bacu05161  Hepatitis B
bacu05163  Human cytomegalovirus infection
bacu05167  Kaposi sarcoma-associated herpesvirus infection
bacu05169  Epstein-Barr virus infection
bacu05170  Human immunodeficiency virus 1 infection
bacu05171  Coronavirus disease - COVID-19
bacu05205  Proteoglycans in cancer
bacu05208  Chemical carcinogenesis - reactive oxygen species
bacu05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
bacu05415  Diabetic cardiomyopathy
bacu05417  Lipid and atherosclerosis
bacu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:bacu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103009947 (MAPK12)
   04015 Rap1 signaling pathway
    103009947 (MAPK12)
   04370 VEGF signaling pathway
    103009947 (MAPK12)
   04668 TNF signaling pathway
    103009947 (MAPK12)
   04068 FoxO signaling pathway
    103009947 (MAPK12)
   04071 Sphingolipid signaling pathway
    103009947 (MAPK12)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    103009947 (MAPK12)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    103009947 (MAPK12)
  09143 Cell growth and death
   04114 Oocyte meiosis
    103009947 (MAPK12)
   04218 Cellular senescence
    103009947 (MAPK12)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    103009947 (MAPK12)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    103009947 (MAPK12)
   04613 Neutrophil extracellular trap formation
    103009947 (MAPK12)
   04620 Toll-like receptor signaling pathway
    103009947 (MAPK12)
   04621 NOD-like receptor signaling pathway
    103009947 (MAPK12)
   04622 RIG-I-like receptor signaling pathway
    103009947 (MAPK12)
   04625 C-type lectin receptor signaling pathway
    103009947 (MAPK12)
   04660 T cell receptor signaling pathway
    103009947 (MAPK12)
   04658 Th1 and Th2 cell differentiation
    103009947 (MAPK12)
   04659 Th17 cell differentiation
    103009947 (MAPK12)
   04657 IL-17 signaling pathway
    103009947 (MAPK12)
   04664 Fc epsilon RI signaling pathway
    103009947 (MAPK12)
   04670 Leukocyte transendothelial migration
    103009947 (MAPK12)
  09152 Endocrine system
   04912 GnRH signaling pathway
    103009947 (MAPK12)
   04914 Progesterone-mediated oocyte maturation
    103009947 (MAPK12)
   04917 Prolactin signaling pathway
    103009947 (MAPK12)
   04926 Relaxin signaling pathway
    103009947 (MAPK12)
   04935 Growth hormone synthesis, secretion and action
    103009947 (MAPK12)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    103009947 (MAPK12)
  09156 Nervous system
   04728 Dopaminergic synapse
    103009947 (MAPK12)
   04723 Retrograde endocannabinoid signaling
    103009947 (MAPK12)
   04722 Neurotrophin signaling pathway
    103009947 (MAPK12)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    103009947 (MAPK12)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    103009947 (MAPK12)
  09159 Environmental adaptation
   04714 Thermogenesis
    103009947 (MAPK12)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    103009947 (MAPK12)
   05208 Chemical carcinogenesis - reactive oxygen species
    103009947 (MAPK12)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    103009947 (MAPK12)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    103009947 (MAPK12)
   05161 Hepatitis B
    103009947 (MAPK12)
   05171 Coronavirus disease - COVID-19
    103009947 (MAPK12)
   05163 Human cytomegalovirus infection
    103009947 (MAPK12)
   05167 Kaposi sarcoma-associated herpesvirus infection
    103009947 (MAPK12)
   05169 Epstein-Barr virus infection
    103009947 (MAPK12)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    103009947 (MAPK12)
   05135 Yersinia infection
    103009947 (MAPK12)
   05133 Pertussis
    103009947 (MAPK12)
   05152 Tuberculosis
    103009947 (MAPK12)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    103009947 (MAPK12)
   05140 Leishmaniasis
    103009947 (MAPK12)
   05142 Chagas disease
    103009947 (MAPK12)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    103009947 (MAPK12)
   05020 Prion disease
    103009947 (MAPK12)
   05022 Pathways of neurodegeneration - multiple diseases
    103009947 (MAPK12)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    103009947 (MAPK12)
   05418 Fluid shear stress and atherosclerosis
    103009947 (MAPK12)
   05415 Diabetic cardiomyopathy
    103009947 (MAPK12)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    103009947 (MAPK12)
   04932 Non-alcoholic fatty liver disease
    103009947 (MAPK12)
   04933 AGE-RAGE signaling pathway in diabetic complications
    103009947 (MAPK12)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    103009947 (MAPK12)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:bacu01001]
    103009947 (MAPK12)
Enzymes [BR:bacu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     103009947 (MAPK12)
Protein kinases [BR:bacu01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   103009947 (MAPK12)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH Kdo Haspin_kinase
Other DBs
NCBI-GeneID: 103009947
NCBI-ProteinID: XP_007189385
LinkDB
Position
Un
AA seq 442 aa
MQGAQVAVGSHVSKSPLLLGGAPRSSAVDSRTGAKVAIKKLYRPFQSELFAKRAYRELRL
LKHMRHENVIGLLDVFTPNETLDDFTDFYLVMPFMGTDLGKLMKHEKLSEDRIQFLVYQM
LKGLKYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADSEMTGYVVTRWYRAPEVI
LNWMHYTQTGEELPGDAAPQHQLPRPPLPELLCGEAAELGRGWAGRGRLDGSWAHAPLHC
PHSRVCVCPPPQPTGPWQRPYPTLGAGCGGGLPYTCGEQARHTAQAGWVGELCSLALHCA
PDLSQDLDQLKEIMKVTGTPPPEFVQRLQSAEAQNYMKGLPELEKKDFASILTNASPLAV
NLLEKMLVLDAERRVTAAKALTHPYFESLHDTEDEPTAQKYDESFDDVDRMLDEWKRVTY
REVLSFKPPRQLGAKVSKETAL
NT seq 1329 nt   +upstreamnt  +downstreamnt
atgcaaggggctcaggtggccgtgggcagccatgtgagcaaaagccccctgctccttggc
ggtgcgccccgcagctcggccgtggacagccgcacgggcgccaaggtggccataaagaag
ctgtaccggcccttccagtccgagctgttcgccaagcgcgcctaccgcgagctgcgcctg
ctcaagcacatgcgccatgagaacgtaattgggctgctggatgtgttcacacccaatgag
accctggatgatttcacagacttttacctggtgatgccgttcatgggcaccgacctgggg
aagctcatgaagcacgagaagctgagtgaggaccggatccagttcctcgtctaccagatg
ctcaaggggctgaagtacatccacgctgctggcatcatccacagggacctgaagcccggc
aacctggccgtgaacgaggactgtgagctgaagatcctggactttggcctggcccggcag
gcagatagcgagatgactggatacgtggtgacccggtggtaccgggcgcctgaggtcatc
ttgaattggatgcactacacacagacgggtgaggagctgcccggagatgcggccccgcag
caccagcttcctaggccgcccctgccggagctgctctgcggggaggctgctgagctgggc
cggggctgggcagggcgtggtaggctcgatggctcctgggcccatgcccccctccactgc
ccccactcccgcgtctgtgtgtgcccccctccccagcccacagggccctggcagcgaccg
tatcctacacttggagccgggtgcgggggaggcttgccctacacctgcggggagcaggcc
aggcacactgcccaggctgggtgggtaggtgagctctgctctctggccctgcactgtgct
cctgacctcagccaagacctagaccagctgaaggagatcatgaaggtgacggggacgcct
ccccctgagttcgtgcagaggctgcagagtgccgaggctcagaactacatgaagggcctc
cctgagctagagaaaaaggattttgcctccatcctgaccaacgcgagccctctggccgtg
aacctcctggagaaaatgctggtgctggatgcggagcggcgggtgacggcggccaaggcg
ctgacccacccctacttcgagtcgctgcacgacacagaggacgagcccacggcccaaaag
tacgatgaatcctttgatgacgtggaccgcatgctggacgagtggaagcgtgtcacatat
agagaggtgctcagcttcaagcctccccgacagctgggggccaaggtctccaaggagacg
gccctgtga

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