Balaenoptera acutorostrata scammoni (minke whale): 103014349
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Entry
103014349 CDS
T03086
Symbol
SETX
Name
(RefSeq) senataxin
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
bacu
Balaenoptera acutorostrata scammoni (minke whale)
Pathway
bacu05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
bacu00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
103014349 (SETX)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
bacu03021
]
103014349 (SETX)
Enzymes [BR:
bacu01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
103014349 (SETX)
5.6.2.5 RNA 5'-3' helicase
103014349 (SETX)
Transcription machinery [BR:
bacu03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
103014349 (SETX)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
AAA_11
AAA_12
UvrD-helicase
AAA_19
AAA_30
AAA_22
Viral_helicase1
nSTAND3
ResIII
AAA_16
SLFN-g3_helicase
Helicase_RecD
UvrD_C_2
CxC6
Motif
Other DBs
NCBI-GeneID:
103014349
NCBI-ProteinID:
XP_007194522
UniProt:
A0A384B4G6
LinkDB
All DBs
Position
Un
AA seq
2680 aa
AA seq
DB search
MSTCCWCTPGGISTIDFLQRYASETHSSEFRTADEDLCYCLECVAEYHKARDELPFLHKV
LWELETSRLINHFEKAMKAEIGDDDELYIIDSNGEAQLFDFTGQDFENKLRVPLLEILKY
PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK
VDRDDYYDLQEVLTCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTANYKNYWLG
ICMLLTILEEQAMDSLLLGSNKQNDFMQSILHTMERQSDDDSVDPFWPALHCFMVILDRL
GSKVWGQLIDPIEAFQTIINNVSYNKEIQNIRNSSVRSKLEAQSYLDDTVTCSQIVYNYN
PEKTKKDSGWRSAICPDYCPNMYEEMETLANVLQSDIGQDMRVHNSTFLWFIPFVQSLMD
LKDLGVAYIVEVIHHLHSEVKDVLNQTDAVCDTVTEFFLLILVSVIELHRNKKCLHLLWV
SSQQWVEAVVKCAKLPTTAFARSSEKSSGNCAKGTTMITSLSLHSVPSNSVQLACVQLIR
SLLKEGYQLGQQTLCKRFWDKLNLFLRGNLSLGWQLTSQETHELQTCLKQIIRNTKFKVP
QCSTSVDLTPPASYNKEESEQTGKKSKKDRHCLENSSPTFSKEAMKADACQVQESIFSKA
NNAIEEDNEQTYIKDLKLEDHFSAELCLKPSSKRLVNERARGQVKISTGKHKSVKENSSY
TPQNCTSRNGPEKVFDRGIITSTRLWTDSSSDSLEKVSTSNEDFSLKDDALGKTSKAKTK
AHKDEICAKLSHVIKKQHRKSITLEENLTVSSIESFYSKKDTGGQKGYGFIHNPSSGPNG
ILDDKNGEQKSENSLLLKKKQVKEEELGIFSTPEISCQILECHVDNKDLVSFTEMTNIFV
EKTPPFKDPVTGLESRDTEISKSTVQFSSNLREQALSISHNSDTLTDSQIDRDLHELSLI
AQASVTKFPSDSTKKKSLSQLQRKVKDDRRRFTANKNSVRETCCGQVIIISDSDEDDEND
DERIVGFKKHIRQGKTCIEKDCPEQHTSIANTNVEQKVKEENTRSLLQFEESDSQFFEFE
SPCEVFSVWQDQKPDNKNSVQENEENSCLTHITNDGGYDTDYVPEEVIKKAAEGIEEHAE
PHSSSISVEKFCEIEVKKPKRKRYKKAAMAEDPVRPSSPVKSEDQSDILNERDVTENDFK
SIDIRTTTPSSSIQRTTTVSLKRSPPKLRTYSKPVRRVSLSKTPKKTHSDTKTGQSKSLN
YLSCRTTPAIVPPKKFRQCPEPTSTVEKLGLKKAPRRAFELSQRSLECLAQLRDHGKTVG
VVDTRKKTKLISPQALSVKNNKKLLTSQDLQLRRQRRPRSQQNRQGCFDYQSTDTARAGP
HAAQNSDKFVPESDTSDYSYKRGAEVTAKSKEKQLIKCVSSETEPTKAKYVSQVADDTCL
LNQCNSVVLNGEIPTNEIVVSTSGDPLGGGDLTVHHLDVAALKEGEPESSSDIEEDNIFL
TQCDPEDMDLCSQMEKENDKLIEVVHGKDTVQVEEDSVSRPQLESLSSTKCKYKDCVETL
KNQGEYCSKHSEAKAADEDIFRKPGLPLSASKPSRPSTAKIFSSSSTSRIAGLSKSLENT
SALLPTLKNKSSGVQSVLKVPQPASLVSQKPVAEVKGLCNVLRSHTPNNSNRQGYEVPFG
ENRSFLATSPVNILWSAQSISDTFVEEILKWKYEMFVNFDHCGPPSTLCQSIARHVPVRF
QDCGDYFSVFFPLMVLNTFETVAQEWTSSPNKEKFHQFHLRKFXXXAEYKKYWEFVVYLD
ECELAKQLHPKENDLVFLVPERLNGEKKDIERHRMQDPHEYYCGYVHKFRRTSVMRNGKS
ECSLSIQTQHNLPVNLNEFVKCLVISSLVTTQRKLKAMSLLSGRSQLARAVLNPNPMDFC
TKDLLTTASERIIAYLKDFNEDQKKAIETAYAMVKHSPAVAKICLIHGPPGTGKSKTIVG
LLYRLLTERRGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGN
CGDINLVRLGPEKSINTEVLKFSLDSQVNHRMKKDLPSHIQEMHRRKEFLDHQLDELSRQ
RALCRGGRELQRQKLDEKIAKVSKERQELASKIKEVQGRPQKTQNIIILESHIICCTLST
SGGLLLEAAFRGQGGVPFSCVIVDEAGQSCEVETLTPLIHRCSKLILVGDPKQLPPTVIS
VKAQDYGYDQSMMARFYKLLEENVEHNVIGRLPVLQLTIQYRMHPDICLFPSNYVYNRSL
KTNRLTETIRCSSEWPFQPYLVFDVGDGSEKRDNDSYVNVQEIKLVMEIIKLIKDKRKDV
TFRNIGIITHYKAQKMMIQKDLDKEFDGKGPAEVDTVDAFQGRQKDCVIVTCVRANAMQG
SIGFLASLQRLNVTITRAKYSLFILGHLRTLMENQHWNHLIQDAQKRGAIIKTWGKNYRR
DAVKILKLKPVLQRGLAHPPAVAPEASTPQGGVPSNQLDSAFAKMSFASSPYPSPSDSKE
ATVTVTAKDPERPPIQDRLRDPRLLRRMGLGCEAKGKCLSELQPSSPQYPGATPPLGEPG
FPGSHQDPTSIGQQPPAKGAAVNNHSPHAQCDAPAASTNASTSKRAQEGGALSHRRETRA
FTEGDQERRGSLSHHTKRNSGWDERGLEEEDSSLKKRRLL
NT seq
8043 nt
NT seq
+upstream
nt +downstream
nt
atgagcacatgttgttggtgtacgccaggtggtatttccaccattgacttcctgcaacgc
tatgcatccgagacccactccagtgaatttcgaacagctgatgaagacctctgctactgc
ttagagtgtgtggctgaataccacaaagcaagggacgaattgccattcttacataaggtt
ttatgggaattagaaacctcacgtctcataaatcactttgaaaaggccatgaaagcagaa
attggagatgatgacgagttatatataatagacagcaatggagaggcacagctgtttgac
tttactggccaagactttgaaaataagcttcgagttcctcttcttgaaatactgaaatat
ccttacttgcttttacatgaacgtgttaatgaattatgcgttgaagcactttgccggatg
gaacaagctaattgctcctttcaggtttttgacaaacatccagggatatatttgtttttg
gtccatcccaatgaaatggttcggcgttgggctatcctgaccgcaagaaacttgggaaaa
gtagacagagatgattattatgacttacaggaggttttgacttgcctttttaaagttatt
gagttggggcttttagaaagtccagacatttatacttcttctgtccttgagaagggtaaa
ctgattcttctgccttcacacatgtatgatactgccaactacaaaaactattggttaggt
atttgcatgttgctgaccattcttgaggagcaagccatggattcactgttgttgggctca
aacaaacagaatgattttatgcaatcaatacttcacaccatggagaggcaatcagatgat
gatagtgtggatcctttctggccagcgttacactgtttcatggtgattctggatcgcctt
ggatctaaggtctggggtcaacttattgatcctattgaggcatttcaaaccattatcaac
aacgtgagctacaataaagagatccagaatatacggaacagctctgtgaggagcaagtta
gaagcgcagtcgtatttggatgatacggtgacttgcagccagattgtatacaattataac
cctgaaaagaccaaaaaggattcagggtggagatcagccatttgcccagattattgtcct
aacatgtatgaagaaatggaaacattagctaatgtgcttcagtcagatatcggtcaagac
atgcgtgttcataacagcacgtttctgtggttcatcccttttgtgcagtccctcatggat
cttaaggatctgggtgtggcttatatagtggaggttattcatcatctgcattctgaagtc
aaagacgtcctcaaccagacagacgccgtgtgtgacacagtcactgagtttttccttctc
attttggtgtcagtgattgaacttcatagaaataaaaagtgtttgcatttgctgtgggtt
agttcccagcagtgggtggaagccgtcgtaaaatgtgccaagcttcccaccaccgcgttt
gcacggagttctgagaagtcgtctggaaactgcgccaaaggcacaacaatgataacatct
ctgtcattgcattcagtgccatctaactctgtacaacttgcttgtgtgcagctgatcaga
agtctccttaaagaaggctatcagcttgggcagcagactctttgtaagcgattctgggat
aagctcaacttattcctgcgaggaaatttatctttaggttggcagttgactagtcaggaa
acccatgagttacaaacttgtttaaagcaaattattagaaacacaaaattcaaagtacct
caatgtagcacttctgtggatctgactcctcctgcatcttataataaagaagaaagtgaa
caaacagggaagaagtctaaaaaagacagacactgtctggaaaactccagcccaacattc
tctaaagaagcaatgaaagctgatgcatgtcaagtgcaagagagtattttcagcaaagca
aataatgccatagaagaggataatgagcaaacttatataaaagatttgaaactcgaagac
catttctcagctgagttgtgcttgaagccgagtagtaaaaggcttgttaatgaaagagct
cgaggccaagttaaaataagtacagggaagcataagtctgtaaaagagaattcctcatat
accccacagaattgtacttcaagaaatggtccagaaaaggtatttgacagaggaataata
acatcaacacgtctgtggactgattctagcagtgactctctggaaaaggtgtccacatcc
aatgaggatttctctttaaaggatgatgctcttggcaaaacctcaaaagcaaaaactaag
gcacataaagatgaaatctgtgctaagttatcacatgtcataaaaaagcagcacaggaaa
agtatcactttagaggaaaacctgactgtatctagcatcgaaagtttctattcaaagaaa
gatacaggaggtcagaaaggatatggcttcatacacaatccttcttcaggccctaatggt
attctggatgataaaaatggagaacaaaaatctgaaaacagtttattgctgaaaaagaaa
caagtaaaggaagaagagttaggcattttctctacccctgaaatcagttgtcaaatactg
gaatgtcatgttgataataaagatttggtctcatttacagaaatgaccaatatttttgtg
gagaaaacacctccctttaaagatcctgtgactggacttgaatcaagagatacggaaatt
agcaagagtaccgttcagttttcttctaatttaagagaacaggcccttagcatcagtcat
aattctgacaccttaacagattctcagatagacagagacctccacgaattatctttaata
gctcaagccagtgttactaagttcccatcagattcaactaaaaaaaaaagtctatcccag
ctacaaagaaaagttaaagatgatagaagacgtttcacagccaacaaaaatagtgttagg
gaaacctgctgtggacaggtaattattatttcagattctgatgaagatgatgaaaatgat
gatgaaagaattgtgggttttaagaaacacattagacagggtaaaacatgcattgagaaa
gactgtccagagcagcatacttcaatagctaacacaaatgtggaacagaaggtaaaagaa
gaaaatacaaggtcccttttgcagtttgaggaatctgattctcagttttttgagtttgaa
agtccatgtgaagtgttttcagtttggcaagatcagaaaccagacaacaagaattcagtt
caagagaatgaagaaaattcgtgcttgactcatatcacaaatgatgggggttatgataca
gattatgtacctgaagaggtcattaaaaaagcagcagagggcattgaggaacacgcagaa
ccacacagtagtagtatttctgttgagaaattttgtgaaattgaagtgaagaaacccaag
agaaaacgatacaagaaagctgctatggctgaagatcctgtaaggccttcatctcctgtc
aaaagtgaggaccagtctgatattcttaatgagagagatgtgactgaaaatgattttaaa
agtatagacataaggactacaactcccagttcaagcattcagagaaccactactgtttcc
ctgaagaggtctccaccaaagcttcgcacttattccaaacctgttaggagagtctcactt
tctaaaactcctaaaaaaacacattcggataccaaaacaggacagagtaaaagtttaaat
tacctaagttgtagaacaactcctgctatagtgccaccaaagaaatttcgccagtgtcct
gaaccaacttcaacggttgagaaacttggtctgaaaaaggctcctcgtagggcatttgag
ttgtcccagcgatctttggagtgtttagctcagttacgtgaccatggcaaaactgttgga
gtagttgatacccggaaaaagactaagttaatttctcctcaggctctctctgtcaaaaat
aataagaaactgctgacgagtcaagaccttcagttgcgaaggcagaggagacccagatca
caacaaaacagacaaggatgttttgattatcaaagtacagatacagcacgagccgggcca
catgcagcacagaattctgacaaatttgtgccagaatcagatacatcagattatagttat
aaaagaggagctgaggtaactgctaaaagtaaggaaaaacagttaataaaatgtgtgtct
tctgaaacagaacccacgaaagcaaaatatgtttctcaggtagctgatgacacttgtctt
ttgaaccagtgtaattctgtagtgttaaatggagaaataccaacaaatgaaatagttgtt
tctacctcaggggaccctttaggtggaggtgacctaacagtacatcatttagatgtggca
gctttgaaagagggagagcctgaatccagcagtgacatagaggaagataatatattttta
acacaatgtgatcctgaagatatggatttatgttcacaaatggagaaagagaatgataaa
ctcattgaagtagttcatggaaaagatacagtccaggtagaagaagattctgtgagtcgg
cctcagttggaatctttgagtagcacaaaatgtaagtacaaagattgtgttgaaacactg
aaaaaccagggtgaatactgttcaaaacactctgaagctaaagcagcagatgaagatata
tttcgtaaacctggcttgcctctctctgcatctaaaccttcgagaccttccactgctaag
atttttagctccagtagtacttcacgaattgctggtctttccaagtctttggaaaatacg
tcagcgctcctaccaactctgaaaaataagtcaagtggggtacaatctgttttgaaagta
ccacagccagcctctctggtgtctcagaagccagtggctgaagtgaagggtttgtgcaac
gttctccgttctcatactccaaataattccaacaggcaaggctacgaagttccatttggt
gaaaacagatctttcttggctacttctccagtaaacattctctggtcagcacagtccatc
tctgacaccttcgttgaagagatcttaaaatggaaatacgaaatgtttgtgaactttgat
cattgcggacccccgtcaactctttgtcagtccatcgcaagacatgtgcctgtgagattt
caagattgtggagattattttagtgtgtttttccctttgatggtactgaatacttttgaa
acagtggcacaggaatggaccagctctccaaacaaagagaaattccatcagtttcattta
cgaaaatttnnnnnnnctgctgagtataaaaaatactgggagtttgtggtttatcttgac
gaatgtgaactagctaaacagcttcatccaaaggaaaatgatttggtgtttttggttcct
gaaagactaaatggagagaagaaggatatagagagacatcgcatgcaagatccccatgag
tattattgtggttatgtccataaattccgccgcacttcagtcatgcgtaatgggaaatcg
gagtgttccctttccatccagacgcaacataatttaccagtcaatttaaatgaattcgtg
aaatgtcttgtaatcagctctctggtgactacacaaaggaagttgaaagccatgtctttg
ctgagtggtcggagccaactggccagagccgttctgaatccaaaccccatggacttctgt
acaaaagatttactaactacagcatctgagagaattattgcctacctaaaagatttcaat
gaagaccaaaagaaagcgatagaaactgcatatgccatggtgaaacactccccagcagtt
gccaagatctgtctgattcatggaccacccgggacaggaaaatcaaaaaccattgtgggc
ctcctgtaccgcctactgacagagaggagggggcattcagatgagaactccaatgccaaa
atcaaacaaaaccgtgtccttgtgtgtgcaccttccaatgcagctgttgatgaacttatg
aaaaaaatcatccttgaattcaaagagaagtgtaaagacaagaagaatcctttgggaaac
tgtggagatataaatttagtacgtctaggtccagaaaagtctattaatactgaggtccta
aaattcagtttggacagccaagttaaccacagaatgaaaaaagacttaccttctcatatt
caggagatgcatagaagaaaggaatttctggatcatcaactagatgaactttcccgccag
cgtgctttatgccgaggtggaagggaactacagaggcaaaaattagatgaaaaaattgcc
aaagtttcaaaagaaaggcaggagcttgcttctaaaattaaagaggttcaaggacgccca
caaaagacacagaacatcatcatcttagagtcccacatcatctgctgcacactgagcacg
agtggtggtttgctgctcgaggctgctttccgtgggcaagggggtgtcccctttagttgc
gtcattgttgatgaggccgggcagtcttgtgaagttgaaactcttactccgctcatccat
cgctgcagcaagctcatcctcgtaggggaccctaagcagctccctcccacggtcatctct
gtgaaggcccaggattatggctatgaccagtcgatgatggcccgcttctacaaacttctg
gaagagaacgtggagcacaacgtgattggcaggctgcctgtcttacagctcaccattcag
tacaggatgcacccagacatatgtctcttcccttctaattacgtttataacaggagcttg
aaaacaaatagattgacagagactattcggtgttcatctgaatggccatttcagccctac
ctcgtgtttgatgttggagatggttcagaaaagcgggataatgactcatatgtaaatgtt
caagaaataaaactggtaatggaaataattaaacttataaaagacaaaagaaaggatgtt
actttccgaaacattggcataataacccattacaaggctcagaagatgatgattcagaag
gatttggacaaagagtttgatggaaaagggccagcagaagtagataccgtggatgccttc
cagggtcgtcagaaagattgtgttattgttacatgtgtcagagcaaatgccatgcaaggc
tcaattgggtttctggcaagtttgcagagattgaatgtcaccatcacacgagccaagtac
agcctcttcatcctgggacatttgaggaccctgatggaaaaccagcactggaatcacctg
attcaggacgcacagaagcgtggtgccatcattaagacttggggcaaaaactacaggcgc
gacgcggtgaagatcctgaaactcaaacccgtgctgcagagaggtctggctcaccctcct
gctgtcgccccagaggcgtccacaccccagggcggagtgcccagcaaccagctagacagt
gcatttgccaagatgtcctttgcttcttccccgtacccctcaccctctgactccaaagaa
gccactgtcactgttactgcaaaggaccctgaaaggccacccattcaggaccggcttcgg
gacccacgactgcttaggaggatgggcttgggctgtgaagccaaagggaaatgcctcagt
gagctgcagccctcgagcccccagtatcccggagcaacgcctcccttgggagagccaggc
ttccccggaagtcaccaggatccgaccagtatcgggcagcagccccccgccaagggagct
gctgtgaacaaccacagtcctcacgcgcagtgcgacgctccagctgctagtaccaatgct
tccacgagtaaacgtgcccaggaagggggggcactcagccacaggagggagaccagggcc
ttcactgagggggatcaggagaggcgtggctctctgagccaccacacgaagaggaactca
ggctgggacgagaggggactggaggaggaggacagtagcttaaagaagaggaggctttta
tag
DBGET
integrated database retrieval system
