KEGG   Brevibacillus agri: BA6348_15130
Entry
BA6348_15130      CDS       T05855                                 
Symbol
tycC
Name
(GenBank) tyrocidine non-ribosomal peptide synthetase TycC
  KO
K16124  tyrocidine synthetase III
Organism
bagr  Brevibacillus agri
Pathway
bagr01054  Nonribosomal peptide structures
Brite
KEGG Orthology (KO) [BR:bagr00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01054 Nonribosomal peptide structures
    BA6348_15130 (tycC)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins [BR:bagr01008]
    BA6348_15130 (tycC)
Polyketide biosynthesis proteins [BR:bagr01008]
 Nonribosomal peptide synthetase (NRPS)
  Linear NRPS
   Tyrocidine synthetase
    BA6348_15130 (tycC)
SSDB
Motif
Pfam: Condensation AMP-binding PP-binding AMP-binding_C Thioesterase Abhydrolase_3 Hydrolase_4
Other DBs
NCBI-ProteinID: QAV13981
LinkDB
Position
3056100..3075554
AA seq 6484 aa
MKKQENIAKIYPLTPLQEGMLFHAVKDTGSSAYCLQMSATIEGDFHLPLFEQSLNKLVEN
YEVLRTVFVYQNLQRPRQVVLKERKVAVAFENIAHLPTFEQNEYITAYKNQHHTFDLTKD
SLMKAAIFQTGENKYQFVWAFHHIIVDGWTLGVLLQKLLAYYAALRNGEPIPREATKPYS
EYIKWLDKQNKEAALTYWQNYLAGYDHQADFPKKKHSAEAGRYEHVESMFAIAPEQTQQL
MQIANQNQATMSSVFQALWGILASKYKNADDVVFGSVVSGRPPQIPGIESMVGLFINTIP
TRVQTNRQQSFSELLQTVQKQALASAAYDFAPLYEIQSTTVLKQALIDHLVTFENYPDHS
MKHLEDSLGFQLTVESGEEQTSYDLNVVVALAPSNELYVKLSYNAAVYEPSFVNRIEGHL
RTVIEQVIRNPHVRLHEIGIITEEEKQQLLVAYNDTAADYPRDKTIFALIAEQATRTPTK
IAAVCGDDSLTYQELMERSAQLAKALRDRGIGRGSIVSIMAEHSLELIVAIMAVLQSGGA
YLPIDPEYPLDRIQYLLDDSQTTILFTQSHLQPNIQFAGSILYLDDPSLYAGDSTPFAAE
SKPDDLAYMIYTSGSTGNPKGAMITHQGLVNYIWWANKVYVQGEAVDFPLYSSISFDLTV
TSIFTPLLSGNTIYVYRGADKVQLILDIIRDNKVGIIKLTPTHLKLIEDVDGKASSIRRF
IVGGENLPTKLAKQIYDHFGQDVQIFNEYGPTETVVGCMIYLYDPQKTTQESVPIGVPAD
NVQLYLLDASMQPVPVGSLGEMYISGDGVAKGYFNRPELTEEKFIDNPFRPGTKMYRTGD
LAKWLPDGNMEYAGRIDHQVKIRGHRIEMGEIETRLTQHESVKEAVVIADKDESGQNVLY
AYFVSEQELTVAELRTFLGSTLPSYMIPSFFIRLAEIPLTANGKVERKKLPKPDGAVVTG
TAYVAAQNDIEAKLAEIWQQVLGMSQVGIHDDFFDLGGHSLKAMTVISQVAKALEVDLPI
KALFEHPTIAELARFLSQSEKSKHTAIQPVEAQEFYPVSSAQKRMYILQQFEGSGISYNI
SGAILLEGKLDYARFASAIQQLAERHEALRTSFHRIEPVQKVHAKVEVPLFMLESTEDKA
ENIMREFVRPFDLGVAPLVRTGLVKLGTDRHLFLLDMHHIISDGVSSQIWLREFAELYKG
AELPPLALQYKDFAAWQNEWFQTDAYKQQEQHWLNAFADEIPLLNLPTDYPRPSLQSFEG
DLVLFAAGKERLERLQQVAAETGTTLYMVLLAAYNVLLSKYTGQEDIIVGTPVAGRSHVD
VEQIMGIFVNTLAMRNQPASSKTFAQFLQEVKRNALAAYDHQDYPFEELVEKLAIQRDIS
RNPLFDTMFSLESASQKTLAIDRLTVSPYELFNKISKFDLVLNASESPADIQFQLTFATR
LFKKETVQRMAEHYLEILRAISERPTVKLADIDMMTEAEKRALLLNVNDTFVERTTAMAL
HQFVEEQAARTPDEVAVAYEGHALTYRELNARANQLARLLRSQGTRPGTLIGIMVDRSPG
MVVGMLAVLKAGGAYTPIDPSYPAERIRYMLRDSEAPILLTQRHLQETVAYAGAIIDVDE
EAIYTGDDTNLDNVAGQDDLAYVIYTSGSTGKPKGVMISHQAICNHMLWMRETFPLTTED
AVLQKTPFSFDASVWEFYLPLMTGARLVLAKPDGHRDIAYMTRLICEQNITTLQMVPSLL
DLVMTDPGWSACTSLQRVFCGGEALTPALVSRFYETQQARLINLYGPTEATIDATYWLCP
RQQEYSVIPIGKPIDNVRLYVVNASNQLQPVGVAGELCIAGDGLARGYWQREELTQASFV
DNPFEPGGRMYRTGDMVRYLPDGEIEYVGRIDHQVKIRGHRIELGEIEAKLLQHEAVKAA
VVIARQDGNGQNSLSAYVVAKQDIQTAELRTYLSAALPAYMVPSAFVFLEQLPLSANGKV
DRQALPQPEDAAAADSMYVAPRNELEAKLAQMWESVLGVERIGVHDHFFELGGHSLKAMN
VIALIQRTFQAEVPLKALFESPTIASFAPIVAAASKGANTAIQPVEKQEYYPVSAAQKRM
YILQQMEGAGISYNMPGFLYLDGKLDTERLQQALNRLVQRHESLRTSFHSVQGETVQRVH
EDVELAISFGEATEAEIRQIAERFIQPFDLGTAPLWRAGLIKLAPERHLFMLDLHHIVAD
GVSIGLLIQEFARLYRGEELPELRIQYKDFAKWQNDWFQTDEFAAQEAYWIDRFAEDIPV
LNLPTDYPRPSVKSFAGDRFVFGSGTALQKELHQLAHKTGTTLYMVLLAAYNVLLSKYSG
QEDIVVGAPTAGRSHAETKSIVGMFVNTLALRNEPAGDKAFHSFLAEVKANTLKAFEHQD
YPLDELVDKLNIQRDLSRNPLFDTVFILQNMEQKPFAMERLTVTPYATEVKQAKFDLSLE
AYEENAEIVFSLDYCTKLFSRETMKNVAAHFLQILRVVAANPEVLLSEIAMLTAEEKQRL
LVDFNDTHKDFPQDKTLSALFEEQAEKTPQATAVEIGEQQLSYRELNERANQLAATLRER
GVKPDQTVGIMVNRSVEMAVGILAILKAGGAYVPIDPEYPEERIAYMLADCEARLVLAQK
HLGPKLGSGVSAECLYVDDESAYSAQRANLQPIHTASDLAYIIYTSGTTGKPKGVMVEHR
GIVNSVLWKKAEYKLTVGDRSLLSLSFAFDAFVLSFFAPVLSGATVVLAQEEEAKDPVAL
KKRIAASRCTLMTGVPSLFQAILECSTSADLRPLQTVTLGGEKITAPLVEKSKQLNPDLV
IVNEYGPTESSVVATSLRIVDTDAAITIGRPIANTSLYIVDKFHQLQPIGVIGEICIGGL
GLARGYWNKPTLTDEKFVPHPFAAGERMYKTGDLGKWLPDGTIEFVGRIDEQVKVRGYRI
EIGEIESVLLAVEKLTAAVVVVHEDQLGQPSLAAYFTATEKLEVAKLWSLLAQRLPSYMI
PAYFVQLDQLPLTPNGKIDKKALPKPEGKPVTGAEYAAPTNAVERKLAEIWERVLGMSGI
GILDNFFQLGGHSLKAMAVAAQVHREYQVELPLKVLFAQPTIKELAQYVATSGKEAYVPI
QPAPLQEYYPVSSAQKRMYVLRQFADTGTVYNMPSALYIEGDLDVERFAAAIDRLVERHE
SLRTSFHTVNGEPVQRVHEHVELHVQYGELTEEQVAPTVASFVQPFDLVKAPLWRVGLFK
LEAKRHLFLMDMHHIISDGVSAGIIVEEFSKLYRGEALPALSVHYKDFALWQSELFQTDV
YRKHEDYWLHAFSGDIPVLDLPADFSRPLAQSFEGDCVSFQADKPLMDALSKLAQENQST
LFMVLLAAYNVLLAKYSGQEDIVVGTPIAGRSHADVENVLGMFVNTLALRNYPAKAKQFQ
AFLEEVKQNTLQAYAHQDYPFEALVEKLDIRRDPSRNPLFDTMFILQNLDQKAYELDGLK
LEAYPAEAGNAKFDLTLEAHEDEAGIHFALVYSTKLFRRESIERIAGHFLQVLREVVADQ
TVALQEISLLDEEERQLVTVDFNNTFADYPRDCTIQELFEQQAAKTPEHAAVVMDGKRLT
YRELNEKANQIAHVLRRHGVEKDGIVGLLADRSPEMIAGILGILKAGGAYLGLDPEHPSE
RLSYMLEDGGVKVVLVQRHLLPLVSEGLIPIVLEAASLDQEDSGNPAIVNGARDLAYVMY
TSGSTGKPKGVMVEHRNVTRLVMHTNYVQVRETDRMVQTGAIGFDAMTFEIFGALLHGAS
LYVVRKDVLLDAEKLGSFLRANQITTMWLTSPLFNQLSQENPAMFDSLRALIVGGEALSP
AHINRVKSALPALEIWNGYGPTENTTFSTCYLIEKHFAEQIPIGKPIANSTAYIVDGNNQ
PQPIGVPGELCVGGDGVARGYLNKPDLTAEKFVPNPFAPGETMYRTGDLARWLADGTIEY
LGRIDQQVKIRGYRIELGEIEAVLSQQDNVKEAVVAVIEEGNGQKALCAYFVPEQAVDAT
ELRDALSKQLPGYMVPAYYVQMEKLPLTANGKVDRRALPQPSGERTAGSAFVAPQTETEA
KLAQIWQTVLGLPAIGIHDNFFEIGGHSLKAMNVITQVHKTFQVELPLQALFASPTIHEL
AAYIAESAFEQFETIPPTEPAAYYPVSFAQNRMYILHQFEGSGISYNVPNVLVLEGKLDY
DRFAAAIQSLVKRHEALRTSFHSVNGEPLQRVHAEVELPIRMIEATDEQAEALVQELIQP
FDLATAPLFRVNLIKLGAERHLFFMDMHHIISDGVSLAVIVEEIASLYEGKQLSDLRIQY
KDFAVWQTKLAQSERFQKQEEFWTRTFADEIPLLNLPADYPRPSVQSFDGDTVALGTGQH
LLEQLRQLASDTGTTLFMVLLASYHVLLSKYAGQEEIVIGTPIAGRSHADVERIVGMFVN
TLALKNTAAGSLSFRAFLADVKQNALHAFEHQDYPFEHLVEKLQVRRDLSRNPLFDTMFS
LGLADAAAGQVAGLKLSPYPVNGHIAKFDLSLDAMEKRDELLVQFSYCTKLFAKETIDRL
AAHFVQLLQTITADPDIRLAEISVLSQAETKRMLEGFLATKRAYPTDKTFPMLFEEQAEK
TPYQIAVVCENEQLTYRELNAKANRLARVLRRKGVKPESTVGILVDRSPYMVIGMLAVLK
AGGAFVPIDPDYPLERQAFMLEDSEAKLLLTLQKMNSQVAFPYETIYLDTERVDQEEADN
LEHVARPEHAAYIIYTSGTTGKPKGVVIEHRSYANVAFAWKDEYHLDSFPVRLLQMASFA
FDVSTGDFARALLTGGQLVICPNEVKMDPASLYEIIRRHEITIFEATPALIMPLMHYIYE
NKLDISQMKLLILGADSCPAEDFKTLLARFGHTMRIINSYGVTEACIDTSYYEETDVTAI
RSGTVPIGKPLPNMTMYVVDAHLNLQPVGVVGELCIGGAGVARGYLNRPELTQEKFVPNP
FAPGERLYRTGDLAKWRADGHVEFLGRNDHQVKIRGVRIELGEIETQLRKLDGIAEAVVV
AREDHRQEKELCAYVVTDHALDAAELRANLLKELPQAMIPSYFVTLDALPLTANGKVDRR
SLPAPDVTMLRTTEYVAPRSVWEDRLARVWEQVLNVPQVGVQDDFFALGGHSLRAMRVIA
SMHNEYQVDIPLRILFEKPTIQELAAFIEETAKGNVFSIEPAQQQAYYPVSSAQKRMYIL
DQFEGVGISYNMPSTMLIEGKLDRTRVEAAFQRLIARHDSLRTSFAVVNGEPVQHIHADV
PFALAYSEVTEDEARKLVSSLVQPFDLGVAPLMRVSLLKIGEDRHVLLTDMHHSISDGVS
SGILLAEWVRLYQGDVLPELRIQYKDFSVWQQAFFQSAAFEKQEAYWLQTFADEIPVLNM
PTDFARPGTQSFAGDQYTLQTGKPLAEGLNQLAQATGTTLYMVLLAAYNVLLSKYAGQED
IVVGTPITGRSHADLEPIVGMFVNTLAMRNKPQREKTFSEFLQEVKQNALDAYGHQDYPF
EELVEKLAISRDLSRNPLFDTVFTFQNSTEEVVALPACTLTPFMTEETGKHAKFDLTLIA
TEEKEEITIGVEYSTSLFTRETIERLSRHFLAIAASIVHNPHIRLGDIDMLSLEEKQQIL
AGFNDTAVNYDLDKTLHQLFEEQVEKTPDQAALLFNGQTLTYRELNERANRLARVLRAKG
IGPDRLVAIMAERSPEMVIGILGILKAGGAYVPIDPGYPQERIQYLLADSQAALLLSQAH
LLPLLARVSNELPECLELNAEQDAGLGGTNLPPVNQPTDLAYVIYTSGTTGKPKGVMIPH
RGIVNCLQWRRDEYGFGPRDRALQVFSFAFDGFVASLFAPLLGGATCVLPREEEAKDPVA
LKKLIGATEVTHYYGVPSLFQAILDCSAATDFPRLRCVTLGGEKLPVQLVQKTKEKHPAI
EINNEYGPTENSVVTTISRSIEAGQAITIGRPLANVHVYIVDDGHHLQPVGVVGELCIGG
AGLARGYWNKPELTAEKFVENPFCPGERMYKTGDLVKWRPDGTIEYIGRADEQVKVRGYR
IEIGEIESAVLAYQGIDQAVVVARDDDAAYGPYLCAYVVAAAEVSVSGLRSHLAKELPAY
MVPSYFVQLEQLPHSANGKVDRKALPKPQQSDATTREYVAPKNATEQQLASIWQEVLGVE
PIGITDDFFELGGHSLKATLLIAKVYAYMQIELPLNLIFQHPTVEKVADFITHKRFETRY
GKAILLNEQTGRNVFCFTPIGAQSVYYQKLAAETHGVSLYSFDFIQEDDRMEQYIEAITA
IDPDGPYTLMGYSSGGNLAFELAKELEKRGHVVTDLILFDSYWKDKAIERTVAETENDIA
QLFAEIGENTEMFNMTEEDFQLYAANEFVKQSFVRKTVSYVMFHNELVNTGMTNAAIHLI
QSELEADEDAPVAAEWNEAAWAKATKRLMTYNGYGIHAHMLAGRYVSQNAAIFQNILQEL
FILK
NT seq 19455 nt   +upstreamnt  +downstreamnt
atgaaaaagcaggaaaacatcgcaaaaatatacccgttaaccccgttgcaagaggggatg
ttgtttcacgcggtcaaagacacgggcagcagcgcctactgcctgcaaatgtcggcgacg
atcgaaggtgattttcacctgcctctttttgaacagagcttgaacaagctcgtggaaaac
tacgaagtattgcgcacggtgtttgtgtaccaaaacttgcagcggccccgccaggttgtg
ttgaaagagagaaaggttgccgttgctttcgaaaacatcgcgcatttgccaacgtttgag
cagaacgagtacataacggcgtacaaaaatcagcaccatacgtttgacctgacaaaagac
agcctgatgaaagccgccatttttcagacaggcgagaacaagtaccagtttgtctgggcg
ttccaccacattatcgtggacggttggacattgggcgtcctgcttcagaagctgctggcg
tactacgcagccctgcgcaacggcgagccgattccgcgggaagcgacgaagccgtacagc
gaatatatcaaatggctggataagcaaaacaaggaagcggcgctcacctattggcaaaac
tatttggcaggctacgaccatcaggccgattttccgaaaaagaagcacagcgcggaagct
ggccgctacgaacacgtcgagtcgatgtttgcgatcgctcccgaacagacgcagcaactg
atgcagatcgccaatcaaaaccaggcgacgatgagcagcgtattccaggcactctggggc
attttggcgagcaagtacaaaaatgcggacgatgtcgttttcggctcggtcgtctccggc
cgtccgccgcaaattccgggaattgagagcatggtgggcctgttcatcaacacgattcct
acccgcgtccagacgaacaggcaacaatcgttcagcgagctgctccaaacggtgcaaaag
caagcgttggcttcggcagcctacgatttcgcgccgctgtacgaaattcagagcacgacc
gtactgaaacaagcgttgatcgatcatttggtcacgtttgaaaactacccggaccattcg
atgaaacatttggaagattcgttagggttccagctcaccgtggaaagcggggaagagcag
acctcctacgatttgaacgtagtggtagccctcgctccgtcaaacgagctgtacgtgaag
ctaagctacaatgccgccgtctacgagccgtcttttgtcaaccgaatcgaggggcatttg
agaacggtcatcgagcaggtgattcgcaatccgcacgtgcggctgcacgagatcggcatc
atcaccgaggaagaaaaacagcaactgctcgtcgcctacaacgacacggctgctgactac
ccgcgggacaagacgatttttgcattgatcgcagagcaggcgacccggaccccgacgaaa
atcgcggctgtatgcggcgatgacagcctgacctatcaggagctgatggagcgctcggcc
cagcttgccaaagctttgcgcgacagaggcattggcaggggcagcatcgtttcgattatg
gcggagcattcgctggagctgatcgtagcaatcatggcggtcctgcaatcaggtggcgct
tacttgccgattgatcccgaatatccgctcgatcgcatccagtatttgctcgacgacagc
cagacgacgattcttttcacccagtcgcatctgcagccaaacatccagtttgcaggcagc
attctttatctggacgatccttccttgtatgcgggcgacagcacaccattcgcagccgag
agcaagcccgacgatttggcttacatgatctacacctccggctctacaggcaacccaaaa
ggggcgatgattacccatcaaggcttggtcaactacatttggtgggccaacaaagtgtac
gttcaaggggaagccgtggactttccgctgtactcatccatttcgtttgacttgactgtc
acgtcgatcttcacgccgcttctatcaggcaacacgatctatgtgtacagaggggcagac
aaggtacagctcattttggacatcatccgcgacaacaaagtggggatcatcaagctgacg
ccgacgcacctgaagctgattgaagacgtagacggcaaggcgagcagcatcagacggttc
atcgtcggcggcgagaacttgccgacaaagctggcgaagcaaatttacgaccacttcggc
caggacgtgcaaattttcaatgaatacggaccgaccgagacggttgtcggctgcatgatt
tatttgtacgacccgcaaaaaacgacccaggaatcggtcccgatcggggttccggcagac
aacgtccagctttatttgctcgatgcttccatgcaacccgtgcccgtcggctcgctgggc
gaaatgtacatatccggagacggcgtagccaaagggtatttcaacagaccggagctgacc
gaggaaaaatttatcgacaacccgttccgcccgggaacgaaaatgtaccgcacaggcgac
ctggcaaaatggctgcccgacggaaacatggaatacgcaggaagaatcgaccaccaggta
aaaattcgcggacaccggatcgagatgggcgaaatcgaaacgcgtctgacgcagcacgag
tcggtcaaggaagcggtcgtgatcgcggacaaggacgagagcggccaaaatgtgctgtac
gcctatttcgtttccgagcaagagctgaccgtagcggagttgagaacgtttttgggcagt
acgcttccttcttacatgattccttccttctttattcgcttggcggaaattccgttgaca
gcgaatggaaaagttgagcgaaagaaattgccgaagccagacggcgcagtcgttacagga
accgcgtatgtcgctgcgcaaaatgacatcgaggcaaagctggcggaaatttggcagcag
gtgctgggcatgagccaggtagggattcacgacgatttctttgacctgggcgggcactcg
ttgaaggcgatgacggtcatctcccaggtcgcgaaggcgctggaagtcgatttgcctatc
aaagctctgttcgaacacccgaccatagcggagctggcccgcttcctgtcgcagtcggag
aaaagcaagcacactgcgattcagcctgtggaagcgcaagagttttatccggtttcttcc
gcgcaaaaaagaatgtacatcctccagcagttcgaaggaagcggcatcagctataacatt
tcgggcgccatcctgttggaaggaaagctggattacgcccggtttgccagcgcgatccaa
caactggcagagcgccacgaagccttgcgcacctcgtttcaccgcatcgagcctgtgcaa
aaagtgcatgcaaaggtagaagtgccactgttcatgctggagtcgaccgaggacaaggcg
gagaacatcatgcgcgagtttgtccggccgttcgatctcggggtcgctccgctcgtgcga
acaggcttggtcaagctggggacagaccgccacttgttcctgctcgacatgcatcatatc
atttccgacggcgtatcttcgcaaatatggctgcgcgagtttgccgagctgtacaaggga
gcagagttgccgccccttgcgctccaatacaaagatttcgccgcctggcaaaacgagtgg
ttccagacagacgcgtacaagcagcaggagcagcattggctgaacgcgtttgccgatgaa
atcccgctcctgaacttgccgacggactatccgcgcccgagcctgcaaagctttgaaggc
gacctcgtcctgtttgccgccggaaaagagcggctggagcggctgcaacaagtagcggca
gagacagggaccactctgtacatggttttgctcgccgcgtacaatgtgctgctgtccaag
tacacgggccaggaagacatcattgtcggcacccctgtcgctggccgttcccatgtggac
gtggaacagatcatgggaattttcgtgaatacgttggcaatgcgcaaccagccggccagc
agcaaaacgtttgcgcaatttttgcaagaagtgaagcgaaatgcgcttgcggcctatgac
catcaagattatccgtttgaagagctggtggaaaagctggcgatccagcgggatattagc
cgcaatccgctgtttgacacgatgttttctttggaaagcgcgagccagaagacgcttgcc
atcgaccgactgaccgtgtcgccgtatgagttgttcaacaaaatttccaagtttgatctc
gtgttgaatgccagtgaatcgccagcagacattcagttccagctcacattcgccaccagg
ctgttcaagaaagaaacggtgcaaagaatggccgagcattacctggaaattttgcgcgcg
atcagcgagcggccgacagtcaaactggcggacatcgacatgatgacggaagcagaaaaa
cgtgccctcctgctgaacgtgaacgatacgtttgtggagcgcactaccgctatggccttg
catcaattcgtggaggagcaggcggcacgcacgccggatgaagtggctgtcgcgtatgaa
gggcacgccttaacctaccgcgagctgaacgcccgggcgaatcaactggctcgcttgctg
cgcagtcagggaacccgtccgggtacattgatcggtattatggtagaccgctcgccgggg
atggtcgtcgggatgctggccgtgctcaaagctggcggcgcgtacacgccaatcgacccg
agctatccggcagaacgaatccgctacatgctccgcgacagcgaggcgccgatcttgctg
acgcagcgccatttgcaggagacggtggcgtatgcaggggcgatcatcgacgtagacgaa
gaagcgatttacacaggagacgacacgaatctggacaacgtcgctggccaagacgacctg
gcctatgtgatctacacgtcaggatcgacgggaaagccgaagggagtcatgatctcgcac
caggcgatctgcaatcacatgctgtggatgagagagacgttcccgttgacgacggaggat
gccgtcctgcaaaaaacgccgttcagcttcgacgcttctgtatgggaattttacttgccg
ctgatgacgggagcgcggctcgtcctggcgaagccggacgggcatcgcgacatcgcgtac
atgactcgcctgatttgcgaacaaaacattacgactttgcagatggtcccgtccttgctc
gatctagtcatgaccgacccgggttggagcgcatgcacgagcttgcaacgggtgttctgc
ggcggcgaagcgttgacacctgctctcgtctcgcgtttttacgagacgcaacaagcccgg
ttgattaacttgtacggccctacagaagccacgattgacgcgacctactggctttgcccg
cgccagcaggaatacagcgtcattccgatcggcaaaccgattgacaacgtccgcctgtac
gtcgtcaatgcgagcaaccagcttcagcctgtaggcgttgccggggagctgtgcattgcc
ggagacggtttggcccgcggctattggcagcgcgaggagctgacgcaagcaagctttgtc
gacaacccgttcgagccgggcggcaggatgtatcgcactggcgacatggtccgctatttg
ccagacggcgagatcgagtatgtgggccgcatcgatcatcaagtaaaaatcagaggccac
cgcatcgagctgggggaaatcgaagccaagcttttgcagcatgaagcggtcaaagcagcc
gttgtcatcgcccgccaggatggcaacgggcaaaacagcctgtccgcatatgtcgtggca
aagcaggacattcaaacagcggagctgagaacgtacctgtctgccgcattgccagcctac
atggttccgtccgcgtttgttttcttggagcagttgccgctgtcggcgaatggcaaagtg
gatcgccaagcattgccgcagccggaggacgcagcggcagcggattcgatgtatgtagcg
ccacgcaacgaactcgaagcgaagctcgcacaaatgtgggaaagtgtgcttggcgtggag
cggatcggggttcacgatcatttctttgagctgggcggccattccttgaaggcgatgaac
gtcattgctttgattcagcgcaccttccaggcggaagtaccgttgaaagcgttgtttgaa
tcgccgacgatcgccagctttgcccccatcgtcgctgccgccagcaaaggcgcgaacacc
gcgatccagcctgtcgaaaaacaggagtattaccccgtgtccgccgcacagaagagaatg
tacattctccagcaaatggaaggggcaggcatcagctacaacatgcctggtttcctgtac
ctcgacggcaagctggatacagagcggctgcagcaagcgctcaaccgtctggtgcagcgc
cacgaatctttgcgcacctcgttccactccgtgcaaggcgagactgttcagcgcgtgcac
gaggatgtcgagcttgcgatctcgtttggcgaagcgacggaggcagagatccggcaaata
gccgagcggtttatccagccgttcgatctgggaacagccccgctttggcgtgccggactc
atcaagctggcgccggaacgccacctgttcatgctcgatttgcaccacatcgtcgcagat
ggcgtctccatcgggctgctcatccaggaatttgcccggctttatcgcggcgaagagctg
cctgaactgcgcattcagtacaaagattttgccaagtggcagaatgactggttccagacc
gatgagtttgccgcgcaggaagcttactggatcgaccgttttgcggaggacatccctgtt
ctgaacctgccgacggactacccgcggccctcggtcaaaagctttgcgggagatcgcttc
gtctttggctccggcaccgctttgcaaaaagaactgcaccagcttgcgcacaagacaggg
acgacgctctacatggtgttgcttgcggcgtacaatgtgctgttgtccaagtactccggg
caagaggacatcgtcgtcggcgctcctactgccggcaggtcgcatgcagagacaaaatcc
atcgtcgggatgtttgtcaacacactcgccttgcgcaacgagccagccggggacaaagcc
ttccacagctttttggccgaagtgaaagccaacacgctaaaagcgtttgagcatcaggac
tatccgctcgacgagcttgtcgacaagttgaacattcagcgggatttgagccgcaatccg
ttgttcgacaccgtctttattttgcaaaacatggagcaaaagccgtttgcaatggagcga
ctgaccgtgacgccatatgcgacagaggtgaagcaggccaagtttgacctgtcgctcgag
gcgtacgaggaaaacgcggagatcgtctttagcctggactactgcaccaagctgttttcg
cgcgagacgatgaaaaacgtagcggcgcatttcctgcaaatcttgcgggtcgtcgccgcg
aaccccgaggtgctgctgtccgagatcgccatgctgaccgcagaggaaaagcaacgcttg
ctggtcgacttcaacgacacgcacaaggattttccgcaagacaaaacgctttcggcgctg
ttcgaagagcaagcagaaaaaacgccgcaggcgacagccgttgagatcggcgagcagcag
ttgtcctatcgggagttaaacgagcgggccaaccagcttgccgccacgttacgcgagcgg
ggcgtaaagcctgaccaaaccgtagggattatggtcaaccgctctgtggagatggctgtc
ggcatcctcgctattttgaaagcaggcggagcctatgtgccgatcgacccggaatatccg
gaggaacgcatcgcctacatgctcgcggattgcgaagcccggctggtgcttgcgcaaaag
catctgggaccgaagctcggatccggggtgagcgcggaatgcctgtacgtggacgacgag
agcgcctattcggcgcagcgcgcgaatttgcagccgatccataccgcttccgacctggct
tacatcatctatacatcaggtacgaccgggaagccaaaaggggtcatggtcgagcatcgc
ggcattgtcaacagcgtgttatggaaaaaagcggaatacaagctgaccgttggcgacaga
agcttgctgtctctgtcgtttgccttcgatgccttcgtgctgtcgttctttgcgcctgtt
ctgtccggagcaaccgtcgtactggcgcaagaggaagaagccaaagaccctgtcgcgctg
aaaaagcgcattgccgcttcgcgctgcaccctgatgacaggggtgccgagcttgttccag
gctattttggaatgcagtacgtcggcggatctccgtccgctgcaaaccgtcacgctcggg
ggagaaaaaatcacggctccgctcgttgaaaagagcaagcagttgaatcccgatctcgtt
atcgtcaacgagtacggtccgacggaaagcagtgtcgtcgctacctcgctgcgcatagtc
gatacggatgccgcgatcacgatcggtcggccgatcgccaacaccagcctgtacatcgtc
gacaaattccaccagctacagcccatcggtgtgatcggggaaatttgcatcggcggcctc
ggcttggcgcggggctattggaacaagccgacgctcacggacgagaagttcgttccgcat
ccgtttgcggcaggcgagcgcatgtacaagacgggtgatctcggcaaatggctcccggac
ggcacgattgaatttgtcggtcgcatcgacgaacaggtcaaagtaagaggctaccggatt
gaaatcggcgagatcgagtcggttctgctcgcggtagaaaagctgacagccgctgttgtg
gtcgtccacgaagatcagctcggtcagccgtctctggctgcgtattttactgccacagaa
aagctcgaggtcgccaagctgtggtcgcttctggcgcaaagactgccgtcgtacatgatt
cccgcctattttgtgcagctcgatcagcttccgcttacgccaaacggcaaaatcgacaag
aaagcgttgccgaagccggagggcaagcccgtaaccggagcggaatacgcagcgccaacg
aatgctgtggaacgaaagctggccgagatttgggagcgcgtgctggggatgagcggcatc
ggcattctcgacaactttttccagctcggcggccattccttgaaagcgatggctgtcgct
gcacaggtgcatcgcgagtatcaggttgagcttccgctgaaagtgctctttgcgcagcct
acgatcaaggagttggcccagtatgtcgcgacgagcggaaaagaggcgtatgtgccgatc
cagcctgccccgttgcaggagtattatcccgtttcgtccgcgcaaaagaggatgtacgtc
ctgcgccagtttgcggacacgggcacggtctataacatgccgagcgcattgtacatcgaa
ggcgatctggacgtcgagcggtttgcggctgccattgacaggctggtcgagcggcacgag
tcgcttcgcacctcttttcacaccgtaaatggcgagcctgtccagcgcgtacacgaacat
gtcgagctgcatgtgcagtacggcgaattgacggaagagcaagtggcgccaactgtcgca
tcgtttgtgcaaccgtttgacctggtgaaagcgccgctatggcgggtcggacttttcaag
ctggaggcaaaacggcatctgttcctgatggatatgcatcacatcatctcggacggcgtc
tcggccgggatcatcgtggaggagttctcgaagctgtatcgaggcgaagcgttgccggcg
ctctctgtgcattacaaagatttcgccctctggcagtcggagctgttccaaaccgacgtg
tacaggaagcacgaggactactggctccacgcgttttccggcgacatcccggtgctcgat
ttgccagccgacttttcccgtccattggcccaaagctttgagggggattgcgtttcgttc
caggcagacaaaccactgatggacgcattatccaagctcgcccaggagaaccagtccacg
ttgttcatggtgttgctggccgcttacaacgtgctgctggccaagtacagcggacaagaa
gacatcgtcgtcggaacgccgattgcgggcagatcgcacgccgacgtcgagaacgttttg
gggatgtttgtcaatacgctcgcgttgcgaaactacccggccaaagcgaaacaattccag
gcatttctggaagaggtcaaacaaaatacgctgcaagcgtatgcgcatcaagactatccg
ttcgaagcgctggtcgaaaagctggacatccggcgcgatccgagccgcaatccgctgttt
gacaccatgtttattttgcaaaacctggaccaaaaagcgtacgagctggatgggctgaaa
ctggaagcataccctgccgaggcaggcaacgcgaaattcgatctcacgctggaagcgcac
gaggacgaggcaggcattcattttgcgctcgtctactcgacaaaactgttccgccgggaa
tccatcgaaagaatcgcggggcatttcctgcaagtgctgcgcgaagtcgttgccgatcaa
accgttgccttgcaggagatcagcctgcttgacgaggaagagcggcagcttgtcacggtc
gattttaacaacacgtttgccgactatccgcgcgattgcacgattcaggagctgttcgag
cagcaggcggcaaaaacgcccgagcatgctgccgtcgtgatggacggaaaaaggctgacg
tatcgggagctgaacgaaaaagcaaaccagatcgcccatgtcctgcgtcgacacggcgtc
gaaaaagatggcatcgtcggtctgctcgccgatcgttcgccggagatgattgcaggcatc
ttggggattctcaaagcgggcggcgcctatttgggcctggacccggaacatccgtcagaa
cgcctttcctacatgctcgaagatggcggcgtgaaggtagtccttgtgcagagacacttg
ttgccgctcgtaagcgaaggtttaattccgatcgtgttggaagcggcgagtctagatcag
gaggactccggcaatccggcgattgtcaacggagcgcgggacctggcttacgtgatgtac
acctcaggctcgacaggcaagccaaaaggcgtcatggtcgaacaccgcaacgtcacccga
ctggtcatgcatacgaattacgtgcaagtccgcgaaaccgaccggatggtgcaaacgggc
gcgattggcttcgacgccatgacgtttgagattttcggcgctttgctgcacggggcgagc
ctctatgtggtgcgcaaggacgtccttttggatgccgagaagctgggcagcttcctgcgg
gcgaaccagattacgaccatgtggctgacatcgccgctctttaaccagctctcgcaagaa
aacccggcgatgtttgacagcttgcgcgccttgatcgtcggcggcgaagcgctgtcgcct
gcacacatcaaccgggtaaaaagcgcccttcctgctctggaaatctggaacgggtatggc
ccgaccgaaaacacgaccttctcgacgtgctatttgatcgagaagcattttgccgagcag
attccgattggcaagccaattgcaaactccaccgcgtacatcgtcgacggcaacaatcag
ccgcagccgattggcgtgccgggcgaattgtgcgtcggcggcgacggggtcgcacgaggc
tatttgaacaagccggacttaaccgcggagaagtttgtccctaatccgtttgcgcctggc
gaaacgatgtaccgcacgggagatttggcgaggtggctggcagacgggacgattgagtat
ttgggccggatcgaccagcaagtcaaaattcgcggataccggattgagcttggggagatc
gaggcggtactgtcccagcaggacaacgtaaaagaagcagtcgtggccgtgatcgaggaa
gggaacgggcaaaaagcgctctgcgcctacttcgttccggaacaggcagtcgacgccacc
gagctgagagacgcgctgtccaaacaattgcctggctacatggttcctgcctactatgtg
caaatggaaaagctgccgttgaccgcaaatggaaaggtcgatcgccgggcactgccgcag
ccatctggcgaacggacggcaggaagcgcctttgtcgctccgcaaacggaaaccgaagcg
aagctggcgcagatttggcagacggttttggggcttccagccatcggtattcacgacaac
ttttttgaaatcggcggtcattccttgaaggcgatgaacgtcatcacgcaagtccataaa
acattccaggtagagctgccgctacaagcgctgtttgcctctccgacgatccatgagttg
gcggcctatattgccgagagtgccttcgagcagttcgaaacgatcccgccgacagagcca
gccgcgtattatccggtgtcgtttgcgcaaaatcgaatgtacatcctgcatcagttcgaa
ggaagcgggatcagctacaacgtgccgaacgtgctggtgctggaaggcaagctggattac
gaccgctttgccgctgccatccagagcctggtcaagcggcatgaagctttgcgcacttcg
tttcattcggtaaacggggagccgctgcaacgagtccatgccgaggtcgagctgccaatc
cgcatgatcgaggcgacagacgagcaggcagaagcgctcgtgcaagagttgatccagcca
tttgatcttgcgactgccccgttgttcagggtgaacctgataaagcttggcgcagagcgg
cacttgttcttcatggatatgcaccacattatttccgatggcgtatcgcttgcggtcatc
gtcgaggaaatcgccagtttatacgaaggaaagcagctttctgacctgcgcatccagtac
aaagattttgccgtgtggcaaacgaagctggcccagtctgaacgcttccaaaagcaggag
gaattttggacccggacgtttgccgacgagattccgttattaaatctgcctgctgactac
ccaagaccttccgtgcagagctttgacggcgacacggtagcgcttggcacgggacaacac
ctgctggaacaactgcgtcagctcgctagcgataccggtacgactttgttcatggtgctc
ctggcttcgtaccatgtgctgctctccaagtacgcaggccaggaagagatcgtcatcggc
acaccgattgcaggccgctcgcacgcagatgtagagcgcatcgtcgggatgtttgtcaac
acgctcgccttaaaaaatacggcggcaggcagcctgagcttccgcgcgtttttggcggac
gtgaagcaaaatgcgctccatgccttcgagcatcaagactatccgttcgagcacctggtc
gagaagctgcaagtgcggcgcgatctgagccgaaacccgctgtttgacacgatgttcagc
ctcgggcttgccgacgcagccgcagggcaagtagcgggactgaagctgtcgccgtacccg
gtgaacggccatatcgccaaattcgacctttcgctggatgcgatggaaaaacgagatgag
ctgctggtccaattcagctattgcacgaagttgtttgccaaagaaacgatcgatcggctg
gcggcccatttcgtccagcttttgcagacgatcaccgccgatcccgacatcaggctggcc
gagatcagcgtgctgtcccaggcggagacgaagcgcatgctggagggcttcctcgcaacg
aagagagcttatccaacggacaaaacgttcccgatgctgttcgaggagcaagcggaaaaa
acaccgtaccagattgcggtcgtgtgcgaaaacgaacaactgacctatcgcgagttgaat
gcaaaagcaaaccggctcgcccgcgtcctgcggcgaaaaggcgtcaagccggagagcacc
gtcggcatcctcgtagaccgctcgccctacatggtcatcggcatgctggccgttttgaaa
gcaggcggggcattcgtcccgattgatccggactatccgctggagcgccaagcgttcatg
ctcgaagacagcgaggcgaagctgctgctcactttgcaaaaaatgaacagccaagttgcc
ttcccttatgaaaccatttatctggatacagagagagtggaccaggaggaagcagacaat
ctggagcacgttgcgcgtccagagcacgcagcatacatcatttacacttccggtacgaca
ggcaagccaaaaggggtcgtcatcgagcatcgcagctatgccaatgtcgcatttgcctgg
aaggacgagtatcacctggacagcttcccggtacggttgctgcaaatggcgagcttcgcc
tttgacgtctcgacgggcgattttgcccgggcactgctgacaggcgggcagctcgtcatc
tgcccgaacgaggtcaagatggaccctgcttcgctgtacgagattatcaggcgccacgaa
atcaccattttcgaagcgacacccgccctgattatgccgttgatgcactacatttacgaa
aacaagctggacatcagccagatgaagctgttgattctcggagcggacagttgtccggca
gaagacttcaaaacgttgcttgcgcgcttcggccacacgatgcgcattatcaacagctac
ggcgtgacagaggcgtgcatcgacaccagctactacgaagaaacagacgtcaccgccatc
cgctcgggaacggtgccgatcggcaaaccgcttccgaacatgacgatgtacgtagtcgat
gcgcatttgaatttgcagcctgtcggggtcgtgggcgaattgtgcatcggcggagcgggc
gtggcgcgcggctacttgaacaggccggagttgacgcaagaaaagttcgtgccgaacccg
tttgccccaggtgaacgactgtaccgcacaggtgatctcgcgaagtggcgcgcagacggc
catgtcgagttcctcggacgcaatgaccaccaggtaaaaatcaggggcgtccgcatcgag
ctgggcgaaatcgagacacaactgcgcaagctggacggaatcgcggaagcagtcgtggtc
gcaagagaagaccacaggcaggaaaaggaattatgcgcatacgtcgtgacggaccatgcg
cttgacgccgcagagttacgggcgaatttgctgaaggagctgccgcaagcgatgattcca
tcgtatttcgtaaccttggacgcgctgccgctgactgccaatggcaaagtagacagacgc
tccttgccagcgccggatgtcaccatgctgcgaacgaccgaatacgtcgcgccgcgctct
gtatgggaagaccgactggcccgcgtatgggagcaggtgctaaacgttccgcaagtgggc
gtgcaagacgactttttcgcgctcggcggccactccctgcgtgccatgcgggtgatagcg
agcatgcacaacgaataccaggtcgatattccgctccgcatcttgttcgagaaaccgacg
attcaggaattggcggcgttcatcgaagagactgccaaagggaacgttttctcgatcgag
ccagcgcaacagcaagcgtactacccggtttcttcggcgcaaaagcgcatgtacattctc
gatcaatttgaaggagtcggcatcagctacaacatgccgtcgaccatgctgatcgaaggc
aagctggaccgaacacgggtggaagcggcgttccagcgcctgattgcgcgccatgacagc
ttgcgcacttcgtttgccgtcgtcaacggagagcctgtgcaacacattcacgcggacgtt
ccttttgcgcttgcctattcggaagttacagaagacgaagcgcgcaaactcgtttcttcc
ctcgtgcagccgttcgatctcggggtcgcaccgctcatgcgcgtctcgcttttgaaaatc
ggcgaggatcgtcacgtgctactcaccgatatgcatcacagcatttccgatggcgtgtcc
tccggcattttgctggccgagtgggtgcggttgtatcagggtgacgttttgccggagctg
cgcatccagtacaaagacttctccgtgtggcagcaggcgtttttccaatcggctgccttc
gagaagcaggaagcgtactggctccagacgtttgccgatgagattcccgtgctgaacatg
ccgacggatttcgcccgccccggcacccagagctttgccggggatcagtacacgcttcaa
acgggcaaaccgctcgcggaaggcttgaaccaactggcgcaagcgacgggaacgaccttg
tacatggttttgctcgccgcgtacaacgtgctgctctccaagtatgcggggcaggaggac
atcgtcgtcggcacgccgattacaggcagatcccatgccgatctggaaccgatcgtcggc
atgttcgtgaacacgttggcgatgcgaaacaagccgcagcgcgaaaaaacgttcagcgaa
tttttgcaggaagtcaaacaaaatgcgctggatgcgtacggccaccaggattacccgttt
gaagagctggtggaaaagctcgcgatttcgcgcgacttgagccgaaatccgctgtttgac
accgtgtttacgttccaaaacagcacagaagaggtcgtggcgctgcctgcatgcacgctt
acgccgttcatgaccgaagaaacaggcaagcacgcgaagttcgacctgacgctgatcgcc
acggaggagaaagaagaaattacgattggcgtagagtacagcacaagcttgttcacgcgc
gaaacgatcgaacggctaagtcgccacttcctggcgattgccgcgagcatcgtgcacaat
ccgcacatccgcctgggcgatatcgacatgctctcgcttgaagaaaaacagcagattttg
gccgggttcaacgacacagccgtcaactatgacctggacaaaacgctgcaccagctattc
gaagagcaggtcgagaagacaccggatcaggccgcgcttctctttaacgggcaaacgctg
acctaccgcgagctgaacgagcgagcaaacagactggcaagggtactgcgcgcaaaagga
atcgggccggaccggcttgtggcgatcatggcggagcgttcaccggaaatggtgatcggc
attctcggcattttgaaggcaggcggcgcctacgtgccgatcgaccccggctatccgcag
gaacgcatccagtacttgctagcagacagccaagcagccttgctgctcagccaagcccat
ctgctgccgctgttggcccgcgtgtccaacgagctgccggagtgccttgagctgaacgct
gaacaggatgccgggcttggcggaaccaatctgccgcccgtcaaccagccgactgatctt
gcctatgtcatttacacgtccggtacgactggcaagccgaagggcgtgatgatcccgcat
cggggaatcgtcaattgcttgcagtggagaagggatgaatacggcttcgggccgcgcgac
agagccttgcaagtattctcttttgccttcgacggctttgtcgccagcttgttcgctccg
cttctcggtggagcaacgtgcgtgctgccgcgagaggaagaagccaaagacccggtcgcg
ttgaaaaagctgatcggcgcaacggaagtcacccactactacggcgtgccgagtctgttc
caggcgattctcgattgctcggcggcaaccgacttcccgcgcctgcgctgcgtcacgctg
ggcggcgagaagctgcctgtacagcttgtgcaaaaaacaaaagaaaagcacccggcaatc
gaaatcaacaatgaatacgggccgaccgaaaacagcgtcgtgaccaccatctcccgttcg
attgaagcggggcaagcgatcacgattggccgaccgcttgcgaacgtacacgtctacatc
gtggacgacgggcatcacctgcagccggttggcgtggtcggcgagctatgcatcggcgga
gccgggcttgcccgcggctattggaacaagccggagctgaccgcagagaagtttgtcgaa
aatccgttttgcccgggcgagcgcatgtacaaaacaggcgacctggtgaaatggcggcca
gacggcacgattgaatacatcggccgtgcagacgaacaggtcaaggtgcgagggtatcgc
atcgaaatcggggagatcgagagtgccgtcctcgcttaccaaggcatcgatcaagcagtc
gtcgtcgcccgtgacgatgacgccgcttatggcccatacctttgcgcctatgtcgtcgcc
gcagcagaagtgtccgtatccggcttgcgaagccatctggccaaagagctgcctgcttac
atggtgccgagctatttcgtccaactggagcaactgccgcactccgcaaacggaaaagta
gatcgcaaagcattgccgaaaccgcaacagtcggatgcgactacacgcgagtacgtggcg
ccgaaaaatgcgaccgaacagcaactggcatccatttggcaagaagtattgggcgtagag
ccaatcggcatcacggacgatttctttgaactgggcggccattccttaaaagctacgctg
ttgattgccaaagtgtatgcgtacatgcagatcgagctgccgctgaacctcatcttccaa
catccgacggtagaaaaggtagccgatttcatcacgcacaaacgctttgaaacgcggtac
ggcaaagccattttgctgaatgagcaaacgggcagaaacgtcttctgcttcacgccaatc
ggggcccagagcgtgtattaccagaagcttgccgcagaaactcacggtgtctccctgtac
agctttgatttcatccaggaagacgaccggatggagcagtatatcgaggcgatcaccgcg
attgatccagacgggccgtacacgctcatgggctattcctccggaggcaatctggccttt
gagcttgcaaaagaactggagaaacgcggccatgtcgtaaccgatctcatcctgttcgac
tcgtactggaaagacaaggcgatcgagcggactgtcgcggaaacggaaaacgacattgcc
cagttgttcgctgagatcggcgaaaacaccgagatgttcaacatgaccgaagaagatttc
caactgtacgcggccaacgagtttgtgaagcaaagcttcgtccgcaaaacggtcagctat
gtcatgttccataacgaactggtgaacaccggaatgacgaatgccgcgatccacctcatc
caatcggagctggaggcggacgaggacgctccggtggcagccgaatggaacgaagctgcc
tgggcaaaagcgacgaaacggctgatgacgtacaacgggtacggcatccacgcgcatatg
ttggcaggccgctacgtgtcgcaaaatgccgcgatcttccaaaacatcctgcaggaactg
ttcatcctgaaataa

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