Bacillus sp. SB49: M662_06360
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Entry
M662_06360 CDS
T10339
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
basb Bacillus sp. SB49
Pathway
basb00290
Valine, leucine and isoleucine biosynthesis
basb00620
Pyruvate metabolism
basb01100
Metabolic pathways
basb01110
Biosynthesis of secondary metabolites
basb01210
2-Oxocarboxylic acid metabolism
basb01230
Biosynthesis of amino acids
Module
basb_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
basb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
M662_06360
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
M662_06360
Enzymes [BR:
basb01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
M662_06360
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Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
EFhand_Ca_insen
Motif
Other DBs
NCBI-ProteinID:
QHT46128
UniProt:
A0A7Z2Y9V7
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Position
1223544..1225091
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AA seq
515 aa
AA seq
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MARVKVFDTTLRDGEQSPGVNLNRLEKLEIAKQLERLGVDIMEAGFPASSQADFDSVKEI
ADTIRGCSVTGLARANKKDIDIAWEALKGGAEPRLHVFIATSPIHMTHKLKKTPDEVVEK
AVEMVAYAKERFPHVQFSAEDALRSDRDFLVHIIEKVIDAGASVINLPDTVGYTTPDEIG
SLFRYVQENVPNINQAVLSTHNHDDLGMAVSNSLAAIENGARQIEGTINGIGERAGNAAL
EEIAVALQIRKDRFDLETGLVLKEIKRTSELVSRLTGMMVPGNKAVVGRNAFAHESGIHQ
DGMLKESSTYEIITPEMVGVEATNMVLGKHSGRHAFKQKAEELGFELNETKLQEAFESFK
TLTGKKKEVTDADLFAILIDTQTEHADQPKYELKAFQVQYGSINRPTATVLLTTPEGKEV
EKANTGEGSVEAIYNTLDDLIEADVHLEDYQLSSVGRGRDALAEVHVQVSVDGVTASGRG
SAQDVLEASAHAFLNAVNRTLYQRKRSADYEQIQV
NT seq
1548 nt
NT seq
+upstream
nt +downstream
nt
atggctcgcgttaaggttttcgatacgacgcttagggatggagaacagtccccgggtgtc
aacttgaaccgtttggagaagttggaaatcgccaagcagttggaacgtctgggtgtggat
atcatggaagcaggtttccctgcttcctcccaggcggactttgattcagtcaaagagatt
gctgatacgatccgcggttgttcggtcaccggacttgcaagagcgaataaaaaggatatt
gatatcgcgtgggaagccttaaaaggaggcgcggagccccgtcttcacgttttcatcgcg
acatccccgattcatatgacacacaagttgaaaaagacgccggatgaagtcgtcgagaaa
gcggtggaaatggtcgcttatgcgaaggagagattcccgcatgtccagttctccgcagag
gatgctttacggtccgatcgtgatttcctcgtccatatcatcgagaaagtgatcgatgcc
ggggcgagcgtcatcaaccttccggatacggttggttatacgaccccggatgaaatcggc
agcctgttccgctacgtacaggagaacgttccgaatataaatcaagcagtcttgtccacg
cacaaccatgacgaccttggtatggccgtcagtaattccctggcagccatcgaaaacgga
gcccgccaaattgaagggacgatcaacggaatcggggaacgggccggcaacgccgctctg
gaagaaatcgccgtcgctcttcagatcaggaaagatcgttttgatttggagacaggtctt
gtattgaaggagatcaagcgtacgagtgaacttgtcagccgtttgacagggatgatggtt
cccgggaataaggcggttgttggacgtaacgccttcgcgcatgagtccggcatccaccag
gacggtatgctgaaggagtcctccacttatgaaattattacaccggaaatggtcggtgtg
gaagcaacaaacatggtgcttggtaaacactccggccgccacgcttttaaacaaaaggca
gaagagctcggctttgagttgaatgaaacgaagcttcaggaagcgttcgaatcgttcaag
acgttgacaggcaagaagaaagaggtcacggatgcggatttgtttgcgattctgatcgat
acgcagacagagcatgcggaccagccgaaatacgaactgaaggcattccaagtccaatat
ggaagcatcaatcgtccgactgctacggttctcctgacgacgccggaaggtaaggaagtg
gagaaggcaaacacgggagagggaagtgtagaagcgatttataatacgctcgacgatctg
atcgaagcggacgtacatctcgaggactaccagctcagctctgtcggaagagggcgggat
gctcttgcagaggtccacgtccaagtatccgtcgacggggtgacggcatccggacgcggc
tcggcgcaggatgtgctggaagcatccgctcatgctttcttgaacgcagtgaaccgaaca
ctttaccagcggaaacgttctgctgattatgaacaaatccaagtatga
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