Microvenator marinus: FRD01_13170
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Entry
FRD01_13170 CDS
T08125
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
bbae
Microvenator marinus
Pathway
bbae00260
Glycine, serine and threonine metabolism
bbae00261
Monobactam biosynthesis
bbae00270
Cysteine and methionine metabolism
bbae00300
Lysine biosynthesis
bbae01100
Metabolic pathways
bbae01110
Biosynthesis of secondary metabolites
bbae01120
Microbial metabolism in diverse environments
bbae01230
Biosynthesis of amino acids
Module
bbae_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
bbae_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
bbae00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
FRD01_13170 (thrA)
00270 Cysteine and methionine metabolism
FRD01_13170 (thrA)
00300 Lysine biosynthesis
FRD01_13170 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
FRD01_13170 (thrA)
Enzymes [BR:
bbae01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
FRD01_13170 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
FRD01_13170 (thrA)
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GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_7
NAD_binding_3
ACT
PAC2
Motif
Other DBs
NCBI-ProteinID:
QED28164
UniProt:
A0A5B8XRI9
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Position
3202018..3204483
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AA seq
821 aa
AA seq
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MWHVHKFGGTSVANAARYRGVLKIVTEELAQRSGGKSAVVVSAMAGVTNALIELVELSAR
QDPSYATALRSLRLKHHECVADLLGADGQALIDTLNQDFDDIEDVLRAIWLLKSAPTHAL
DLISGYGEIWSAQLLAAALKAAGADVTWLNARDVLVVEPGQLAPIVDWAQTQAAMDAFLS
ENPSEIVVITGFVATSRDGIATTLGRNGSDYSAAIFGALLQAQEIVIWTDVDGVMSANPR
LVPDAIVLESMSYHEAMELAYFGAKVIHPSTMAPAVARSIPLYIKNTFAPEKPGTRIHTA
SDPRFAVKGIATVDQMALINVEGTSMIGVPGIASRLFGALREADVNVVMISQGSSEHSIC
FAVPEKDTKAARAAVEQAFFAELHHGQIQTIDVVTPCTVLAVVGDHMAGIPGIAAKFFGA
LGNAGVNIRAVAQGSSERNISVVIDTANAQRALRAVHSGFYLSNQTISVGIIGPGVVGAT
LIKQLAAEQARLSRDYQIDLRVRGIADSKKMLLHDTNIELGSWEEGFSAGLESNLDTFAA
HVASDGFPHAVIIDCTASEAVARHYLGWLEKGVHVVTPNKKANSVEFDYYQALKTTCRKR
QRHYLYETTVGAGLPIIQTLHDLIQTGDKVQRIEGILSGTLAYLFNAFDGSTPFSNIVRD
AKTKGYTEPDPRDDLSGTDVARKLVILAREMGLTINLEDVEIESLVPEHLQDVSVAEFLE
RLSDVDDAMLAKLKTAKENGAVLRFVGQVDQTGKASVKLSEYADTHPFARIQLTDNIVQF
TTARYSQNPLVVQGPGAGPEVTAAGAFGDLLRLANYLGAPL
NT seq
2466 nt
NT seq
+upstream
nt +downstream
nt
atgtggcacgtacataaatttggcggaacgagtgtggcgaacgccgcgcgatatcgcggt
gttctgaagattgtgaccgaggagctggcgcagcgcagcggcggcaagagcgcggtggtg
gtctcggccatggccggcgtgacgaacgcgttgatcgagctcgttgagctcagcgcgcgg
caagacccgtcttacgccacggcgttgcggagcctgaggctcaagcaccatgagtgtgtg
gcggacctgctcggcgccgatggtcaggcgctcatcgataccctgaaccaggactttgac
gatatcgaggacgtgctgcgagcgatttggctcctcaagagcgcgcctacgcacgcgctg
gacctgatttcggggtacggcgagatttggtcggcgcagctcttggcagcggcgctgaag
gctgctggggccgatgtgacgtggctcaacgcccgtgacgtgctggttgtggagcccgga
cagctcgcaccgatcgtggactgggcccagactcaagccgcaatggacgcgtttttgagc
gagaatccgagcgagatcgtggtgattacggggttcgttgccacgagccgcgacggcatc
gccaccacgctggggcgaaacggctcggactactcggccgcgatctttggcgcacttttg
caggctcaggagattgtgatctggaccgatgtggacggcgtgatgtcggcgaatccgcgc
cttgttccggatgccattgtcctggagtcgatgtcgtatcacgaggcgatggagcttgcg
tattttggggcgaaggtgattcacccgagcaccatggcacctgccgtggcacgttccata
ccgctctacatcaaaaatacgttcgcacctgagaagcccggcacccgcattcatacggcc
tctgacccgcggtttgcggtcaaaggcatcgctaccgtggaccagatggcgctcatcaac
gtggagggcacgtccatgattggggtaccaggtatcgcgagccgactcttcggcgcgctg
cgcgaggccgacgttaacgtggttatgatttcacagggaagctccgagcattccatctgt
tttgcggtgcccgagaaggacacaaaggcggcgcgtgcggcggtggaacaggctttcttc
gccgagcttcatcacggccaaatccagaccattgacgtagtcacaccttgcaccgtgctc
gccgttgtgggcgaccatatggctgggattccgggcattgcggcgaagttctttggcgca
ctcggtaacgccggggtcaatatccgtgcggttgcgcagggctcgtcggagcgaaatatc
tccgtggtcatcgataccgcaaacgcgcaacgtgcgctgcgcgcggtgcattcgggattc
tacctttcgaaccagacgatcagcgtggggattatcgggcctggcgtagtgggtgcgacg
ctcatcaagcagctcgcggccgagcaggcgcggcttagtcgggactatcagatcgacctc
agagtgcgcggtattgcggactccaagaagatgcttttgcacgataccaacattgaactg
gggagctgggaagaagggttttcggcggggcttgagtcgaatctggacacctttgcggcg
cacgtcgcgtcggatgggtttcctcatgccgtgatcatcgactgtacggctagtgaagcg
gtcgcgagacattaccttggttggctcgagaaaggcgtgcatgtggtcacgcccaataag
aaggcgaattcggtagagttcgactactatcaggcgctgaagacgacgtgcagaaaacga
caacgccattacctttatgagaccacggtcggcgcggggttgcctatcattcagaccctt
cacgacctgattcaaacgggcgataaggtccaaaggattgaagggattttgtccggtacc
ctggcttatctttttaacgcgtttgatggatcgaccccgttctcgaatatcgttcgggat
gccaagacgaagggctataccgagcctgatccaagggatgacctttcgggcaccgacgtg
gcgcgaaagctcgtcatccttgcgcgcgagatgggtttgacgatcaacttggaagatgta
gagatcgagtctttggtccccgagcacctgcaagacgtgagtgtggcggaattcttggag
cggctgagcgacgtggatgatgccatgcttgcaaagctaaaaacggcgaaggaaaacgga
gctgttttgagatttgtgggccaagtggaccagactggaaaggcgagtgtgaagttgtct
gagtacgcggacacgcatccgtttgcgcggattcagttaacagacaatatcgtgcagttt
acgacggctcgctacagtcaaaaccctctggttgtgcaaggccctggtgccggccctgaa
gtcacggcagcgggcgcgtttggggaccttttgaggttggccaattatctcggggccccg
ctatga
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