Beijerinckiaceae bacterium MG08: CU048_13385
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Entry
CU048_13385 CDS
T10676
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
bbai Beijerinckiaceae bacterium MG08
Pathway
bbai00300
Lysine biosynthesis
bbai00550
Peptidoglycan biosynthesis
bbai01100
Metabolic pathways
bbai01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
bbai00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
CU048_13385
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
CU048_13385
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
CU048_13385
Enzymes [BR:
bbai01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
CU048_13385
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
QBR72094
UniProt:
A0A4P7F7X4
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Position
2812165..2813622
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AA seq
485 aa
AA seq
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MSEVATDETIWTSLGLVSPLDARVSGTLPRGGATGISIDTRTLKKGDLFFAINGVGSDGH
DYVEAAFAKGALAAVVDEAHSGALSSLGPLYVVHEVLPALERLGLAARDRSSARIVAVTG
SVGKTSTKEALRLVLGQAGPTHASVASYNNHWGVPLTLARMPKSTRFGVFEIGMNHKGEI
LPLVGMVRPHIAIITTVAPVHLEYFESIDDIADAKAEIFSGLEPGGVAILHRDIPQYERL
LAHAKASSAGYVASFGEYSGADAKLVSVKLAADHSIVKAEVCGRLLTYRIGAAGRHLAVN
SLAVLLAAKALGVDLEAAAAALASFSAQPGRGERLQLSTEDGPYTLIDESYNANPASMRA
AVALVGALPLPGKGRRIAILGDMLELGENGGTMHAELADELAAHHIDLVFAAGPLMKHLY
DALPQKLKGAWRDHASDLVPIVGAAVQSGDMVIVKGSNGIRMRAIVDALKQNAGTGHPAQ
TGQEG
NT seq
1458 nt
NT seq
+upstream
nt +downstream
nt
atgagcgaagttgccaccgatgaaaccatatggacaagtcttggacttgtgtcgccgctg
gacgcgcgggtgagcggaactctgccacgcggtggcgcgacgggaatttcaatcgatacc
cgcacgctgaaaaagggggatctcttttttgcaatcaacggggtcggttcggacggccat
gattacgtcgaggcggcatttgccaagggtgcccttgccgcggttgtcgatgaggcccat
tccggagccctgtcttcgctcgggccactctacgttgtccatgaggttctccccgcgctc
gaacggcttgggctcgccgcccgcgatcgttcgtcggcccgtatcgtcgctgtgaccggt
tcggtcggcaagacctcgaccaaggaggccttgcggctggtgcttgggcaagcggggcca
acgcatgcctcggtcgcttcctataataatcattggggagtgccgctcactttagcgcgg
atgccgaagagcacaaggttcggtgtttttgaaatcggcatgaaccataagggcgaaatc
ctgcccctcgttgggatggtgcggccgcatattgccatcatcacgacggttgctcccgtt
catctcgaatatttcgaaagcatcgacgacatagccgacgccaaggccgagattttctcg
ggtctcgagcctgggggtgtcgcgatcctgcatcgtgatatcccccagtacgagcgcctc
cttgcgcatgccaaggcttcaagcgctggctatgtcgcaagcttcggcgaatattcgggt
gccgacgccaaattggtgagcgtgaagcttgccgccgatcattccatcgtcaaggcggaa
gtctgcggccgtttgctgacctatcgtatcggcgcggcgggacgccaccttgcggtgaat
tcgctcgcggttttgcttgctgcgaaagctctcggcgtcgatctcgaagcggccgctgcc
gcgctcgcgtctttctcggcgcagccggggcggggcgaacggctacagctctccaccgag
gacggcccgtatacactcattgacgaaagctataacgcaaaccccgcgtccatgcgcgca
gccgtcgctttggtcggcgcccttcctttgccgggaaagggacgccgcattgcaatcctc
ggcgacatgcttgaacttggagaaaatggcggcacgatgcacgcggaacttgccgatgaa
cttgcggcccatcacatcgatctcgtctttgcggccggccctttgatgaaacacctctac
gatgccttgccccaaaaattaaaaggggcgtggcgtgaccacgccagtgaccttgtgccg
attgtcggcgcggcggttcaaagcggcgacatggtgatcgtcaagggctctaatggcatt
cgaatgcgcgcgatcgtcgatgctctcaagcaaaacgccggtaccggtcacccggcgcaa
accggtcaggaaggttga
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