Bifidobacterium animalis subsp. lactis BB-12: BIF_01494
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Entry
BIF_01494 CDS
T01840
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
bbb
Bifidobacterium animalis subsp. lactis BB-12
Pathway
bbb00290
Valine, leucine and isoleucine biosynthesis
bbb00620
Pyruvate metabolism
bbb01100
Metabolic pathways
bbb01110
Biosynthesis of secondary metabolites
bbb01210
2-Oxocarboxylic acid metabolism
bbb01230
Biosynthesis of amino acids
Module
bbb_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
bbb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
BIF_01494 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
BIF_01494 (leuA)
Enzymes [BR:
bbb01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
BIF_01494 (leuA)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
ADC85241
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Position
252282..254195
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AA seq
637 aa
AA seq
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MGQGQSSVFDLAAVAAASNGGNNDPLLPPARYIGAPQKPSDMPYTKYVAYDKQVPFDYPE
RTWPGKRLHRAPRWCSVDLRDGNQALVNPMDSERKLRFWTMLVDMGFKEIEVGFPSASET
DYDFIRLLIERELIPDDVTIVVLTQAREHLIRKTYECLRGCKRAIVHFYNSVSVLQREVV
FRKDRAGIKKLATDAAHLCKELEGDAEGIDLYYEYSPESFTGTEPEYAVEVCNAVIDVIK
PTPGHPMIINLPATVEMTTPNVFADEVEYVSNNLRDRDAVVLSLHPHNDEGMGVAAAELG
MLAGADRIEGCLLGNGERTGNVDLVTLGLNLLTQGIDPQLDLSDMPGIRKTVEYCNQIKI
SERHPYAGNFVFTAFSGSHQDAIKKGLEAREIAAEMAGVDVENFVWLVPYLPIDPKDIGR
SYEAIIRVNSQSGKGGMAYLLKANHNLDLPKKLQVEFEKVVQQHADATKKEVKDGDIWHL
FKDEYLPVEESGAIEAGEVVADTHDETLDQWGRLKLLKVSMSSGEDGSDTRLTATVLDRG
INVGREPEVTREIEGTGNGPIAAFLDALKSFGVVASVLDYAEHTMGVGSDARAASYVQCE
VGQEDEEKRVVWGVGIDSSIITSSLKAIISAINRSNR
NT seq
1914 nt
NT seq
+upstream
nt +downstream
nt
atgggtcagggtcaatcttcggtgtttgatctcgctgccgttgccgcggcatccaatggg
gggaacaatgacccgctgctgcctccggcacggtacattggcgccccgcagaagccgagc
gatatgccgtacaccaagtatgtggcatacgacaagcaggtgccattcgactacccggag
cgcacatggccgggcaagcggctgcacagggcgccgcgctggtgctcggtggatctgcgc
gacggcaaccaggcactcgtgaacccgatggattccgagcgcaagctgcggttctggacc
atgctcgtcgacatgggattcaaggagatcgaagtcggcttcccgagcgcttcggagacc
gattacgacttcattcgcttgctcatcgagcgcgagctcattcccgacgacgtgacaatc
gtcgtgctcacgcaggcccgtgagcacctcattcgcaagacttacgaatgcctgcgcggt
tgcaagcgcgccattgtacacttctacaactccgtctccgtgctgcagcgcgaggtcgtg
ttccgcaaagaccgcgcgggcatcaagaagctcgccaccgatgccgcgcacctgtgcaag
gaactcgagggcgacgccgagggcatcgacctgtactacgagtattcgccggaatcgttc
actggaaccgagccggagtacgcggtggaggtgtgcaatgcggtgatcgacgtgatcaag
ccgacgcccgggcatccgatgatcatcaatctgcccgcgacggtggagatgaccacgccg
aacgtgttcgcagacgaagtggagtacgtttccaataatctgcgcgaccgcgatgccgtg
gtgctctcgctccacccgcacaacgacgagggcatgggcgtcgccgctgccgaactcggt
atgctcgccggcgcggaccgcatcgaaggctgcctgctcggcaacggcgagcgcaccggc
aacgtcgatctcgtcacgctgggcctgaatctgctcacgcagggcattgacccacagctc
gatctctccgacatgccgggcattcgcaagaccgtcgaatactgcaatcagatcaagatc
tccgagcgccacccgtatgccggcaacttcgtgttcaccgcgttctccggctcgcaccag
gacgcgatcaagaaggggctcgaagcgcgtgagatcgccgcggagatggccggcgtggac
gtggagaacttcgtgtggctcgtgccctacctgccgatcgacccgaaggacatcggccgt
tcgtacgaggcgatcattcgcgtgaactcgcagtcaggcaagggcggcatggcctacctg
ctcaaggcgaatcacaatctcgacctgccgaagaagctgcaggtggaattcgagaaggtg
gtgcagcagcatgccgacgccacgaagaaggaagtcaaggacggcgacatctggcatctg
ttcaaagacgagtacttgcccgtcgaggaatccggcgcgatcgaggccggcgaggtggtc
gccgacacgcatgacgagacgctcgaccagtggggccgtctcaagctgctcaaggtgagc
atgtcgtcgggtgaggacggttccgacacgcgcctgaccgccaccgtgctcgaccgcggc
atcaacgtgggccgcgagcccgaggtgacgcgcgagatcgagggcaccggcaacggcccg
atcgccgcgttcctcgacgcgctcaagagcttcggcgtcgtggcgtccgtgctcgattac
gcggagcatacgatgggcgtcggctcggacgcgcgcgccgcctcctacgtgcagtgcgag
gtcggccaggaagacgaggagaagcgcgtcgtgtggggcgtgggcatcgactcgtcgatc
atcacgagctcgctcaaggcgatcatctcggcgatcaaccgctccaaccgctga
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