Bison bison bison (American bison): 104979826
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Entry
104979826 CDS
T08726
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
bbis
Bison bison bison (American bison)
Pathway
bbis04217
Necroptosis
bbis04380
Osteoclast differentiation
bbis04620
Toll-like receptor signaling pathway
bbis04621
NOD-like receptor signaling pathway
bbis04630
JAK-STAT signaling pathway
bbis04658
Th1 and Th2 cell differentiation
bbis04659
Th17 cell differentiation
bbis05145
Toxoplasmosis
bbis05160
Hepatitis C
bbis05161
Hepatitis B
bbis05162
Measles
bbis05164
Influenza A
bbis05165
Human papillomavirus infection
bbis05167
Kaposi sarcoma-associated herpesvirus infection
bbis05168
Herpes simplex virus 1 infection
bbis05169
Epstein-Barr virus infection
bbis05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
bbis00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
104979826 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
104979826 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
104979826 (TYK2)
04621 NOD-like receptor signaling pathway
104979826 (TYK2)
04658 Th1 and Th2 cell differentiation
104979826 (TYK2)
04659 Th17 cell differentiation
104979826 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
104979826 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
104979826 (TYK2)
05160 Hepatitis C
104979826 (TYK2)
05171 Coronavirus disease - COVID-19
104979826 (TYK2)
05164 Influenza A
104979826 (TYK2)
05162 Measles
104979826 (TYK2)
05168 Herpes simplex virus 1 infection
104979826 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
104979826 (TYK2)
05169 Epstein-Barr virus infection
104979826 (TYK2)
05165 Human papillomavirus infection
104979826 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
104979826 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
bbis01001
]
104979826 (TYK2)
Enzymes [BR:
bbis01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
104979826 (TYK2)
Protein kinases [BR:
bbis01001
]
Non-receptor tyrosine kinases
JAK family [OT]
104979826 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kinase-like
FERM_C_FAK1
Kdo
ABC1
Motif
Other DBs
NCBI-GeneID:
104979826
NCBI-ProteinID:
XP_010826669
Ensembl:
ENSBBBG00000003878
UniProt:
A0A6P3GIS2
LinkDB
All DBs
Position
Unknown
AA seq
1171 aa
AA seq
DB search
MPLCQWRATTRGRKPSGDGAQPMATREGLKVLLHWAGPSGGEPWVTFTEPTLTAEDVCIH
VAHKVGITPPCFNLFALFDAQAQVWLPPNHILDTSRDSSLTLYFRMRFYFRNWHGTNPQE
PAVYRCGPPGAETSSEQAEQGVQLLDPASFEYLFEQGKHEFVNDVASLWELSSEEEIHHF
QNESLGMALLHLCHLALRNGVPLEKVAKKTSFKDCIPRSFRRQMRQHNALTRLRQRSIFR
KFLRAFQPGCLSQQVVMVKYLATLERLAPRFGTERVPVCHLELLSQADGEPCYIRDGGQA
PPDPGSESAAGPPTHEVLVSGTEGIRWRLVPAEGPADGGAGGGSRMPDADPSGKKMKAGE
VGSEPVDRPRESPWSYFCDFQDITHMVLKERHVSIHCQDNKCLELTLPSRAAALSLVSLV
DGYFRLTADSNHYLCHEVAPPRLVMSIQDGIHGPLLEPFVLAKLKPEAGLYLIHWSTSHL
HRLILTVAQRDQLQSPGTKGLRLRKFPIELQAGTVMLEGWGRSFPSVRDLRAALQDCSLR
AGNDCFSLRRCCLPRPGERQPYAVVMESFPSTFPQLSHLGQGTRTNVYEGLLRVGGGGPE
EDKADGEEPPTPPAGDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHVHLAFVHGV
FVHGSENIMVTEYVEHGPLDVWLRRERGRVPLAWKLAVAQQLASALSYLEDKSLVHGNVC
GRNILLARLGLAEGTSPFIKLSDPGVGLSALSREERVERIPWTAPECLSGGANSLSTAAD
KWGFGATLLEICFDGEAPLQGRSPSEKERFYQKQHKLPEPSCPELATLTSQCLTYEPAQR
PSFRTILRDFTQLQPQNLADVLSVSPDSLASDPTVFHKRYLKKIRDLGEGHFGKVSLYCY
DPTNDGTGEMVAVKALKAGCGPQLRTGWRREIDILRTLYHKHIVKYKGCCEDQGEKSIQL
VMEYMPLGSLRDYLPRHNVGLVQLLLFSLQICEGMAYLHTQHYVHRDLAARNVLLDNNRL
VKIGDFGLTKAVPEGHEYYCVREDGDSPVFWYAPECLKECKFYYASDVWSFGVLMYELLT
YCDSSQSPPSKFIELIGLTQGQMTVLRLTELLERGERLPQPEKCPSEIYCLMKDCWKAEA
SFRPTFQNLVPILRSYHEKYQGQAPSVFSVC
NT seq
3516 nt
NT seq
+upstream
nt +downstream
nt
atgcctctgtgccaatggagggccaccaccaggggcaggaagcccagtggggacggagct
cagcccatggccaccagagaaggcctgaaagtgcttctgcactgggctggccccagtggt
ggggagccctgggtcaccttcactgagcccacactgaccgcggaggatgtctgcatccac
gtcgcacacaaagtcggcatcactccaccctgcttcaatctttttgccctcttcgatgcc
caggcccaggtctggctgcctccaaatcacattctggatacctccagggactccagcctg
acgctgtacttccgcatgaggttttatttccgaaactggcatggcacgaatcctcaggag
ccagctgtgtaccgctgcgggcccccaggggccgagacttcctcagaacaggcagagcag
ggggtgcaactcctggaccctgcctcctttgagtacctctttgagcagggcaagcatgaa
tttgtaaatgacgtggcatcactatgggagctatccagcgaggaggagatccaccacttt
cagaatgagagcctgggcatggcccttttgcacctctgccacctcgctctccgcaatggt
gtcccccttgaaaaggtggccaagaagaccagcttcaaggattgcatcccacgctccttc
cggcggcagatgcggcagcacaacgctctgacacggctgcgccaacggagcatcttccgc
aagttcctgcgggccttccagccgggctgcctctcccagcaggtcgtcatggtgaagtac
ctggccacgctcgagcgactggcaccccgctttggcacagagcgtgtgcccgtgtgccac
ctggagctgctgtcccaagccgacggggagccctgctacatccgggacggtgggcaagcc
cctcctgaccccgggtctgagtctgctgccggaccccccacccacgaggtgctggtgtca
ggcacggaaggcatccggtggcggctggtaccggcggaggggcctgctgatggtggtgct
ggtggcggcagcaggatgcctgatgctgacccatctgggaagaaaatgaaggccggggag
gtgggcagcgagccagtggacaggcctcgggagagcccctggtcctacttctgtgacttc
caggacatcacccacatggtgctgaaggaacgccacgtcagcatccattgtcaggacaac
aagtgcctggagctgaccctgccttcccgggccgcggccctgtccttggtgtcgctggtg
gatggctacttccgcctgaccgccgactcaaaccactacctgtgccacgaggtggctcct
ccgcggctggtgatgagcatccaggatggtatccacggccccctgctggagccatttgtg
ctggccaagctgaagcccgaggctggcctctaccttatccactggagcaccagccacctc
caccgcctcatcctcacagtggcccagcgcgaccagctgcagtctccaggcactaagggc
ttgcgcctgcggaagttccctatcgagctccaggccgggacagtcatgctggagggctgg
ggccggtctttccccagcgtgcgggacctgagggctgccctgcaggactgctcgctgcgg
gccggcaacgactgcttttccctgcgtcgctgctgcctgccccggcccggagagaggcag
ccttacgccgttgtcatggagagcttcccctccacgttcccccagctgtcccacttgggc
cagggcacaaggaccaacgtgtatgagggcctcttgcgagtggggggcggaggtcccgag
gaggacaaggcagatggcgaggaaccccccacgccgcccgctggggaccgtgggcaggag
cttcgtgtggtgctcaaggtgctagaccccagtcaccacgacatcgccctggccttctac
gagacagccagcctcatgagccaggtctcccacgtgcacctggccttcgtgcacggcgtc
ttcgtgcacggctccgagaacatcatggtgaccgagtacgtggagcacgggcccctggac
gtatggctgcggcgggagaggggccgcgtgcccctggcctggaagttggcagtggcccag
cagctggccagcgccctcagttacctggaagacaaaagcctggttcatggcaacgtgtgt
ggccggaacatcctgctggcacggctggggctggcggagggcaccagccccttcatcaag
ctgagtgaccccggcgtgggcctgagtgccctctccagggaggagcgggtggagcggatc
ccctggacagcccccgagtgcctgtctggtggagccaacagcctgagcaccgcagccgac
aagtggggctttggtgccaccctcctggagatctgcttcgacggcgaggcccccctgcag
ggccgtagtccctctgagaaagagcgcttctaccagaagcagcacaaactgcctgagccc
tcatgcccagagctggccacactcaccagccagtgcctgacctacgagccagcccagcgg
ccatccttccgcaccatcctgcgtgacttcactcagctacagccccagaatctcgctgat
gtcttgtctgtgagcccggattcactggcttcagatcccacggttttccacaagcgatac
ttgaaaaagatccgggatctgggtgagggtcacttcggaaaggtcagcctgtattgctac
gaccccaccaacgacggcactggtgagatggtagccgtgaaggccctcaaggcaggctgc
ggtccccagctccggacgggctggaggcgagaaatcgacatcctacgcacgctctaccac
aagcacatcgtcaagtacaagggctgctgcgaggaccaaggcgagaagtcgatacagctg
gtcatggaatacatgcccctgggcagcctccgagactacttgccccggcacaatgtcggg
ctggtccagctgctgctcttctccctgcagatctgcgagggtatggcctacctgcacaca
cagcactacgtgcatcgagacctggctgcgcgcaacgtgctgctggacaacaacaggcta
gtcaagatcggggacttcggcctcaccaaggccgtgcccgaaggccacgagtattactgc
gtgcgcgaggatggggacagtcctgtgttctggtatgccccggagtgcctgaaggagtgt
aagttctactatgcatcagacgtctggtcctttggggtcctcatgtatgagctgctgacc
tactgtgactccagccagagccctccctcgaaattcatcgagctcataggcctcacccaa
gggcaaatgactgtgctgaggctcacagagctgctggaacgaggggagaggctgccacaa
ccagagaaatgcccctctgagatctattgcctcatgaaggactgctggaaggcagaggcc
tcattccgcccgaccttccagaacctcgtacccatcctcagatcataccacgagaaatac
caaggccaggccccctcggtgttcagtgtctgctga
DBGET
integrated database retrieval system
