Bison bison bison (American bison): 104979876
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Entry
104979876 CDS
T08726
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
bbis
Bison bison bison (American bison)
Pathway
bbis00310
Lysine degradation
bbis01100
Metabolic pathways
bbis05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
bbis00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
104979876 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
104979876 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
bbis03036
]
104979876 (DOT1L)
Enzymes [BR:
bbis01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
104979876 (DOT1L)
Chromosome and associated proteins [BR:
bbis03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
104979876 (DOT1L)
HMT complexes
Dot1-containing complex
104979876 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DOT1
HALZ
Motif
Other DBs
NCBI-GeneID:
104979876
NCBI-ProteinID:
XP_010826728
UniProt:
A0A6P3G4N3
LinkDB
All DBs
Position
Unknown
AA seq
1708 aa
AA seq
DB search
MLSRHAPDSADKHHDAAHEIIETIRWVCEEIPDLKLAMENYVLIDYDTKSFESMQRLCDK
YNRAIDSIHQLWKGTTQPMKLNTRPSTGLLRHILQQVYNHSVTDPEKLNNYEPFSPEVYG
ETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCKHHYGVEKADIPAKYAET
MDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVVFVNNFAFGPEVDHQLKERF
ANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLKGSVSWTGKPVSYYLHTI
DRTILENYFSSLKNPKLREEQEAARRRQQRENKSNTTTPTKVPESKAAVPADTPVDSGAE
EEKAGTATVKKPSPSKARKKKLNKKGRKMVGRKRGRPKKMSATNPERKPKKTQSSLDLLH
AQTASRAASPLPQDAHRPPHSPFYQLPPSVQRPTPEQLLLAPTPPALHRLLESFRIQYLQ
FLAYTKTPQYKASLQQLLDQEKEKNARLLGAAQQLFGHCQAQKEEIKRLFQQKLDELGVK
ALTYNDLIQAQKEISAHNQQLREQTEQLEKGNWELRSQSLRLLKARCEELKLDWSTLSLE
NLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQELLQLKSCVPPDEALALQLRGKP
EAEPSRLHLELDCARFSLPPFSSLSPELSMNGHAAGYELCSALGRPSPKQNTPQYLASPL
DQEVVPCTPSHSGRPRLEKLSSLALPDYTRLSPAKLVLRRHLSQDHAASGKAAASELHPR
AEHAKENGLPYQSPGITNGIKLSPQDPRPSSPTALQMGEKGPEKGVKERAYASSGEAITS
LPVSIPLSTVQPSKLPVSIPLASVVLPSRAEKARSTPSPGPPARESSSTLEKQVAANTHG
AGGNAAGSKSLALAPTGFAYTGSVAISGALAGSPAPLAPGAEPPALDESSSSGSLFATVG
SRSSTPQHPPLLTQPRTCGSASPAPQLCSSPRLGALGPLPDSGKGDLPCEASFSDPESEA
KRRIVFTISAGASSAKQSPSSKHSPLPSGARGDGCQGHGPDGRKRGRRKRASAGTPSLSS
SVSPKRRALPSVAGLFTQSSGSPLNLNSMVSNINQPLEITAISSPESSLKSSPVPYQDND
QPPVLKKEKPLSQTNGAHYSPLTSDEEPGSEDEPGSARIERKIATISLESKSPPKTLENG
GSLAGRKAPLASEPVNSSKWKSTFSPISDLGLAKAADSPLKAGKGREREPDVKNGHNLFM
AAATAPPAGLLSGPANSEPVLLQNLASLPANQAFLPASSAASLPPANASLSIKLASLPHK
VSRPSLTVHHQPLPGLALAQAAPVNPQASSTGPPAVWVSLGMPPPEQVGQRGSWKVMGLR
LCSHDQEGVAPGPTATMCVVCRSVCPSVALAPDLGQRRAVWDFYLNRETMQGWAGPAARG
PPWDGEDGRGRRTGSTVNQRRADLRRRLAGAQLQPLSHKAPEAAGLGAPLSFPGPRGKEG
GAAESGPFVNKRQLDGLGPKGEGGLPTCGPPDKASTAHSKAGKGREREPDVKNGHNLFMA
AATAPPAGLLSGPGLAPAASSAGGAAPSVQTHRPFLGAFAPGPQFALGPMSLQANLGPSV
LQSLFSSVPAAGLVHVSTAATRLTNSHAMGSFSSGVAGGAVGGRQCPPGHLVPQDPLRDE
LGAARCLRRPPRLLGLTTAVCRFPSRAP
NT seq
5127 nt
NT seq
+upstream
nt +downstream
nt
atgctgagccgtcatgccccagactcggctgacaaacaccacgatgctgctcatgaaatc
atcgagaccatcagatgggtctgtgaagaaatcccggatctcaagcttgctatggagaat
tacgttttaattgactacgataccaaaagctttgagagtatgcagaggctctgtgacaag
tacaaccgggccatcgacagcatccaccagctgtggaagggcaccacacagcccatgaag
ctgaacacacggccatccacggggctcctgcggcacatcctgcagcaggtctacaaccac
tcagtgaccgaccctgagaagctcaacaactacgagcccttctccccagaggtgtatggg
gagacctccttcgacctggtcgcccagatgatcgatgagatcaagatgaccgaagatgac
ctgttcgtggacctgggcagtggagtgggccaggttgtgctgcaggttgccgcggccacc
aactgcaaacatcactacggtgtagagaaagctgacatcccagccaagtacgcggagacc
atggaccgagagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacaca
ctggagaggggggacttcctctcggaggagtggagagaacggattgctaacacaagtgtt
gtatttgtgaataactttgcctttggtcctgaggtggatcaccagctgaaggagcggttt
gcaaacatgaaggaaggtggcagaatcgtgtcctcgaagccctttgcgcctctgaacttc
agaataaacagtagaaacttgagtgacattggcaccatcatgcgcgtcgtggagctgtcg
ccgctaaaaggctcggtgtcatggacggggaagccagtctcctactacctgcacaccatc
gaccgcaccatacttgaaaactatttttctagtctaaaaaatccaaaactcagggaggaa
caagaggcagctcggcgccggcagcagcgggagaacaagagcaacacaaccacgcccacc
aaggtgcccgagagcaaggcagctgtgccggcggacacccccgtggactctggtgctgag
gaggagaaagccgggacggccactgtcaagaagccatctccctccaaggcccggaagaag
aagctgaacaagaagggccggaagatggtgggtcggaagcgtgggcgccccaagaagatg
agtgccaccaaccccgagcgcaagcccaagaagacccagagctcactggacctgctgcac
gcccagaccgcgtcacgagcggcctcccccttgccgcaggacgcgcacaggccacctcac
agcccattctaccagctacctcccagcgtgcagcggcctacccccgagcagctgctgctg
gcacccaccccgcccgcactgcacaggctgctagagtccttcaggattcagtacctacag
ttcctggcatacacgaagacccctcagtacaaggccagcctgcagcagctcctggaccag
gagaaggagaagaatgcccggttgctaggcgcagcgcagcagctatttggccactgccaa
gctcagaaggaggagatcaagaggctcttccagcagaaactggatgagctgggagtgaag
gcgctgacctacaacgacctgatccaagcgcagaaggagatctcggctcacaaccagcag
ttgagggagcagacggagcagctggagaagggcaactgggagctgaggagccagagcctg
aggctgctcaaggcacgatgcgaggagctgaagctggactggtccacgctgtcgctggag
aatctgctgaaggagaagcaggccctgaagagccagatctcagagaagcagaggcactgc
ctggagctgcagatcagcatcgtggagctggagaagagccagcggcagcaggagttgctg
cagctcaagtcctgcgtgccgcctgatgaggcactggctctgcagcttcgtgggaagcca
gaggctgagcctagccggctgcacttggagctggactgcgcccgcttctccctgccgccc
ttcagcagcttgagccccgagctctctatgaatggccacgcagccggctatgagctctgc
agcgcactgggtcggccctcgcccaagcagaacaccccccagtacctggcctccccgcta
gaccaggaggtcgtgccctgcacccctagccacagcggccggccacggctagagaagctg
tccagcctggccctgcctgactacaccaggctatcccctgccaagctggtgctgcggcgc
cacctgagccaggaccacgcggccagtggcaaggcagctgccagtgagctgcacccacga
gccgagcatgccaaggagaatgggctcccttaccagagccctggcatcactaatggcatc
aagctgagcccacaagacccccgaccttcatcccccacggctttacagatgggagagaag
ggccccgagaagggtgtgaaggagcgtgcctacgccagcagtggggaggccatcaccagc
ctgcccgtcagcatcccgctgagcaccgtgcagcccagcaagctgcccgtcagcatcccc
ctggccagcgtggtgctgcccagccgcgccgagaaggcgagaagcacacccagccctggg
ccaccggcccgagagtcctcatccacgctggagaagcaggtggctgctaacacccatggt
gccgggggcaacgctgctgggagcaagagcctcgccctggctcccacaggctttgcatac
actggctcggtggccatcagtggggccctggccggcagcccggcacccctcgcccctgga
gccgagcccccagccctggacgagtcctccagctctggaagcctctttgccaccgtgggg
tcccgcagctccaccccgcagcacccacccctgctgacgcagccacgcacctgtggctcg
gcctcgccggccccccagctctgctccagcccccggcttggcgctctgggcccactcccc
gactctggcaaaggggacctgccctgcgaggccagcttctcagaccctgagagcgaagcc
aaaaggagaatcgtcttcaccatctcggcgggcgccagcagcgccaagcagtcaccttcc
agcaaacacagccctctgccgtcgggtgcccgcggggacggttgccagggccatgggcca
gacggccgcaagcggggccggaggaagcgggcatcggcggggacccccagcctgagctcg
agtgtgtcccccaagcgccgggccttgccatctgtcgctgggcttttcacgcagtcttca
gggtcccccctgaacctcaactccatggtcagcaacatcaaccagcccctggagatcaca
gcaatctcgtcccctgagagctccctaaagagctcacccgtcccctaccaggacaacgac
caaccacccgtgctcaagaaggagaagcccctgagccagaccaatggtgcccactactcc
ccactgacttcggacgaggagccaggctctgaggatgagcccggcagtgccagaattgag
agaaaaattgcaacgatctccttagaaagcaagtctccgccaaaaaccttggaaaatggt
ggcagcctagcaggaaggaaggcgccgctggccagcgagccggtcaacagcagcaagtgg
aagtccaccttctcacccatctccgacctgggcctggccaaggcggccgacagcccgctc
aaggcaggcaagggccgtgagcgcgagcctgacgtcaagaacggccacaacctgttcatg
gccgctgccactgcgccccctgcaggcctcctcagcggcccagctaactctgagcccgtg
cttctgcagaacctcgcatccctccctgctaaccaagctttcttacccgcctcctctgcc
gcctctctgccgcctgctaacgcctctctgtccatcaagctcgcctccctcccacacaag
gtgtcccggccctccttgacggtgcaccaccagcccctgcctgggctggccctggcccag
gccgcgcccgtgaacccacaggccagctccacggggccgcccgccgtgtgggtttccctt
ggcatgccgcctccagaacaggtgggccagcggggctcctggaaggtcatggggctaagg
ctgtgctcccatgaccaggagggtgtggctccggggcccaccgccaccatgtgcgtcgtc
tgtcggtccgtctgtccgtcggtggctctggctcccgacctggggcagcgccgggccgtg
tgggatttctacctcaaccgcgagactatgcaagggtgggctgggccggcggcgcggggc
cccccatgggacggcgaggacggacgaggccggagaacaggctctactgtgaatcagcgc
cgcgcagacctgcggagacggctcgctggggcccagctccagcctctctcccacaaggcc
cccgaggcagctggcctgggtgcccccctgagcttccccggcccacggggcaaagagggt
ggcgctgcagagtctggccccttcgtgaacaagcggcagctggacggactgggcccaaaa
ggcgaggggggccttcccacatgcggacccccggacaaggcctccacagcgcatagcaag
gcaggcaagggccgcgagcgcgagcctgacgtcaagaacggccacaacctgttcatggcc
gctgccactgcgccccctgcaggcctcctcagcggcccaggtcttgccccagcggcatcc
tcggcaggtggcgcagccccgtccgtgcagacccaccgccccttcctgggcgccttcgcc
cccgggccacagttcgcactgggccccatgtcgctacaggccaacctgggcccatctgtg
ctgcagtccctgttcagttccgtgcccgccgccggcctggttcacgtctcgaccgccgcc
accagattgaccaactcgcacgccatgggcagcttctcctctggggtggccggcggcgca
gttggaggtaggcagtgccctcctggccacttggtcccacaggacccgctgagggacgag
ctgggggccgcacgttgtctccgccgcccacccagactgttgggtttaaccaccgctgtt
tgcaggttcccttccagggccccctga
DBGET
integrated database retrieval system
