Bison bison bison (American bison): 104980280
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Entry
104980280 CDS
T08726
Symbol
ROCK1
Name
(RefSeq) rho-associated protein kinase 1 isoform X1
KO
K04514
Rho-associated protein kinase 1 [EC:
2.7.11.39
]
Organism
bbis
Bison bison bison (American bison)
Pathway
bbis04022
cGMP-PKG signaling pathway
bbis04024
cAMP signaling pathway
bbis04062
Chemokine signaling pathway
bbis04071
Sphingolipid signaling pathway
bbis04270
Vascular smooth muscle contraction
bbis04350
TGF-beta signaling pathway
bbis04360
Axon guidance
bbis04510
Focal adhesion
bbis04520
Adherens junction
bbis04530
Tight junction
bbis04611
Platelet activation
bbis04670
Leukocyte transendothelial migration
bbis04810
Regulation of actin cytoskeleton
bbis04921
Oxytocin signaling pathway
bbis05135
Yersinia infection
bbis05163
Human cytomegalovirus infection
bbis05200
Pathways in cancer
bbis05205
Proteoglycans in cancer
bbis05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
bbis00001
]
09130 Environmental Information Processing
09132 Signal transduction
04350 TGF-beta signaling pathway
104980280 (ROCK1)
04071 Sphingolipid signaling pathway
104980280 (ROCK1)
04024 cAMP signaling pathway
104980280 (ROCK1)
04022 cGMP-PKG signaling pathway
104980280 (ROCK1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
104980280 (ROCK1)
04520 Adherens junction
104980280 (ROCK1)
04530 Tight junction
104980280 (ROCK1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
104980280 (ROCK1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
104980280 (ROCK1)
04670 Leukocyte transendothelial migration
104980280 (ROCK1)
04062 Chemokine signaling pathway
104980280 (ROCK1)
09152 Endocrine system
04921 Oxytocin signaling pathway
104980280 (ROCK1)
09153 Circulatory system
04270 Vascular smooth muscle contraction
104980280 (ROCK1)
09158 Development and regeneration
04360 Axon guidance
104980280 (ROCK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
104980280 (ROCK1)
05206 MicroRNAs in cancer
104980280 (ROCK1)
05205 Proteoglycans in cancer
104980280 (ROCK1)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
104980280 (ROCK1)
09171 Infectious disease: bacterial
05135 Yersinia infection
104980280 (ROCK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
bbis01001
]
104980280 (ROCK1)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
bbis03036
]
104980280 (ROCK1)
Enzymes [BR:
bbis01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.39 ROCK-subfamily protein kinase
104980280 (ROCK1)
Protein kinases [BR:
bbis01001
]
Serine/threonine kinases: AGC group
DMPK family [OT]
104980280 (ROCK1)
Chromosome and associated proteins [BR:
bbis03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
104980280 (ROCK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Rho_Binding
PH
C1_1
Cortex-I_coil
Pkinase_C
APH
Motif
Other DBs
NCBI-GeneID:
104980280
NCBI-ProteinID:
XP_010827209
Ensembl:
ENSBBBG00000021280
UniProt:
A0A6P3GKA5
LinkDB
All DBs
Position
Unknown
AA seq
1354 aa
AA seq
DB search
MSTGDSFETRFEKIDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYK
DTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAF
FWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTA
EVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDY
ISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFP
DDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLS
SDIDTSNFDDLEEDKGDEETFPIPKAFVGNQLPFVGFTYYSNRRYLSSANPNDNRTSSNV
DKSLQENLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLEST
VSQIEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKL
AQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSITQLESLNRELQERNRILENSKSQMD
KDYYQLQAVLEAERRDRGHDSEKIGDLQARITSLQEEVKHLKHNLERVEGERKEAQDMLN
HSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKL
KEERDAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLIENKDRMEDEVKNLTLQLEQES
NKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMR
ELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQSEKETLATQLDLAETKAE
SEQLARGLLEEQYFELTQESKKAASRNRQEITDKDHTLSRLEETNSMLTKDIELLRKENE
ELTDKMRKAEEEYKLKKEEEINILKAAFEKNINTERTLKTQAVNKLAEIMNRKDFKIDRK
KANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNEMQAQLVEECTHKNELQMQL
ASKESDIEQLRAKLLDLSDSTSVASFPSADETDGNLPESRIEGWLSIPNRGNIKRYGWKK
QYVVVSSKKILFYNDEQDKEQSNPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQILY
ANEGECRKDLEVEPVQQAEKTNFQNHKGHEFIPTLYHFPANCEACAKPLWHVFKPPPALE
CRRCHVKCHRDHIDKKEDLISPCKVSYDVTSARDMLLLACSQDEQKKWVTHLVKKIPKNP
PSGFVRASPRTLSTRSTANQSFRKVVKNTSGKAS
NT seq
4065 nt
NT seq
+upstream
nt +downstream
nt
atgtcgactggcgacagttttgagactcggtttgaaaaaatcgacaacctgctgcgggat
cccaaatcggaagtgaattcagattgtctgctggatggattggatgctttggtatatgat
ttggattttcctgccttaagaaaaaacaaaaatattgacaactttttaagcagatataaa
gacacaataaataaaattagagatttacgaatgaaagctgaagattatgaagtagtgaag
gtgattggtagaggtgcatttggagaagttcaattggtaaggcataaatccaccaggaag
gtgtacgctatgaagctcctcagcaaatttgaaatgattaagagatctgattctgctttt
ttctgggaagaaagggacatcatggcttttgctaacagtccttgggttgttcagctgttt
tatgcattccaagatgatcgttatctctacatggtaatggaatacatgcctggtggagat
cttgtaaatttaatgagcaactatgacgtgcctgaaaaatgggcccgattctatactgca
gaagtagttcttgcattggatgcaatccattccatgggttttatccatagagatgtgaag
cctgataacatgctgctggataaatctggacatttgaagttagcagattttggtacttgt
atgaagatgaataaggaaggcatggtacgatgtgatacagcagttggaacacctgattat
atttctcctgaagtattaaaatctcaaggtggcgatggttattatggacgagaatgtgac
tggtggtcagttggggtatttttatatgaaatgcttgtaggtgatacaccattttatgca
gattctctggttggaacttacagtaagattatgaaccataaaaattctcttaccttccct
gatgataatgacatatcaaaagaagcaaaaaatcttatttgtgccttccttactgacaga
gaggtgagattagggcgaaatggtgtagaagaaatcaaacgacatctcttcttcaaaaat
gatcagtgggcttgggaaacacttcgagacactgtagcaccagttgtacctgatttaagt
agtgacatagacacaagtaactttgatgacttggaagaagataaaggagatgaagaaaca
ttccctatacctaaagcttttgttggcaatcaactaccttttgtaggatttacatattat
agcaatcgtagatacttatcttcagcaaatcctaacgataacagaactagctctaatgtg
gataaaagcttgcaggaaaatttgcagaaaacaatttataagctggaagaacagttacat
aatgaaatgcaattaaaagatgaaatggagcagaagtgcagaacgtcaaacataaaacta
gacaagataatgaaagaattggacgaagaggggaatcaaagaagaaatctagaatctaca
gtatctcagattgagaaggagaaaatgttgctacagcacagaattaatgaataccaaaga
aaagcagaacaggaaaatgagaagaggaggaatgtagaaaatgaagtttctacattaaag
gatcagttggaagacttaaagaaagtcagccagaattcacagcttgctaatgagaagctg
gcacaattacaaaagcagctagaagaagccaatgacttacttaggacagaatcagacaca
gcggttagattaaggaagagtcacacagagatgagcaaatccatcactcagctagagtcc
ctaaacagagaactgcaggagagaaatagaattttagagaattccaagtcacaaatggac
aaagattattaccaactacaggctgtattagaagctgaacgaagagacagaggtcatgat
tctgagaagattggagacctacaagctcgaattacatctttacaagaggaggtgaagcat
ctcaaacataatcttgaaagagtggaaggagaaagaaaagaggctcaagacatgcttaat
cattcagaaaaggaaaagaataacttagaaatagatttaaactacaagcttaaatcatta
cagcaacgattagaacaagaggtaaatgaacataaagtaaccaaagctcgtttaactgac
aaacatcaatctattgaagaggcaaagtctgttgcaatgtgtgagatggaaaaaaagctg
aaggaggagagagacgctcgagagaaggctgaaaatagggttgttcagattgagaagcag
tgctctatgctagatgttgatctgaagcaatctcagcagaagctggagcatttgattgaa
aataaagacaggatggaggatgaagttaagaatctaacgctacagctggagcaggaatca
aacaagcgacttttgttacaaaatgaattgaagactcaagcatttgaggcagacaattta
aaaggtttagaaaagcagatgaaacaggaaataaatactttattggaagcaaagagatta
ttggaatttgaattagctcagcttacaaaacagtacagagggaatgaagggcagatgcgg
gagctgcaggatcagctggaagcggagcagtatttctcgacactttataaaacccaggta
aaggaacttaaggaagaaattgaagaaaaaaacagagaaaacttaaagaaaatacaggaa
ctacaaagtgaaaaagaaactcttgctactcagttggatctagcggaaacaaaggctgaa
tctgagcagttggctcgagggcttctggaagaacagtattttgaactgacccaagaaagc
aagaaagctgcctcaagaaatagacaagagattacagataaagatcacactcttagtcgg
cttgaagaaacgaatagcatgctaaccaaagatattgaattattaagaaaagaaaacgaa
gagctaactgataaaatgaggaaggcagaggaagaatataaattgaagaaggaggaggag
atcaatatccttaaagctgcctttgaaaagaatatcaatacagaacgaacccttaaaaca
caggctgttaacaagttggcagaaataatgaatcgaaaggactttaaaatcgatagaaag
aaagcaaatacgcaggatttgagaaagaaagaaaaagaaaatcgaaagctccaacttgaa
ctcaaccaggaaagagagaaattcaaccaaatggtagtgaaacatcagaaggagctgaat
gaaatgcaagcgcaattggtagaagaatgtacacataagaatgagcttcagatgcagctg
gccagcaaagagagtgacattgagcagctgcgtgccaaactgttggacctttcagattct
acaagtgttgctagttttcccagtgctgatgaaactgatggaaaccttccagaatcaaga
attgaaggttggctttcaataccaaatagaggaaatatcaaaagatatggctggaagaaa
cagtatgttgtggtaagcagcaaaaaaattttgttctataatgatgaacaagataaggaa
caatccaatccgtctatggtattggacattgataaattgtttcatgttcgtcctgtaaca
caaggagatgtatacagagctgaaactgaagaaattcctaaaatattccagatactgtat
gcaaatgaaggtgaatgtagaaaagacttagaggtggaaccagtacaacaagctgaaaaa
acaaattttcaaaatcacaaaggccatgagttcattcctacactctaccactttcccgcc
aactgtgaggcctgtgccaaacctctctggcatgtttttaagccaccccctgccctggag
tgtcgaagatgccatgttaagtgccacagagaccacatagataagaaagaggacttgatt
tctccatgtaaagtaagttatgatgtaacatcagcaagagatatgctgctgctagcgtgt
tctcaggatgaacaaaaaaaatgggtaactcatttagtaaagaagatccctaagaatcca
ccatctggttttgtgcgtgcatcccctcgaacactttctacaaggtccactgcaaatcag
tctttccggaaagtggtcaaaaatacatctggaaaagctagttaa
DBGET
integrated database retrieval system