Bison bison bison (American bison): 104981243 Help Entry 104981243         CDS       T08726                                  Symbol EP300 Name (RefSeq) histone acetyltransferase p300   KO K04498   E1A/CREB-binding protein [EC:2.3.1.48] Organism bbis  Bison bison bison (American bison) Pathway bbis03083   Polycomb repressive complex bbis03250   Viral life cycle - HIV-1 bbis04024   cAMP signaling pathway bbis04066   HIF-1 signaling pathway bbis04068   FoxO signaling pathway bbis04110   Cell cycle bbis04310   Wnt signaling pathway bbis04330   Notch signaling pathway bbis04350   TGF-beta signaling pathway bbis04520   Adherens junction bbis04630   JAK-STAT signaling pathway bbis04720   Long-term potentiation bbis04916   Melanogenesis bbis04919   Thyroid hormone signaling pathway bbis04922   Glucagon signaling pathway bbis04935   Growth hormone synthesis, secretion and action bbis05016   Huntington disease bbis05152   Tuberculosis bbis05161   Hepatitis B bbis05164   Influenza A bbis05165   Human papillomavirus infection bbis05166   Human T-cell leukemia virus 1 infection bbis05167   Kaposi sarcoma-associated herpesvirus infection bbis05200   Pathways in cancer bbis05203   Viral carcinogenesis bbis05206   MicroRNAs in cancer bbis05211   Renal cell carcinoma bbis05215   Prostate cancer Brite KEGG Orthology (KO) [BR:bbis00001]  09120 Genetic Information Processing   09126 Chromosome    03083 Polycomb repressive complex     104981243 (EP300)   09125 Information processing in viruses    03250 Viral life cycle - HIV-1     104981243 (EP300)  09130 Environmental Information Processing   09132 Signal transduction    04310 Wnt signaling pathway     104981243 (EP300)    04330 Notch signaling pathway     104981243 (EP300)    04350 TGF-beta signaling pathway     104981243 (EP300)    04630 JAK-STAT signaling pathway     104981243 (EP300)    04066 HIF-1 signaling pathway     104981243 (EP300)    04068 FoxO signaling pathway     104981243 (EP300)    04024 cAMP signaling pathway     104981243 (EP300)  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     104981243 (EP300)   09144 Cellular community - eukaryotes    04520 Adherens junction     104981243 (EP300)  09150 Organismal Systems   09152 Endocrine system    04922 Glucagon signaling pathway     104981243 (EP300)    04935 Growth hormone synthesis, secretion and action     104981243 (EP300)    04919 Thyroid hormone signaling pathway     104981243 (EP300)    04916 Melanogenesis     104981243 (EP300)   09156 Nervous system    04720 Long-term potentiation     104981243 (EP300)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     104981243 (EP300)    05206 MicroRNAs in cancer     104981243 (EP300)    05203 Viral carcinogenesis     104981243 (EP300)   09162 Cancer: specific types    05211 Renal cell carcinoma     104981243 (EP300)    05215 Prostate cancer     104981243 (EP300)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     104981243 (EP300)    05161 Hepatitis B     104981243 (EP300)    05164 Influenza A     104981243 (EP300)    05167 Kaposi sarcoma-associated herpesvirus infection     104981243 (EP300)    05165 Human papillomavirus infection     104981243 (EP300)   09171 Infectious disease: bacterial    05152 Tuberculosis     104981243 (EP300)   09164 Neurodegenerative disease    05016 Huntington disease     104981243 (EP300)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03000 Transcription factors [BR:bbis03000]     104981243 (EP300)    03036 Chromosome and associated proteins [BR:bbis03036]     104981243 (EP300)    03029 Mitochondrial biogenesis [BR:bbis03029]     104981243 (EP300) Enzymes [BR:bbis01000]  2. Transferases   2.3  Acyltransferases    2.3.1  Transferring groups other than aminoacyl groups     2.3.1.48  histone acetyltransferase      104981243 (EP300) Transcription factors [BR:bbis03000]  Eukaryotic type   Other transcription factors    Pocket domain CBP     104981243 (EP300) Chromosome and associated proteins [BR:bbis03036]  Eukaryotic type   Histone modification proteins    HATs (histone acetyltransferases)     104981243 (EP300) Mitochondrial biogenesis [BR:bbis03029]  Mitochondrial quality control factors   Regulator of mitochondrial biogenesis    Coactivators     104981243 (EP300) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  HAT_KAT11 KIX zf-TAZ RING_CBP-p300 Creb_binding PHD_P300 Bromodomain ZZ KIX_2 Med15_N Motif Other DBs NCBI-GeneID:  104981243 NCBI-ProteinID:  XP_010828550 Ensembl:  ENSBBBG00000004102 UniProt:  A0A6P3GQ00 LinkDB All DBs Position Unknown AA seq 2399 aa AA seqDB search MAENVVEPGPPSAKRPKLSSPALSASASDGTDFGSLFDLEHDLPDELINSTELGLTNGGD ISQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQGMASQAQQNSPGLGLINS MVKSPMAQAGLTSPNMGMGTSGPNQGPTPSATGVMSSPVSQPAMGMNTGMNAGMSPGMLT AGNGQGMMPNQVMNGSIGAGRGRPNMQYPNPGMGSAGNLMTEPLQQGSPQMGGQTGLRGP QPLKMGMMNNPNPYGSPYTQNSGQQMGASGLGLQIPTKSVLPNSLSPFAMDKKAVPGGGM PNMGQQQAPQVQQPGLVAPVAQGMGSGAHTADPEKRKLIQQQLVLLLHAHKCQRREQANG EVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKN AGDKRNQQSILTGAPVGLGSTSSLGVGQQSTPSLSTVSQIDPSSIERAYAALGLPYQVNQ MPTQPQVQAKNQQNQQSGQSPQGMRPMSNMSASPMGVNGGVGVQPSNLLSDSMLHSAINS QNPLMSDNGSVASLGPMPTAAQPSSTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAA LKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLP SAASMVPVMNTGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRVTPQPGLNQFGQISM PQPPIGPRQNSPLQHHVQLAQTGTLNPPMGYGPRMQQPSSQSQFLPQTQFSTQGMNVTNM PLAPSGGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPPLPQPALHQNSPSPVPSRTP TPHHTPPSIGAQQPPATAIPAPVPTPPAMPPGPQSQVLHPPPRQTPTPPPTQLPPQVQPS LPAAPSVDQAQQQPLSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSST EVNSQTIPEKQPSQEVKMEPKMEVEAPEPADTQPEDIPETKAEDCKVEPTETEERGTELK TETKEEEDQPSTSATQSSPAPGQSKKKIFKPEELRQALMSTLEALYRQDPESLPFRQPVD PQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYK YCSKLSEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLCTIPRDATYYSYQNRYHF CEKCFNEIQGESVSLGDDPSQPQTTINKEQFSKRKNDTLDPELFVECTECGRKMHQICVL HHEIIWPSGFVCDGCLKKTARTRKENKFSAKRLPSTRLGTFLENRVNEFLRRQNHPESGE VTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTKALFAFEEIDGVDLCFFGMHVQE YGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEILIGYLEYVKKLGYTTGHIWACPP SEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHDYKDILKQATEDRLTSAKE LPYFEGDFWPNVLEESIKELEQEEEERKREENTSNESTDVTKGDSKNAKKKNNKKTSKNK SSLSRGNKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLIAGPAANSLPPIVDPDPLIP CDLMDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETR WHCTVCEDYDLCITCYNTKNHDHKMEKLGLGLDDESNNQQAAATQSPGDSRRLSIQRCIQ SLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENK CPVPFCLNIKQKLRQQQLQHRLQQAQMLRRRMASMQRTGVVGQQQGLPSPTPATPTTPTG QQPTTPQTPQPPPXSQPQPTPPNNMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQTAQPPL PGPPPAAVEVAMQIQRAAETQRQMAHVQIFQRPIQHQMPQMTPMAPMGMNPPPMARGPGG HLEPGMGPTGMQQQPPWAQGGLPQPQQLQSGMPRPAMMSVSQHGQPLNMPPQPGLGQVGV SPLKPGTVSQPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPLPGQPGLQPPA MPGQQGVHSSPAMQNLNPMQAGVPRAGLPQQPTQQQQLPPPMGGMSPQAQQMNMNHSTMP SQFRDILRRQQMMQQQQQGAGPGMGPGLANHNQFQPPQGVGYPAPQQQPPPRMQHHMQQI PQGSMGQMGQLPQALGAEAGASLQAYQQRLLQQQMGSPAQPNPMSPQQHMLPSQAQSPHL QGQQIPSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHVSPQTSSPHPGLVAAQ GNPMEQGHFASPDQNSMLSQLASNPGMANLHGASATDLGLGTDNSDLNSNLSQSTLDIH NT seq 7200 nt NT seq  +upstreamnt  +downstreamnt atggccgagaatgtcgtggaaccggggccgccttcagccaagcggcctaaactctcatct ccggccctctcggcgtccgccagcgatggcacagattttggctctctgtttgacttggag cacgacttaccagatgaattaatcaactctacagaattgggactaaccaatggtggtgat attagtcagcttcagacaagtcttggcatagtacaagatgcagcctctaaacataaacag ctgtcagaattgctacggtctggtagttcccctaacctcaatatgggggttggtggccca ggccaaggcatggccagccaagcccaacagaacagtcctggattaggtttgataaatagc atggtcaaaagcccaatggcccaggcaggcttgacttctcccaacatggggatgggcact agtgggccaaatcagggccccacgccgtctgcaacaggtgtgatgagcagtcccgtcagt cagcctgccatgggaatgaacacggggatgaacgctggcatgagtcccggcatgctgact gccggcaatggacaagggatgatgcctaatcaagtcatgaacggttcaattggagcaggc cgggggcgaccgaatatgcagtacccgaacccaggcatgggaagtgctggcaacttaatg actgagccgctgcagcaaggctctccccagatggggggacagacgggactgagaggcccc cagcctctcaagatgggaatgatgaacaaccctaatccttacggttcaccatacactcag aattctggacagcagatgggagccagtggccttggtctccagattccgacaaagtctgta ctaccaaatagcttatctccatttgcaatggacaaaaaggcagttcctggtggaggaatg cccaatatgggccagcagcaggccccacaggtccagcagccaggcctggtggctccggtg gcccaggggatgggttctggggcacatacggctgatccggagaagcgcaagctcatccag cagcagcttgtcctcctcctgcatgctcacaagtgccagcgccgggagcaggccaacggg gaggtgaggcagtgcaaccttccccactgtcgaaccatgaagaacgtcctaaaccacatg acacactgccagtcgggcaagtcctgccaagtggcacactgtgcatcttctcgacaaatc atttcccactggaagaattgtacaaggcatgattgtcctgtgtgtctccccctgaaaaac gctggagataagagaaatcaacagtcaattttgactggagcaccagttggacttggcagt actagctctctaggggtgggtcaacagtccactcccagcctaagcactgtcagtcagatt gatcccagctctatagaaagagcctatgcagcccttggactgccctatcaagtaaatcag atgccgacccagccccaggtgcaagcgaagaatcagcagaaccagcagtctgggcagtct ccccaagggatgcggcccatgagcaacatgagtgctagtcctatgggagtaaatggaggt gtaggggttcaaccgtcgaatcttctttctgactcgatgttgcattcagccataaattct caaaacccactgatgagtgacaatggcagtgtggcctctctgggtcctatgccaacagca gctcaaccatccagtactggaattcggaagcaatggcatgaagatattactcaggatctt cgaaatcatcttgtccacaaactcgttcaagccatatttcccactccggatcctgctgct ttaaaagacagacggatggaaaacctagttgcatatgcccggaaagtggaaggggacatg tatgaatcggcaaacaatcgagcggaatactaccacctgctagctgagaagatctataag attcagaaggaactagaagaaaagcgaaggactagactacagaaacagaacatgctacca agtgctgcaagcatggtgccagttatgaacacagggcctaacatggggcagccacaacca ggaatgacttctaatggccctctccctgatccatctatgatccgcggcagtgtgccaaac cagatgatgcctcgggtaactccacagcctggtttgaatcagtttggccagataagtatg cctcagccccctattggaccccggcaaaactctcctcttcagcaccatgtacagttagct caaactggaacacttaacccgcctatgggctacgggcctcgcatgcagcagccttccagc cagagccagtttcttcctcagactcaattctcaacacagggaatgaatgtaacaaatatg cctttggctccgtctggcggtcaagcaccagtgtctcaagcacagatgtccagttcttcc tgtcctgtgaactctcctataatgcctcctgggtctcaagggagccacattcactgtccc cctctccctcaaccagctctgcatcagaactcaccctcacccgtacctagtcgcaccccc acccctcaccacactccccctagcataggggctcagcagccaccagcaacagcaatccca gcccctgttcctacgcctccagccatgccacctggcccacagtcccaggttctccatccg cctccaagacagacgcctacgccgccaccaacacaacttcctccccaagtgcagccttcg cttcctgctgctccctcagtcgaccaggcgcagcagcagcctctgtcccagcaaagcaca gcagcctctgtgcccaccccgacggcacccctgctgcctccgcagccggcaactccactt tcccagccagctgtaagcatcgaagggcaggtatcaaaccctccatccactagtagcacg gaagtgaattctcagaccattcctgagaagcagccttcacaggaagtaaaaatggagcct aaaatggaagtggaggcaccagaaccagcagatactcagccggaggatattccagagact aaagcagaagactgtaaagtagaacctacagaaaccgaagagagaggcactgaattaaaa actgagacaaaagaggaagaagaccagccaagtacttcagcgacccagtcatctccagcc ccaggacagtcaaagaagaagattttcaaacctgaagagttacgacaggcactgatgtca acactggaggcactttaccgacaggatccggaatcccttcccttccgtcagcctgtggac cctcagcttctaggaatccctgattactttgatattgtgaagagccctatggatctttct accatcaagaggaagttagacactggacagtatcaggagccctggcagtatgtggatgac atttggctcatgttcaacaatgcttggttatataatcggaaaacatcacgggtgtacaaa tactgctccaagctgtctgaggtcttcgaacaagaaattgaccctgtcatgcaaagcctt ggatactgttgtggcagaaagttggagttctctccacagacactctgttgctatggcaaa cagttatgcacaatccctcgtgatgccacttactacagttatcagaacaggtatcatttc tgtgagaagtgtttcaatgaaatccaaggggagagcgtttctttgggggatgacccttcc caacctcaaactacaataaataaagaacaattttcaaagagaaaaaatgacactctggat cctgaactgtttgttgagtgtacagagtgtgggagaaagatgcatcagatctgtgtcctc catcacgagatcatctggccatcgggatttgtctgtgatggttgtttaaagaagactgca cgaactagaaaagaaaataagttttctgctaaaagactgccatctaccaggcttgggaca tttctggagaatcgtgtgaatgagtttctgaggcgacaaaatcaccctgagtcaggagag gtcactgttcgagtagttcatgcttctgacaaaactgtggaagtcaaaccaggcatgaaa gcaagatttgtagatagtggagagatggcagaatcctttccatatcgaaccaaagcgctc tttgccttcgaagagatcgatggtgttgacttgtgcttctttggtatgcacgttcaagag tatggctctgactgccctccgcccaaccagaggagagtatacatatcatacctcgatagt gttcacttcttccgtcctaaatgcttgaggactgcggtctatcatgaaatcctaattgga tatttggaatatgtcaagaaattaggatacacaacagggcatatttgggcgtgtccgcca agtgaaggagacgactacatcttccattgccacccccctgaccagaagatacccaagccc aagcgactgcaggagtggtacaaaaagatgctcgacaaagctgtgtccgagcgaatcgtc catgattataaggacattttaaaacaagctactgaagatcgattgacaagtgcgaaggaa ttgccttactttgagggtgatttctggcccaacgtcctggaagagagcattaaggaactg gaacaggaggaggaggagcggaagcgggaggagaacaccagcaacgagagcacagatgtg acaaagggagacagcaaaaatgctaaaaagaaaaacaacaagaaaactagcaaaaacaag agcagcctgagtcgtggcaataagaagaagccaggcatgcctaacgtatccaacgacctc tcacagaaattgtatgccaccatggagaagcacaaagaggtcttctttgtgatccgtctc atcgctggccctgccgccaactccctgcctcccattgttgaccccgaccccctcatcccc tgtgacctgatggatgggcgggatgcctttctcacccttgcaagggacaagcacctggag ttctcgtcgttgcgaagagcccagtggtccaccatgtgcatgctggtggagctgcacacc cagagccaggaccgctttgtctacacctgcaacgagtgcaagcaccacgtggagacacgc tggcactgcaccgtgtgtgaggattatgacttgtgtatcacctgctacaacactaaaaac cacgaccacaagatggagaagctcgggctggggcttgatgacgagagcaacaaccagcag gctgccgccacgcagagcccgggagactcccgccgcctgagcatccagcgctgcatccag tcgctggtgcacgcctgccagtgccgcaacgccaactgctcgctgccgtcctgccagaag atgaagcgggtggtgcagcacaccaagggctgcaagcgcaagaccaacggtggctgcccc atctgcaaacagctcatcgccctgtgctgctaccatgccaagcactgccaggagaacaag tgccccgtgcccttctgcctcaacatcaagcagaagctccggcagcagcagctgcagcac cggctccagcaggcccagatgctgcgcaggaggatggccagcatgcagcggactggtgtg gtggggcagcagcagggcctgccctcccctacccctgccacccctaccacgccgacgggc cagcagcccaccaccccgcagacaccccagcccccaccnnnntctcagccccagcccaca cctcccaacaacatgccgccctacttgcccaggactcaagctgctggcccagtgtcccag ggcaaggcagcaggccaggtgacccccccgacccctcctcagactgctcagcccccactt ccgggacccccacctgcagcagtggaggtggccatgcagattcagagggcagccgagacg caacgccagatggcccacgtgcaaatctttcagcggccgatccagcaccagatgccgcag atgactcccatggcccctatgggtatgaacccgccccccatggccagagggcctggtggg catttggagccagggatggggcccactggcatgcagcagcaacccccatgggcccaggga ggactgccccagccccagcagctgcagtccgggatgccccggccagccatgatgtcggtg tcacagcacgggcagcccctgaacatgcctccccagccgggcctgggccaggtaggtgtg agccctctcaagccaggcactgtgtctcaacccagctcccccctgcagcagcaacaggtg ctcagtatccttcatgccaacccccagctattggctgcgttcatcaaacagcgggctgcc aagtacgccaactccaacccgcagcccctccccgggcagccgggcctgcagccccccgct atgccaggtcagcagggggtccactccagccccgccatgcagaacttgaaccccatgcag gcaggtgtcccgagggctggcctgccccagcagcccacgcagcagcagcagctcccgcca cccatgggcgggatgagcccacaggctcagcagatgaacatgaatcacagcaccatgccc tcgcaattccgagacatcttgaggcgacagcagatgatgcagcagcagcagcagggagcg gggccagggatgggcccggggctggccaaccacaaccagttccagcctccccagggcgtg ggctaccctgccccgcagcagcagccgccaccgcgaatgcagcatcacatgcagcagata ccacaagggagcatgggacagatgggccagctcccgcaggccctgggagcagaggcggga gccagtctgcaggcctaccagcagcggctccttcagcaacagatgggctcaccggcccag cccaaccccatgagcccccagcagcacatgctcccgagtcaggctcagtccccgcacctc caaggccagcagatcccgtctctctccaatcaagtgcgatctccccagcctgtcccttct ccgcggcctcagtcccagcccccccactccagcccttccccacggatgcagcctcagcct tctccacaccacgtctccccacagaccagttctccacatcctggactggtcgctgcccag ggcaaccccatggaacaagggcattttgccagcccggaccagaattcgatgctctctcag ctcgctagcaatccaggcatggcaaacctccatggtgcgagcgccacggacctgggactc ggcaccgacaactcagacttgaattcaaacctctcacagagtacactagacatacactag

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