Bison bison bison (American bison): 104981877
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Entry
104981877 CDS
T08726
Symbol
CACNA1S
Name
(RefSeq) LOW QUALITY PROTEIN: voltage-dependent L-type calcium channel subunit alpha-1S
KO
K04857
voltage-dependent calcium channel L type alpha-1S
Organism
bbis
Bison bison bison (American bison)
Pathway
bbis04010
MAPK signaling pathway
bbis04020
Calcium signaling pathway
bbis04022
cGMP-PKG signaling pathway
bbis04024
cAMP signaling pathway
bbis04260
Cardiac muscle contraction
bbis04261
Adrenergic signaling in cardiomyocytes
bbis04270
Vascular smooth muscle contraction
bbis04723
Retrograde endocannabinoid signaling
bbis04725
Cholinergic synapse
bbis04726
Serotonergic synapse
bbis04727
GABAergic synapse
bbis04911
Insulin secretion
bbis04912
GnRH signaling pathway
bbis04921
Oxytocin signaling pathway
bbis04924
Renin secretion
bbis04925
Aldosterone synthesis and secretion
bbis04927
Cortisol synthesis and secretion
bbis04929
GnRH secretion
bbis04934
Cushing syndrome
bbis04935
Growth hormone synthesis, secretion and action
bbis05010
Alzheimer disease
bbis05020
Prion disease
bbis05022
Pathways of neurodegeneration - multiple diseases
bbis05207
Chemical carcinogenesis - receptor activation
bbis05410
Hypertrophic cardiomyopathy
bbis05412
Arrhythmogenic right ventricular cardiomyopathy
bbis05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
bbis00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
104981877 (CACNA1S)
04020 Calcium signaling pathway
104981877 (CACNA1S)
04024 cAMP signaling pathway
104981877 (CACNA1S)
04022 cGMP-PKG signaling pathway
104981877 (CACNA1S)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
104981877 (CACNA1S)
04929 GnRH secretion
104981877 (CACNA1S)
04912 GnRH signaling pathway
104981877 (CACNA1S)
04921 Oxytocin signaling pathway
104981877 (CACNA1S)
04935 Growth hormone synthesis, secretion and action
104981877 (CACNA1S)
04924 Renin secretion
104981877 (CACNA1S)
04925 Aldosterone synthesis and secretion
104981877 (CACNA1S)
04927 Cortisol synthesis and secretion
104981877 (CACNA1S)
09153 Circulatory system
04260 Cardiac muscle contraction
104981877 (CACNA1S)
04261 Adrenergic signaling in cardiomyocytes
104981877 (CACNA1S)
04270 Vascular smooth muscle contraction
104981877 (CACNA1S)
09156 Nervous system
04727 GABAergic synapse
104981877 (CACNA1S)
04725 Cholinergic synapse
104981877 (CACNA1S)
04726 Serotonergic synapse
104981877 (CACNA1S)
04723 Retrograde endocannabinoid signaling
104981877 (CACNA1S)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
104981877 (CACNA1S)
09164 Neurodegenerative disease
05010 Alzheimer disease
104981877 (CACNA1S)
05020 Prion disease
104981877 (CACNA1S)
05022 Pathways of neurodegeneration - multiple diseases
104981877 (CACNA1S)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
104981877 (CACNA1S)
05412 Arrhythmogenic right ventricular cardiomyopathy
104981877 (CACNA1S)
05414 Dilated cardiomyopathy
104981877 (CACNA1S)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
104981877 (CACNA1S)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
bbis04040
]
104981877 (CACNA1S)
Ion channels [BR:
bbis04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
104981877 (CACNA1S)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ion_trans
GPHH
Ca_chan_IQ
PKD_channel
CAC1F_C
Motif
Other DBs
NCBI-GeneID:
104981877
NCBI-ProteinID:
XP_010829431
Ensembl:
ENSBBBG00000009241
UniProt:
A0A6P3GIU9
LinkDB
All DBs
Position
Unknown
AA seq
1948 aa
AA seq
DB search
MEPAPAQDEGLRRKQAKKPVPEVLPRPPRALFCLTLQNPVRKACISIVEWKPFETIILLT
IFANCVALAVYLPMPEDDSNRLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRS
GWNVLDFIIVFLGVFTVILEQVNLIQSNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVP
SLQVVLNSIFKAMLPLFHIALLVLFMVVIYAIIGLELFKGKMHKTCYFIGTDIVATVENE
KPSPCARTGSGRPCTISGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYW
VNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLE
EDLRGYLSWITQGEVMDVDDLREGKLALDEGGSDTESLYEIAGLNKVIQFIRHWRQWNRV
FRWKCHDVVKSRVFYWLVILIVALNTLSIASEHHHQPLWLTHLQDVANRVLLALFTVEML
MKMYGLGLRQYFMSIFNRFDCFVVCSGLLEILLVESGAMSPLGISVLRCIRLLRIFKITK
YWTSLSNLVASLLNSIRSIASLLFLLFLFIVVFALLGMQLFGGRYDFEDTEVRRSNFDSF
PQALISVFQVLTGEDWNSVMYNGIMAYGGPSYPGVLVCIYFIILFVCGNYILLNVFLAIA
VDNLAEAESLTSAQKAKAEERRRRKMSKGLPDKSEEEKVTVAKKLEQKPKGEGIPTTAKL
KIDEFESNVNEVKDPYPSADFPGDDEEDEPEVPISPRPRPLAELQLKEKAVPIPEASAFF
IFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPLRAESVRNQVMAAKLWVLG
FSSDDACRLSPXMTTYGAFLHKGSFCRNYFNILDLXXXXXXXXQAGRELSLHSRPLGWAG
REKGQVPTRLPPLQHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFFSCNDLS
KMTEEECRGYYYVYKDGDPTQIEVRPRQWVHNAFHFDNVLSAMMSLFTVSTFEGWPELLY
KAIDSHEEDKGPVYNHRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCEL
DKNQRQCVQYALKARPLRCYIPKNPYQYRVWYIVTSSYFEYLMFALIMLNTICLGMQHYN
QSEQMNHISDILNVAFTIIFTLEMVLKLMAFKARGYFGDPWNVFDFLIVIGSIIDVILSE
IDTFLASSGGLYCLGGGCGNVVIPGCMSLPRSPTSSALQLACLGLAAGLHGADALRAPCP
EQAPEGPVGGGRRLCVTRVCMGVVGRGALADGIPVRPAHCLAPRPPRLRLSKPRALGPAR
EGPRTGRAVEPCTLSRHPRPQALPYVALLIVMLFFIYAVIGMQMFGKIALVDGTQINRNN
NFQTFPQAVLLLFRCATGEAWQEILLACSYGQLCDPESDYAPGEEYTCGTDFAYYYFLSF
YMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEATGRIKHLDVVT
LLRRIQPPLGFGKFCPHRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFE
QANEELRAIIKKVWKRTSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMRRQEEYY
GYRPKKDTVQIQAGLRTIEEEAAPEIRRTISGDLTAEEELERAMVEAAMEEGIFRRTGGL
FGQVDSFLERTNSLAPHMANQRPLQFTEIEMEEIESPVFLEDFPQSPSTHPLARANTNNA
NANVASGNGNHGNSPAFPSVHYEGELAGETETPATRGGLFGQPRGALGPHGKSRVEWPQG
QLPRRRTPRAQAPAASCQHAGAESQVPEEQSPTPGSLPGEAPPGSRTEDGTPGGPAPAMA
LLIREALVRGGLDSLAADANFIMATGQALAEACRMEPREVEVAAAELLQGRESLEGVPGA
RGCPGLGSSLGSLDLREGSQETLIPRRP
NT seq
5847 nt
NT seq
+upstream
nt +downstream
nt
atggagccggccccggcccaggacgagggcctgcggaggaagcaggccaagaagcccgtc
ccggaggtcctgcccaggccgccccgggccttgttctgcttgaccctccagaaccccgtg
cggaaagcctgcatcagcatcgtcgagtggaaacccttcgagaccatcatcttactcacc
atctttgccaactgcgtggccctggccgtgtacctgcccatgccggaggacgacagcaac
agactgaacctcggcctggagaagctggaatacttcttcctcatcgtcttctccatcgag
gccgccatgaagatcatcgcctacggcttcctgttccaccaggatgcctacctgcgcagc
ggctggaacgtgctggatttcatcatcgtcttcctgggggtcttcaccgtgatcctggag
caggtcaacctcatccagagcaacacggccccgatgagcagcaaaggcgcgggcctggac
gtcaaggcactgcgggccttccgcgtgctccgtccgctccggctggtgtccggggtgccc
agcctgcaggtggtcctcaactccatcttcaaggccatgctgccgctcttccacatcgcc
ctgctggtgctcttcatggtcgtcatctacgccatcatcggcctcgagctcttcaagggc
aagatgcacaagacctgctacttcattggcacggacatcgtggccacggtggagaacgag
aagccgtccccctgcgcccggacgggctccggccgcccctgcaccatcagcggcagcgag
tgccgtggcgggtggcccggccccaaccacggcatcacccacttcgacaacttcggcttc
tccatgctcaccgtgtaccagtgcatcaccatggagggctggaccgacgtcctctactgg
gtgaatgacgccatcgggaacgagtggccctggatctactttgtcaccctcatcctgctg
ggctccttcttcatcctcaacctggtgctgggcgtcctgagcggggaattcaccaaggag
cgggagaaggccaagtccagggggaccttccagaagctgcgggagaagcagcagctggag
gaggacctccggggctacctgagctggatcacgcagggcgaggtcatggacgtggatgac
ttgagagaagggaagctggctctggatgaaggcggctccgacacggagagcctgtacgaa
atcgcgggcttgaacaaagttatccagttcatccgacactggaggcagtggaaccgcgtc
ttccgctggaagtgccacgatgtggtgaagtccagggtcttctactggctggtcatcctg
atcgtcgctctcaacacactgtcgatcgcctcagagcaccaccaccagcctctctggttg
acccacctgcaagacgtggccaaccgggtgctgctggccctgttcaccgtggagatgctg
atgaagatgtacgggctgggcctgcgccagtacttcatgtccatcttcaaccgcttcgac
tgcttcgtggtgtgcagcggcctcctggagatcctgctggtggagtcgggtgccatgtcg
cccctgggcatctcggtgctgcgctgcatccgtctgctgcggatcttcaagatcaccaag
tactggacgtcgctgagcaacctggtggcgtcgctgctcaactccatccgctccatcgcc
tcgctgctcttcctgctcttcctcttcatcgtggtcttcgctctgctgggcatgcagctc
ttcgggggcaggtacgacttcgaggacaccgaggtgcggcgtagcaacttcgacagcttc
ccacaggcccttatcagcgtcttccaggtgctgacaggagaggactggaactccgtgatg
tacaacgggatcatggcctacggcggcccatcctaccccggggtgctcgtctgcatttac
ttcatcatcctgtttgtttgcggcaactacatcctgctcaacgtcttcctggccatcgct
gtggacaacctggcagaggccgagagcctgacttctgcccagaaggccaaggctgaagag
cggagacgcaggaagatgtccaagggtctcccggacaagtcagaggaggagaaggtgacg
gtggccaagaagctggagcagaaacccaagggggaaggtatccccaccaccgccaagctg
aagatcgacgagtttgaatccaacgtcaacgaggtgaaggacccctacccctcagctgac
ttcccaggggacgatgaggaagacgagccggaggtcccaataagcccccggccccgtccg
ctggctgagctgcagctgaaggagaaggcggtgcccattccagaagccagtgccttcttc
atcttcagccccaccaacaagatccgcgtcctgtgccaccgcattgtcaatgccacctgg
ttcactaacttcatcctgctcttcatcctgctcagcagtgccgccctggccgccgaggac
cccctccgggctgagtccgtgaggaaccaggtgatggcagccaagctctgggtgctgggt
tttagcagtgatgatgcatgccgcctctccccctagatgaccacctacggggccttcctg
cacaagggctccttctgccgcaactacttcaacatcctggacctgnnnnnnnnnnnnnnn
nnnnnnnaacaagctgggagggagctaagcttgcactcgaggcccctgggctgggctggg
cgtgagaaggggcaggtgccgaccaggctcccacccctgcagcacgtggtacagtgtgtg
ttcgtggccatccgcaccatcgggaacatcgtcctggtcaccaccctcctgcagttcatg
ttcgcctgcatcggcgtccagctcttcaaggggaagttcttcagctgcaatgacttgtcc
aagatgacggaggaggagtgcaggggctactactatgtgtacaaagatggagaccccaca
cagatagaggtgcgtccccgccagtgggtgcacaacgccttccacttcgacaacgtgctt
tcggccatgatgtccctcttcaccgtgtccaccttcgagggatggcctgagctgctgtac
aaggccattgactctcatgaggaggacaagggccccgtgtacaaccaccgcgtggagatg
gccattttcttcatcatctacatcatccttatcgccttcttcatgatgaacatcttcgtg
ggctttgtcatcgtcaccttccaggagcagggggagactgagtacaagaactgtgagctg
gacaagaaccagcgccagtgcgtgcagtacgccctgaaggcccggcccctgaggtgctac
atccccaagaacccctaccagtaccgggtgtggtacatcgtcacctcctcctacttcgag
tacctgatgttcgccctcatcatgctcaacaccatctgcctgggcatgcagcactacaac
cagtcggagcaaatgaaccacatctctgacatcctcaacgtagccttcaccatcatcttc
acactggagatggtcctcaagctcatggcgttcaaggccaggggctattttggggacccc
tggaacgtgtttgactttctgattgtcatcggcagcatcattgacgtcatcctcagtgag
atcgacactttcctggcctccagcgggggactgtattgcctgggtggcggctgcgggaac
gttgtaattccaggctgcatgagcctgccccgctcgcccaccagctctgccctgcagctt
gcatgcctgggcctggccgctggactgcatggggcagacgcgctcagggccccctgcccc
gagcaggcccccgagggtccggttgggggcgggcggagactctgtgtcaccagagtgtgc
atgggtgtggtgggacgtggggctctggcggacggaatccctgtccgcccagcgcactgc
ttggcgccccgcccaccccgcctccggctgagcaagcccagggccctgggccccgcgagg
gaagggccccgtaccgggcgcgcggtggagccctgcaccctgagccgccatcctcgcccg
caggccctgccctacgtggctctgctcatcgtcatgctcttcttcatctacgcggtcatc
ggcatgcagatgttcgggaagatcgccttggtggacgggacccagatcaaccggaacaac
aacttccagaccttcccccaggcggtgctgctgctcttcaggtgcgccacgggggaggcg
tggcaggagatcctgctggcctgcagctacggccagctgtgtgaccccgagtcggactat
gcccccggggaggagtacacctgtggcacggacttcgcctactactacttcctcagcttc
tacatgctgtgcgccttcctgatcatcaacctctttgtggccgtcatcatggacaacttt
gactacctgacacgggactggtccatcctgggccctcatcacctggatgagttcaaggcc
atctgggcggagtacgacccggaggctacgggcaggatcaagcacctggacgtggtgacc
cttctgaggaggatccagcccccgctgggcttcgggaagttctgcccccaccgggtagcg
tgtaagcggctggtgggcatgaacatgcccctcaacagcgacggcacggtcaccttcaac
gccacgctcttcgccctggtgcgcacagctctgaagatcaagacggaaggtaacttcgag
caggccaacgaggagctgcgagccatcatcaagaaggtctggaagaggaccagcatgaag
ctcctggaccaggtcatccctcccataggagatgacgaggtgacggtggggaagttctac
gccacgttcctcatccaggagcacttccggaagttcatgaggcgccaggaggagtattat
gggtaccggcccaagaaggacaccgtgcagatccaggctggactgaggaccatcgaggaa
gaggcagcccctgagatccgccgcaccatctcgggagacctgacggccgaagaggagctg
gagagagccatggtggaggccgcgatggaggaagggatcttccggaggaccggcggcctg
tttggccaggtggacagcttcctggaaaggaccaactcgttggccccgcacatggccaac
cagagacccctccagtttactgaaattgagatggaggagatagaatcgcccgtcttcctg
gaggacttccctcaaagtccgagtacccacccccttgctcgtgccaacaccaacaatgcc
aacgccaacgttgccagtggcaacggcaaccatggcaacagcccagcatttcccagtgtc
cactacgaaggggagctcgcaggggagacagagacgcctgccaccagaggaggactcttc
ggccagccccggggggccctggggccccacggcaagtcccgagtggagtggccgcaggga
cagcttccccggagaaggacgcccagggcccaggcccccgctgcctcctgccagcacgcg
ggagcagagtcccaggtgcccgaggagcagagccccaccccagggtccctgcccggggag
gcgccgcccggcagtaggacagaggacggaacccctgggggtccagctccagccatggcc
ctgctgatccgcgaggctctggttcgagggggcctggacagcttggcggcggatgctaac
ttcatcatggccacgggccaggcgctggcggaggcctgccggatggaaccgcgggaagtg
gaggtggcagccgcagagcttctgcagggacgcgagtccctggagggcgtgcctggtgcc
cgagggtgcccaggcctcgggtcctccctgggcagcctcgacctgcgtgagggctcccag
gagaccctgattccccgcaggccatga
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integrated database retrieval system