Bison bison bison (American bison): 104983369
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Entry
104983369 CDS
T08726
Symbol
NOTCH2
Name
(RefSeq) neurogenic locus notch homolog protein 2
KO
K20994
Notch 2
Organism
bbis
Bison bison bison (American bison)
Pathway
bbis01522
Endocrine resistance
bbis04330
Notch signaling pathway
bbis04658
Th1 and Th2 cell differentiation
bbis04919
Thyroid hormone signaling pathway
bbis05165
Human papillomavirus infection
bbis05200
Pathways in cancer
bbis05206
MicroRNAs in cancer
bbis05207
Chemical carcinogenesis - receptor activation
bbis05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
bbis00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
104983369 (NOTCH2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
104983369 (NOTCH2)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
104983369 (NOTCH2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
104983369 (NOTCH2)
05206 MicroRNAs in cancer
104983369 (NOTCH2)
05207 Chemical carcinogenesis - receptor activation
104983369 (NOTCH2)
09162 Cancer: specific types
05224 Breast cancer
104983369 (NOTCH2)
09172 Infectious disease: viral
05165 Human papillomavirus infection
104983369 (NOTCH2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
104983369 (NOTCH2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
EGF
hEGF
EGF_TEN
EGF_CA
EGF_2
Ank_2
Ank
NOD
Notch
NODP
Ank_5
Ank_3
Ank_4
EGF_Teneurin
EGF_3
Motif
Other DBs
NCBI-GeneID:
104983369
NCBI-ProteinID:
XP_010831129
Ensembl:
ENSBBBG00000007547
UniProt:
A0A6P3GW54
LinkDB
All DBs
Position
Unknown
AA seq
2449 aa
AA seq
DB search
MPALRPAPLWALLALWLCRAAPARALQCRDGYEPCVNEGICVTYHNGTGYCKCPEGFLGE
YCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCAPGFTGEDCQHSTTHPCFVSHPCLNGGT
CHVLSRDTYECTCQVGFTGKLCQWTDACLSHPCANGSTCTTMANQFSCTCLAGFTGQKCE
TDVNECDIPGQCQHGGTCLNLPGSYQCQCPQGFTGQHCDSPYVPCAPSPCVNGGTCRQTG
DFTFECSCLPGFEGVTCERNIDDCPNHKCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVD
ECLLQPNACQNGGTCTNRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASF
SCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGSDCTEDVDECA
MANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCKNDATCLDKIGGFTC
LCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTP
CLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYM
GAICSDQIDECYSSPCLNEGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCVHGVCM
DGVNRYNCVCSPGFTGQRCNIDIDECASNPCRKGATCINDVNGFRCICPEGPHHPSCYSQ
VNECLSNPCVHGNCTGGLTGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYR
CTCKKGFKGYNCQVNIDECASNPCLNQGTCLDDVSGYTCHCVLPYTGKNCQTVLAPCSPN
PCENAGVCKEAPNFESYSCLCAPGWQGQRCTIDIDECVSKPCMNHGLCHNTQGSYMCECP
PGFSGMDCEEDIDDCLANPCQNGGSCVDGVNTFSCLCLPGFTGDKCQTDMNECLSEARKV
HCENNIDECTESSCFNGGTCIDGINSFSCLCPVGFTGSFCLHEINECNSHPCLNEGVCVD
GLGTYRCICPLGYTGKNCQTLVNLCSRSPCKNKGTCIQDKAESRCLCPSGWAGAYCDVPS
VSCEVAASHRGVPVDRLCQHSGVCISAGNSHHCQCPLGYTGSYCEDQLDECSSNPCQHGA
TCRDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLC
EENVDDCARGPHCLNGGQCVDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCI
QLTNDYLCVCRSTFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARC
QSSCGQVKCRRGEQCVHTASGPRCFCPNPQDCDSGCASSPCQHGGSCYPQRQPPYYSCQC
APPFQGSHCELYTAPTSTPPATCLSQYCADKARDGICDDVCNSHACQWDGGDCSLTMEDP
WANCSSPLPCWEYINNQCDELCNTAECLFDNFECQKSSKTCKYDKYCADHYEDNHCDQGC
NSEECGWDGLDCAADRPENLAEGTLVIVVLMPPEQLLQDARRFLRALGTLLHTNLRIKRD
AQGELMVYPYYGGKSAAMKKQRLTRRSLPGDEEQEVAGSQVFLEIDNRQCVQDSDQCFKN
TDAAAALLASHAIQGTLSYPLVSVVSESLTPKRTQLLYLLAVAVVIILFIILLGVIMAKR
KRKHGSLWLPEGFTLRRDSSNHKRREPVGQDAVGLKNLSVQVSEANLIGSGTSEHWVDDE
GPQPKKAKAEDEALLSEEDDPIDRRPWTQQHLEAADIRRTPSLALTPPQAEQEVDVLDVN
VRGPDGCTPLMLASLRGGSSDMSDEDEDAEDSSANIITDLVYQGASLQAQTDRTGEMALH
LAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVAADAQGVFQILIRNRVTDLDARMN
DGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKSALHWAAAVNNVEATLLLLKNGAN
RDMQDNKEETPLFLAAREGSYEAAKILLDHFANRDITDHMDRLPRDVARDRMHHDIVRLL
DEYNVTPSPPGTVLTSALSPVICGPNRPFLSLKHTPMGKKSRRPNTKSTVPTSLPNLAKE
AKDAKGNRRKKSLSDKGQLSESSVTLSPVDSLESPHTYVSDTTSSPMITSPGILQASPNP
MLATAAPTAPVHAQHALSFSNLHEMQPLAHGANTVLPSVSQLLSHRHIVPPGSSTAGSLG
RLHSVTVPADWMNRVEMNESQYNEMFGMVLAPAEGTHPGIAPQSRPPEGKHLTTPREPLP
PIVTFQLIPKGSIAQPTGAAQPPSNCPPAVAGTLPTMYQIPEMARLPSMAFPTAMMPQQD
GQVAQTILPAYHAFPASVGKYPTPPSQHSYASSNAAERTPSHSGHLQGEHPYLTPSPESP
DQWSSSSPHSASDWSDVTTSPTPGGAGGGQRGPGTHMSEPPRSNMQVYA
NT seq
7350 nt
NT seq
+upstream
nt +downstream
nt
atgcccgccctgcgccccgctccgctgtgggcgctgctggcactgtggctgtgccgcgcg
gccccggcgcgtgcattgcaatgtcgggatggctatgagccttgtgtaaatgaaggaata
tgtgttacctaccacaacggtacaggatactgcaagtgtccagagggcttcttgggagaa
tattgtcagcatcgagacccctgtgagaagaaccgttgccagaatggtgggacgtgtgtg
gcccaggctatgttggggaaagccacgtgccgctgtgccccgggcttcacgggcgaggac
tgccagcactcgactactcacccctgctttgtgtctcacccctgcctgaatgggggcacc
tgccacgtgcttagccgggacacctacgagtgtacctgccaagtcggttttacaggtaaa
ctgtgccagtggactgatgcctgcctgtcccacccctgtgcaaacggaagtacctgtacc
actatggccaaccagttctcctgcacatgccttgcaggcttcacagggcagaaatgtgag
actgatgtcaatgagtgtgacattccaggacagtgccagcacggtggcacctgcctcaac
ctcccgggctcctatcagtgccagtgcccccagggcttcacaggccagcactgcgacagt
ccctatgtgccctgcgcaccctccccctgtgtcaacggaggtacctgccggcagaccggt
gactttacctttgagtgcagttgccttccaggttttgaaggagtcacctgtgagcggaat
atagatgactgtcctaaccacaagtgtcagaatggaggggtttgtgtggatggggtcaat
acctacaactgccgctgtccccctcagtggacaggacagttctgcacagaggatgtggat
gagtgcctgctgcaacccaatgcctgtcagaacgggggcacctgtaccaaccgcaacggg
ggctatggctgtgtatgtgtgaatggctggagtggggacgactgcagtgagaatatcgat
gactgtgccttcgcctcctgcaccccgggctctacctgcatcgatcgtgtggcctccttc
tcttgtatgtgcccagaaggaaaggcaggtctcttatgtcatctggatgacgcgtgcatc
agcaacccctgccacaagggggcgctgtgtgataccaaccctctgaatggacagtatatt
tgcacctgcccacaaggctacaaagggagtgactgtacagaagatgtggatgagtgtgcc
atggccaacagcaatccttgtgagcatgcaggaaaatgtgtgaacacagatggtgccttc
cactgtgagtgtctgaagggctatgcaggacctcgttgtgagatggacatcaatgagtgc
cactcagacccctgcaagaatgatgccacctgtttggataagattggaggcttcacgtgt
ctgtgcatgccaggtttcaaaggtgtgcattgtgagttggagataaatgaatgtcagagc
aacccttgtgtgaacaatggacagtgtgtggataaagtcaatcgcttccagtgtctgtgt
ccgcctggattcacgggaccagtttgccagatcgatattgacgactgttctagtactccg
tgtctgaatggggcaaagtgtatagatcacccgaatggctatgagtgccagtgtgccaca
ggattcactggtgtgttgtgtgaggagaacattgacaactgtgaccctgatccttgccac
cacggccagtgtcaggatggcattgattcctacacctgcatttgcaatccgggctacatg
ggcgccatctgcagtgaccagatagacgaatgctacagcagcccttgcctgaatgagggt
cgctgcatcgacctggtgaatggttaccagtgcaactgccagccaggcacgtcaggtgtt
aattgtgaaatcaattttgatgactgtgcaagtaacccgtgtgtccatggagtctgtatg
gatggcgttaatcgttacaactgtgtctgctcaccaggattcacagggcagagatgtaac
attgacattgatgagtgtgcctccaatccctgtcgcaagggtgcaacgtgcatcaatgat
gtgaacggtttccgctgtatctgccctgagggcccccaccatcccagctgctactcacag
gtgaacgagtgcctgagcaatccctgtgtccatggaaactgtactgggggcctcactgga
tacaagtgcctctgtgatgcaggctgggttggcatcaactgtgaagtggacaaaaatgaa
tgtctttctaatccatgccagaacgggggaacttgtgacaatctggtgaatggatacagg
tgcacttgcaagaagggctttaaaggctataactgccaggtgaatattgatgaatgtgcg
tcaaatccatgtctgaaccaaggaacctgccttgatgacgtaagcggttatacttgccac
tgtgtgctgccatacacaggcaagaactgtcagaccgtattggctccctgttccccaaac
ccttgtgagaatgctggtgtttgcaaagaggcaccaaattttgagagttactcctgcctg
tgtgctcctggctggcaaggtcagcggtgtaccatcgacattgatgagtgtgtctccaag
ccctgcatgaaccacggtctctgccataacacccagggcagctacatgtgtgaatgtcct
ccaggcttcagtggcatggactgtgaggaggacattgatgactgccttgccaatccttgc
cagaatggaggttcctgtgtagatggagtgaatactttctcctgcctgtgccttccgggc
ttcactggggataaatgtcagacagacatgaatgagtgtctgagtgaagcccggaaggtc
cactgtgagaacaacattgacgagtgcactgagagctcctgtttcaatggtggcacgtgt
atcgatgggattaactccttctcttgcttgtgccctgtgggcttcactggttccttctgc
ctccatgagatcaatgaatgcaactctcatccatgcctgaatgaaggagtatgtgttgat
ggcctgggtacctaccgctgtatctgcccattgggctacactggaaaaaactgtcagacc
ctggtgaacctctgtagtcggtctccatgtaaaaacaaaggtacttgcattcaggataaa
gcagagtcgcggtgcctgtgtccgtctggatgggctggtgcttactgcgatgttcccagt
gtctcctgtgaggtggcggcctcccacagaggggtgcccgttgaccgcttgtgccagcac
tcaggcgtctgtatcagtgcgggcaactcgcatcactgccagtgccccctgggctacacc
gggagctactgtgaggaccagcttgatgagtgctcgtccaatccctgccagcacggcgcc
acctgccgggacttcattggtggatacagatgtgagtgtgtccctggatatcagggtgtc
aactgcgagtatgaagtggatgagtgccagaaccagccatgccagaatgggggcacctgt
atcgaccttgtgaaccacttcaagtgctcctgcccaccaggcactcggggcctgctttgt
gaagagaacgttgacgactgtgccaggggtccccactgccttaatggtggccagtgtgta
gacaggattgggggctacagttgtcgctgcttgccaggctttgctggagaacgctgtgag
ggggacatcaacgagtgcctgtccaacccctgcagctctgagggcagcctggactgcata
cagctcaccaacgactacctgtgcgtctgccgcagcaccttcactggtcgtcactgtgaa
acgttcgtcgacgtgtgtccccagatgccttgcctgaacggaggcacttgtgctgtggcc
agcaacatgcccgatggtttcatctgtcgttgtcccccgggcttctctggggcgcggtgc
cagagcagctgcggacaggtgaagtgcaggagaggggagcagtgtgtgcacacggcctcg
ggcccccgctgcttctgccccaacccccaggactgcgactcgggctgcgccagtagcccc
tgccagcacggggggagctgctaccctcagcgccagcctccttactactcgtgccagtgt
gccccgccgttccagggcagccactgtgaactctacaccgcccccaccagcacccctcct
gccacctgcctgagccagtattgtgccgacaaagctcgggacggcatctgtgatgacgtg
tgcaacagccatgcctgccagtgggatgggggggactgttccctcaccatggaggacccc
tgggccaattgctcctccccgctgccctgctgggagtacatcaacaaccagtgcgacgag
ctgtgcaacacggccgagtgcctgtttgacaactttgaatgccagaagagtagcaagaca
tgcaaatatgacaaatactgtgcagaccactacgaagacaaccattgtgaccagggttgc
aacagtgaggagtgtggctgggatgggctggactgtgctgctgaccggccagaaaacctg
gcagagggcaccctggtcatcgtggtgctgatgccacctgaacagctgctccaggatgcc
cgcagattcttgcgggcactgggcaccctgctccacaccaacctccgcatcaaacgggat
gcccagggggaactcatggtctacccctattatggtgggaagtcagctgccatgaagaag
cagagactgacacgcaggtcccttcctggagatgaagaacaggaagtggctggctctcag
gtatttctggagattgacaaccgccagtgtgttcaagactcagaccagtgctttaagaac
acagacgcagccgcagctcttctggcttctcacgccatccaggggaccctgtcgtaccca
cttgtgtctgtcgtcagtgaatctctgaccccaaaacgcactcagcttctctatctgctt
gctgttgccgttgtcattatcttgtttattatcctgctgggggttatcatggcaaaacga
aagcgcaagcatggctccctctggctgcctgaaggtttcacccttcgccgtgactccagc
aaccacaaacgtcgtgagccagtgggccaggatgctgtgggactcaaaaatctttcagtg
caagtctcagaggcgaacctaattggttctggaacaagtgaacactgggtcgatgatgaa
gggccgcagcctaagaaagccaaggctgaagatgaggctttgctctcagaagaagatgac
cccatcgatcggcgtccatggacacagcagcacctggaagctgcagacatccgtaggaca
ccatcgctggctctcacccctccacaggcagagcaggaggtggacgtgctggatgtgaac
gtccgcggtccagatgggtgcaccccactgatgctggcttctctccgaggaggcagctca
gacatgagtgatgaagatgaagatgcagaggactcttccgccaacatcatcacggaccta
gtctaccagggtgccagcctccaagcacagacagacaggacgggtgagatggccctgcat
cttgcagcccggtactcaagggcagatgctgccaagcgtctcctggatgcaggtgcagat
gccaatgcccaggacaacatgggccgctgccctctccatgctgcagtggctgctgatgcc
caaggtgtcttccagatactgatccgcaaccgagtaactgatctagacgcaaggatgaat
gatggcactacacccctgatcctggctgcccgcctggcagtggagggaatggtggcagaa
ctgatcaactgccaagcagatgtgaatgcagtggatgaccatggaaaatctgcccttcac
tgggcagctgctgtgaataatgtggaggcaacccttttgctattgaaaaatggggccaac
cgagacatgcaggacaacaaggaggagacacccctgtttcttgctgcccgggaggggagc
tatgaagcagccaagatcctgttagaccattttgccaatcgggacatcacagaccacatg
gatcgccttccccgggacgtggcccgggaccgcatgcaccatgacatcgtgcgcctgctg
gacgagtacaacgtgacccccagccctcccggcacagtgctgacttctgcgctctcaccc
gtcatctgtgggcccaacaggccttttctcagtttgaagcataccccaatgggcaagaag
tctagacggcctaacaccaagagtaccgtgcccactagcctccctaaccttgccaaggag
gccaaggatgccaaggggaacaggaggaagaagtctctgagtgacaagggccagctgtcc
gagagctcagtgactctgtcccccgtcgattccctagaatctccgcacacatatgtttct
gacaccacctcctctccaatgatcacatcccccggaatcttacaggcctcccccaacccc
atgctggccactgccgcccccactgccccagtccatgcacagcatgcactgtctttctct
aaccttcatgagatgcagcccttggctcatggggccaacactgtgcttccctccgtgagc
cagctgctgtctcaccgccacattgtgcccccgggcagcagcaccgcagggagcttgggt
aggctgcattcagtcactgtcccggccgactggatgaaccgcgtggagatgaatgagagc
cagtacaacgagatgttcggtatggtcctggctccagctgagggcacccaccctggcata
gctccccagagcaggccgcctgaagggaagcatttaaccaccccacgagagcccttgccc
cccattgtgactttccagctaatccccaaaggcagcattgcccaaccaactggggctgcc
cagcctccgtccaactgccctccagctgttgcaggcaccctgcccaccatgtatcagatt
ccagaaatggctcgcttgcccagtatggcttttcccactgccatgatgccccagcaggat
gggcaggttgctcagaccattctcccagcctatcacgccttcccagcctccgtgggcaag
tatcccacacccccatcacagcatagctatgcttcctccaacgctgctgagagaacgccc
agtcacagtggtcacctccagggtgagcatccctacctgacaccgtccccagagtctcct
gaccagtggtcaagttcatcaccccactctgcttctgactggtcagatgtgaccaccagc
cccactcctgggggtgctggaggaggtcagcggggacctgggacacacatgtctgagcca
ccacgcagcaacatgcaggtctatgcatga
DBGET
integrated database retrieval system
