KEGG   Bison bison bison (American bison): 104986245
Entry
104986245         CDS       T08726                                 
Name
(RefSeq) RAC-gamma serine/threonine-protein kinase-like
  KO
K04456  RAC serine/threonine-protein kinase [EC:2.7.11.1]
Organism
bbis  Bison bison bison (American bison)
Pathway
bbis01521  EGFR tyrosine kinase inhibitor resistance
bbis01522  Endocrine resistance
bbis01524  Platinum drug resistance
bbis04010  MAPK signaling pathway
bbis04012  ErbB signaling pathway
bbis04014  Ras signaling pathway
bbis04015  Rap1 signaling pathway
bbis04022  cGMP-PKG signaling pathway
bbis04024  cAMP signaling pathway
bbis04062  Chemokine signaling pathway
bbis04066  HIF-1 signaling pathway
bbis04068  FoxO signaling pathway
bbis04071  Sphingolipid signaling pathway
bbis04072  Phospholipase D signaling pathway
bbis04140  Autophagy - animal
bbis04150  mTOR signaling pathway
bbis04151  PI3K-Akt signaling pathway
bbis04152  AMPK signaling pathway
bbis04210  Apoptosis
bbis04211  Longevity regulating pathway
bbis04213  Longevity regulating pathway - multiple species
bbis04218  Cellular senescence
bbis04261  Adrenergic signaling in cardiomyocytes
bbis04370  VEGF signaling pathway
bbis04371  Apelin signaling pathway
bbis04380  Osteoclast differentiation
bbis04510  Focal adhesion
bbis04517  IgSF CAM signaling
bbis04518  Integrin signaling
bbis04550  Signaling pathways regulating pluripotency of stem cells
bbis04611  Platelet activation
bbis04613  Neutrophil extracellular trap formation
bbis04620  Toll-like receptor signaling pathway
bbis04625  C-type lectin receptor signaling pathway
bbis04630  JAK-STAT signaling pathway
bbis04660  T cell receptor signaling pathway
bbis04662  B cell receptor signaling pathway
bbis04664  Fc epsilon RI signaling pathway
bbis04666  Fc gamma R-mediated phagosome formation
bbis04668  TNF signaling pathway
bbis04722  Neurotrophin signaling pathway
bbis04725  Cholinergic synapse
bbis04728  Dopaminergic synapse
bbis04810  Regulation of actin cytoskeleton
bbis04910  Insulin signaling pathway
bbis04914  Progesterone-mediated oocyte maturation
bbis04915  Estrogen signaling pathway
bbis04917  Prolactin signaling pathway
bbis04919  Thyroid hormone signaling pathway
bbis04920  Adipocytokine signaling pathway
bbis04922  Glucagon signaling pathway
bbis04923  Regulation of lipolysis in adipocytes
bbis04926  Relaxin signaling pathway
bbis04929  GnRH secretion
bbis04931  Insulin resistance
bbis04932  Non-alcoholic fatty liver disease
bbis04933  AGE-RAGE signaling pathway in diabetic complications
bbis04935  Growth hormone synthesis, secretion and action
bbis04936  Alcoholic liver disease
bbis04973  Carbohydrate digestion and absorption
bbis05010  Alzheimer disease
bbis05017  Spinocerebellar ataxia
bbis05132  Salmonella infection
bbis05135  Yersinia infection
bbis05142  Chagas disease
bbis05145  Toxoplasmosis
bbis05152  Tuberculosis
bbis05160  Hepatitis C
bbis05161  Hepatitis B
bbis05162  Measles
bbis05163  Human cytomegalovirus infection
bbis05164  Influenza A
bbis05165  Human papillomavirus infection
bbis05166  Human T-cell leukemia virus 1 infection
bbis05167  Kaposi sarcoma-associated herpesvirus infection
bbis05168  Herpes simplex virus 1 infection
bbis05169  Epstein-Barr virus infection
bbis05170  Human immunodeficiency virus 1 infection
bbis05200  Pathways in cancer
bbis05205  Proteoglycans in cancer
bbis05207  Chemical carcinogenesis - receptor activation
bbis05208  Chemical carcinogenesis - reactive oxygen species
bbis05210  Colorectal cancer
bbis05211  Renal cell carcinoma
bbis05212  Pancreatic cancer
bbis05213  Endometrial cancer
bbis05214  Glioma
bbis05215  Prostate cancer
bbis05218  Melanoma
bbis05220  Chronic myeloid leukemia
bbis05221  Acute myeloid leukemia
bbis05222  Small cell lung cancer
bbis05223  Non-small cell lung cancer
bbis05224  Breast cancer
bbis05225  Hepatocellular carcinoma
bbis05226  Gastric cancer
bbis05230  Central carbon metabolism in cancer
bbis05231  Choline metabolism in cancer
bbis05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
bbis05415  Diabetic cardiomyopathy
bbis05417  Lipid and atherosclerosis
bbis05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:bbis00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    104986245
   04012 ErbB signaling pathway
    104986245
   04014 Ras signaling pathway
    104986245
   04015 Rap1 signaling pathway
    104986245
   04370 VEGF signaling pathway
    104986245
   04371 Apelin signaling pathway
    104986245
   04630 JAK-STAT signaling pathway
    104986245
   04668 TNF signaling pathway
    104986245
   04066 HIF-1 signaling pathway
    104986245
   04068 FoxO signaling pathway
    104986245
   04072 Phospholipase D signaling pathway
    104986245
   04071 Sphingolipid signaling pathway
    104986245
   04024 cAMP signaling pathway
    104986245
   04022 cGMP-PKG signaling pathway
    104986245
   04151 PI3K-Akt signaling pathway
    104986245
   04152 AMPK signaling pathway
    104986245
   04150 mTOR signaling pathway
    104986245
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    104986245
   04518 Integrin signaling
    104986245
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    104986245
  09143 Cell growth and death
   04210 Apoptosis
    104986245
   04218 Cellular senescence
    104986245
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    104986245
   04550 Signaling pathways regulating pluripotency of stem cells
    104986245
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    104986245
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    104986245
   04613 Neutrophil extracellular trap formation
    104986245
   04620 Toll-like receptor signaling pathway
    104986245
   04625 C-type lectin receptor signaling pathway
    104986245
   04660 T cell receptor signaling pathway
    104986245
   04662 B cell receptor signaling pathway
    104986245
   04664 Fc epsilon RI signaling pathway
    104986245
   04666 Fc gamma R-mediated phagosome formation
    104986245
   04062 Chemokine signaling pathway
    104986245
  09152 Endocrine system
   04910 Insulin signaling pathway
    104986245
   04922 Glucagon signaling pathway
    104986245
   04923 Regulation of lipolysis in adipocytes
    104986245
   04920 Adipocytokine signaling pathway
    104986245
   04929 GnRH secretion
    104986245
   04915 Estrogen signaling pathway
    104986245
   04914 Progesterone-mediated oocyte maturation
    104986245
   04917 Prolactin signaling pathway
    104986245
   04926 Relaxin signaling pathway
    104986245
   04935 Growth hormone synthesis, secretion and action
    104986245
   04919 Thyroid hormone signaling pathway
    104986245
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    104986245
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    104986245
  09156 Nervous system
   04725 Cholinergic synapse
    104986245
   04728 Dopaminergic synapse
    104986245
   04722 Neurotrophin signaling pathway
    104986245
  09158 Development and regeneration
   04380 Osteoclast differentiation
    104986245
  09149 Aging
   04211 Longevity regulating pathway
    104986245
   04213 Longevity regulating pathway - multiple species
    104986245
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    104986245
   05205 Proteoglycans in cancer
    104986245
   05207 Chemical carcinogenesis - receptor activation
    104986245
   05208 Chemical carcinogenesis - reactive oxygen species
    104986245
   05230 Central carbon metabolism in cancer
    104986245
   05231 Choline metabolism in cancer
    104986245
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    104986245
  09162 Cancer: specific types
   05210 Colorectal cancer
    104986245
   05212 Pancreatic cancer
    104986245
   05225 Hepatocellular carcinoma
    104986245
   05226 Gastric cancer
    104986245
   05214 Glioma
    104986245
   05221 Acute myeloid leukemia
    104986245
   05220 Chronic myeloid leukemia
    104986245
   05218 Melanoma
    104986245
   05211 Renal cell carcinoma
    104986245
   05215 Prostate cancer
    104986245
   05213 Endometrial cancer
    104986245
   05224 Breast cancer
    104986245
   05222 Small cell lung cancer
    104986245
   05223 Non-small cell lung cancer
    104986245
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    104986245
   05170 Human immunodeficiency virus 1 infection
    104986245
   05161 Hepatitis B
    104986245
   05160 Hepatitis C
    104986245
   05164 Influenza A
    104986245
   05162 Measles
    104986245
   05168 Herpes simplex virus 1 infection
    104986245
   05163 Human cytomegalovirus infection
    104986245
   05167 Kaposi sarcoma-associated herpesvirus infection
    104986245
   05169 Epstein-Barr virus infection
    104986245
   05165 Human papillomavirus infection
    104986245
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    104986245
   05135 Yersinia infection
    104986245
   05152 Tuberculosis
    104986245
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    104986245
   05142 Chagas disease
    104986245
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    104986245
   05017 Spinocerebellar ataxia
    104986245
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    104986245
   05418 Fluid shear stress and atherosclerosis
    104986245
   05415 Diabetic cardiomyopathy
    104986245
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    104986245
   04932 Non-alcoholic fatty liver disease
    104986245
   04931 Insulin resistance
    104986245
   04933 AGE-RAGE signaling pathway in diabetic complications
    104986245
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    104986245
   01524 Platinum drug resistance
    104986245
   01522 Endocrine resistance
    104986245
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:bbis01001]
    104986245
Enzymes [BR:bbis01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     104986245
Protein kinases [BR:bbis01001]
 Serine/threonine kinases: AGC group
  AKT/PKB family
   104986245
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Pkinase_C Kinase-like ABC1 Seadorna_VP7
Other DBs
NCBI-GeneID: 104986245
NCBI-ProteinID: XP_010835024
UniProt: A0A6P3H7B2
LinkDB
Position
Unknown
AA seq 292 aa
DEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDR
TRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFC
GTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPR
TLSADAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVT
SETDTRYFDEEFTAQTITITPPEKYDEDGMDCMDNERRPHFPQFSYSASGRE
NT seq 879 nt   +upstreamnt  +downstreamnt
gatgaagtggcgcacactttaactgaaagcagagtattaaagaacactagacatcccttt
ttaacatccctgaaatattccttccagacaaaagaccgtttatgttttgtgatggaatat
gttaatgggggagagctgtttttccatttgtcgagagagcgggtgttctccgaggaccgc
acacgtttctatggtgcagaaattgtctctgccttggactatctacattccggaaagatt
gtgtaccgtgatctcaagttggagaatttgatgctggataaagatggccacataaaaatc
acagattttggactttgcaaagaagggatcactgatgcagccaccatgaagactttctgt
ggtacaccagagtatctggcaccagaggtgttagaagataatgactatggccgagctgtg
gattggtggggccttggggttgtcatgtatgaaatgatgtgcgggagattacctttctat
aaccaggatcatgagaaactttttgaactaattctaatggaagatattaaatttcctcga
acactctctgcagatgcaaaatcattgctttcaggcctcttgataaaggatccaaataaa
cgccttggtggaggaccagatgatgcaaaagaaattatgagacacagtttcttttctgga
gtaaactggcaagatgtgtatgataaaaagcttgtacctccttttaagcctcaagtaacg
tctgagacagacaccagatattttgatgaagaatttacagctcagactattacaataaca
ccacctgaaaaatatgatgaggacggtatggactgcatggacaatgagaggcggccgcac
ttccctcaattttcctactctgcaagtggacgagaataa

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