Bison bison bison (American bison): 104986737 Help Entry 104986737         CDS       T08726                                  Symbol PRKCB Name (RefSeq) protein kinase C beta type   KO K19662   classical protein kinase C beta type [EC:2.7.11.13] Organism bbis  Bison bison bison (American bison) Pathway bbis01521   EGFR tyrosine kinase inhibitor resistance bbis04010   MAPK signaling pathway bbis04012   ErbB signaling pathway bbis04014   Ras signaling pathway bbis04015   Rap1 signaling pathway bbis04020   Calcium signaling pathway bbis04062   Chemokine signaling pathway bbis04064   NF-kappa B signaling pathway bbis04066   HIF-1 signaling pathway bbis04070   Phosphatidylinositol signaling system bbis04071   Sphingolipid signaling pathway bbis04082   Neuroactive ligand signaling bbis04150   mTOR signaling pathway bbis04270   Vascular smooth muscle contraction bbis04310   Wnt signaling pathway bbis04370   VEGF signaling pathway bbis04510   Focal adhesion bbis04540   Gap junction bbis04613   Neutrophil extracellular trap formation bbis04650   Natural killer cell mediated cytotoxicity bbis04662   B cell receptor signaling pathway bbis04666   Fc gamma R-mediated phagocytosis bbis04670   Leukocyte transendothelial migration bbis04713   Circadian entrainment bbis04720   Long-term potentiation bbis04723   Retrograde endocannabinoid signaling bbis04724   Glutamatergic synapse bbis04725   Cholinergic synapse bbis04726   Serotonergic synapse bbis04727   GABAergic synapse bbis04728   Dopaminergic synapse bbis04730   Long-term depression bbis04750   Inflammatory mediator regulation of TRP channels bbis04911   Insulin secretion bbis04912   GnRH signaling pathway bbis04916   Melanogenesis bbis04918   Thyroid hormone synthesis bbis04919   Thyroid hormone signaling pathway bbis04921   Oxytocin signaling pathway bbis04925   Aldosterone synthesis and secretion bbis04928   Parathyroid hormone synthesis, secretion and action bbis04929   GnRH secretion bbis04931   Insulin resistance bbis04933   AGE-RAGE signaling pathway in diabetic complications bbis04935   Growth hormone synthesis, secretion and action bbis04960   Aldosterone-regulated sodium reabsorption bbis04961   Endocrine and other factor-regulated calcium reabsorption bbis04970   Salivary secretion bbis04971   Gastric acid secretion bbis04972   Pancreatic secretion bbis04973   Carbohydrate digestion and absorption bbis05017   Spinocerebellar ataxia bbis05022   Pathways of neurodegeneration - multiple diseases bbis05031   Amphetamine addiction bbis05032   Morphine addiction bbis05140   Leishmaniasis bbis05143   African trypanosomiasis bbis05146   Amoebiasis bbis05161   Hepatitis B bbis05163   Human cytomegalovirus infection bbis05164   Influenza A bbis05170   Human immunodeficiency virus 1 infection bbis05171   Coronavirus disease - COVID-19 bbis05200   Pathways in cancer bbis05205   Proteoglycans in cancer bbis05206   MicroRNAs in cancer bbis05207   Chemical carcinogenesis - receptor activation bbis05214   Glioma bbis05223   Non-small cell lung cancer bbis05225   Hepatocellular carcinoma bbis05231   Choline metabolism in cancer bbis05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:bbis00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     104986737 (PRKCB)    04012 ErbB signaling pathway     104986737 (PRKCB)    04014 Ras signaling pathway     104986737 (PRKCB)    04015 Rap1 signaling pathway     104986737 (PRKCB)    04310 Wnt signaling pathway     104986737 (PRKCB)    04370 VEGF signaling pathway     104986737 (PRKCB)    04064 NF-kappa B signaling pathway     104986737 (PRKCB)    04066 HIF-1 signaling pathway     104986737 (PRKCB)    04020 Calcium signaling pathway     104986737 (PRKCB)    04070 Phosphatidylinositol signaling system     104986737 (PRKCB)    04071 Sphingolipid signaling pathway     104986737 (PRKCB)    04150 mTOR signaling pathway     104986737 (PRKCB)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     104986737 (PRKCB)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     104986737 (PRKCB)    04540 Gap junction     104986737 (PRKCB)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     104986737 (PRKCB)    04650 Natural killer cell mediated cytotoxicity     104986737 (PRKCB)    04662 B cell receptor signaling pathway     104986737 (PRKCB)    04666 Fc gamma R-mediated phagocytosis     104986737 (PRKCB)    04670 Leukocyte transendothelial migration     104986737 (PRKCB)    04062 Chemokine signaling pathway     104986737 (PRKCB)   09152 Endocrine system    04911 Insulin secretion     104986737 (PRKCB)    04929 GnRH secretion     104986737 (PRKCB)    04912 GnRH signaling pathway     104986737 (PRKCB)    04921 Oxytocin signaling pathway     104986737 (PRKCB)    04935 Growth hormone synthesis, secretion and action     104986737 (PRKCB)    04918 Thyroid hormone synthesis     104986737 (PRKCB)    04919 Thyroid hormone signaling pathway     104986737 (PRKCB)    04928 Parathyroid hormone synthesis, secretion and action     104986737 (PRKCB)    04916 Melanogenesis     104986737 (PRKCB)    04925 Aldosterone synthesis and secretion     104986737 (PRKCB)   09153 Circulatory system    04270 Vascular smooth muscle contraction     104986737 (PRKCB)   09154 Digestive system    04970 Salivary secretion     104986737 (PRKCB)    04971 Gastric acid secretion     104986737 (PRKCB)    04972 Pancreatic secretion     104986737 (PRKCB)    04973 Carbohydrate digestion and absorption     104986737 (PRKCB)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     104986737 (PRKCB)    04961 Endocrine and other factor-regulated calcium reabsorption     104986737 (PRKCB)   09156 Nervous system    04724 Glutamatergic synapse     104986737 (PRKCB)    04727 GABAergic synapse     104986737 (PRKCB)    04725 Cholinergic synapse     104986737 (PRKCB)    04728 Dopaminergic synapse     104986737 (PRKCB)    04726 Serotonergic synapse     104986737 (PRKCB)    04720 Long-term potentiation     104986737 (PRKCB)    04730 Long-term depression     104986737 (PRKCB)    04723 Retrograde endocannabinoid signaling     104986737 (PRKCB)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     104986737 (PRKCB)   09159 Environmental adaptation    04713 Circadian entrainment     104986737 (PRKCB)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     104986737 (PRKCB)    05206 MicroRNAs in cancer     104986737 (PRKCB)    05205 Proteoglycans in cancer     104986737 (PRKCB)    05207 Chemical carcinogenesis - receptor activation     104986737 (PRKCB)    05231 Choline metabolism in cancer     104986737 (PRKCB)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     104986737 (PRKCB)    05214 Glioma     104986737 (PRKCB)    05223 Non-small cell lung cancer     104986737 (PRKCB)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     104986737 (PRKCB)    05161 Hepatitis B     104986737 (PRKCB)    05171 Coronavirus disease - COVID-19     104986737 (PRKCB)    05164 Influenza A     104986737 (PRKCB)    05163 Human cytomegalovirus infection     104986737 (PRKCB)   09174 Infectious disease: parasitic    05146 Amoebiasis     104986737 (PRKCB)    05140 Leishmaniasis     104986737 (PRKCB)    05143 African trypanosomiasis     104986737 (PRKCB)   09164 Neurodegenerative disease    05017 Spinocerebellar ataxia     104986737 (PRKCB)    05022 Pathways of neurodegeneration - multiple diseases     104986737 (PRKCB)   09165 Substance dependence    05031 Amphetamine addiction     104986737 (PRKCB)    05032 Morphine addiction     104986737 (PRKCB)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     104986737 (PRKCB)   09167 Endocrine and metabolic disease    04931 Insulin resistance     104986737 (PRKCB)    04933 AGE-RAGE signaling pathway in diabetic complications     104986737 (PRKCB)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     104986737 (PRKCB)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:bbis01001]     104986737 (PRKCB) Enzymes [BR:bbis01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.13  protein kinase C      104986737 (PRKCB) Protein kinases [BR:bbis01001]  Serine/threonine kinases: AGC group   PKC family [OT]    104986737 (PRKCB) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr C1_1 C2 Pkinase_C Kinase-like ABC1 CEP76-C2 C1_2 Motif Other DBs NCBI-GeneID:  104986737 NCBI-ProteinID:  XP_010835724 UniProt:  A0A6P3H9F1 LinkDB All DBs Position Unknown AA seq 772 aa AA seqDB search MAAPELLTVLADLQGSTVAFSIITSSLVKEHGQPCEPRGFGEAKGDPELPEELQAWPLPH TNEMNQQRHCNMCAYRLLAIQAEDRVGGARRGGAEAQVWRLQTAVLGAAAALRLRTLRWE AGSLGVLISGASGAKRSWTNSGSWQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEF VTFSCPGADKGPASDDPRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHK RCVMNVPSLCGTDHTERRGRIYIQAHIEREVLIVVVRDAKNLVPMDPNGLSDPYVKLKLI PDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRLSVEIWDWDLTSRNDFMGSLSF GISELQKAGVDGWFKLLSQEEGEYFNVPVPPEGSEGNEELRQKFERAKIGPGPKTPEEKT TNTISKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQD DDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEP HAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTF CGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYP KSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKA CGRNAENFDRFFTRHPPVLTPPDQEVIRNIDQSEFEGFSFVNSEFLKPEVKS NT seq 2319 nt NT seq  +upstreamnt  +downstreamnt atggctgcaccagagcttcttactgtccttgctgacctccaggggtcaacagtagcattc tccatcatcacttccagtttagtgaaggagcatgggcagccctgtgagccaagaggattt ggagaagccaaaggagacccagagttgccagaggagctgcaggcctggccgctgccccac accaacgagatgaaccagcagagacactgcaatatgtgtgcttatcgccttcttgcaatt caggccgaggacagggtcgggggtgcgcggcgcgggggggccgaggctcaggtctggcgg ttgcagactgcggtcctcggtgccgccgcagcactgcggctgagaacgcttcgctgggag gccggcagcctcggggtgctaatatctggggccagcggtgccaagcgcagctggactaac agcggcagctggcagcccaccttctgcagccactgcaccgacttcatctggggcttcggg aagcaaggatttcagtgccaagtctgctgttttgtcgtgcacaagcggtgccatgaattt gtcaccttctcctgcccgggcgctgacaagggcccagcctccgacgacccccggagcaaa cacaagttcaagatccacacatactccagccccacgttttgtgaccactgcgggtcattg ctctatggacttatccaccaggggatgaaatgtgacacctgcatgatgaacgtccacaag cgctgcgtgatgaacgtccccagcctctgcggcacggaccacacggagcgccgcggccgc atctacatccaagcccacatcgagagggaggtcctcattgttgtcgtaagagatgctaaa aaccttgtacctatggatcctaatggcttgtcagatccttacgtgaaactgaaactgatt cctgatcccaagagtgagagcaagcagaagaccaagaccatcaagtgctccctcaacccc gagtggaacgaaacatttagattccagctgaaagaatcggacaaagacaggagactgtct gtagagatttgggattgggatctgaccagcagaaatgacttcatgggatctttgtcgttt gggatttctgaactgcagaaagctggtgttgatggctggtttaagttactgagccaggag gaaggcgagtacttcaacgtgcccgtgccaccggaaggcagtgagggcaacgaggaactg cgacagaaattcgagagagccaagatcggtcctgggcccaagactcctgaagaaaagacg accaacaccatctccaaatttgacaacaacggcaacagggaccggatgaaactgaccgat tttaacttcctgatggtgctgggaaaaggcagctttggcaaggtcatgctctcagagcga aaaggcacagatgagctgtatgctgtgaagatcctgaaaaaggacgtggtcatccaagat gatgacgtggaatgcacgatggtggagaagcgggtgctggccctgcccgggaagccgccc ttcctgacccagctgcattcctgcttccagaccatggatcgcctgtacttcgtgatggag tatgtgaacggcggtgacctcatgtaccacatccagcaagtgggccggttcaaggagcct cacgccgtattttacgctgcagaaattgccatcggtctgttcttcttgcagagcaagggc atcatttaccgtgacctgaaacttgacaatgtgatgctggattccgagggccacatcaag attgctgattttggcatgtgtaaggagaacatctgggatggggtgacaactaagaccttc tgcggcaccccagactacatcgcccccgagataattgcttatcagccctatgggaagtcc gtggattggtgggcatttggcgtcctgctgtatgagatgttggctgggcaggcaccgttt gaaggggaggacgaggatgaactcttccagtccatcatggaacacaacgtggcttatccg aagtccatgtccaaggaagctgtggccatctgcaaagggctgatgaccaaacacccaggc aaacgtctgggttgtggacctgaaggtgaacgtgacatcaaagagcatgcatttttccgg tatattgactgggagaaacttgaacgcaaagagattcagcccccatataagccgaaagcc tgtgggcgaaatgctgaaaacttcgaccgatttttcacccgccatccaccagttctaaca cctcctgaccaggaagtcatcaggaatattgaccaatcagaattcgaaggattttccttt gttaactctgaatttttaaaacctgaagtcaagagctaa

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