KEGG   Bison bison bison (American bison): 104987069
Entry
104987069         CDS       T08726                                 
Symbol
PPP1CA
Name
(RefSeq) serine/threonine-protein phosphatase PP1-alpha catalytic subunit
  KO
K06269  serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
Organism
bbis  Bison bison bison (American bison)
Pathway
bbis03015  mRNA surveillance pathway
bbis04022  cGMP-PKG signaling pathway
bbis04024  cAMP signaling pathway
bbis04114  Oocyte meiosis
bbis04218  Cellular senescence
bbis04261  Adrenergic signaling in cardiomyocytes
bbis04270  Vascular smooth muscle contraction
bbis04390  Hippo signaling pathway
bbis04510  Focal adhesion
bbis04611  Platelet activation
bbis04720  Long-term potentiation
bbis04728  Dopaminergic synapse
bbis04750  Inflammatory mediator regulation of TRP channels
bbis04810  Regulation of actin cytoskeleton
bbis04910  Insulin signaling pathway
bbis04921  Oxytocin signaling pathway
bbis04931  Insulin resistance
bbis05031  Amphetamine addiction
bbis05034  Alcoholism
bbis05168  Herpes simplex virus 1 infection
bbis05205  Proteoglycans in cancer
bbis05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:bbis00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    104987069 (PPP1CA)
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    104987069 (PPP1CA)
   04024 cAMP signaling pathway
    104987069 (PPP1CA)
   04022 cGMP-PKG signaling pathway
    104987069 (PPP1CA)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    104987069 (PPP1CA)
   04218 Cellular senescence
    104987069 (PPP1CA)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    104987069 (PPP1CA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    104987069 (PPP1CA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    104987069 (PPP1CA)
  09152 Endocrine system
   04910 Insulin signaling pathway
    104987069 (PPP1CA)
   04921 Oxytocin signaling pathway
    104987069 (PPP1CA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    104987069 (PPP1CA)
   04270 Vascular smooth muscle contraction
    104987069 (PPP1CA)
  09156 Nervous system
   04728 Dopaminergic synapse
    104987069 (PPP1CA)
   04720 Long-term potentiation
    104987069 (PPP1CA)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    104987069 (PPP1CA)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    104987069 (PPP1CA)
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    104987069 (PPP1CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    104987069 (PPP1CA)
   05034 Alcoholism
    104987069 (PPP1CA)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    104987069 (PPP1CA)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    104987069 (PPP1CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:bbis01009]
    104987069 (PPP1CA)
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:bbis03021]
    104987069 (PPP1CA)
   03019 Messenger RNA biogenesis [BR:bbis03019]
    104987069 (PPP1CA)
   03041 Spliceosome [BR:bbis03041]
    104987069 (PPP1CA)
Enzymes [BR:bbis01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     104987069 (PPP1CA)
Protein phosphatases and associated proteins [BR:bbis01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    Catalytic subunits
     104987069 (PPP1CA)
Transcription machinery [BR:bbis03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     104987069 (PPP1CA)
Messenger RNA biogenesis [BR:bbis03019]
 Eukaryotic type
  mRNA processing factors
   3' end processing
    Cleavage and polyadenylation specificity factor (CPSF) complex
     104987069 (PPP1CA)
Spliceosome [BR:bbis03041]
 Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    104987069 (PPP1CA)
SSDB
Motif
Pfam: Metallophos STPPase_N
Other DBs
NCBI-GeneID: 104987069
NCBI-ProteinID: XP_010836132
UniProt: A0A6P3H9Z8
LinkDB
Position
Unknown
AA seq 398 aa
MHTEQRGSVPTPRLPWLGTSCDGIYPVDTERKIRVKLWQPWDSAGLGASRLAGQSCSVYA
RRAWRSPEAELSQEETEAQREKFLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPIL
LELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKI
KYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCC
HGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVV
AKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCS
FQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK
NT seq 1197 nt   +upstreamnt  +downstreamnt
atgcacacagagcagcgtggttctgtgcccacccccagactgccctggctgggcaccagc
tgtgatggcatctaccctgtggacacagagaggaaaatcagggtcaagctatggcagccc
tgggactcggcggggctgggggcaagcaggctggcagggcagtcttgctctgtctacgcc
aggagagcctggaggtcacccgaggccgagctgagccaggaggaaacggaggctcagaga
gaaaaattcctgctggaagtgcagggctccaggcctggaaagaatgtacagctgacggag
aacgagatccgtggtctgtgcctcaaatcccgggagattttcctgagccagcccattctt
ctggagctggaggcacccctcaagatctgcggtgacattcacggccagtactatgatctt
ctgcggctgttcgagtacggtggcttccctccagagagtaactacttgttcctgggggac
tacgtggacaggggcaagcagtctttggagaccatctgcttgctgctggcctataagatc
aagtacccagagaacttcttcctgctccgtgggaaccacgagtgtgccagcatcaaccgc
atctacggcttctatgatgagtgcaagagacgctacaacatcaaactgtggaagaccttc
actgattgcttcaactgcctgcccatcgctgccatcgtggacgagaagatcttctgttgc
catggaggcctgtccccagacctacagtccatggagcagatccggcgtatcatgcggccc
acagatgtgcctgaccagggcctgctctgtgacctgctgtggtctgaccctgacaaggac
gtgcagggctggggcgagaatgaccgcggcgtctcctttacatttggagctgaggtggtg
gccaagttcctgcacaagcatgacctggacctcatctgccgggcacaccaggtagtagaa
gacggctatgagttctttgccaagcggcagctggtgacactcttctcagcccccaactac
tgcggcgagtttgacaatgcaggtgccatgatgagtgtggacgagacgctcatgtgctcc
ttccagatcctcaagcccgctgacaagaacaaggggaaatacgggcagttcagtggcctg
aaccctggaggccggcccatcaccccaccccgcaactccgccaaagccaagaaatag

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