Bison bison bison (American bison): 104987400 Help Entry 104987400         CDS       T08726                                  Symbol PKLR Name (RefSeq) pyruvate kinase PKLR isoform X1   KO K12406   pyruvate kinase isozymes R/L [EC:2.7.1.40] Organism bbis  Bison bison bison (American bison) Pathway bbis00010   Glycolysis / Gluconeogenesis bbis00620   Pyruvate metabolism bbis01100   Metabolic pathways bbis01200   Carbon metabolism bbis01230   Biosynthesis of amino acids bbis04910   Insulin signaling pathway bbis04930   Type II diabetes mellitus bbis04932   Non-alcoholic fatty liver disease bbis04950   Maturity onset diabetes of the young Module bbis_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate bbis_M00002   Glycolysis, core module involving three-carbon compounds Brite KEGG Orthology (KO) [BR:bbis00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     104987400 (PKLR)    00620 Pyruvate metabolism     104987400 (PKLR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     104987400 (PKLR)  09160 Human Diseases   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     104987400 (PKLR)    04950 Maturity onset diabetes of the young     104987400 (PKLR)    04932 Non-alcoholic fatty liver disease     104987400 (PKLR)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:bbis04147]     104987400 (PKLR) Enzymes [BR:bbis01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.40  pyruvate kinase      104987400 (PKLR) Exosome [BR:bbis04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    104987400 (PKLR) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK PK_C IMPDH HpcH_HpaI Neuregulin Motif Other DBs NCBI-GeneID:  104987400 NCBI-ProteinID:  XP_010836586 Ensembl:  ENSBBBG00000014928 UniProt:  A0A6P3H3G2 LinkDB All DBs Position Unknown AA seq 528 aa AA seqDB search MTQELGISFFQRQQLPAAMADTFLEHLCLLDIDSEPVVARSTSIIATIGPASRSVERLKE MIEAGMNIARLNFSHGSHEYHAESIANIREAVESFANSPLSYRPVAIALDTKGPEIRTGI LQGDPASEVEIVKGSRVLVTVDPEFQTRGDANTVWVDYPNIVRVMPVGGRIYIDDGLISL VVKKIGPEGLETEVENGGVLGSRKGVNLPGIQVDLPGLSEQDVQDLRFGVEHGVDIVFVS FVRKASDVAAVRDALGPEGQGIKIVSKIENHEGVKKFNEILEVSDGIMVARGDLGIEIPA EKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSG ETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKC CAGAIIVLTTTGRSAQLLSRYRPRATVIAVTRSAQAARQAHLCRGVFPVLYREPPEDIWA DDVDRRVQFGIDNGKLCGFLSSGDLVIVVTGWQPGSGHTNIMRVLSVT NT seq 1587 nt NT seq  +upstreamnt  +downstreamnt atgactcaggagctgggcatttccttcttccagcggcagcagctgccagccgctatggca gacaccttcctggaacatctgtgcctgctggacattgactctgagcctgtggtcgctcgc agtaccagtatcatcgccaccatcgggccggcatctcgctccgtggagcgtctcaaggag atgatcgaggccgggatgaacatcgcgagactcaacttctcccacggctcccacgagtac cacgctgagtccatcgctaacatccgggaggcggtggagagctttgcaaattctccgctc agctaccgacccgtggccatcgccctggacaccaagggaccagagatacgcactgggatc ctgcaaggggacccggcgtcagaagtggagatagtgaagggctcccgggtgctggtgacc gtggacccagagttccagacccgcggggacgcgaacaccgtgtgggtggactaccccaat atcgtccgagtcatgccggtggggggccgcatctacattgacgacgggctcatctcccta gtggtcaagaaaatcggtccagaagggctagagaccgaagtggagaacggcggggtcctg ggcagtcggaagggcgtgaacttgccaggcatccaggtggacctgcccgggctgtccgag caagatgtccaggacctgcgcttcggggtggagcatggcgtggacatcgtctttgtctct ttcgtgcggaaagccagcgacgtggctgccgtccgggatgctctggggccggaaggacag ggcatcaagatcgttagcaaaatcgagaaccacgagggcgtaaagaagttcaatgaaatc ctggaggtgagcgacggtattatggtggcacggggtgacctgggcattgagatcccggct gagaaggttttcctggctcagaagatgatgatcggccgttgcaacttggcgggaaagccc gttgtctgtgctacacagatgctggagagcatgatcactaagccccggccaactcgggca gagacaagtgacgtggccaatgctgttctggatggggcagactgcatcatgctgtcaggg gagactgccaaaggcaactttcctgtggaggctgtaaagatgcagcatgcgattgcccgg gaggcagaggctgccgtgtaccaccggcagctctttgaggagctacgccgggcagcacca ctgagccgggatcccacggaggtcaccgctattggtgctgtggaggctgccttcaagtgc tgtgctggtgccatcattgtgctgaccacaactggccgctcagcccagcttctgtcccgg taccgacctcgggcaacagtcattgccgtcacccgctctgctcaggctgcccgccaggcc cacctgtgccgaggagtcttccctgtgctctaccgtgaacctccagaggacatctgggcc gatgatgtggaccgtcgggtccaatttggcatcgacaatggaaagctctgtggcttcctc agttctggggacctggtgattgtggtgacaggctggcaaccaggctccggccataccaac atcatgcgggtgctgagcgtaacctga

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