KEGG   Bison bison bison (American bison): 104988453
Entry
104988453         CDS       T08726                                 
Symbol
CDK6
Name
(RefSeq) cyclin-dependent kinase 6
  KO
K02091  cyclin-dependent kinase 6 [EC:2.7.11.22]
Organism
bbis  Bison bison bison (American bison)
Pathway
bbis04110  Cell cycle
bbis04115  p53 signaling pathway
bbis04151  PI3K-Akt signaling pathway
bbis04218  Cellular senescence
bbis04934  Cushing syndrome
bbis05160  Hepatitis C
bbis05162  Measles
bbis05163  Human cytomegalovirus infection
bbis05164  Influenza A
bbis05165  Human papillomavirus infection
bbis05167  Kaposi sarcoma-associated herpesvirus infection
bbis05169  Epstein-Barr virus infection
bbis05200  Pathways in cancer
bbis05203  Viral carcinogenesis
bbis05206  MicroRNAs in cancer
bbis05212  Pancreatic cancer
bbis05214  Glioma
bbis05218  Melanoma
bbis05220  Chronic myeloid leukemia
bbis05222  Small cell lung cancer
bbis05223  Non-small cell lung cancer
bbis05224  Breast cancer
bbis05225  Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:bbis00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    104988453 (CDK6)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    104988453 (CDK6)
   04115 p53 signaling pathway
    104988453 (CDK6)
   04218 Cellular senescence
    104988453 (CDK6)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    104988453 (CDK6)
   05206 MicroRNAs in cancer
    104988453 (CDK6)
   05203 Viral carcinogenesis
    104988453 (CDK6)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    104988453 (CDK6)
   05225 Hepatocellular carcinoma
    104988453 (CDK6)
   05214 Glioma
    104988453 (CDK6)
   05220 Chronic myeloid leukemia
    104988453 (CDK6)
   05218 Melanoma
    104988453 (CDK6)
   05224 Breast cancer
    104988453 (CDK6)
   05222 Small cell lung cancer
    104988453 (CDK6)
   05223 Non-small cell lung cancer
    104988453 (CDK6)
  09172 Infectious disease: viral
   05160 Hepatitis C
    104988453 (CDK6)
   05164 Influenza A
    104988453 (CDK6)
   05162 Measles
    104988453 (CDK6)
   05163 Human cytomegalovirus infection
    104988453 (CDK6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    104988453 (CDK6)
   05169 Epstein-Barr virus infection
    104988453 (CDK6)
   05165 Human papillomavirus infection
    104988453 (CDK6)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    104988453 (CDK6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:bbis01001]
    104988453 (CDK6)
Enzymes [BR:bbis01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     104988453 (CDK6)
Protein kinases [BR:bbis01001]
 Serine/threonine kinases: CMGC group
  CDK family
   104988453 (CDK6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH Haspin_kinase RIO1 Kinase-like FTA2 Uricase
Other DBs
NCBI-GeneID: 104988453
NCBI-ProteinID: XP_010838086
Ensembl: ENSBBBG00000018101
UniProt: A0A6P3HFF8
LinkDB
Position
Unknown
AA seq 326 aa
MEKDGLSRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR
EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTE
TIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVV
VTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGE
EDWPRDVALPRQAFHSKSPQPIEKFVTDIDEQGKDLLLKCLTFNPAKRISAYSALSHPYF
HDLERRKENLDSHLPPSQNSSEMNTA
NT seq 981 nt   +upstreamnt  +downstreamnt
atggagaaggacggcctgagccgtgccgaccagcagtatgagtgcgtggcggagatcggg
gagggcgcctacgggaaggtgttcaaggcccgggacctgaagaacggaggccgtttcgtg
gcgctgaagcgcgtgcgagtgcagactggcgaggagggcatgccgctctccaccatccgc
gaggtggcggtgctgaggcacctggagaccttcgagcaccccaacgtggtcaggttgttt
gacgtgtgtacagtgtcacgaacagacagagaaaccaaactaacgttagtgtttgaacac
gttgatcaagacttgaccacttatttggataaagtgccagaacctggagtgcccactgaa
accataaaggatatgatgtttcagcttctccgaggcctggactttcttcattctcaccga
gtggtgcatcgtgatctaaaaccacagaacattctggtgaccagcagtggacaaataaag
ctggctgacttcggccttgctcgcatctacagttttcagatggctcttacctcagtggtc
gtcacgctgtggtaccgagctccagaagtcctgcttcagtccagctacgccacccctgtg
gatctctggagcgttggctgcatctttgcagagatgtttcgtagaaagccgctttttcgt
ggaagttcagatgtcgaccaactaggaaaaatcttggacgtaattggactcccgggagaa
gaggactggcctagagatgttgccctacccaggcaggcttttcactcaaaatcccctcaa
ccaattgagaagtttgtaacagacattgatgaacaaggcaaagacctgcttctgaagtgc
ttgacatttaatccagccaaaagaatatcagcatacagtgccctgtctcacccatacttc
cacgatctggagaggcgcaaggaaaacctggattcccacctgccgcccagccagaacagc
tcggaaatgaataccgcttaa

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