Bison bison bison (American bison): 104989637
Help
Entry
104989637 CDS
T08726
Name
(RefSeq) RAC-alpha serine/threonine-protein kinase-like
KO
K04456
RAC serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
bbis
Bison bison bison (American bison)
Pathway
bbis01521
EGFR tyrosine kinase inhibitor resistance
bbis01522
Endocrine resistance
bbis01524
Platinum drug resistance
bbis04010
MAPK signaling pathway
bbis04012
ErbB signaling pathway
bbis04014
Ras signaling pathway
bbis04015
Rap1 signaling pathway
bbis04022
cGMP-PKG signaling pathway
bbis04024
cAMP signaling pathway
bbis04062
Chemokine signaling pathway
bbis04066
HIF-1 signaling pathway
bbis04068
FoxO signaling pathway
bbis04071
Sphingolipid signaling pathway
bbis04072
Phospholipase D signaling pathway
bbis04140
Autophagy - animal
bbis04150
mTOR signaling pathway
bbis04151
PI3K-Akt signaling pathway
bbis04152
AMPK signaling pathway
bbis04210
Apoptosis
bbis04211
Longevity regulating pathway
bbis04213
Longevity regulating pathway - multiple species
bbis04218
Cellular senescence
bbis04261
Adrenergic signaling in cardiomyocytes
bbis04370
VEGF signaling pathway
bbis04371
Apelin signaling pathway
bbis04380
Osteoclast differentiation
bbis04510
Focal adhesion
bbis04517
IgSF CAM signaling
bbis04550
Signaling pathways regulating pluripotency of stem cells
bbis04611
Platelet activation
bbis04613
Neutrophil extracellular trap formation
bbis04620
Toll-like receptor signaling pathway
bbis04625
C-type lectin receptor signaling pathway
bbis04630
JAK-STAT signaling pathway
bbis04660
T cell receptor signaling pathway
bbis04662
B cell receptor signaling pathway
bbis04664
Fc epsilon RI signaling pathway
bbis04666
Fc gamma R-mediated phagocytosis
bbis04668
TNF signaling pathway
bbis04722
Neurotrophin signaling pathway
bbis04725
Cholinergic synapse
bbis04728
Dopaminergic synapse
bbis04810
Regulation of actin cytoskeleton
bbis04910
Insulin signaling pathway
bbis04914
Progesterone-mediated oocyte maturation
bbis04915
Estrogen signaling pathway
bbis04917
Prolactin signaling pathway
bbis04919
Thyroid hormone signaling pathway
bbis04920
Adipocytokine signaling pathway
bbis04922
Glucagon signaling pathway
bbis04923
Regulation of lipolysis in adipocytes
bbis04926
Relaxin signaling pathway
bbis04929
GnRH secretion
bbis04931
Insulin resistance
bbis04932
Non-alcoholic fatty liver disease
bbis04933
AGE-RAGE signaling pathway in diabetic complications
bbis04935
Growth hormone synthesis, secretion and action
bbis04936
Alcoholic liver disease
bbis04973
Carbohydrate digestion and absorption
bbis05010
Alzheimer disease
bbis05017
Spinocerebellar ataxia
bbis05132
Salmonella infection
bbis05135
Yersinia infection
bbis05142
Chagas disease
bbis05145
Toxoplasmosis
bbis05152
Tuberculosis
bbis05160
Hepatitis C
bbis05161
Hepatitis B
bbis05162
Measles
bbis05163
Human cytomegalovirus infection
bbis05164
Influenza A
bbis05165
Human papillomavirus infection
bbis05166
Human T-cell leukemia virus 1 infection
bbis05167
Kaposi sarcoma-associated herpesvirus infection
bbis05168
Herpes simplex virus 1 infection
bbis05169
Epstein-Barr virus infection
bbis05170
Human immunodeficiency virus 1 infection
bbis05200
Pathways in cancer
bbis05205
Proteoglycans in cancer
bbis05207
Chemical carcinogenesis - receptor activation
bbis05208
Chemical carcinogenesis - reactive oxygen species
bbis05210
Colorectal cancer
bbis05211
Renal cell carcinoma
bbis05212
Pancreatic cancer
bbis05213
Endometrial cancer
bbis05214
Glioma
bbis05215
Prostate cancer
bbis05218
Melanoma
bbis05220
Chronic myeloid leukemia
bbis05221
Acute myeloid leukemia
bbis05222
Small cell lung cancer
bbis05223
Non-small cell lung cancer
bbis05224
Breast cancer
bbis05225
Hepatocellular carcinoma
bbis05226
Gastric cancer
bbis05230
Central carbon metabolism in cancer
bbis05231
Choline metabolism in cancer
bbis05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
bbis05415
Diabetic cardiomyopathy
bbis05417
Lipid and atherosclerosis
bbis05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
bbis00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
104989637
04012 ErbB signaling pathway
104989637
04014 Ras signaling pathway
104989637
04015 Rap1 signaling pathway
104989637
04370 VEGF signaling pathway
104989637
04371 Apelin signaling pathway
104989637
04630 JAK-STAT signaling pathway
104989637
04668 TNF signaling pathway
104989637
04066 HIF-1 signaling pathway
104989637
04068 FoxO signaling pathway
104989637
04072 Phospholipase D signaling pathway
104989637
04071 Sphingolipid signaling pathway
104989637
04024 cAMP signaling pathway
104989637
04022 cGMP-PKG signaling pathway
104989637
04151 PI3K-Akt signaling pathway
104989637
04152 AMPK signaling pathway
104989637
04150 mTOR signaling pathway
104989637
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
104989637
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
104989637
09143 Cell growth and death
04210 Apoptosis
104989637
04218 Cellular senescence
104989637
09144 Cellular community - eukaryotes
04510 Focal adhesion
104989637
04550 Signaling pathways regulating pluripotency of stem cells
104989637
09142 Cell motility
04810 Regulation of actin cytoskeleton
104989637
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
104989637
04613 Neutrophil extracellular trap formation
104989637
04620 Toll-like receptor signaling pathway
104989637
04625 C-type lectin receptor signaling pathway
104989637
04660 T cell receptor signaling pathway
104989637
04662 B cell receptor signaling pathway
104989637
04664 Fc epsilon RI signaling pathway
104989637
04666 Fc gamma R-mediated phagocytosis
104989637
04062 Chemokine signaling pathway
104989637
09152 Endocrine system
04910 Insulin signaling pathway
104989637
04922 Glucagon signaling pathway
104989637
04923 Regulation of lipolysis in adipocytes
104989637
04920 Adipocytokine signaling pathway
104989637
04929 GnRH secretion
104989637
04915 Estrogen signaling pathway
104989637
04914 Progesterone-mediated oocyte maturation
104989637
04917 Prolactin signaling pathway
104989637
04926 Relaxin signaling pathway
104989637
04935 Growth hormone synthesis, secretion and action
104989637
04919 Thyroid hormone signaling pathway
104989637
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
104989637
09154 Digestive system
04973 Carbohydrate digestion and absorption
104989637
09156 Nervous system
04725 Cholinergic synapse
104989637
04728 Dopaminergic synapse
104989637
04722 Neurotrophin signaling pathway
104989637
09158 Development and regeneration
04380 Osteoclast differentiation
104989637
09149 Aging
04211 Longevity regulating pathway
104989637
04213 Longevity regulating pathway - multiple species
104989637
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
104989637
05205 Proteoglycans in cancer
104989637
05207 Chemical carcinogenesis - receptor activation
104989637
05208 Chemical carcinogenesis - reactive oxygen species
104989637
05230 Central carbon metabolism in cancer
104989637
05231 Choline metabolism in cancer
104989637
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
104989637
09162 Cancer: specific types
05210 Colorectal cancer
104989637
05212 Pancreatic cancer
104989637
05225 Hepatocellular carcinoma
104989637
05226 Gastric cancer
104989637
05214 Glioma
104989637
05221 Acute myeloid leukemia
104989637
05220 Chronic myeloid leukemia
104989637
05218 Melanoma
104989637
05211 Renal cell carcinoma
104989637
05215 Prostate cancer
104989637
05213 Endometrial cancer
104989637
05224 Breast cancer
104989637
05222 Small cell lung cancer
104989637
05223 Non-small cell lung cancer
104989637
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
104989637
05170 Human immunodeficiency virus 1 infection
104989637
05161 Hepatitis B
104989637
05160 Hepatitis C
104989637
05164 Influenza A
104989637
05162 Measles
104989637
05168 Herpes simplex virus 1 infection
104989637
05163 Human cytomegalovirus infection
104989637
05167 Kaposi sarcoma-associated herpesvirus infection
104989637
05169 Epstein-Barr virus infection
104989637
05165 Human papillomavirus infection
104989637
09171 Infectious disease: bacterial
05132 Salmonella infection
104989637
05135 Yersinia infection
104989637
05152 Tuberculosis
104989637
09174 Infectious disease: parasitic
05145 Toxoplasmosis
104989637
05142 Chagas disease
104989637
09164 Neurodegenerative disease
05010 Alzheimer disease
104989637
05017 Spinocerebellar ataxia
104989637
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
104989637
05418 Fluid shear stress and atherosclerosis
104989637
05415 Diabetic cardiomyopathy
104989637
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
104989637
04932 Non-alcoholic fatty liver disease
104989637
04931 Insulin resistance
104989637
04933 AGE-RAGE signaling pathway in diabetic complications
104989637
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
104989637
01524 Platinum drug resistance
104989637
01522 Endocrine resistance
104989637
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
bbis01001
]
104989637
Enzymes [BR:
bbis01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
104989637
Protein kinases [BR:
bbis01001
]
Serine/threonine kinases: AGC group
AKT/PKB family
104989637
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PH
PK_Tyr_Ser-Thr
Pkinase_C
PH_20
Kinase-like
PH_11
DUF4219
Motif
Other DBs
NCBI-GeneID:
104989637
NCBI-ProteinID:
XP_010839682
UniProt:
A0A6P3HJT2
LinkDB
All DBs
Position
Unknown
AA seq
493 aa
AA seq
DB search
MNDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDLEQRESPLNNFSVAQC
QLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKRQEEETMDF
RSGSPGENSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKI
LKKEVIVAKRIVRRRPGFVTPSTGSEAACGLKRESSDHVSTWSLDLQLLVLRRGLWDSGG
PPLHRADPCPAQGQVPALLPSQALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFPEDR
ARFYGAEIVSALDYLHSEKNVVYRDLKVGEAGEEHDNDYGRAVDWWGLGVVMYEMMCGRL
PFYNQDHEKLFELILMEEIRFPRTLSPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRF
FASIVWQDVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMEGVDSERRP
HFPQFSYSASGTA
NT seq
1482 nt
NT seq
+upstream
nt +downstream
nt
atgaacgacgtggccatcgtgaaggagggctggctgcacaagcgaggcgagtacatcaag
acgtggcggccgcgttacttcctcctgaagaacgacggcacattcatcggctacaaggag
cggccacaggacctggagcagcgtgagtcgcccctcaacaacttctccgtggcccaatgc
cagctgatgaagacggagcggccgcggcccaacaccttcatcatccgctgcctgcagtgg
accacggtcatcgagcgcacgttccacgtggagacgcccgaggagcgggaggagtggacc
accgccatccagacggtggccgacgggctcaagaggcaggaggaggagacgatggacttc
cggtcgggctcacccggcgagaactcgggggccgaggagatggaggtgtcgctggccaag
cccaagcaccgcgtgaccatgaatgagtttgagtacctgaagctgctgggcaaaggcacc
ttcgggaaggtgatcctggtgaaggagaaggccacaggccgctactacgccatgaagatc
ctaaagaaggaggtcatcgtggccaagaggattgtgaggagaaggccaggctttgtcacg
ccctccactggaagtgaggctgcctgtggcttgaagcgtgagagcagtgatcacgtctcc
acgtggtcactggacctgcagctgctggtcctcaggcgtggcctttgggacagcgggggt
cccccactccacagggcagacccctgcccagcccagggccaggttccagctctgcttccc
tcgcaggccctgaagtactccttccagacacacgaccgcctgtgcttcgtcatggagtac
gccaacgggggcgagcttttcttccacctgtcccgggagcgggtgtttcccgaggaccgg
gcccgcttctacggcgccgagatcgtgtcggccctggattacctgcactcggagaagaac
gtggtgtacagggacctcaaggtgggcgaggccggggaagaacatgacaacgactacggc
cgggcagtggactggtgggggctgggcgtggtcatgtacgagatgatgtgcggccgcctg
cccttctacaaccaggaccacgagaagctctttgagctcattctcatggaggagatccgc
ttcccccgcacactcagcccggaggccaagtctctgctctcggggctgctcaagaaggac
cccaagcagcggcttggtgggggctctgaggacgccaaggagatcatgcagcaccgattc
tttgccagcatcgtgtggcaggacgtgtacgagaagaagctcagcccgcccttcaagcct
caggtcacatctgagacggacaccaggtattttgatgaggagttcacggcccagatgatc
accattacgccacctgaccaagacgacagcatggagggggtggacagcgaacggaggccc
cacttcccccagttctcctactcggccagcggcacggcctga
DBGET
integrated database retrieval system