Bison bison bison (American bison): 104990507
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Entry
104990507 CDS
T08726
Symbol
TOP2A
Name
(RefSeq) DNA topoisomerase 2-alpha isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
bbis
Bison bison bison (American bison)
Pathway
bbis01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
bbis00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
104990507 (TOP2A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
bbis03032
]
104990507 (TOP2A)
03036 Chromosome and associated proteins [BR:
bbis03036
]
104990507 (TOP2A)
Enzymes [BR:
bbis01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
104990507 (TOP2A)
DNA replication proteins [BR:
bbis03032
]
Eukaryotic type
DNA Topoisomerases
104990507 (TOP2A)
Chromosome and associated proteins [BR:
bbis03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
104990507 (TOP2A)
Centrosome formation proteins
Centriole proteins
104990507 (TOP2A)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
104990507
NCBI-ProteinID:
XP_010840906
Ensembl:
ENSBBBG00000024833
UniProt:
A0A6P3HF98
LinkDB
All DBs
Position
Unknown
AA seq
1532 aa
AA seq
DB search
MEVSPLQPVNENMQVSKTKKNEDAKKRLSIERIYQKKTQLEHILLRPDTYIGSVESVTQQ
MWVYDEDIGINYREVTYVPGLYKIFDEILVNAADNKQRDPKMSCIRITIDPENNLISIWN
NGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDEEKKVTGGRNGYGAKLCNIFSTKFTVE
TASREYKKMFKQTWMDNMGKAGEMELKPFSGEDYTCITFHPDLSKFKMQSLDKDIVALMV
RRAYDIAGSTKDVKVYLNGNRLPVKGFRSYVDLYLKDKVDETGNPLKVIHEQVNHRWEVC
LTMSEKGFQQISFVNSIATSKGGRHVDYVADQIVTKLVDVVKKKNKGGVAVKAHQVKNHM
WIFVNALIENPTFDSQTKENMTLQVKSFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQ
IQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSTECTLILTEGDSAKTLAVSGLGVVGRDK
YGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMT
DQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKS
STPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQTDD
RKEWLTHFMEDRRQRKLLGLPDDYLYGQATTYLTYNDFINKELILFSNSDNERSIPSMVD
GLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNN
LNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPAKDDHTLKFLYDDNQRVEPEW
YIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLPMLPSYKNFKGTVE
ELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREY
HTDTTVKFVVKMTEEKLAEAERAGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILR
DFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQR
GYDSDPVKAWKEAQQKVPDEEENEESDSEKETEKSDSATDSGPTFNYLLDMPLWYLTKEK
KDELCKLRNEKEQELETLKRKSPSDLWKEDLAAFVEELEVVEAKEKQDEQIGLPGKGGKA
KGKKTQMVEILPSPSGKRVIPRVTEEMKAEAEKKIKKKIKSENTEGSPQEDGMEMESQKL
RLEKKQKREPVTKTKKQTTLPFKPIKKAKKRNPWSDSESDMSSNESNFDVPPREKESRRA
AAKTKFTMDLDSDEDFSDFDEDTQDDFVPSNASPPKIQTSPKHSNKELKPLKSASSVTEL
DADDAEDNAPPPPSSPAADFPAVTETINPVPKKNVTAKKTAAKSQSSTSTTGTKKRAAPR
KPKADPDLDSDVSKKPNAPKTKTRRKRKASSSDDSDSNFEKLISKAVTSKKPKEESDDFH
LDLDSAVGSRAKSVRTKKPIKYLEESDEDDFF
NT seq
4599 nt
NT seq
+upstream
nt +downstream
nt
atggaggtgtcgccactacagcctgtaaatgaaaatatgcaagtcagcaaaacaaagaaa
aatgaagatgctaagaaaagattgtctattgaaagaatctatcaaaagaaaacacaactg
gaacatatcctgctccgcccagacacctacattggctctgtggaatcagtgacccagcaa
atgtgggtttatgatgaagatattggcattaactatagggaagtcacttatgttcctggt
ttgtacaaaatctttgatgagattctagtcaatgctgcagacaacaaacaaagggaccca
aaaatgtcttgtattagaatcacaattgacccggaaaacaatttaattagtatatggaat
aatggaaaaggtattcctgttgtcgaacacaaagttgagaagatgtatgtcccagctctt
atctttggacagctcctaacttctagcaactatgatgatgaagaaaagaaagtaacaggt
ggtcgaaatggctatggagccaaactgtgtaacatattcagtaccaaatttactgtggaa
acagcaagtagagaatacaagaaaatgttcaaacagacatggatggataacatggggaaa
gctggtgagatggaactcaagccctttagtggagaagattatacatgtattaccttccac
cctgatttgtccaagtttaaaatgcaaagcctagacaaagatattgttgcactgatggtt
agaagagcatatgatattgctggatccactaaagatgtcaaggtctatctcaatggaaat
aggcttccagtgaaaggattccgtagctatgtagatctgtatctgaaggataaggtagat
gaaactggcaatccattgaaagttatccatgaacaagtaaaccacaggtgggaagtatgt
ttaacaatgagtgaaaaaggctttcagcaaattagctttgtcaacagcattgctacttcc
aagggtggccgacatgttgattatgtagctgatcagattgtgactaaacttgttgatgtt
gtgaagaaaaagaacaagggtggtgttgcagtaaaagcacatcaggtaaaaaatcacatg
tggatttttgtgaatgccttaattgaaaacccaaccttcgactcccagacaaaagagaac
atgactttacaagtcaagagctttggatcaacatgccagctgagtgaaaaattcatcaaa
gctgcgattggctgtggtattgtagaaagtatactaaattgggtgaaatttaaggcccaa
atccagttaaacaagaagtgttctgctgtaaaacataacagaatcaaaggaattcccaaa
cttgatgatgccaatgatgcaggaggccgaaactctactgagtgtacgcttatcctgaca
gagggagactcagctaaaactttggctgtttcaggccttggtgtggttgggagagacaag
tatggggttttccctcttagaggaaaaatactcaatgttcgagaagcttctcataaacag
ataatggagaatgctgaaattaacaatataattaagattgtgggtcttcagtacaagaaa
aactatgaagatgaagattcactgaagactctacgttatggaaagataatgattatgaca
gatcaggaccaagacggttcccatatcaaaggcttgctgattaattttatccatcacaac
tggccctctcttctgcgacatcgttttctggaggaatttatcactcccattgtaaaggtg
tctaaaaacaaacaagaaatggcattctatagccttcctgagtttgaagaatggaagagt
tctacaccaaatcataaaaaatggaaagtcaaatattacaaaggtttgggtaccagcaca
tcaaaggaagctaaagaatactttgcagatatgaaaagacatcgtatccaatttaaatat
tccggtcccgaagatgatgctgcaatcagcctggcctttagcaaaaagcagacagatgat
cgaaaggaatggttaactcatttcatggaagatagaagacaacgaaagttacttggcctt
cctgatgattatttgtatgggcaagctaccacatatctgacatacaatgacttcataaac
aaggaacttatcctgttttcaaattctgataatgaaaggtctatcccatctatggtggat
ggtttgaaaccaggtcagagaaaggttttgtttacatgtttcaaacggaatgacaagcga
gaggtgaaggttgcccagttagctgggtcagtagctgagatgtcctcttatcatcatggt
gagatgtcactaatgatgaccattatcaatttggctcagaactttgtgggcagcaataat
ctgaaccttttgcagcccattggtcagtttggtaccaggttgcatggtggcaaggactct
gctagtcctcgatacatcttcacaatgctcagccctttggctcggttgttatttccagca
aaagatgaccatacattaaagtttttatatgatgacaaccagcgtgttgagcctgaatgg
tatattcctattatacccatggtgttgataaatggcgctgaaggaattggtactgggtgg
tcctgcaaaatccccaactttgatgttcgtgaagttgtgaataacatcagacgtttgatg
gatggagaagaacctttgccaatgcttccaagttacaagaacttcaagggtactgttgag
gagctggctccaaatcaatatgtgattagtggtgaagtggctattcttaattctacaacc
attgaaatctcagagcttcccatcagaacgtggacccagacgtataaggaacaggttctt
gagcccatgttgaatggcactgagaagacaccgcctctcataacagattatagggaatac
cacacagacaccactgtgaagtttgttgtgaagatgactgaagaaaagctggcggaggca
gagagagctggactacacaaagtcttcaaactccaaactagtctcacatgcaactctatg
gtcctctttgaccatgtaggctgtttaaagaaatacgacacagttttggatattctaaga
gacttctttgaactcaggcttaaatattatggattaagaaaagaatggcttctaggaatg
cttggtgctgaatctgctaaactgaataatcaggctcgctttatcttagagaaaatagat
ggcaaaataatcattgaaaataagcctaagaaagagttaattaaagttctgattcagaga
ggatatgattcggatcctgtgaaggcttggaaagaagcccagcaaaaggttccagatgaa
gaagaaaatgaagaaagtgacagtgaaaaggaaactgaaaagagtgactctgcgacagat
tctggacctaccttcaactaccttcttgacatgcctctttggtatctaaccaaggaaaag
aaagatgaactgtgcaaactaagaaatgaaaaagagcaagagctagaaacattgaagaga
aagagtccatcagatttgtggaaagaagacttggctgcttttgttgaagagctggaggtt
gttgaagcaaaggagaaacaagatgaacaaataggacttcctgggaaaggtgggaaagca
aaggggaaaaaaacacaaatggtagaaattttgccttctccaagtggaaaaagagtcatc
ccccgagtgactgaagaaatgaaagcagaggcagaaaagaaaattaaaaagaaaattaag
agtgaaaatactgaaggaagccctcaagaggatggaatggaaatggaaagccaaaaactg
agactggaaaagaaacagaaaagagagccagttaccaagacaaagaaacaaactacattg
ccatttaaaccaatcaagaaagcaaagaaaagaaacccctggtccgattcagaatcagat
atgagcagtaacgaaagtaattttgatgtccctccacgagaaaaagagtcacggagagca
gcagcaaaaaccaaattcacaatggatttggattcagatgaagatttttcagattttgat
gaagacactcaagatgattttgtcccatcaaatgctagtccacctaagatccaaacttcc
ccgaaacatagtaacaaagaactgaagccactgaagagtgcctcatcagtaacagagctt
gatgctgatgatgctgaggataatgcaccacctcctccaagctctcctgctgcagatttc
ccagctgtaactgaaaccataaaccctgttcctaaaaagaatgtgacagcaaagaagaca
gcagcaaaaagccagtcttccacctccactacaggcaccaaaaaaagggctgcaccgaga
aaacccaaagcggatccagacttggactccgatgtctctaaaaagcctaatgcccccaaa
accaagactcgccgcaaaaggaaggcgtcctcctctgatgattccgactctaattttgag
aaactgatctccaaagcagtcacaagcaagaaacccaaggaggaaagtgatgatttccat
ctggacttggactcagctgtgggttctcgggcaaaatctgtaagaacaaagaaacctata
aagtaccttgaagaatcagatgaagatgatttcttttaa
DBGET
integrated database retrieval system
