| Entry |
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| Name |
(RefSeq) multidrug resistance-associated protein 4
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| KO |
| K05673 | ATP-binding cassette, subfamily C (CFTR/MRP), member 4 |
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| Organism |
bbis Bison bison bison (American bison)
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| Pathway |
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| Brite |
KEGG Orthology (KO) [BR:bbis00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
104992857
09132 Signal transduction
04024 cAMP signaling pathway
104992857
09150 Organismal Systems
09154 Digestive system
04976 Bile secretion
104992857
04981 Folate transport and metabolism
104992857
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
104992857
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:bbis02000]
104992857
Transporters [BR:bbis02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
104992857
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
1282 aa
MYSVLPEDRSQHLGEELQGYWDQEVLRAEKDAREPSLTKAIIKCYWKSYVVLGIFTLIEE
STRVVQPIILGKIIGYFENYDPSDSAALYEAHGYAGVLSACTLVLAILHHLYFYHVQCAG
MRLRVAMCHMIYRKALRLSNSAMGKTTTGQIVNLLSNDVNKFDQVTIFLHFLWAGPLQAI
VVTALLWMEIGISCLAGMAVLIILLPLQSCIGKLFSSLRSKTAAFTDTRIRTMNEVITGI
RIIKMYAWEKSFADLITNLRRKEISKILRSSYLRGMNLASFFVASKIIVFVTFTTYVFLG
NVITASRVFVAVSLYGAVRLTVTLFFPSAVEKVSEAFVSIRRIKNFLLLDEITQLHSQLP
SDGKMIVNVQDFTAFWDKASDTPTLQSLSFTVRPGELLAVVGPVGAGKSSLLSAVLGELP
PNQGQVSVHGRIAYVSQQPWVFSGTVRSNILFGKKYEKERYEKVIKACALKKDLQLLEDG
DLTMIGDRGTTLSGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVSRHLFELCICQALH
EKIRILVTHQLQYLKAASQILILKDGQMVQKGTYTEFLKSGIDFGSLLKKENEEAEPSPV
PGSPTLRNRTFSESSVWSQQSSRPSLKEATPEGQDTENIQVTLTEESRSEGKVGFKAYKN
YFTAGAHWFIIIFLILVNLAAQVSYILQDWWLSYWANQQSALNVTVNGQGNVTEKLDLNW
YLGIYSGLTASTVLFGIVRSLLVFFVLVSSSQTLHNQMFESILRAPVLFFDRNPIGRILN
RFSKDIGHMDDLLPLTYLDFIQTFLQVIGVVGVAVAVIPWIAIPLVPLGIVFFVLRRYFL
ETSRDVKRLESTTRSPVFSHLSSSLQGLWTIRAYKAEQRFQELFDSHQDLHSEAWFLFLT
TSRWFAVRLDAICAVFVIVVAFGSLILAKTLDAGQVGLALSYALTLMGMFQWCVRQSAEV
ENMMISVERVIEYTDLEKEAPWEYQKRPLPSWPHEGVIIFDNVNFSYSLDGPLVLKHLTA
LIKSKEKVGIVGRTGAGKSSLIAALFRLSEPEGKIWIDKILTTEIGLHDLRKKMSIIPQE
PVLFTGTMRKNLDPFNEHSDEELWNALEEVQLKEAIEDLPGKMDTELAESGSNFSVGQRQ
LVCLARAILRKNRILIIDEATANVDPRTDELIQKKIREKFAHCTVLTIAHRLNTIIDSDK
IMVLDSGRLKEYDEPYVLLQNRDSLFYKMVQQLGKAEAAALTETAKQVYFKRNYPDITHN
GHVVMNASSGQPSALTIFETAL |
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| NT seq |
3849 nt +upstreamnt +downstreamnt
atgtactcagtgcttccagaagatcgctcccagcaccttggagaagagctgcaagggtac
tgggatcaagaggttttgagagccgagaaagatgcacgggagccttctttaacaaaagca
atcataaaatgttactggaaatcctatgtagttttgggaatttttacattaattgaggaa
agtaccagagtagttcagcccataattctggggaaaattattggttattttgaaaactac
gatccctctgattctgctgctttgtacgaagcccacggctatgccggggtgctgagcgcc
tgcacgcttgtcttggccatcctacaccacttgtatttctaccacgtccagtgtgcgggg
atgaggctgagagtagccatgtgccacatgatttaccgcaaggccctccgcttgagtaac
tcggccatggggaagaccaccacaggccagatagtcaacctgctatccaacgatgtgaac
aagtttgatcaggtaacgatattcttgcactttctgtgggcagggccactgcaggctatc
gtagtgaccgccctgctctggatggaaataggaatatcgtgtcttgctgggatggcggtt
ctcattattcttctgcctttgcaaagctgcatcgggaagttgttttcgtcactccggagt
aagactgcagccttcacagacaccaggatcaggacaatgaatgaagttataacgggcatc
agaataataaaaatgtatgcttgggaaaagtcttttgcagaccttatcaccaatttgaga
agaaaggaaatttccaagattctgagaagttcctaccttagaggaatgaatttggcatca
ttttttgttgcgagcaaaatcatcgttttcgtcaccttcaccacctatgtgttccttggc
aacgtgatcacagccagccgtgtgtttgtggcggtgtcgctgtacggggctgtgcggttg
acagtcaccctcttcttcccttcggccgtcgagaaggtgtcagaggcattcgtcagcatc
cgaagaatcaagaacttcctgttacttgatgagataacacagctccactctcaactgcca
tcagatggtaaaatgatcgtgaatgtgcaggatttcactgctttttgggataaggcatca
gacaccccaaccctacaaagcctttcctttactgtcagacccggtgaactgttagctgtg
gttggacctgtgggagcaggaaagtcatcactgttaagcgctgtgctgggggagctgccc
ccgaaccagggacaggtcagcgtgcacgggaggatcgcgtatgtttctcagcagccctgg
gtgttctcaggaactgtgaggagtaacattttatttgggaagaaatatgaaaaggaacga
tatgaaaaagtgataaaggcttgtgctttgaaaaaggatttacagcttctggaggatgga
gacctaactatgataggagaccggggaaccacactgagtggagggcagaaagcccgggtc
aaccttgccagagccgtgtatcaggatgcagacatctacctcctagacgatccgctcagc
gcagtggacgcagaagttagcaggcacttgtttgaactgtgtatttgtcaagccttgcac
gagaagatcagaatcttagtgactcatcagttgcagtacctaaaagctgcaagtcagatt
ctgatattaaaagatggccaaatggtgcaaaaggggacttacactgagttcctgaaatcc
gggatagattttggttcccttttaaagaaggagaatgaggaggctgaaccatctccggtt
ccaggaagtcctaccctgaggaaccgcaccttttccgagtcttcggtttggtctcaacag
tcttccagaccctccttgaaagaggccactccagagggccaagacaccgaaaatatacag
gttaccctaactgaggagtcccgttcggaaggaaaagttggttttaaggcttataagaat
tacttcacagccggtgctcactggtttatcatcattttcctcattctagtaaaccttgca
gctcaggtttcctacatcctgcaggattggtggctttcatactgggccaatcaacagagt
gccctaaatgtcactgttaatggacaaggaaatgtaaccgagaagctcgatctgaactgg
tacttaggaatttactcagggttaactgcatccactgtcctgtttggcatcgtcagatct
ctcctggtattcttcgtccttgttagttcttcacaaactttgcacaatcaaatgttcgag
tccattttgagagctccggtattgttcttcgatagaaatccaataggaagaattttaaat
cgtttctccaaagacattggacatatggatgacttgctgccgctgacgtatcttgatttc
atccagacatttctacaagtgattggtgtggtgggcgtggcagtggcagtgattccttgg
attgccatacccctggttccccttggcattgttttctttgttctccggcgatatttctta
gaaacatcgcgagatgtcaaacgcctagaatctacaactcggagcccggtgttttcccac
ttatcatcttctctccagggactctggaccatccgggcgtacaaagccgaacagaggttt
caggaactgttcgactcacaccaggacttgcactcagaggcttggttcttgtttctgacg
acgtcccgatggttcgctgtgcgtctggatgccatctgtgctgtgtttgtcattgttgtt
gcctttgggtccctgattctggcaaaaactttggacgctggtcaggttggcctggcgcta
tcctacgccctcacgctcatggggatgttccagtggtgtgtcaggcaaagtgctgaagtt
gaaaatatgatgatttcagtggaaagggtgatcgagtatacagatctggaaaaggaagcg
ccctgggaataccaaaaacgcccactgccgtcctggccccatgaaggcgtgatcatcttt
gacaacgtgaacttctcatatagcctagatgggcctctggtattgaagcacctgacagca
ctcattaaatcaaaagaaaaggttggcattgtgggaagaacaggagctggaaaaagttcc
ctcatcgctgccctttttagattgtcggagcctgaaggtaaaatctggattgataagatc
ttgacaactgaaattggtcttcatgatttaaggaagaaaatgtcaattatacctcaggaa
cctgttttattcactggaacaatgaggaagaatctggaccccttcaatgagcattcagat
gaggaactgtggaatgccttagaagaggtgcaactgaaggaagccatcgaagatcttcct
ggtaaaatggatactgaattagcagaatccgggtcaaactttagtgttggacagagacaa
ctggtgtgccttgccagggctatcctcaggaaaaatcggatattgattattgacgaagcc
acggccaatgtggatccaagaactgatgagttaatacaaaaaaaaatccgtgagaaattt
gcccactgcactgtgctaaccatagcacacagattgaatactattattgatagcgacaag
ataatggttttggattcagggagactgaaagaatatgatgagccatatgttttgctgcaa
aatagagacagcctattttataagatggtgcaacaactgggcaaggccgaggccgctgcc
ctcactgaaacagcaaaacaggtgtacttcaagaggaattatccagatattactcacaat
ggccatgtggttatgaacgcttccagtggacagccctcagccttaacgatttttgagaca
gcactgtga |
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