Bison bison bison (American bison): 104993272
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Entry
104993272 CDS
T08726
Symbol
TOP2B
Name
(RefSeq) DNA topoisomerase 2-beta
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
bbis
Bison bison bison (American bison)
Pathway
bbis01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
bbis00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
104993272 (TOP2B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
bbis03032
]
104993272 (TOP2B)
03036 Chromosome and associated proteins [BR:
bbis03036
]
104993272 (TOP2B)
Enzymes [BR:
bbis01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
104993272 (TOP2B)
DNA replication proteins [BR:
bbis03032
]
Eukaryotic type
DNA Topoisomerases
104993272 (TOP2B)
Chromosome and associated proteins [BR:
bbis03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
104993272 (TOP2B)
Centrosome formation proteins
Centriole proteins
104993272 (TOP2B)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
DUF7180
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
104993272
NCBI-ProteinID:
XP_010844754
Ensembl:
ENSBBBG00000011838
UniProt:
A0A6P3HZI5
LinkDB
All DBs
Position
Unknown
AA seq
1607 aa
AA seq
DB search
MCPYILVYPLTLFDQNNAAKKEESEIANKNDSSKKLSVERVYQKKTQLEHILLRPDTYIG
SVEPLTQLMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTCIKVSIDPE
SNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNI
FSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQPDLSKFKMEKLD
RDIVALMTRRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLDETGVALKVIHEL
ANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKKKNKAGVSVK
PFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAASNCGIVESIL
NWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGDSAKSLAVSG
LGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYDDAESLKTLR
YGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKNKQELSFYSI
PEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPEDDAAITLA
FSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELILFSNSDNE
RSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQALMMTIVNLA
QNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSTLARLLFPAVDDNLLKFLYDD
NQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLDGLDPHPMLPNY
KNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPMLNGTDKTPA
LISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLFDHMGCLKKY
ETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKITIENRSKKD
LIQMLVQRGYESDPVKAWKEAQEKAAEEEESQNQHDDSSSDSGTPSGPDFNYILNMSLWS
LTKEKVEELIKQRDAKGREVSDLKRKSPSDLWKEDLAAFVEELDKVEAQEREDVLAGMAG
KAIKGKVGKPKVKKLQLEETMPSPYGRRVVPEITAMKADASKKLLKKRKGDPDATAVRVD
FDEELSGAAVEGGEEAPIPSAPVHRGPKPKREKKEPGTRVRKTPTSSGKPSAKKVKKRNP
WSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEEDDADDDDDNNDLEEL
KVKASPIANDGEEEFVPSDGLDKDEYTFSPGKSKAAPEKSSHDKKSQDFGTLFSFPSYSQ
KSEDDSAKFDSNEEDSASVFSPSFGLKQTEKVPSKTVAAKKGKPSLDTASKPKRAPKQKK
VETVNSDSDSEFGVPKKTAPKGKGRGAKKRKASGSENEGDYNPGRKTSKPPSKKPKKTSF
DEDSDVDLFPSDLTTEPPSLPRTGRARKEVKYFADSDEEDVDFAMFN
NT seq
4824 nt
NT seq
+upstream
nt +downstream
nt
atgtgtccgtacattttagtttaccctttgactctctttgatcagaacaatgctgcaaaa
aaggaagagtcagaaattgcaaacaaaaatgattcttcaaagaagttgtccgtcgagaga
gtgtatcagaaaaagacacaactcgaacatattctgcttcgtcctgatacttacatcggg
tcagtggagccattgacacagctcatgtgggtatatgatgaagatgtaggaatgaattgc
agagaggttacctttgtgccgggtttatataagatctttgatgaaattttggttaatgca
gctgataataaacagagggataagaacatgacctgtattaaagtttctattgatcctgaa
tctaacataataagcatttggaataatgggaaaggcattccagtagtagaacacaaagta
gagaaagtttatgttcctgcattaatttttggacagcttttaacgtccagtaactatgac
gatgatgagaaaaaagtaacaggtggtcgcaatggttatggtgcaaaactttgtaatatt
ttcagtacaaagtttacagtggaaaccgcttgcaaagagtacaagcatagttttaaacag
acatggatgaataatatgatgaagacttctgaagccaaaattaaacattttgatggtgaa
gattacacatgtataacattccaaccagatctgtccaaatttaagatggagaagcttgac
agggatattgttgctctcatgaccagaagagcttatgatttggctggttcctgcaaggga
gtcaaggtcatgtttaatggaaagaaattgcccgtaaatggatttcgcagttatgtagat
ctttatgtgaaagacaaattggatgaaacgggagtggctctaaaagttattcatgaactt
gcaaatgaaagatgggacgtttgtctcactttgagtgaaaaaggattccagcaaatcagc
tttgtaaatagcattgcaacaacaaaaggtggacggcatgtggattacgtagtagaccaa
gttgttggtaaactgattgaagtagttaagaaaaagaacaaagctggtgtgtcagtgaaa
ccatttcaagtaaaaaatcatatatgggtttttattaactgccttattgaaaatccaact
tttgattctcaaactaaggaaaacatgactttgcagcccaaaagttttggatccaaatgc
caactatcagaaaaattttttaaagcagcctctaactgtggcattgtagaaagtatcctg
aactgggtgaaatttaaggctcagacacagctgaacaagaagtgttcatcagtaaagtac
agtaaaatcaaaggtattcccaaattggatgatgctaatgatgctggtggcaaacattcc
ctggagtgcacactgatcctgacagaaggagactctgccaagtccctggccgtgtctgga
ttaggcgtcattgggagggacagatatggggtctttcccctcaggggaaagattcttaac
gtgcgggaagcttctcacaaacagatcatggaaaatgcagaaataaacaatattattaaa
atagttggtctacaatataagaaaagttatgatgatgcagaatctctgaaaactttacgc
tatggaaagattatgattatgactgatcaggatcaagatggttctcacataaaaggcctg
cttattaatttcatccatcacaattggccatcacttttgaagcatggttttcttgaagag
ttcattacccctattgtaaaggctagcaaaaataagcaggaactttccttctacagtatt
cctgaatttgatgagtggaaaaaacatatagaaaaccagaaagcctggaaaataaaatac
tacaaagggttgggtaccagtacagctaaggaagccaaggaatattttgctgatatggaa
aggcaccgtatcttatttagatatgctggtcctgaagatgatgctgccattaccttggca
ttcagtaagaagaagatcgatgacagaaaagaatggttaacgaactttatggaagatcgg
agacagcgtaggttacatggcttaccagagcaattcttatatggtacagcaaccaagcat
ttgacttataatgattttatcaacaaggaattgattctcttctcaaactcagacaatgaa
agatctataccatctcttgttgatggttttaaaccaggtcaacgaaaagttttatttacc
tgtttcaagaggaatgataaacgtgaagtgaaagttgcacagttggctggatctgttgct
gagatgtctgcttatcatcatggagaacaagcattgatgatgactattgtgaacttggct
cagaactttgtggggagcaacaacatcaacttgcttcagcctattggtcagtttggaact
cgacttcatgggggcaaagatgctgcgagccctcgttatattttcacaatgttgagcact
ttagcaagactgctttttcctgctgtggatgacaacctgcttaaattcctttatgatgat
aatcagcgtgtggagcctgagtggtatattcccataattccaatggttttaataaatggt
gctgagggcattggcacagggtgggcttgtaagctgcccaactacgatgccagagagatt
gtgaacaatgtcaggcgaatgctcgatggcctggatcctcatcccatgcttccaaactac
aaaaactttaaaggaacgatccaagaacttggtcaaaaccagtatgcagtcagtggtgag
atatttgtggtggatagaaacacggtggagattaccgagctccccgtcagaacttggaca
caggtatacaaagaacaggttttagaacctatgctaaatggaacagataaaacaccagca
ttaatttctgattataaagaatatcatactgatacaactgtgaaatttgtggtgaaaatg
actgaagagaagctagcacaagcagaagctgctggattgcacaaagtttttaaacttcaa
actactcttacttgtaattccatggtactctttgatcatatgggatgtctgaagaagtat
gaaactgtgcaagatattttgaaagaattctttgatttacgattaagctattatggttta
cgaaaggagtggcttgtaggaatgttgggagcagaatctactaagcttaataatcaagcc
cgtttcattttagagaagatacaagggaaaatcactatagagaataggtcaaagaaagat
ttgattcaaatgttagtccagagaggttatgaatctgacccagtgaaagcctggaaagaa
gcacaagaaaaggcagcagaagaggaagaatcacaaaaccagcatgatgatagttcctct
gattcaggaactccttcaggccctgattttaattatattttaaatatgtctctatggtct
cttactaaagaaaaagttgaagaactgattaaacagagagatgcaaaagggcgagaggtc
agtgatcttaaaaggaaatctccttcagatctttggaaagaagatttagcagcttttgtt
gaagaactggataaagtggaagcgcaggaacgagaagacgttctggctgggatggccgga
aaagcaatcaaggggaaggttggcaaacctaaggtgaagaagcttcagctagaggagacg
atgccctccccttacggcaggagagtggttcctgagatcactgccatgaaggcagatgcc
agcaagaagctgctgaagaagagaaagggcgatccggatgccacagcagtccgagtggac
tttgatgaagagctcagcggagcagcagtggaaggcggggaagaggcgccgatcccatca
gctcctgtacacagaggccccaaacccaaaagggagaaaaaagagcctggtaccagggtg
agaaaaacacctacatcatctggtaaaccgagtgcaaagaaagtgaagaaacggaatcct
tggtcagatgatgaatccaagtcagaaagtgacttggaagaaacagaacctgtggttatt
ccaagagactctttacttaggagagcggctgctgaacggccgaagtatacattcgatttc
tcggaagaggaggaagatgacgccgatgatgatgacgacaataatgacttagaggagctg
aaggtcaaagcatctcccatagcaaatgatggagaagaggagtttgtcccctcagatggc
ctagataaagatgaatacacattctcaccaggcaaatcgaaagctgctccagaaaagtct
tcccacgacaagaagagtcaggattttgggactctcttctcttttccttcatactctcag
aagtcagaagatgattcagctaaatttgacagtaatgaagaagattctgcttctgtattt
tcaccatcatttggtctgaagcaaacagaaaaagttccaagtaaaacagtagctgctaaa
aagggaaaaccatctttagatacagcctctaagcccaagagggcccccaaacagaagaaa
gtagagactgtgaactctgactcggattctgaattcggcgttccaaagaaaacagcacca
aaaggtaaaggccgaggggcaaagaaaaggaaagcatctggctctgaaaacgaaggtgat
tacaatcctggcaggaaaacctccaaaccaccaagcaagaagccgaagaaaacctctttt
gatgaggactcagatgtggacctcttcccctcagacctcaccaccgagccaccgtcgctg
ccgcggactggccgggcaaggaaagaagtaaaatattttgcagactctgacgaggaagat
gtcgattttgcgatgtttaattaa
DBGET
integrated database retrieval system
