KEGG   Bison bison bison (American bison): 104993460
Entry
104993460         CDS       T08726                                 
Symbol
EIF2S1
Name
(RefSeq) eukaryotic translation initiation factor 2 subunit 1
  KO
K03237  translation initiation factor 2 subunit 1
Organism
bbis  Bison bison bison (American bison)
Pathway
bbis04137  Mitophagy - animal
bbis04140  Autophagy - animal
bbis04141  Protein processing in endoplasmic reticulum
bbis04210  Apoptosis
bbis04932  Non-alcoholic fatty liver disease
bbis05010  Alzheimer disease
bbis05012  Parkinson disease
bbis05014  Amyotrophic lateral sclerosis
bbis05020  Prion disease
bbis05022  Pathways of neurodegeneration - multiple diseases
bbis05160  Hepatitis C
bbis05162  Measles
bbis05164  Influenza A
bbis05168  Herpes simplex virus 1 infection
bbis05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:bbis00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    104993460 (EIF2S1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    104993460 (EIF2S1)
   04137 Mitophagy - animal
    104993460 (EIF2S1)
  09143 Cell growth and death
   04210 Apoptosis
    104993460 (EIF2S1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    104993460 (EIF2S1)
   05164 Influenza A
    104993460 (EIF2S1)
   05162 Measles
    104993460 (EIF2S1)
   05168 Herpes simplex virus 1 infection
    104993460 (EIF2S1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    104993460 (EIF2S1)
   05012 Parkinson disease
    104993460 (EIF2S1)
   05014 Amyotrophic lateral sclerosis
    104993460 (EIF2S1)
   05020 Prion disease
    104993460 (EIF2S1)
   05022 Pathways of neurodegeneration - multiple diseases
    104993460 (EIF2S1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    104993460 (EIF2S1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    104993460 (EIF2S1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03012 Translation factors [BR:bbis03012]
    104993460 (EIF2S1)
   04131 Membrane trafficking [BR:bbis04131]
    104993460 (EIF2S1)
Translation factors [BR:bbis03012]
 Eukaryotic type
  Initiation factors
   eIF-2
    104993460 (EIF2S1)
Membrane trafficking [BR:bbis04131]
 Autophagy
  ER-phagy
   ER stress-related proteins
    104993460 (EIF2S1)
SSDB
Motif
Pfam: EIF_2_alpha S1
Other DBs
NCBI-GeneID: 104993460
NCBI-ProteinID: XP_010845034
Ensembl: ENSBBBG00000007485
UniProt: A0A6P3I2C6
LinkDB
Position
Unknown
AA seq 315 aa
MPGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSIN
KLIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLE
YTKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLDLNEDEREVLINNI
NRRLTPQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTETMPIKINLIAPPRYVMTTT
TLERTEGLSVLNQAMAVIKEKIEEKRGVFNVQMEPKVVTDTDETELARQLERLERENAEV
DGDDDAEEMEAKAED
NT seq 948 nt   +upstreamnt  +downstreamnt
atgccgggtctaagttgtagattttatcaacacaaatttcctgaggtggaagatgtagtg
atggtgaatgtaaggtccattgctgaaatgggcgcttatgtcagcttgctggaatacaac
aacatcgaaggcatgattcttctgagtgagttgtcaagaaggcgtatccgttctataaac
aaactcatccgaattggcaggaatgaatgtgtggttgttattagagtggacaaagaaaaa
ggatatattgatttgtcaaaaagaagagtttcaccagaggaagcaatcaaatgtgaagat
aaatttaccaaatccaaaactgtttacagcattcttcgtcatgttgctgaggtcttagaa
tataccaaggatgagcagctggaaagcctattccagaggactgcctgggtcttcgatgac
aagtacaagagacccggatatggtgcctatgatgcatttaagcacgcagtctcagaccca
tctattttggatagcttagatttgaatgaagatgaacgtgaagtactcattaacaatatt
aataggcgtttgaccccccaggctgtcaaaattcgagcagatattgaagtggcttgttat
ggttatgaaggcatcgatgccgtaaaagaagctctgagagcgggtttgaattgttctaca
gaaaccatgcccatcaaaattaatctaatagctcctcctcggtatgtaatgactacaacc
accctggagagaacagaaggcctctctgtcctcaatcaagctatggctgttataaaagaa
aaaattgaggaaaagaggggtgtcttcaatgttcaaatggagcccaaagtggtcacagat
acagatgagaccgaacttgcaaggcagctggagaggcttgagagagaaaatgcagaagtg
gatggagatgatgatgcagaagaaatggaagccaaagctgaagattaa

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