Bison bison bison (American bison): 104993491 Help Entry 104993491         CDS       T08726                                  Symbol SYNE2 Name (RefSeq) LOW QUALITY PROTEIN: nesprin-2   KO K19346   nesprin-2 Organism bbis  Bison bison bison (American bison) Pathway bbis04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:bbis00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     104993491 (SYNE2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:bbis03036]     104993491 (SYNE2) Chromosome and associated proteins [BR:bbis03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     104993491 (SYNE2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  CH Spectrin_SYNE1 KASH Spectrin SYNE1 CAMSAP_CH TetR_C_29 Motif Other DBs NCBI-GeneID:  104993491 NCBI-ProteinID:  XP_010845102 Ensembl:  ENSBBBG00000005964 UniProt:  A0A6P3I0F2 LinkDB All DBs Position Unknown AA seq 6971 aa AA seqDB search MMLCSRLLPILIGLFTLLLLMWGSSLYIMDVNFLSVHFFNCDEHDIISLSQRMASSPVLP AEDQQVSLGIDDLHFSLQAEQEDTQKKTFTCWINSQLAKHTPPSVVTDLFTDIKKGHVLL DLLEVLSGQQLPRDKGSNTFQCRINIENALTFLQNQSIKLINIHVTDIIDGNPSIVLGLI WTIILHFHIEELARTLPGSYSQPSLDSVSAVDSSPTSSPPAKKCSKVQERWRMSAKKALL QWAQEQCASYESVNVTDFKSSWRNGRAFLAVIHALRPDLIDMKSVKHRSNRDNLKEAFRI AEQELKIPKMLEPEDVDVVNPDEKSIMTYVAQFLQYSKKAPGSGDEAQGKVKDAMVWLAL QEKKVQKMLRDSENETYCKTYESLLSFLESFNKEKERFLDVLTIKRNVDDLNKDQLQLGE AWDGLNYQINVWQTELNRVLPSPLYQIETWLQEVEKLIDEDLSVSQDYSEAMALTQEKIT LFQSLMDKFDCHLNTLLAFENRDENHLPLVPPEKLEEMKRRINNISGKKVIPRLEFHYYE CSVLGLLEEVKSKLLVWNIKYGSKESVELLLEDWHKFIEEKEFLAQLETSFQKCEEIHNN LAGEYPNISKQYTMVKYHFSMYRENILNVKSTLQKVLACWATYVENLRLLKACFEETKKE QMKEVPFETLSQWNLQHTTLNEVGNFLFQVSNDEVGLSISKELKRLNKRWRKLITKAQPE VNLPLMKLQDEPFLDNSGNIQLSKEENLAVGFSTDRSSQLPENHNQNIMAGEVHEKENED FSGPLKVAKEVEKLIGQVETWEAETTSVLDLLRQQDDVETSVEESLQHLIAKGSMYEELV SRIEDTLQMDVQHVSSQESLQHVLTAGLQAKIQEAKEKVQISMIKLVAVLKNSTDVSQDL DVRLKVEETQKELESYITRAEQLLGQKESQRGLITKYKEALIISNTKSLAKYLKAVEELK NNVTDDVKLSLEEKSRDICAKWESLHHEMSLYIQQLKIDIEKGKLSDSIAKLEKQINKEK KLIRRGRTKGLIKEHEACFSEEGSLYQLDHHMDVLRELCEELTSQKSQQEVRRALKDYEQ KIERLRKCASEIHMTLQPTLGGTSKNKGTTDASKNGGGNTLSEVPSAKSDNQPSAEKAME LVQNFNLESKLKLQQEESIMEKYEKGHSTSIDSLLERYDTHKGTLELYLQNSIARITSDF SSDKERSSVCLQDKLTDLQVLKNETDACWKEFEITSLKLEELESDIKKPFIVKARDKLKE KERELQMTLKSRMESLETVLKMVLPMEKESLLLCDTDLLLREMAIQEFHLTDADDIYQNL RNIQDSVVKQIETCKNLGQSGNFALKELHPLDLHAAQNIILKHRTQLEEMNHRVQKSKDA LEALEDFLASLRAAELSSELLTDHSASDSQGVPANTLTVENKEREIHRMRDKARHLDEHL KMLGISIKDSEQGENTSCEKLLDALSKNLSETRSGGQEEVTEEDKLLGACVSKNDELLKN IQDVHNQISKIGLKDPTVPAIKQRRKSLIRLDKDLDEYEEEKKHLQEMVNSLPQFKDGRD KALSQRCQDTAVLWENVKTLVTECLDQCERVLELLKQYQNFKSVLTALIQKEENVLSVQA SYMGKENLKKRIAEIEVVKEEFNEHLEVVDKIHQICKNLQFHLNKMRTFEEPPFEKEANI IVDRWLDINEKTEDYYDNLGRALALWDKLFDLKNGIDEWTEKVLQKLELHQLTEEEREKL KEELQVHEQKPSEFSKRVAKIQFLLQSSEIPLELQVMESSILNKIERVKMCLTGGSHCGA ISGSTAELREDLDQAKTQIGMTESLLNALSPSDSLEIFTKLEEIQQQILQQKHSMILLEN QIGCLTPELSELKKQYESVSDLFNTKKSVLQDHFSKLLNDQCKNFNDWFGSIKMNLKECF EPSETKKCVEQKLQKLSDFLTLEGRGSEIQQVGTVLNHVKKHLPKAPVKKLNSWIVSQEV ELEKMESICQARAKELEECLQQLLRLHNDHRNLSKWLTNQEEIWKEMEGTREKTELFCQA LARKREQFESMAQLNNSVKQYGITEEEEIVTESTHLIDRYQTLLRQICETDKEDKLPPAE DQSFNDLAHDVIHWITGIKESLMVLNSSEGKMPLEERIHKIKEIILLKPEGDAKIQAIMS QAESSKTPVVPKTLTDIKNQWDNTLHLANTYLSHQEKLLLEGEKYLQSKEDLRLMLTELK KKQEVGFALQPGLQEKKAQLKIYKKFLQKAQDLTFLLEELKSQGNYLLECTKNPNFSEEP WLEIKHLHESLLQQLQDSVQKLEGHVQEHDSYQLCVTDLNTALDYIAKEFVCFSDRPVDE RAVEEKLQKLQDLENSLHLQDGPLEKILTLAKSVKQNTSSAGQKIIKDDIKSLKCKQKDL ENRLESAKQEMENCLNSILKSKCSTENKAKFPLPGREEQVTSDVQESTQDSAAMEKLEED WEINKNSALEMILSRQLSLDVQESMKNTEDEQKVNELQNQPLELDVMLRNEQLKEIEELC TQMQGKKAAIEPLEQSECLNKTESSALVLHDESYSVQHLDNLLQALITLKKKKESQYCLL EDFQGHLMAGESSMKALLTEKESLKVGLLDSTTYMDKIKNFLASIEKEKDSLSKMKIEWE NLSNCLTDMDKKLLESQIRLLEHGWEQMKQLVQKKYSQQSVGHEEFMFLMSKIQDLETSL QQQQQHLQLRLNSPEAQEGNLSMVALATELHTIKHRFSMLKGRAELQMKRIWGEKERKIL EDAISNLQKQLEALEPLNMEVENQIKKCETRYKIKEAILWVKNLLGELTPPISLLPDDVL SQIRKCKVVHDGILAKQQVVESLVEEVKDNIPNFTSYESNDLNNLLQDLQNQYQMLVLKS TQRSQQLELKLEERSKFVAIIGKVQLSLQGNETLIIPKTDTTSTEAELEQLYVALTTSQK ELQEIKSVISTHLQEQTNISKDLSVFERLFLDDRLKNLKTRANRTQRFIQNKCNEVEHKI NSYREFHEKISALQKEFDHIQHNELLLNPEVNPDVKEELYHLKNQITGIQSSILQVLKLK EVFDCIELNWDWTQLDQIQTQVLEKERELEEKIKQLNTFVAEYDKYQASLAKLKALDLQI KKRAEPVLTMPNTPPESSLLNAQVLNQRIGKAMSLYHEIIKKLSENKDFDDLFKEREIQQ LKLYAEEHNKLRQVLQQKMALQSQLKEMDEKDFKDKLENSLHVLNQIKSQLQQPLLINLQ IDYIQNEKDNCEVFQEKVQAEMDSIKAVTVIEKQSEENSSEASDVEAKLNDIEDLYMQLN ASIDSRTSVLNDAYENMTRYNEAVSRAMGIISDLETIIVSHRVDLDNPKESVEVPRQKQE ELKSTIAGIQDLTENLGTVSSLEAKRQLECTLQDLVSKNSALREAAKVKEAEVERCLDNY KRYRNINEKICTNLSQMETILGQSMCPLPVSYKEALERLEQSKALMSNLMSAKEELLKQR QVLRHLRATCTDSDSLCLLRSTSALWERWLSLLEAAKEWEMWCEELKQEWKFVHEEIERE VIILDNLQEEVPEISKAKEAASTEELLGLLDCLRQYEENVEQQQLLLALLLQRIKNIQST PESLGAVESVPASQEIMSMQERCHKLLQKAQKNKELMQNEIQERHSFTKEITTLKNLFQQ TTISFQNMELQDCPEKAEQLEELQSILKKGKLTFENIMEKLRIKYSEMYTIVPAEIESQV EECRNALEDVDEKISNEVLKSSPSYTTSRKIDEINNGLRNVEKMLQQKSKDIEKAQEIQK KMWDELDLWHSKLNELDSEVQDIVEQDPGQAQEWMDKLMIPFQQYQQVSQRAESRTSQLN KATIKMEEYHDLLKSTEAWIENTSRLLADPADYDSSKTLSHHASTLQMALEDSEQKHTLL HSVFTDLEDLSAIFETDDLAQSIQELSHQVAALQQRIIESLPQIQRMADDVVAIETEVKS MEKKVSKIKAILLSKEIFDFSPEEHLKHGEVILENIRPMKKTIAEIVSYQVELRLPQTGM KPLPVFERTNRLLQDIKLLENVTQEQNELLKIAIKQTNECNEEMEKLKQILNNYPAEFSH EHMSTDQAANLSQVQGEIEGMEKQILSLNQKKEDLVVDLKAAILNLHQHLQQKQQELEQE VLSVGASEENTGAEKDASEWTLNRTSSMSFLPALEEEAEESSLKSESGDKKAEPSSGFLS LLWKHDKDVEEDRASSSSGTIIQEAAGKISTCDSSMAQVLEPDLLNTERGPEFSLSPNQT PEGATPPIKAAATGLSDKQGAFEATVEKVRPEPAEVLHVCKNQVAELELWLHQANVAFEP ETLDADMQQVVEQQLVGCQAMLTEIEQKVASLLENCKDQGLGDSGATQQEAEALSLKLKT VKCNLEKVQMMLQEKYSEDQHSTTLKKSSERQKVLQPDNLSEFESVVTERPQFSRQKDFQ QQQVLELKPMEQKDLIKFIEFNANKTWPQYCQHDKDTTQTSSASSKTSSPQNDAPDLILS TQGQSGDKWQYLHHELSSKIRLPLSQLVQPQVTTNMSILPSVTVYNFRYPTTEELKTYTT QLEDLRQEANNLQAQENMSEEAYTNLDKKLFELFQTLIQCLSSVEDMLQTPGLFRGDVGT QQVHYETLALELKKLYLAMSDKKNDLSKAMTWPGKNASQFLDCFDNLQVYLEHTQATAAS RSKALKAGLDYTRSYQNEIKRLYDQLVKNKTSLQQSLNEISGQTIDEQLQKVDAYTVELQ NSESRVAKLRDEGERLHLPYVLLQEVYKLEDVLDSMWGLLRARYTELSCPCITESQQDAL LQGMVELVNIGKEKLAHDHLQQAKSKVALQAQIQNHKLFFQKLVADMLLIQTYSNKMLPS LMQKKETFGAEQVKEVKLLEEKSRQYGIKLQSLLQKWEEFDENYASLEKDLEILMSTLPS VSLVEETEERLVERISYYQQIKRNLDEKHARLYQTLNEGKQLVASVNCPELEGQIAKLEE QWLSLNKKIDHELHRLQTLLKHLLSYNRDSDQLTKWLESSQQTLNYWKEQSLNVSQDLDT IRSNINNFFEFSKEVDEKSSLKTAVLSTGNQLLHLKEADTATLRASLAQFEQKWTGLITQ LPDIQEKLHQLQMEKLPSRKAIMEMIDWMNNVEHQTEDEDSEHSLSSASQVKNLLQKYKE FRMEMDYKQWIVDFVNQSLLQLSTCDVESKRYERTEFAEHLGEMNRQWQRVHGALNGKIQ HLEQLLESITENENKIQILNNWMEAQEERLKTLQKPENVISVQKMLLDCQDIENQLAMKS KALDELRQNYLTSESGTVPLLEDTASKIDELFQKRNNVMNQVNELKTSMQSVLQEWKIYD KLYDEVNMMTIRFWYCMEHSKPVVLSLEALRCQVQNLQTLQDEAESSEGSWKKLQEVIGK LKEYCPSVAEIIQEKCQNTHTRWTQVNQDVADQLQRAQSLLQLWQACSSAHAEAAARLEP QETKWQQLANINTSGNNLAEVLPPALQGAKELQCEVQKTKEAFLQNSTLLDRLPQPAEPN THVLLSSQMHSLQRASYLEKMLLVKTNEFEFVLSQFKDFGDRLESLKGLITHEEENLDKL YRQEKEGNPDLFLNHVLALTAQSPDIEHLNEVSLKLPLSDVAVKTLQNVNRQWIRATATA LERCSELQGIGLNEKFLHCYEKWVQLLEKIEETLKANMADSLPALLEQQKTYEMLEAEVS INQTIADSYVTQCLQLLDTAEIEKRPEFVWKFTRLKGQWQSAAQGVRQRKSDIDELVRQW RSFTTSEGDLLRFLADTSHLLSAVKSQDCHSLHQTRSLIHELKNKEIHFQRWQTTYALTL EAGEKLLNTANLETKESVNKRISQLQDNWKDTKLQLGEMIKRFQSTTETWDQCEKKIKEL KNRLHVLKAQSKDPLPELHEELHREKELIKELEKSLANWTQNLKELHTMKTDLTQHILVD DVMVLKEQIEHLHRQWEDLCLRVAIRKQEIEDRLNSWIVFNEKNKELCAWLVQMENKVLQ TADISIEEMIEKLQKDCMEEINLFSENKLQLKQMGDRLIKASNKTRAAEIDDKLNKINDR WQHLFDVIGSRVKKLKETFAFIQQLDKNMSNLRTWLARIESELSKPVVYDVCDDQEIQKR LAEQQDLQRDIEQHSAGVESVFNICDVLLHDSDACANETECDSIQQTTRSLDRRWRNICA MSMERRMKIEETWRLWQKFLDDYSRFEDWLKAAERTAACPNSSEVLYTVAKEELKRFEAF QRQIHERLTQLELINKQYRRLARENRTDTASKLKQMVHEGNQRWDNLQKRVTAILRRLRH FTNQREEFEGTRESILVWLTEMDLQLTNVEHFSESDADDKMRQLNGFQQEITLNTNKIDQ LIVFGEQLIQKSEPLDAVLIEDELEELHRYCQEVFGRVSRFHRRLTSHAPGLEDEKEASE NETDVEDPREIQDDSWRKRGASEEPSSPQSLCQLVPPALGPERSGCETPVSVDSIPLEWD HTGDVGGSSSHEEDEEGPYYSALSDIEILENPEAYLKMTTKTLKASSGKSISEGPSWHVP DSPSCPKRRYKQMGGDRNVQPIPSDSSTPYKPAYVKLLLSPGTEGGKEDPGVLTGSAQQE DEDLAALTGQQSGAFDRWELIQAQELHNKLRKKQNLQKLNSDISNITPWLEKTGAELETL KLAEPPSDMQEMERQVKKLKEILKAFDTYKALVVSVNVNSKEFLQSESAESKELQDRVGQ LTLRWNTALGAVESWREGLRRSLMQCQDFHQLSQSLLLWLASAESRRQKAHVTDPEADPQ ALLACREELVQLEKELVERQPQVNSLQEISSTLLIKGHGEDYIEAEEKVHVIEKKLKQLL EQVSQDLVSLQRSQNPDSPLPSVDEVDHGEPLAASAPAPQAKFEAEKTTKEKNKTASRVP GPAAPESSKPQRSFLSRVFRAALPLQLLLLLLLFLACLLPSSEEDYSCTQANNFARSFYP MLRYTNGPPPT NT seq 20916 nt NT seq  +upstreamnt  +downstreamnt atgatgttgtgctcaagactgctgcccattttaattgggttgttcactttgctgctgttg atgtgggggagttctttatatattatggatgttaatttcttatcagttcacttctttaac tgtgatgaacatgatataatctcactgagtcaaaggatggcatctagtcctgtgcttccc gccgaagaccaacaggtttccttgggcattgatgatctccatttttcattgcaagcggaa caggaagacactcagaagaaaaccttcacctgctggataaactcacagttggcaaagcac acccctccctcagttgtaacagacctgttcacagacattaaaaaggggcatgtcctcctg gacctgctggaagtactctcaggacagcagttgcctcgagataaaggatctaatacattc cagtgtagaatcaatatagaaaatgctctgacattcctacaaaaccaatcaatcaagcta ataaatattcatgttactgatatcatagatggaaacccatccattgttcttggcctcatt tggacaattatactgcactttcatattgaggagcttgcccggactcttcctggcagttac agtcagccttccctggacagtgtgagtgcagttgactcctctcctacctcaagtcctcca gccaagaaatgctccaaagtccaagaaagatggcggatgtctgcaaagaaggctcttctc cagtgggctcaggagcagtgtgcctcgtatgaatctgtcaatgtgacagattttaagtca agctggagaaatgggagggctttcctggctgtcattcatgccttgcgaccagacctgatt gacatgaagagtgtgaagcatagatccaacagagacaatctgaaagaggccttcagaatt gcagaacaagaattaaaaatccccaaaatgctggaaccagaagacgtggatgttgttaat cctgatgaaaagtcgatcatgacctatgtggcacagtttctgcagtattcaaagaaggca cctgggtctggagatgaagcccagggaaaggtgaaagatgctatggtctggttagctcta caagagaagaaggtacagaaaatgctaagggattcagaaaatgagacctactgtaaaacg tatgaaagcctgctgtcctttctggagtcattcaacaaagaaaaagaacgctttttggat gtcctgacaataaaaaggaatgtagatgacctgaataaagatcagttgcagttgggagaa gcctgggatggtctcaactaccagattaacgtgtggcaaacagagttgaatcgtgtcttg ccctcacccctttatcaaatagaaacttggctccaggaggtagaaaagcttatagatgaa gatttgtcagtctcccaggattacagtgaagccatggctctaacacaagagaaaattact ttattccagagtctgatggataaatttgactgccatttgaatactctcctggcgtttgaa aatagagacgaaaaccatttgcctttggtaccccctgaaaaattggaggaaatgaaaaga cgaatcaacaacatttcggggaaaaaagtcattccacgtttagaatttcattactatgag tgctcagttcttggtttgctagaggaggtgaaatcaaaattgcttgtttggaacatcaaa tacgggagcaaagaatctgtggaattattgctggaagactggcataaatttattgaagaa aaagagttcctagctcaacttgaaacttcgtttcaaaaatgtgaagaaattcataacaac ttggctggagaatatccaaatattagtaaacaatatacgatggtgaaatatcatttttcc atgtatagagaaaatatacttaatgtgaagtccactctacaaaaagttctggcatgttgg gctacttatgtggaaaaccttcgtttactaaaggcttgttttgaggagacaaagaaggaa cagatgaaagaggttccctttgagacactctcccagtggaatctacaacatactacttta aatgaagtgggaaatttcttatttcaagtcagcaatgatgaagttggattgtctatttct aaagaactgaagaggctgaataaaagatggagaaagcttattacaaaagctcagcctgaa gtgaacctgccacttatgaaattacaagatgagccctttcttgacaattctggaaatatt cagctatccaaggaagaaaatctagctgttggtttttcaacagataggtcaagccaactt cctgaaaaccacaatcagaatattatggctggggaagtacatgaaaaagaaaatgaagac ttttcagggccactgaaagtggctaaagaggttgaaaagctcattggacaagtggaaacc tgggaggcagaaaccacgtctgttttggatcttctgagacagcaggatgatgtagagacc tcagtggaagaatctttgcagcatcttattgccaaaggctctatgtatgaagagcttgta tctagaattgaagacactttacaaatggatgtacaacatgtttcaagtcaggagtctctc caacatgtcctcacagctggacttcaggcaaagattcaagaagctaaagagaaagtccag atcagtatgataaaattagtagctgtgttgaagaactcaactgatgtttcccaagacctg gatgtcaggctgaaggtggaagaaacacagaaggaacttgaatcatacattacaagggct gagcagttacttgggcaaaaagagagccagaggggactaattacaaaatacaaggaagca ctgataatttctaatactaaaagtctggccaagtatttgaaagctgttgaagaactgaaa aataatgtaactgatgatgtaaagctgtctttggaagaaaagagtagagacatttgtgcc aagtgggagtctcttcatcatgaaatgtccctgtatattcaacaactaaaaatagacatt gaaaaaggaaaacttagtgatagtattgcaaaacttgaaaagcaaatcaataaagaaaag aagctaattcgcagaggaaggaccaagggtctcatcaaagaacatgaggcctgcttttct gaggaaggcagcctgtaccagcttgatcatcacatggatgtcctgcgggagctgtgtgag gagctgacttctcagaagagtcaacaagaagtgaggagagcgctcaaagattacgagcag aagatagagaggcttcggaaatgtgcttccgagattcatatgacactgcagcccaccttg ggaggcacatcgaaaaacaagggaaccacggatgcatctaagaatggaggagggaatacc ctcagcgaggtgccatctgcaaaatcagacaatcagccgtcagctgaaaaggcaatggaa ttggttcagaattttaacctggaatccaagttgaagctgcaacaggaggaaagcatcatg gagaaatatgaaaagggtcacagtacctctattgacagtttactagagaggtatgataca cacaaaggcactcttgaactttacctgcaaaacagcattgccagaattacttctgatttc tctagtgacaaggaaaggagtagtgtttgtctccaggacaaactgacagatctacaggtc ttaaaaaatgaaactgatgcttgctggaaagagtttgaaatcacttcattgaagttagaa gagcttgagagtgacattaagaagccttttatagttaaggcaagagacaaattaaaggag aaagaaagagagcttcagatgactcttaagtccagaatggagtctttagagactgtactg aagatggtgttacccatggagaaggagtcactgcttctctgtgacacagacctgctcctc cgtgaaatggccattcaggaatttcatctcactgatgctgatgacatttatcaaaacctg aggaatatccaagattccgtagtaaaacagattgaaacatgtaagaatttgggacagtca ggcaactttgcattaaaggaattgcacccccttgacctgcatgcagcacagaacattatt ctgaaacacagaactcaactggaagagatgaaccacagagtacagaagagtaaagatgct cttgaagctctggaagattttttggcttctctgagagcagctgaactctctagtgagctt cttacagaccattcagcctcagattcacagggggtaccggcaaatactttgacggtggaa aataaagagagagaaattcatcggatgagagacaaggccagacatttggatgagcatttg aagatgcttggtataagcattaaagacagtgaacagggtgaaaacacctcctgtgaaaaa cttctggatgctttgtccaaaaacttatctgagacacgttctggtgggcaggaggaagtc actgaagaagacaaattactaggggcttgtgtttctaagaatgatgaactcctgaaaaat attcaagatgtgcacaatcaaatcagtaaaattggcctgaaggatccgactgttccagca ataaaacaaaggagaaaatcgttaatcagactggataaggacctagatgaatatgaagaa gagaagaaacatttgcaagaaatggtgaattctcttccgcaattcaaagatggcagagac aaagccctgagtcaaaggtgccaggacacagcagtcttgtgggagaatgtaaaaaccttg gtcacagaatgccttgaccaatgtgaaagagttctggagctcttaaaacagtatcagaat tttaaaagtgtcctgacagcattgattcaaaaagaagagaatgtcctctctgtccaggct tcctacatgggaaaggagaacttgaagaaaaggatagcagagattgaagttgttaaagaa gaatttaatgaacacttagaagttgtagacaagattcaccagatctgcaaaaatctgcag tttcatctgaataaaatgagaacctttgaagagcctccctttgagaaagaagctaatatt attgtggatagatggcttgatataaatgagaagacagaggactactatgacaatcttggt cgagctctagctttatgggacaaactttttgacttaaaaaatggaattgatgagtggact gaaaaggtccttcaaaaattggaattacatcaactgactgaagaggaaagagaaaaactg aaggaagagttacaagtccatgaacaaaaaccttcagaattttctaaaagagtggctaaa atacaattcctgcttcaaagcagtgaaatacctcttgaattacaggtgatggagtcttct attttgaacaagatagaacgtgtgaaaatgtgtttaacgggaggatcccactgtggtgca atcagcggcagcacagctgagctaagggaagatcttgaccaggccaagacccagattgga atgactgagtctctcttaaatgccttgtcgccttccgacagcttggagatcttcactaaa ctcgaggagattcaacaacaaattctacagcagaagcacagtatgatattacttgagaat caaataggttgtctgactcctgaactctctgaattaaaaaagcaatatgaaagtgtcagt gatttatttaataccaaaaaaagtgttttgcaagatcacttttctaagttactgaatgat cagtgcaagaactttaatgactggtttggcagcattaaaatgaaccttaaggagtgtttt gaaccatcagaaacaaaaaagtgtgtggaacaaaaactacaaaaactttctgatttcttg actcttgaaggaagaggcagtgaaatacagcaagtgggaactgtactgaatcatgtgaaa aaacatctgcccaaagcacctgttaagaagcttaacagttggatcgtaagtcaagaagtt gaattagaaaaaatggagtccatatgccaggcacgagcaaaggagcttgaagagtgcttg cagcagctactgagactccataatgaccacagaaacctgagtaagtggttgactaatcaa gaagaaatatggaaagaaatggaaggaacacgagagaaaacggagctattttgccaagct ctagctagaaagagagaacaattcgaatcaatggcccagttgaacaactctgtgaagcaa tatgggattactgaagaagaagaaatagtaacggaatcaacacatttgattgatagatac cagacattattgagacaaatatgtgaaactgacaaagaggataagttacctcctgccgag gaccagagttttaatgatcttgcacatgatgtaattcattggataacagggattaaagaa tcccttatggttttgaattcatctgaaggcaaaatgccacttgaggaaagaatccataaa ataaaggaaatcattttactaaaacctgaaggggatgctaaaatacaggccatcatgagt caggctgagagcagcaagactccagtggttccaaagaccctcactgatatcaagaaccag tgggacaacacactccatttggccaacacatatctaagccatcaggaaaagcttctacta gaaggcgagaagtatttgcaaagtaaggaggatctgagattaatgctcacagaactgaaa aagaaacaagaagtgggctttgctctgcagcctggtttgcaggagaagaaagctcaatta aaaatttataagaagttcctccagaaagcacaggatttaacattcttactagaggagtta aaatctcaaggaaattacctcttagagtgcactaaaaatcccaactttagtgaagaaccg tggctggaaatcaagcatctacatgagagtcttcttcagcaactgcaggattctgtgcag aaactagaaggtcatgttcaagaacacgactcttaccagctttgcgtcacagacctgaac actgcattggactatatcgctaaggaatttgtctgtttttctgataggcctgtagatgaa agagcagttgaggaaaaactgcagaaactgcaggacctagagaatagtctccatttacaa gatggcccattagagaagattttaactttagcaaagtccgtcaagcaaaatacatcttca gcaggacagaagattattaaagatgatataaaatcactgaagtgtaaacaaaaagatttg gaaaacagacttgaatctgctaagcaggagatggaaaactgtctcaacagcattctcaaa tcaaaatgctcaacagaaaacaaagcaaagtttcctctgccaggcagagaggagcaggtc 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ctgggagacagtggagccactcaacaggaggctgaagcactttccttgaaactgaaaact gtgaaatgcaatttggaaaaagtccaaatgatgcttcaggagaaatacagtgaggaccag cattctaccacactaaagaaatcttcagagcgtcagaaagttctccaaccagataacctt tctgaatttgaatctgttgttaccgaaaggccacaattcagtagacaaaaagatttccag cagcaacaggttttggagttaaaaccaatggaacagaaagatttaatcaaattcatagaa tttaatgctaacaaaacatggccccagtattgccagcatgataaagatacaactcagaca tcatctgcaagcagtaaaacatctagcccccaaaatgatgctccagacttgatcttgtca acccagggccaaagtggagataagtggcaatatttacaccatgaactctcatcaaaaata aggctccctctctctcagcttgtacagccccaggttaccacaaatatgagtattctaccc agtgtgactgtgtataactttagatacccaacaaccgaagaactgaaaacttacaccacc cagcttgaagacctgcgtcaagaagcaaataatcttcaggcacaggaaaacatgtcagaa gaagcgtacacgaatctggataagaaattatttgaactgtttcagaccctcattcagtgc ctgagcagtgtggaggacatgctgcagacacctgggctcttcagaggggatgtgggtacc cagcaggtgcactacgagacattggctcttgagttgaaaaaactttacttagctatgagt gacaagaagaatgacctttcaaaagccatgacttggcctggcaagaacgccagccagttc cttgactgttttgataacctccaagtctacctggagcacacccaggctacagctgcctct 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aaacatctgctcagttataacagggattcagatcagttaaccaagtggttggagtcttct cagcaaactctgaactattggaaagagcagtccctcaatgtgtctcaggacctggacaca atcagaagcaacataaacaatttttttgagttttcaaaggaagttgatgaaaagtcctcc ttgaagactgcagttctaagtactggaaaccaactccttcacctgaaggaggctgatacg gcaacactgagagcttctttggcacagtttgaacaaaaatggacagggctcataactcaa cttccagacatccaagaaaaacttcaccagcttcagatggagaaattgccatctcgtaaa gcaatcatggaaatgattgactggatgaacaatgtggaacatcaaactgaagatgaagac tctgagcattcactgagttctgcatctcaagttaaaaatcttcttcagaagtacaaggag tttagaatggaaatggactataaacaatggatagttgactttgtaaaccagtcattactt cagttaagcacctgtgatgtagaaagtaagcgctatgagagaacagagtttgcagagcac ctgggagagatgaaccgccagtggcagcgggtccacggagccctgaacggcaagatacaa catttagaacaacttttggaaagtattactgagaatgaaaacaaaatacagattctgaac aactggatggaggcccaagaggagagactgaaaactttacaaaaacctgaaaatgtgatc tcggtacagaagatgctcctggattgtcaggatatagaaaatcaacttgcaatgaaatcc aaagcattggatgagttgagacaaaattacctgacttcggagagtgggacagtgccattg ttggaagacacagcatccaaaattgatgagctatttcaaaagagaaacaatgttatgaac 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ttaagagtggccatacgcaaacaggagatagaagatagactcaattcatggattgtgttc aacgaaaaaaacaaagagttgtgtgcatggctggtgcagatggaaaacaaagttctccag acagcagatattagtattgaagaaatgattgaaaagctccagaaggactgcatggaagaa ataaatttgtttagtgaaaacaagttacaattaaagcaaatgggcgaccggctgatcaag gccagcaacaagacaagagcagctgagatcgatgacaagctcaacaaaatcaatgaccgt tggcaacatctttttgacgtcattggctcaagggtgaagaagttgaaggagacctttgct tttattcagcagttagacaaaaacatgagcaaccttcgcacctggttggctcggatcgag tctgagctttctaagcccgtggtttatgatgtctgtgacgatcaagagatccagaagagg cttgctgagcagcaggacctgcagcgagacattgagcagcacagcgcaggggtggaatct gtgtttaacatctgtgatgtcctcctgcatgactcagatgcctgtgccaacgagaccgag tgcgactccatccagcagaccaccaggagcctggacagacgctggaggaacatctgtgcc atgtccatggagcggcggatgaaaattgaggagacgtggaggctgtggcagaagtttcta gatgattactcccgctttgaggactggctcaaggctgccgagaggacagcggcctgtccg aattcctccgaggtgttgtacacggttgccaaagaggagctgaagaggtttgaggccttc cagcggcagatccacgagaggctgacgcagctggagctcatcaacaagcagtaccggcgg ctggcccgtgagaaccgcaccgacacggccagcaaactgaagcagatggtgcatgagggc aaccagcgatgggacaacctccagaagcgggtcacggccatcctgcggagactcagacat ttcaccaaccaaagggaggaatttgaggggaccagggagagcatcctggtgtggctcacg gagatggacctacagctgaccaacgtggagcacttctcagagagcgatgctgacgacaag atgcgccagctgaacggtttccagcaggagattacgttaaataccaacaagattgatcag ctcatcgtttttggggagcagctcattcagaagagcgagcccctggacgccgtgctgatt gaggacgagctggaggagctgcaccgatactgccaggaagtgttcggcagggtctcccgg ttccaccggaggctcacctcccacgcgccgggcttggaagatgaaaaggaggcctctgag aacgagacagacgtggaagaccccagagagatccaagacgactcttggcgtaaaagggga gcaagtgaggagccctcatccccgcagtccctttgtcaactggtgcccccagcgctgggg cccgagcgctctggctgcgagacccctgtcagcgtggactccatcccactggagtgggac cacacaggcgatgtggggggctcctcctctcacgaggaagacgaggagggcccctactac agtgcactgtcagatatagaaatccttgaaaatcctgaggcatatcttaaaatgaccaca aaaactttgaaagcgtcttctggcaaatccatttctgaaggcccctcgtggcatgttcct gacagcccttcctgtcccaagcgtcgctacaaacaaatgggaggtgacaggaatgttcaa cccatcccctctgattccagcaccccttataaaccagcctatgtaaaactgctgttgtct ccagggactgaaggtggcaaggaagatccaggggttctgactggcagtgcacagcaggaa gatgaagacctggctgccctcactggtcagcagtcaggtgcctttgacagatgggaactg atccaagcacaagaacttcacaataagctcagaaaaaaacaaaacctgcagaagctgaac tctgatatcagcaacatcaccccttggctggaaaaaactggagcagagctggagacgtta aagctggcagaacctccctctgatatgcaggaaatggaacgccaagtgaagaagctgaag gagatactgaaagcctttgacacctacaaggccttagtggtctccgtcaacgtgaacagc aaagaatttctgcagagcgagagcgccgagtccaaagaactccaagatagagtcggccag ctgaccctgcgctggaacacggccctgggcgcggtggagagctggagagagggtttgcgg cggtcgctcatgcagtgccaggactttcaccagctgagtcaaagtctgctgctgtggtta gcgagtgctgagagccggcggcagaaggctcatgtcaccgacccggaggcagacccccag gctctcctggcgtgtcgggaagaactcgtgcaactggaaaaggagctagtggaacgtcaa cctcaagtaaattccttacaagagatttccagcaccctgcttatcaaggggcatggagaa gactacattgaggctgaagagaaggtccatgttattgagaagaaactcaaacagttactt gagcaagtgtcccaagacttagtgtccttgcagcgaagccagaacccagactcacctctg cccagcgtggacgaggtagaccacggagagcctctggcagcatctgcgccagctccccaa gccaagttcgaagcagagaaaactacaaaagagaagaacaagaccgccagcagggtgcct ggtcccgctgcccctgagagctccaagccccagcgctccttcctttctcgggtgttcagg gcagcgctgcccctccagctgctcctgctgctgctgctgttcctggcctgcctgctgccc tcctccgaagaggactacagctgcactcaggctaacaactttgccaggtccttctacccc atgctgcggtacaccaacgggccacccccaacatag

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