Bison bison bison (American bison): 104994471 Help Entry 104994471         CDS       T08726                                  Symbol PLA2G4B Name (RefSeq) cytosolic phospholipase A2 beta   KO K16342   cytosolic phospholipase A2 [EC:3.1.1.4] Organism bbis  Bison bison bison (American bison) Pathway bbis00564   Glycerophospholipid metabolism bbis00565   Ether lipid metabolism bbis00590   Arachidonic acid metabolism bbis00591   Linoleic acid metabolism bbis00592   alpha-Linolenic acid metabolism bbis01100   Metabolic pathways bbis04010   MAPK signaling pathway bbis04014   Ras signaling pathway bbis04072   Phospholipase D signaling pathway bbis04217   Necroptosis bbis04270   Vascular smooth muscle contraction bbis04370   VEGF signaling pathway bbis04611   Platelet activation bbis04664   Fc epsilon RI signaling pathway bbis04666   Fc gamma R-mediated phagocytosis bbis04724   Glutamatergic synapse bbis04726   Serotonergic synapse bbis04730   Long-term depression bbis04750   Inflammatory mediator regulation of TRP channels bbis04912   GnRH signaling pathway bbis04913   Ovarian steroidogenesis bbis04921   Oxytocin signaling pathway bbis05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:bbis00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     104994471 (PLA2G4B)    00565 Ether lipid metabolism     104994471 (PLA2G4B)    00590 Arachidonic acid metabolism     104994471 (PLA2G4B)    00591 Linoleic acid metabolism     104994471 (PLA2G4B)    00592 alpha-Linolenic acid metabolism     104994471 (PLA2G4B)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     104994471 (PLA2G4B)    04014 Ras signaling pathway     104994471 (PLA2G4B)    04370 VEGF signaling pathway     104994471 (PLA2G4B)    04072 Phospholipase D signaling pathway     104994471 (PLA2G4B)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     104994471 (PLA2G4B)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     104994471 (PLA2G4B)    04664 Fc epsilon RI signaling pathway     104994471 (PLA2G4B)    04666 Fc gamma R-mediated phagocytosis     104994471 (PLA2G4B)   09152 Endocrine system    04912 GnRH signaling pathway     104994471 (PLA2G4B)    04913 Ovarian steroidogenesis     104994471 (PLA2G4B)    04921 Oxytocin signaling pathway     104994471 (PLA2G4B)   09153 Circulatory system    04270 Vascular smooth muscle contraction     104994471 (PLA2G4B)   09156 Nervous system    04724 Glutamatergic synapse     104994471 (PLA2G4B)    04726 Serotonergic synapse     104994471 (PLA2G4B)    04730 Long-term depression     104994471 (PLA2G4B)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     104994471 (PLA2G4B)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     104994471 (PLA2G4B) Enzymes [BR:bbis01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.1  Carboxylic-ester hydrolases     3.1.1.4  phospholipase A2      104994471 (PLA2G4B) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PLA2_B cPLA2_C2 C2 BMF Motif Other DBs NCBI-GeneID:  104994471 NCBI-ProteinID:  XP_010846359 Ensembl:  ENSBBBG00000014181 UniProt:  A0A6P3I3I5 LinkDB All DBs Position Unknown AA seq 907 aa AA seqDB search MGPGLGRAGPFGSRLGLKVSSQPPFWAHQLAVSLFLHPLQAKVPGTCLLTIRVLQAHGLP SKDLVTSSDCYVTLWLPTASSHQLQTRTVKNCRNPVWNQSFHFRIHSQIKNIVYLRVFDQ DLLTTDDPLLSVLFDVGTLQAGESRRESFSLSPQGEERLEVEFRLQNLTDGAECLFSNGI LVARELSCLHVRLEKAGDLQESEGRVQLVVPGSCEGPQEAFVGAGSFRFHWPACWEQELS IHLQDAPQEQLKVPLRALPSGQVVRLVFPTSQEPLMKVELKNEEGPRDLAVRLGCGPCAE EQAFLSRRKQVVAKALQQALQLDRDLREDEIPVVAVMATGGGIRAMTSLYGQLAGLKALG LLDCVSYITGASGSTWALANLYEDPEWSQKDLAGPIESLKTQVAKSKLGVLAPRQLLRYQ QELAERARLGHPACFTNLWALINEALLHDEPHDHKLSDQREALSRGQNPLPIYCALNTKE QNLTTFEFGEWCEFSPYEVGFPKYGAFIPSELFGSEFFMGRLTKQLPESRICFLEGIWSN LYAANLQDSLYWSSEPSQFWDRWAQARASLDKEQVPLLKIEEPPTVAGRIAEVFTDLLTR RPLAQATHNFLRGFSFHKDYFQHPHFSAWKATKLDGLPNELTPAEPYLCLLDVGYLVNTS CPPLLPPTRDVDLILSLDYNLHGAFQQLQLLGRFCQEQGIPFPPISPSPEEQCQPQECHL FSDPARPDIPAVLHFPLVNASFRDHSAPGVRRTAEEQAAGEVNLSASDSPYHYSRGTYSL EDTDKLLHLTQYNICNNQERLLEALREAMRRRRQRTQRPSGQISLGFPCRVGCELMAASV PPKLTLFKQRGSHLGQGMRAWALLLQPWPCPDDSQVMPASTPVLLTRRLSRRAASCPTVG VARRGTR NT seq 2724 nt NT seq  +upstreamnt  +downstreamnt atgggcccaggactgggcagggctggtccttttggttcaagattaggcctcaaggtgtca tcccagcctcccttttgggcccaccagctggccgtaagcctgtttctccatcctctgcag gcaaaggtgcctgggacctgcttactcaccattcgtgtcctgcaggcccatggcctgccc tccaaggacctcgtgacctcctctgactgctacgtgaccctgtggctgcccacggcctcc agccaccagctgcagacgcgcacagtcaagaactgcagaaaccccgtctggaatcagagc tttcacttccgaatccatagccagatcaagaacatcgtgtatcttagagtctttgaccag gaccttctgaccacggatgaccccttgttgtcagtgctatttgacgtggggaccttgcag gctggggagtcccggcgcgagagcttctcgctgagccctcagggtgaggaacgcctggaa gttgaatttcggctgcagaatctgactgatggtgctgagtgcctcttcagcaatggcatc ctagtggcccgggagctctcctgcttgcatgttcgactagagaaggcaggggacctgcag gagtcggagggtagagttcagcttgtggttcccgggtcctgtgagggtccacaggaggcc ttcgtgggtgctggctccttccgcttccattggccggcctgctgggagcaggagctgagt attcacctgcaggatgccccccaagagcagctgaaggtgcccctgagggctctgccctct ggccaagtggtgcgactcgtcttccctacatcccaggagcccctgatgaaagtggagctg aaaaatgaagaaggacccagggacctggctgtgcggctgggctgcgggccctgtgctgag gagcaggccttcctgagcaggaggaagcaggtggtggccaaggccctgcagcaggccctg cagctggacagagacctgcgggaagatgagatcccagtggttgctgttatggccactggt ggtggtatccgggccatgacctcactgtatgggcagctggctggcctaaaggcgcttggc ctcttggattgtgtctcctacatcacgggggcctcgggctccacctgggctttggccaac ctctatgaggatccagagtggtctcagaaggacctggcagggcccatcgagtcactgaag acccaggtggccaagagcaagctgggtgtgctagcccccaggcagctactgcggtaccag caggagctggctgagcgcgcccgcctgggccacccggcctgcttcaccaacctgtgggcc ctcatcaacgaggcgctgctacatgacgagcctcatgaccacaagctctcagaccagcgg gaggccctgagtcgaggccagaaccccctgcccatctactgtgctctcaacaccaaggaa cagaatctgaccacctttgaatttggggagtggtgtgagttctccccctacgaggtcggc tttcccaagtacggtgccttcatcccctccgagctcttcggctctgagttcttcatgggg cgcctgacaaaacagcttcctgagtcccgcatctgcttcctggaaggtatctggagcaac ctgtatgcagccaacctccaggacagcctatactggtcatccgagcccagccagttctgg gaccgctgggcacaagctcgggccagcctggacaaggagcaggtcccccttctgaagata gaagagcctcccacggtggccggcaggatagcggaggttttcaccgaccttctgacgcgg cgtccacttgcccaggccacccacaatttcctacgtggcttctccttccacaaggactat tttcagcatcctcacttttctgcctggaaagctaccaaactggacggcctccccaacgag ctgacacctgcagagccctacctttgcttgctggatgttgggtaccttgtcaataccagc tgcccacccctcctgccgcccacacgggatgtggacctcatcctttcgctagattacaat ctccatggagccttccagcagctgcagcttctgggtcggttctgccaggagcagggcatc ccgttcccacccatctcgcccagccctgaggagcagtgccagccccaagagtgccacctc ttctcggaccctgcccgccctgacatccctgccgtgctgcacttccctctggtcaacgcc tccttcagggaccactctgcccccggggtccgacggacagccgaggagcaggctgctggg gaggtgaacctgtctgcatccgactccccctaccactactcgagggggacctacagcctg gaggacacggacaagctgctccacctgacgcagtacaacatttgcaacaaccaggagcgg ctgctggaggccctgcgtgaggccatgcggaggcggaggcagcgcacgcagcgcccgagc gggcagatcagcttgggcttcccttgcagagtgggctgtgagctcatggccgcatctgtt ccacccaagctcacgctcttcaagcagagaggaagccatcttggccagggtatgagggcg tgggccttgctgctgcagccctggccctgcccagatgactcacaggtaatgccagccagc acccctgtcctcctcacccggagactcagtcgaagggctgcttcctgtcccacagtaggg gtggcaagacgtgggaccagatga

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