Bison bison bison (American bison): 104994676
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Entry
104994676 CDS
T08726
Symbol
PDHA2
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
bbis
Bison bison bison (American bison)
Pathway
bbis00010
Glycolysis / Gluconeogenesis
bbis00020
Citrate cycle (TCA cycle)
bbis00620
Pyruvate metabolism
bbis00785
Lipoic acid metabolism
bbis01100
Metabolic pathways
bbis01200
Carbon metabolism
bbis01210
2-Oxocarboxylic acid metabolism
bbis04066
HIF-1 signaling pathway
bbis04922
Glucagon signaling pathway
bbis05230
Central carbon metabolism in cancer
bbis05415
Diabetic cardiomyopathy
Module
bbis_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
bbis00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
104994676 (PDHA2)
00020 Citrate cycle (TCA cycle)
104994676 (PDHA2)
00620 Pyruvate metabolism
104994676 (PDHA2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
104994676 (PDHA2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
104994676 (PDHA2)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
104994676 (PDHA2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
104994676 (PDHA2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
104994676 (PDHA2)
Enzymes [BR:
bbis01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
104994676 (PDHA2)
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Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
104994676
NCBI-ProteinID:
XP_010846626
Ensembl:
ENSBBBG00000021816
UniProt:
A0A6P3HVN1
LinkDB
All DBs
Position
Unknown
AA seq
391 aa
AA seq
DB search
MKKMLTAAVSRVLSGVTQKPASRVLVASCKYSNNATFEIKKCDLYRLEEGPPVTTVLTRE
DGLKYYKMMQTIRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPTDHVITSYR
AHGLSYTRGLTVRSILAELTGRRAGCAKGKGGSMHMYAKNFYGGNGIVGAQGPLGAGVAL
ACKYKGNNEVCLTLYGDGAANQGQISEAYNMAALWNLPCIFICENNRYGMGTSVERAAAS
TDYYKRGNFIPGLRVDGMDILCVREATKFAADYCRSGKGPILMELLTYRYHGHSMSDPGI
SYRTREEIQSVRSKSDPIMLLKDKMVNNQLASVEELKEIDVEVRKEIDDAAQFAMTDPEP
PLEELGHHIYSSNPPFDIRGANQWIKFQSIS
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atgaagaagatgctgactgctgctgtctctcgcgtgctgtctggtgtcacccagaagccc
gctagcagagtgcttgttgcctcctgtaaatattcaaacaatgctacctttgagattaag
aaatgtgatctttatcggttggaagagggtccccctgtcaccaccgtgctcacccgggag
gatggactcaaatactacaagatgatgcagactattcgtcgaatggaactgaaggcagat
cagttgtataaacagaaatttattcgtggtttctgtcacttgtgtgatggtcaggaagct
tgttgtgtgggtcttgaggctgggataaatcccacggatcatgtcattacatcctatcgg
gctcacggcttaagttatacgcggggacttactgtccgatcaattcttgcagagctgacc
ggacgaagagctggttgtgctaaaggaaaaggagggtccatgcatatgtatgccaagaac
ttctatgggggcaacggcattgtcggcgctcagggaccactgggagctggtgttgctttg
gcctgtaaatacaaggggaataacgaggtgtgtttgactctgtatggcgatggcgcagct
aatcagggtcagatatctgaagcttacaatatggcggctttgtggaatttaccttgcatt
ttcatctgtgagaataaccgctatggaatgggaacatctgtggagagagctgcagccagc
actgattactacaagagaggcaattttatccctggactaagagtagatggaatggatatt
ctatgtgttcgggaggcaactaagtttgcagctgactattgtagatctggaaagggaccc
atactgatggagctgctgacataccgttatcatggacacagtatgagtgatcctggaatc
agttaccgtacacgagaagaaattcagagtgtaagaagtaagagtgatcctattatgctt
ctcaaagataaaatggtaaacaaccagcttgccagtgttgaagaattgaaggaaattgat
gttgaagtgaggaaagaaattgatgatgcagctcagtttgctatgactgatccagaacca
cctttggaagaattaggccatcacatctacagcagtaatccaccttttgatattcgtggt
gcaaatcagtggatcaagtttcagtcaatcagttaa
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