Bison bison bison (American bison): 104994875
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Entry
104994875 CDS
T08726
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X1
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
bbis
Bison bison bison (American bison)
Pathway
bbis00270
Cysteine and methionine metabolism
bbis00480
Glutathione metabolism
bbis01100
Metabolic pathways
bbis01240
Biosynthesis of cofactors
bbis04216
Ferroptosis
Module
bbis_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
bbis00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
104994875 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
104994875 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
104994875 (GCLC)
Enzymes [BR:
bbis01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
104994875 (GCLC)
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Ortholog
Paralog
GFIT
Motif
Pfam:
GCS
GCS2
SANT_DAMP1_like
Motif
Other DBs
NCBI-GeneID:
104994875
NCBI-ProteinID:
XP_010846863
Ensembl:
ENSBBBG00000015998
UniProt:
A0A6P3HWB0
LinkDB
All DBs
Position
Unknown
AA seq
585 aa
AA seq
DB search
MLVSFDHEKKKAQLVLSGEELLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGT
MSEFNTVEDNMRKRRKEATSLLGENQALCTITSFPRLGCPGFTLPEFKPNPVEGGASKSL
FFPDEAINKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPAPFIETFPEDEEATKASKP
DHIYMDAMGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDI
DCRWGVISASVDDRTREERGLEPLKNNHYRISKSRYDSIDSYLSECGEKYNDIDLTKDKE
IYEQLLQEGLDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKP
PPPNSDIGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVA
QKRDAVLQELFYFRKDICKAGGNAVVDGCGKAAGRAEPAAEEYALMTIDTIINGKEGVFP
GLIPVLNSYLESMEVDVDTRCSILNYLKLIKKRASGELMTVAKWMREFIAKHPDYKQDSV
ITDQMNYSLLLKCNQIANESCECPELLGPAFRKVRYSGSKTDSST
NT seq
1758 nt
NT seq
+upstream
nt +downstream
nt
atgttggtgtcttttgatcatgaaaagaaaaaagcccaactggtcctgtctggagaggaa
cttcttgaaactctgcaagaaaagggggaaaggacgaacccaaaccatccgaccctttgg
agaccagaatatgggagctacatgatcgaggggacacccgggcagccgtacggtgggacc
atgtctgaattcaacacagttgaggacaacatgaggaaacggcgcaaagaagccacatct
ctcctgggggaaaaccaggccctctgcacgatcacttcctttcccagattaggctgccct
gggttcacgctgcccgaattcaaacccaacccggtggaaggaggagcttccaagtccctt
ttctttcctgatgaagccatcaacaagcacccgcgcttcagcacgctcaccaggaacatc
cggcaccggaggggcgagaaagtggtcatcaatgtgcccatctttaaggacaagaacacc
ccagctccatttatagagactttccctgaggacgaggaggccacgaaggcctctaagccc
gaccacatttacatggacgccatgggcttcgggatgggcaactgctgcctacaggtaacg
ttccaagcctgcagcatatctgaggccagatacctttacgatcagttggctaccatctgc
ccaattgtcatggctttgagtgctgcgtcgcctttttaccgaggctacgtgtcagacatt
gattgtcgctggggcgtgatttccgcgtctgtagatgatagaactcgggaggagagagga
ctggagccactgaagaacaaccactataggatcagtaagtcccgatacgattcgatagac
agttacttgtctgagtgtggtgagaaatacaatgacattgacctgacaaaagacaaagaa
atctacgaacagctgttgcaggaaggcctcgaccacctgctggcccagcacgtggcgcat
ctcttcatcagagacccgctgactctgtttgaagagaaaatccacctggatgatgccaac
gagtccgaccactttgagaatattcagtccacaaattggcagacaatgcgattcaagcct
cctcctccaaactctgacattgggtggagagtggaattccggcccatggaggttcagctg
acagacttcgagaactccgcgtatgtggtgttcgtggtgctgctcaccagggtgatcctg
tcctacaaactggactttctcatcccgctgtccaaggttgatgagaacatgaaggtcgcc
cagaagcgagatgccgtcctgcaggaactgttttatttcaggaaagacatttgcaaagca
ggtggcaatgccgtggtggacggctgcggcaaggccgcgggcagggcggagccagcggcg
gaggagtacgcgctcatgaccatcgacaccatcatcaacggcaaggaaggcgtgttcccc
gggctgatccccgtcctgaactcctacctggagagcatggaggtggacgtggacaccagg
tgcagcattctgaactacctgaagctcatcaagaagagggcgtccggagaattaatgaca
gttgccaaatggatgagggagtttatcgcaaagcatcccgactacaagcaggacagtgta
ataactgaccagatgaactatagccttcttctaaagtgtaatcaaatcgcaaacgaatcg
tgtgagtgcccagagttactcggaccagcgtttaggaaagtcaggtacagtggaagtaaa
accgactcttccacttag
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integrated database retrieval system
