Bison bison bison (American bison): 104997112
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Entry
104997112 CDS
T08726
Symbol
CACNA1D
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1D isoform X1
KO
K04851
voltage-dependent calcium channel L type alpha-1D
Organism
bbis
Bison bison bison (American bison)
Pathway
bbis04010
MAPK signaling pathway
bbis04020
Calcium signaling pathway
bbis04022
cGMP-PKG signaling pathway
bbis04024
cAMP signaling pathway
bbis04218
Cellular senescence
bbis04260
Cardiac muscle contraction
bbis04261
Adrenergic signaling in cardiomyocytes
bbis04270
Vascular smooth muscle contraction
bbis04530
Tight junction
bbis04713
Circadian entrainment
bbis04723
Retrograde endocannabinoid signaling
bbis04724
Glutamatergic synapse
bbis04725
Cholinergic synapse
bbis04726
Serotonergic synapse
bbis04727
GABAergic synapse
bbis04728
Dopaminergic synapse
bbis04911
Insulin secretion
bbis04912
GnRH signaling pathway
bbis04921
Oxytocin signaling pathway
bbis04924
Renin secretion
bbis04925
Aldosterone synthesis and secretion
bbis04927
Cortisol synthesis and secretion
bbis04929
GnRH secretion
bbis04930
Type II diabetes mellitus
bbis04934
Cushing syndrome
bbis04935
Growth hormone synthesis, secretion and action
bbis04973
Carbohydrate digestion and absorption
bbis05010
Alzheimer disease
bbis05020
Prion disease
bbis05022
Pathways of neurodegeneration - multiple diseases
bbis05031
Amphetamine addiction
bbis05207
Chemical carcinogenesis - receptor activation
bbis05410
Hypertrophic cardiomyopathy
bbis05412
Arrhythmogenic right ventricular cardiomyopathy
bbis05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
bbis00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
104997112 (CACNA1D)
04020 Calcium signaling pathway
104997112 (CACNA1D)
04024 cAMP signaling pathway
104997112 (CACNA1D)
04022 cGMP-PKG signaling pathway
104997112 (CACNA1D)
09140 Cellular Processes
09143 Cell growth and death
04218 Cellular senescence
104997112 (CACNA1D)
09144 Cellular community - eukaryotes
04530 Tight junction
104997112 (CACNA1D)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
104997112 (CACNA1D)
04929 GnRH secretion
104997112 (CACNA1D)
04912 GnRH signaling pathway
104997112 (CACNA1D)
04921 Oxytocin signaling pathway
104997112 (CACNA1D)
04935 Growth hormone synthesis, secretion and action
104997112 (CACNA1D)
04924 Renin secretion
104997112 (CACNA1D)
04925 Aldosterone synthesis and secretion
104997112 (CACNA1D)
04927 Cortisol synthesis and secretion
104997112 (CACNA1D)
09153 Circulatory system
04260 Cardiac muscle contraction
104997112 (CACNA1D)
04261 Adrenergic signaling in cardiomyocytes
104997112 (CACNA1D)
04270 Vascular smooth muscle contraction
104997112 (CACNA1D)
09154 Digestive system
04973 Carbohydrate digestion and absorption
104997112 (CACNA1D)
09156 Nervous system
04724 Glutamatergic synapse
104997112 (CACNA1D)
04727 GABAergic synapse
104997112 (CACNA1D)
04725 Cholinergic synapse
104997112 (CACNA1D)
04728 Dopaminergic synapse
104997112 (CACNA1D)
04726 Serotonergic synapse
104997112 (CACNA1D)
04723 Retrograde endocannabinoid signaling
104997112 (CACNA1D)
09159 Environmental adaptation
04713 Circadian entrainment
104997112 (CACNA1D)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
104997112 (CACNA1D)
09164 Neurodegenerative disease
05010 Alzheimer disease
104997112 (CACNA1D)
05020 Prion disease
104997112 (CACNA1D)
05022 Pathways of neurodegeneration - multiple diseases
104997112 (CACNA1D)
09165 Substance dependence
05031 Amphetamine addiction
104997112 (CACNA1D)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
104997112 (CACNA1D)
05412 Arrhythmogenic right ventricular cardiomyopathy
104997112 (CACNA1D)
05414 Dilated cardiomyopathy
104997112 (CACNA1D)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
104997112 (CACNA1D)
04934 Cushing syndrome
104997112 (CACNA1D)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
bbis04040
]
104997112 (CACNA1D)
Ion channels [BR:
bbis04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
104997112 (CACNA1D)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ion_trans
CAC1F_C
Ca_chan_IQ
GPHH
PKD_channel
NCAPD3_N
Motif
Other DBs
NCBI-GeneID:
104997112
NCBI-ProteinID:
XP_010849980
Ensembl:
ENSBBBG00000004432
UniProt:
A0A6P3IGG9
LinkDB
All DBs
Position
Unknown
AA seq
2139 aa
AA seq
DB search
MMMMMMMKKMQHQRQQQADHANEANYARGTRLPLSGEGPTSQPNSSKQTVLSWQAAIDAA
RQAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLSLNNPIRRACI
SIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKI
IAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGKSGGFDVKALR
AFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKT
CFFADSDMVAEEDPAPCAFSGNGRQCTANGTECRSGWGGPQGGXTNFDNFAFAMLTVFQC
ITMEGWTDVLYWMNDAMGFELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARG
DFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEESKRNTSMPTSETESVNTENVS
GEGENRGCCGSLCQAISKSKLSRRWRRWNRFSRRRCRAAVKSVTFYWLVIVLVFLNTLTI
SSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGIT
ETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLVASLLNSMKSIASLLLLLFLF
IIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQILTGEDWNAVMYDGIMAYGG
PSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNTAQKEEAEEKERKKIARK
ESLENKKNNKPEVNQIANSDNKVTIDDYREEDEDKDPYPPCDVPVGEEEEEEEEDEPEVP
AGPRPRRISELNMKEKIAPIPEGSAFFILSKTNPIRVGCHKLINHHIFTNLILVFIMLSS
AALAAEDPIRSHSFRNTILGYFDYAFTAIFTVEILLKMMTFGAFLHKGAFCRNYFNLLDM
LVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMI
VTTLLQFMFACIGVQLFKGKFYRCTDEAKSNPEECRGLFILYKDGDVDSPVVRERIWQNS
DFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENVGPIYNYRVEISIFFIIYIIIVA
FFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWY
VVNSSPFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDILNMVFTGVFTVEMVLKVIAFK
PKGYFSDAWNTFDSLIVIGSIVDVALSEADNSEESNRISITFFRLFRVMRLVKLLSRGEG
IRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQMFGKVAMRDNNQINRNNNFQTFPQA
VLLLFRCATGEAWQEIMLACLPGKQCDPDSDYNPGEEYTCGSNFAIVYFISFYMLCAFLI
INLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPP
LGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGNLEQANEELRA
VIKKIWKKTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKN
STIALQAGLRTLHDIGPEIRRAISCDLQDDDPEETKREDEEDVFKRNGALLGNHVNHVNS
DRRDSLQQTNTTHRPLHVQRPSIPPASDTEKPLFPPAGNSVCHNHHNHNSIGKQVPSSTN
ANLNNANMCKAAPGKRPSIGNLELVSENGHHSFHKHGREPHRRCSIKRSDSGDEQFPTIC
REDPEIHGYFRDPHCPGEQEYFSSEEYYEDDSSPTGSRQSYGCGYYNWYLGSSLDFERPR
GYHHPQSFSEDDDSPVGYDSRRSPRRRLLPPTPTSPRRSSFNFECLRRQSSQEEVPPSPA
FPPRTALPLHLMQQQIMAVAGLDSSKAQKYSPSHSTRSWATPPATPSYRDWTPCYTPLIQ
VERPEAPDQVNGSLPSLHRSSWYTDEPSVSYRTFTPASLTVPSSFHNKNSDKQRSADSLV
EAVLISEGLGRYARDPKFVSATKHEIADACDLTIDEMESAASNLLNGNVHPRANGDVGPV
SHRQDYELQDFGPGYSDEEPDPGRDEEDLADEMICITTL
NT seq
6420 nt
NT seq
+upstream
nt +downstream
nt
atgatgatgatgatgatgatgaaaaaaatgcagcatcaacggcagcagcaagcggaccac
gcgaacgaggcaaactatgcaagaggcaccaggctccctctttctggtgaaggaccaact
tctcagccgaatagctccaagcaaaccgtcctgtcttggcaagctgcaatcgacgctgct
agacaggccaaggctgcccaaactatgagcacctccgcacccccacctgtcggatctctc
tcccaaagaaaacgtcagcaatacgccaagagcaaaaaacagggtaactcgtccaacagc
cgacctgcccgtgcccttttctgtttgtctctcaataaccccatccgaagagcctgcatt
agtatagtggaatggaaaccatttgacatatttatattattggctatttttgccaattgt
gtggccttagctatttacatcccattccctgaagatgattctaattcaacaaatcataac
ttggaaaaagtagaatatgccttcctgattatttttacagtcgaaacatttttgaagatt
atagcatatggattattgctacatcctaatgcttatgttaggaatggatggaatttactg
gattttgttatagtcatagtaggattgtttagtgtaattttggaacaattaaccaaagaa
acagaaggcggtaaccactccagtggcaaatcaggaggctttgacgtcaaagccctccgc
gcctttcgagtgttacgaccacttcgactagtatcaggagtgcccagtttacaagttgtc
ctgaactccattataaaagccatggttcccctccttcacatagcccttttggtattattt
gtaatcataatctatgctattataggattggagctttttattggaaaaatgcacaaaaca
tgtttttttgctgactcagatatggtggctgaagaggacccagcgccgtgtgcgttctca
gggaacggacgccagtgcaccgccaatggcacggagtgtaggagtggctggggggggccc
caggggggnnnnaccaactttgacaactttgcctttgccatgctcaccgtgtttcagtgc
atcaccatggagggctggacagacgtgctctactggatgaatgatgctatgggatttgaa
ttgccctgggtgtattttgtcagtctcgtcatctttgggtcatttttcgtactaaatctt
gtacttggtgtattgagcggagagttctcgaaggaaagggagaaagcaaaagcacgggga
gacttccagaagctccgggagaagcagcagctggaagaggatcttaagggctacttggac
tggatcacccaagcagaagacattgatcctgagaatgaagaagaaggaggcgaggagagc
aaacgaaataccagcatgcccaccagtgagacggagtctgtgaacacagagaacgtgagc
ggggaaggcgagaaccgaggctgctgtgggagtctctgtcaagccatctcaaagtccaag
ctcagccgccgctggcgccgctggaaccgcttcagtcgcagaaggtgtagggctgctgtg
aagtccgtcacgttttactggctggtcattgtcctggtgtttctcaacaccttaaccatt
tcctccgagcactacaaccagcctgactggttgacacagattcaagatattgctaacaaa
gtcctcttggctctgttcacctgtgagatgctggtcaaaatgtacagcttgggtctccag
gcgtactttgtctctcttttcaatcggtttgattgcttcgtggtgtgcggcggaattacc
gagacgatcctggtggaactggaaatcatgtctcccctgggcatctctgtgttccgctgt
gtgcggctcttgagaattttcaaagtgaccaggcactggacctccctgagcaacttggtg
gcatccttgttaaactccatgaagtccatcgcttcgctgctgcttctgctttttctcttc
atcatcatcttctccttgctggggatgcagctgtttggcggcaagtttaattttgatgaa
acgcaaaccaagcggagcaccttcgataatttcccgcaagcccttctcacagtgttccag
atcctgacaggcgaagattggaatgctgtgatgtatgacggtatcatggcatatgggggc
ccatcatcttctggaatgatcgtctgcatctacttcatcatcctcttcatttgcggtaac
tatattctactgaatgtcttcttggccatcgctgtagacaatttggctgatgctgaaagt
ttgaatactgctcagaaggaggaagctgaagaaaaggaaaggaaaaagattgccagaaaa
gaaagtctggaaaataaaaagaacaacaaaccagaagtcaaccagatagccaacagtgac
aacaaggttaccatcgacgactacagagaagaggatgaggacaaggacccctacccaccc
tgtgatgtgccagtaggtgaagaggaagaggaggaggaagaggatgaacctgaggttcct
gctggcccccgtcctcgcagaatctctgagttgaacatgaaagagaaaatcgcccccatc
ccggaagggagtgctttcttcattctcagcaagaccaacccgatccgcgtgggctgccac
aagctcatcaaccaccacatcttcaccaacctcatcctcgtcttcatcatgctgagcagc
gccgccctcgccgctgaggaccccatccgcagccactccttccggaacactatactgggt
tactttgactatgctttcacagccatctttactgttgaaatcctgttgaagatgatgacc
tttggcgctttcctccacaaaggcgctttctgcaggaactacttcaacttactggatatg
ctggttgttggggtgtctttggtgtcatttgggatccaatccagtgccatctctgttgtg
aagattctgagggtcctaagggtcctgaggcctctcagggccatcaacagagcgaaagga
cttaagcatgtggtccagtgtgtcttcgtggccatccggacgattggcaacatcatgatc
gtcaccacgctcctccagttcatgttcgcctgcatcggggtccagctcttcaagggaaag
ttctatcgctgcacagacgaagccaaaagtaaccccgaagagtgcagggggctcttcatc
ctctacaaggatggggatgttgatagtcctgtggtccgtgagaggatctggcaaaacagt
gatttcaactttgacaacgtcctctcggctatgatggctctgttcacagtctccacgttc
gagggctggcccgcgttgctgtacaaagccatcgattcgaacggagagaatgtgggcccc
atctacaactaccgtgtggagatctccatcttcttcatcatctacatcatcattgtcgca
ttcttcatgatgaacatcttcgtgggcttcgtcatcgtcacatttcaggagcagggagag
aaagagtataagaactgtgagctggacaaaaatcagcgtcagtgtgttgaatacgccttg
aaggcacgtccgctgcggagatacatccccaaaaacccctaccagtacaagttctggtac
gtggtgaactcctcgcctttcgaatacatgatgtttgtcctcatcatgctcaacacactc
tgcttggccatgcagcactacgagcagtccaagatgtttaatgacgccatggacatcctg
aacatggtcttcactggggtgttcactgtcgagatggttttgaaagtcattgcatttaag
cctaaggggtactttagtgacgcctggaacacctttgactccctcatcgtaatcggcagc
attgtagacgtggccctcagcgaagccgacaactctgaagagagcaatagaatctccatc
acctttttccgtcttttccgagtgatgcgattggtgaagcttctcagcaggggggaaggc
atccggacgctgctgtggacttttattaagtccttccaggcgctcccgtatgtcgccctt
ctcattgccatgctgttcttcatctacgcggtcatcggcatgcagatgttcgggaaagtg
gccatgagagataacaaccagatcaacagaaacaacaatttccagacctttccccaggcg
gtgctgctgctcttcaggtgtgcgacgggggaggcctggcaggaaatcatgttagcctgc
ctcccggggaagcaatgcgaccccgactcggattacaaccctggggaggaatacacatgt
gggagcaacttcgccatcgtttatttcatcagtttttatatgctctgcgcatttctgatc
atcaacctcttcgtggctgtcatcatggacaattttgattatctcacccgggactggtct
attctggggcctcaccatttagatgaattcaaacggatctggtctgaatatgaccctgag
gcaaagggcaggatcaagcacctggacgtggtcactctgctccgccgcatccagcctccc
ctgggcttcgggaagttgtgtccacaccgggtagcctgcaagagactagttgctatgaac
atgccactcaacagtgatgggacagtcatgtttaatgcaactctgtttgctctggttcga
acggctcttaaaatcaagactgaaggcaacctggaacaagctaatgaagaactccgagct
gtgatcaagaaaatttggaagaaaaccagcatgaagctacttgaccaagttgttcctcca
gctggtgatgatgaggtaaccgtggggaagttctatgccactttcctgatacaggactac
tttaggaaattcaagaaacggaaagaacaaggactggtgggaaaataccccgcgaagaac
agcacaattgccctacaggcgggattaaggacactgcatgacattgggccagaaatccgg
cgtgctatatcatgcgatttgcaagatgatgatccagaggaaacaaaacgagaagatgaa
gaagatgtgttcaaaagaaatggtgccctgcttggaaaccatgtcaatcatgttaatagt
gataggagagattcccttcagcagaccaataccacccaccgtcccctgcatgtccaaagg
ccttcaattccacctgcaagtgatactgagaaaccgctgtttcctccagcaggaaattcg
gtgtgtcataaccatcataaccataattccataggaaagcaagttcccagctcaacaaat
gccaatctcaataatgccaatatgtgcaaagctgcccctggaaagcggcccagcattggg
aaccttgagcttgtgtctgaaaacgggcatcattccttccacaagcatggccgtgagcct
cacagaaggtgcagtattaaaaggtctgactcaggagacgagcagttcccgacgatttgc
cgggaggacccggagatacacggctacttcagggacccccactgcccaggggagcaggag
tatttcagcagcgaggagtactatgaggatgacagctcgcccaccgggagcaggcaaagc
tacggctgcggctactataactggtacctgggcagcagcttggactttgagcggcctcga
ggctaccatcacccccaaagcttctcagaggacgacgactcgcccgttggctacgattcc
cggaggtctccgaggcgacgcctactacctcccacccctacatccccccgcaggtcttcc
ttcaacttcgagtgcctgcgccggcagagcagccaggaggaggtcccgccgtcgcccgcc
ttcccgccccgcacggccctgcccctgcacctgatgcagcagcagatcatggcagtcgcc
ggcctagattccagtaaagcccagaagtactcgccaagccactccacccggtcgtgggcc
acgcccccggccacgccgtcgtatcgggactggacaccgtgttataccccgctgatccag
gttgagcggccagaggccccagaccaggtcaacggcagcctcccgtccctgcaccgcagc
tcgtggtacacggacgagcccagcgtctcctatcggacgttcacaccagccagcctgacc
gtccccagcagcttccacaacaagaacagcgacaagcagaggagcgcggacagcctggtg
gaggcagttctgatatccgaaggcttaggacggtacgcgagggacccaaagttcgtgtcg
gcgacaaaacacgaaatcgccgatgcctgtgacttaaccatcgacgagatggagagtgcg
gccagcaacctgctaaacgggaacgtgcatccccgggccaatggagacgtgggccccgtt
tcccaccggcaagactacgagctccaggactttgggcctggctacagcgacgaggagccg
gaccccgggagggacgaggaggacctggcagacgagatgatttgcatcaccaccctgtag
DBGET
integrated database retrieval system
