Bison bison bison (American bison): 104998054 Help Entry 104998054         CDS       T08726                                  Symbol PLA2G4A Name (RefSeq) cytosolic phospholipase A2   KO K16342   cytosolic phospholipase A2 [EC:3.1.1.4] Organism bbis  Bison bison bison (American bison) Pathway bbis00564   Glycerophospholipid metabolism bbis00565   Ether lipid metabolism bbis00590   Arachidonic acid metabolism bbis00591   Linoleic acid metabolism bbis00592   alpha-Linolenic acid metabolism bbis01100   Metabolic pathways bbis04010   MAPK signaling pathway bbis04014   Ras signaling pathway bbis04072   Phospholipase D signaling pathway bbis04217   Necroptosis bbis04270   Vascular smooth muscle contraction bbis04370   VEGF signaling pathway bbis04611   Platelet activation bbis04664   Fc epsilon RI signaling pathway bbis04666   Fc gamma R-mediated phagocytosis bbis04724   Glutamatergic synapse bbis04726   Serotonergic synapse bbis04730   Long-term depression bbis04750   Inflammatory mediator regulation of TRP channels bbis04912   GnRH signaling pathway bbis04913   Ovarian steroidogenesis bbis04921   Oxytocin signaling pathway bbis05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:bbis00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     104998054 (PLA2G4A)    00565 Ether lipid metabolism     104998054 (PLA2G4A)    00590 Arachidonic acid metabolism     104998054 (PLA2G4A)    00591 Linoleic acid metabolism     104998054 (PLA2G4A)    00592 alpha-Linolenic acid metabolism     104998054 (PLA2G4A)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     104998054 (PLA2G4A)    04014 Ras signaling pathway     104998054 (PLA2G4A)    04370 VEGF signaling pathway     104998054 (PLA2G4A)    04072 Phospholipase D signaling pathway     104998054 (PLA2G4A)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     104998054 (PLA2G4A)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     104998054 (PLA2G4A)    04664 Fc epsilon RI signaling pathway     104998054 (PLA2G4A)    04666 Fc gamma R-mediated phagocytosis     104998054 (PLA2G4A)   09152 Endocrine system    04912 GnRH signaling pathway     104998054 (PLA2G4A)    04913 Ovarian steroidogenesis     104998054 (PLA2G4A)    04921 Oxytocin signaling pathway     104998054 (PLA2G4A)   09153 Circulatory system    04270 Vascular smooth muscle contraction     104998054 (PLA2G4A)   09156 Nervous system    04724 Glutamatergic synapse     104998054 (PLA2G4A)    04726 Serotonergic synapse     104998054 (PLA2G4A)    04730 Long-term depression     104998054 (PLA2G4A)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     104998054 (PLA2G4A)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     104998054 (PLA2G4A) Enzymes [BR:bbis01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.1  Carboxylic-ester hydrolases     3.1.1.4  phospholipase A2      104998054 (PLA2G4A) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PLA2_B C2 cPLA2_C2 Motif Other DBs NCBI-GeneID:  104998054 NCBI-ProteinID:  XP_010851366 Ensembl:  ENSBBBG00000023675 UniProt:  A0A6P3I9Z3 LinkDB All DBs Position Unknown AA seq 749 aa AA seqDB search MSFIDPYQHIIVEHHYSHKFTVVVLRATKVTKGTFGDMLDTPDPYVELFISSTPDSRKRT RHFNNDINPVWNETFEFILDPNQENILEITLMDANYVMDETLGTTTFPISSMKVGEKKQV PFIFNQVTEMILEMSLEVCSSPDLRFSMALCDQEKAFRQQRKENIKENMKKLLGPKNSEG LHSTRDVPVVAILGSGGGFRAMVGFSGVMKALYESGILDCATYIAGLSGSTWYMSTLYSH PDFPEKGPEEINKELMKNVSHNPLLLLTPQKIKRYVESLWRKKSSGQPVTFTDIFGMLIG ETLIHNRMNTTLSSLKEKVNTGQCPLPLFTCLHVKPDVSELMFADWVEFSPFEIGMAKYG TFMAPDLFGSKFFMGTVVKKYEENPLHFLMGVWGSAFSILFNRVLGVSGSQSKGSTMEEE LENITAKHIVSNDSSDSDDESQGPKGTENEEAEREYQNDNQASWVQRMLMALVSDSALFN TREGRAGKVHNFMLGLNLNTSYPMSPLRDFTMQESLDEDELDAAVADPDEFEQIYEPLDV KSKKIHVVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDSSPPFKELLLAEKWAKMN KLPFPKIDPYVFDREGLKECYVFKPKNPDVEKDCPTIIHFVLANINFRKYKAPGVPRETN EEKEIADFDIFDDPESPFSTFNFQYPNQAFKRLHDLMYFNTLNNIDIIKNAIVESIEYRR QNPSRCSVSLSSVEARRFFNKEFLSKPTA NT seq 2250 nt NT seq  +upstreamnt  +downstreamnt atgtcatttatagatccttatcaacacattatagtggagcaccattattcccacaagttc acagtagtggtgctgcgtgccacaaaagtgacaaagggaacctttggtgacatgcttgac actccagacccctatgtggaacttttcatctcttcaacccccgacagcaggaagagaaca agacacttcaataatgacataaaccctgtgtggaatgagacctttgaatttattttggat cctaatcaggaaaatattttggagatcactttaatggatgccaattatgttatggatgaa actcttgggacgacaacgtttcccatatcttctatgaaagtgggagagaagaaacaggtt ccttttattttcaatcaagtcactgaaatgattctggaaatgtctcttgaagtttgttca tccccagacctccggtttagtatggctctgtgtgaccaggagaaagctttcagacaacag agaaaggaaaacataaaggaaaacatgaagaaactgctgggtccaaagaatagtgaaggc ttgcattctacacgtgatgtgcctgtggtggccatactgggctcaggtgggggatttcga gccatggtaggattctctggtgtgatgaaggcactgtatgagtcagggattttggactgt gctacctacattgctggtctttctggatccacatggtatatgtcgaccttatattctcac ccagattttccagagaaagggccagaggagattaacaaagagctaatgaaaaatgtcagc cacaaccctcttttacttctcacaccacagaaaattaaaagatatgttgagtctttatgg aggaaaaaaagttctggacaacctgtcacctttactgatatcttcgggatgttaatagga gaaacactaattcacaatagaatgaacactaccctgagtagtttgaaggaaaaagtcaat actgggcagtgtcctctgccgcttttcacctgtctccatgtcaaacccgatgtctcagag ctgatgtttgcagattgggttgaatttagtccatttgagattggcatggctaaatatggt acttttatggcgcctgacttatttggaagcaaattttttatgggaacagttgtaaagaaa tacgaagaaaaccccttgcatttcttaatgggtgtctggggtagtgccttttctatattg ttcaacagagtcttgggagtttctggatcacaaagtaaaggttccacaatggaagaagaa ctagaaaatattacagcaaagcatattgtgagtaatgatagctcagacagtgatgacgaa tcacaaggacccaaaggcactgaaaatgaagaagcagaaagggaataccaaaatgataat caagcaagttgggtccaacgtatgctcatggccttggtgagtgactcagctttgttcaat accagagaaggacgtgccgggaaggtgcacaactttatgctgggcttgaatctcaataca tcctatccaatgtctcctttgagagactttaccatgcaagagtccctggatgaagacgaa ttggatgccgctgtcgcagatcctgatgaatttgagcagatatatgagcctttggatgtc aaaagtaaaaagattcatgtggtggacagtggcctcacatttaaccttccataccctttg atcctgagacctcagaggggagttgatctcatcatctcctttgacttttctgcaagacca agtgactccagtcctccgttcaaggaacttctacttgcagaaaagtgggctaaaatgaac aagctcccctttccaaagattgatccttacgtgttcgatcgagaaggactgaaagaatgc tatgtttttaaacccaagaatcctgatgtcgagaaagattgcccgactatcattcacttt gttctggccaacatcaacttcagaaagtacaaggctccaggtgttccaagagaaactaat gaagagaaagaaatagctgattttgatatttttgatgaccctgaatcaccgttttcgacc ttcaactttcaatatcccaatcaagcatttaaaaggctgcatgatctcatgtacttcaat accctgaacaacattgatataataaagaatgctatagtcgaaagcatcgaatatagaagg cagaatccgtctcgttgctctgtttccctcagtagtgttgaggcaagaagattcttcaac aaggagtttctaagcaaacccacagcatag

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