Bison bison bison (American bison): 104998214 Help Entry 104998214         CDS       T08726                                  Symbol USH2A Name (RefSeq) usherin   KO K19636   usherin Organism bbis  Bison bison bison (American bison) Brite KEGG Orthology (KO) [BR:bbis00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    03037 Cilium and associated proteins [BR:bbis03037]     104998214 (USH2A) Cilium and associated proteins [BR:bbis03037]  Primary cilia and associated proteins   USH complex and associated proteins    104998214 (USH2A) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  fn3 EGF_laminin Pur_ac_phosph_N Ig_DSCAM-DSCAML_C Laminin_G_2 Laminin_G_1 Laminin_N Laminin_G_3 EGF_LMN_ATRN Fn3_VIN3 Motif Other DBs NCBI-GeneID:  104998214 NCBI-ProteinID:  XP_010851596 Ensembl:  ENSBBBG00000018368 UniProt:  A0A6P3IAL9 LinkDB All DBs Position Unknown AA seq 5204 aa AA seqDB search MNCLALSLGFGLLFPVPETWLFAYFASISWADSQGLFPRLENVAAFKKVSVVPTQATCGI PAQSTFCQSSATPEGLRVCPQRLCVQDCPYRSSPPTYSNLFSAGLRGCIIKDQRDLSPNS HNHSASFIFGNHQSCFASPPAPRLAASFTLAVWLKLEQGGVMCVIEKTADGQIVFKLTIS EKETMFYYRTVNGLQPPIKVMTLGRILVKKWIHLSVQVHQTKISFFINGLEKDNAAFDAR TLSGSITDFASGTMQIGQSLNGSEQFVGRMQDFRLYQVALTNREIQEVFSRDLPRLHIQS HCRCPGSHPRVHRLEQRYCIPNDAEDTTKNRVLRLNPEAHPLSFVNDNNVGTSWVSRVFT NMTQLSQGVTISIDLENGQYQVFYIIIQFSSPQPTAVRIQRKKEDSLDWEDWQYFARNCS TFRMKNNGDLANSDSVNCLQLPNFPPYSCGNVTFSILTPGPNQRPGYNNFYNTPSLQEFV KATQVRLHFHGQYHTTETPVSPRHRYYGVNEITITGRCQCYGHANHCDTTSQPYRCLCSQ ESFTEGLHCDRCLPLYNNKPFRQSDHVHAFNCKPCECNSHSRSCHYNISVDPFPFEHYRG GGGVCDDCEHNTAGKNCELCKDYFFRQVGADPSAIDVCRPCDCDKVGTRNSSFLCDQIGG QCNCKRHVSGRQCNQCQNGFYNLQEWDPDGCSPCNCNTSGTVDGDITCHPNSGQCKCKAN VIGLRCDHCNFGFKFLQSFNDDGCEPCQCNLHGSVNRLCNPLSGQCECKKEAKGLQCDTC REHFYGLDATGCKACDCDVAGSRPGTVCDAWTGQCVCKPNVGGRRCSECVEGYFYQPQNR SFLCLPCNCDRTGTVNGSLLCDKSTGQCPCKLGVTGLHCNQCESHRYHLTVGSFQGCQMC ECDPLGTLPGTICDPLSGQCPCLPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVN HICNSLTGQCVCQDASIAGQSCDYCKDLYFGFDSLTGRCQPCNCHLSGALNETCHLVTGQ CFCKRFVTGSKCDTCVPNASHLDISNPLGCSKTPSQQPPPRGQVQSSSAINLSWSPPDSP NAHRLTYSLFRDDFEIYTVEDQYPYNIQYFLDTALVPYTSYSYYIWTSSVHGSTRSTAVT YRTKPGTPVGSLNLSYISPVSSDSVTLTWASPSNRSGPIEKYILSCAPLHDVQPCSPYEG PETTTTIWNLLPFTKYRFAVQACTSGGCLHSTPLTVTTAQAAPRRLGPPKVRKISSTELH VEWAPPMEPNGIIIRYELYMKRLKSSGETRSAESQVFQSSGWLGPHPLAESANENALEPP ETTTVITGLEPYTKYKFRVLAVNMAGSVSSAWTTGRTGESAPVFVMPPSVSPLSPHSLNV SWELPPDSVTRGKVVGYNISMISEQSPQRSYPVVVPQVLYTAKSQELSYIVKGLKPYRIY NFTISLCNSVGCVTSASEAGQTLASAPAQLRPPLVEGINSTTMHLRWLAPEEQNGPSPVY QLERREPSLPAPRAMVMKGTRFTGHGYYKFPSSTHPVNTDFTGIKASFRTRVPEGLIVFA ASPGNQEEYFAIQLKNGRPYFLFDPQGSAVEVTTTNDDGKQYSDGKWHEIIAIRHQGLGQ ITLDGLFTGSSATTNGGTVIGENTGVFVGGLPQGYTILRKDSDIVQKGFVGCLKDVYFMK NYNPSATWEHLVWQSSEEQTNVHNDWEGCPTSLQEGAQFLGTGFLELYPYLFHGGMDFEI SFKFRTDQLNGLLLFIYNKDGPDFLAMELKSGILSFRLNTSLTFTQVDLWPGLSYCDGKW NKVIIKKNDSIISASMNELMEHVSESRAQALMVNSPVYVGGIPQELHDPYKHLKLEQGFG GCMKDVKFARGAVINLASVSSGAVRVNLDGCLSTDSAAKCRGDDSILVYRGEERTAYESH LQPFTEYLYRVTASHEGGSVHSDWSRGRTTGAAPQSVPSPSGVRSINGYSIEVTWDEPVV ARGVIEKYILRAYSEDALGPPHTPSASSELVDTNTFTGILTGLLPFKNYAVTLAACTLAG CTESLHALNISTPQEAPQQVQPPVAKSLPHSLLLSWNPPQKANGIITQYSLYMDGMLIYS GNGENYTVTDLAAFTPHQFLLSACTHVGCTNSSLVILSTTQLPPEHVDPPILTVLDSRTV YIQWKQPRKVNGILERYMLYISNHTHDFTVWDVIYNSTELFQDHTLQYLLPGNKYLIKLA ACTGGGCTVSKASQALTEERTPEGVPAPRVNPDSSHSFNISWTEPEHPNGVITSYGLYLD GILIHNSSELSCHASGFAPWSLHSFRVQACTARGCALGPLVENRTLEAPPEGTVNVFVKT EGSRKAHVRWEPPFHPNGRLMYSVLFTGTFYADQAGDNYTLLNGTQIMHSGEETNLWVLI NGLVPFTNYTVQVNVSNSQGSLMSDPVMISMPPGAPDGVLPPRLSSATPTSLQVVWSTPA RNNAPGSPRYQLQMRPGHSTHGFLELFSNPSASLNYEVRDLQPYTEYEFRLVASNGFGSA HSSWIPFITAEDKPGPVDPPIILDKKSRMMLVTWQHPLKCNGLITHYNIYQHGRLSLETS GNVTNGTVTHLHPHTAYTFQVEACTSKGCSLSADSQTVWTLPDAPEGILSPELFSDTPTS VIISWQPPTHPNGLLENSTIQRRVQGKEAVTTLVTLPGSHPRRFIDKTSSLSPWTKYEYR VLMSTAGGGTNSSDWAEVTTRPSRPAGVQPPEVDVLGPDAAKVTWKPPLILNGDILNYEI RMPDPHITITNVTSSVLSHVVTHLIPFTNYSVTIVACSGGNGYLGGCTESFPTHVTTPPA LPQDLGPLSVVPLSESYVGISWQPPSRPNGPDLRYELLRCKIQQPLASNPPEDLNMWHNI YSGTQRFYEDKGLSRFTTYAYKVFVHNSVGFTPSQEATVKTLAGRPERGANVTVTVLNHT AIDVRWVKPTFQDLQGDVEYYTLFWSSATSNESRKILPDVHSHVIGHLNPNTEYRIFISV FNGVASINSEVLHATTCDGEPQGMLPPEVVIINSTAVRVIWTAPSNPNGVVTEYSVYVNN QLYKTGINVPGSIILRELSPFTVYDIQVEVCTKYACVKSNRTQITTVEDTPSDIPTPTIH GIASRSLQIKWMSPGRPSGIILGYDLLRKTWRPCSKTKKLMKDHPGGLCKAVECQKHELL CGTRCYSPEAKVCCNGSLYDPQPGHACCEEKYIAFVLNSTGVCCGGRIRETQPNHQCCSG YYVRILPGEVCCPDEQHNRVSAGLGNSCCGRMPYSTSGKQICCAGRLHDGHGQQCCGGQI VSKDFECCGGEEEGVVYSRLPGMFCCGLDYVNMSDTICCSASSGESKAHVKKNDPVPVKC CETELIPKSQECCNGVGYNPLKYVCSDKISTGMMMKETKACRTLCPTSMEATAHCGRCDF NFTSHVCTVMRGSHSSVRKESMEEICSSAEETVHTGSVNTLSFTDVNLEPYMMYEYRISA WNRYERGFSKAVRARTKEDVPEGVSPPRWTKMDHLDDVIVLSWKKPIQSNGPIIAYILLR NGIECFRGTSLSFSDTEGIQPFMEYSYQLKACTVAGCATSSKVVAATTQGIPQNIPPPRV TAPSAEALHVSWHVPPKPNGVIKEYQLRQVGKGLIYTDTTDRRQHTVTGLQPYTNYSFTL RACTSAGCTSSEPFLGQTLQAAPQGVWVTPRHIVVNSTTVELFWSPPEKPNGLISQYQLS RNGSLIFLGGSEEQNFTDKNLEPNSRYVYKLEATTGGGSSPSDEYIIQTPILTPEEIQPP YNITVIGPYSIFVAWTPPGILVPKMPVEYNVLLNAGSATPLISSVGHHQSILLENLAPFT QYEIRIQACQKGGCGVSSRMFAKTAEAAPMDLNSPILKALGSACIEVKWMPPKKPNGVII NYFIHRRPTGIEEESLVFVWSEGALEFIDDADTLRPFTLYEYRVRACNSRGSVESPWSSA RTLEAPPQDFPAPWAQVTGAHSVLLNWTEPDSPNGIIFQYRVVYQQKTDDPTLNFSAVHA FTVMGTSYQAHLFGLEPFTTYHVGVVATNQAGEVSSPWTLVQTLESSPSGLSNFTVEQKE NGRALLLQWSEPARTNGVIKTYNVFSEDILEYTGLNRQFLFRRLDPFTLYTLTLEACTRA GCAHSAPQPLWTEEAAPDSQPAPTIQSVGSTSVELSWSEPIKPNGKIIRYEVIRRCFEGK AWGNQTIQADEKIVFIESNTERNTFIYNDTGLQPWMQCEYKVHTWNSAGHACSSWSGVRT RQAPPDGLCPPEVAQVSVNPPKVLIAWVPPEQPNGIIQSYRLQRNGMLYPFSFDAVTFNY TDEKLLPFSTYSYGVTACTSGGCSASTTTSITTLEAAPAGVHPPALRTISATQINVSWSP PSIQNGEITQYLLRLDGKEYLAGQNLTLLVSHLQPYTQYNFSLVACTKGGCTASMPESAW TMEAPPQNMDPPKLQVTGSESIEITWKLPRIPNGRIRSYELRRDGTIVYTGLETRYHDFT LTPGVEYGYTVMANNSQGGVLSPLVKDRTSPSAPSGMEPPRLLAKGPQEIFVTWDPPVRT NGRIVNYTLFIRDLFERETKIVHINTTHNSFGPQSFMVNQLKPFHRYEVRIQACTRLGCV SSDWTSIETLEVAPQQQPPPHLEVQMAPGGFQPTVSLLWTGPLQPNGKVLYYELYRRQIA TQPEKSKPVLAYNGSSSSFMDVELLPFTEYEYQVWAVNSAGKAPSSWTRCRTGPAPPEGL KAPKFHAVSATQAVVNISAPQKPNGIVTLYRLFSRSTSGAQTVLAEGLATQQTLHSLQPF TTYSIGVEACTCFSCCSQGPTAELRTPPAPPAGLSSPQIQMLASRTASFQWSPPLSPNGV IQSYELQLYKACPPDSATPCTPRQTETKYKGPGQRASLEGLQPYTTYKLRVVAHNEVGST ATEWISFVTQKELPQYRAPFSVDSNLSVVCVNWSNSFLLNGRLKEFVLTDGGQRLYSGLD TTLYIPRTADKTFFFQVICITEEGSAKTPLIQYDTSTGFGLVLTTPGEKKGSRSKSTEFY SELWFIVLMAVLGLILLAIFLSLILQRKIHKEPYIRERPPLVPLPKRRSPLNVYPPGETH VGLADTKIPRSGTPVSIRSNRSLSVLHIPSQSHGSQTYSQGSLHRSVSQLMDIQDKKVLI DDSLWETIMGHDSGLYVDEEDLMNAIKGFSSVTKEHTTFTDTHL NT seq 15615 nt NT seq  +upstreamnt  +downstreamnt atgaattgcctggctctttctctgggcttcggcctcttgtttccggtccctgaaacatgg ctctttgcctactttgcttccatctcatgggctgactctcagggcttgttcccaaggctg gagaacgtggcagccttcaagaaggtttcggtggtgccaacccaagccacgtgcggaatc ccagcccaaagcactttctgtcagagctctgccacacccgagggccttcgggtctgtcct cagaggctgtgtgttcaggattgcccttaccgatcatcgccccccacctacagcaacctc ttctcagcaggcctcaggggttgcatcattaaagaccagcgtgacctgagtcccaactcc cataaccattctgcaagtttcatttttggaaatcaccagagttgctttgcctctcctcct gctcccaggctggcggcatcatttactctagctgtgtggttgaaacttgagcaaggaggt gtaatgtgtgttatagaaaaaacagcggatgggcagattgtattcaaacttacaatatct gagaaagagaccatgttttattaccgcacagtaaatggtttgcagcctccaataaaagta atgacactggggagaattcttgtgaagaaatggattcatcttagtgtgcaggtacaccag acaaaaatcagtttcttcatcaatggtttggaaaaggataatgcagcttttgatgcaaga actctaagtggttcaattacagattttgcctctggtaccatgcaaataggacagagctta aatggttcagagcagtttgttggaagaatgcaagattttcgattataccaagtggcgctt acaaacagagagattcaggaagttttctccagagatctacccagattgcatatccagtca cattgccgttgccctggcagccaccctcgtgtccatcgtttggaacagcggtactgcatt cctaatgacgcagaagacacaaccaaaaacagggtgttacggctgaatcctgaagcccat cctctttcttttgtcaatgataacaacgttggtacttcgtgggtgtcacgtgtgtttaca aacatgacccagcttagtcaaggagtgaccatttccatagatttggaaaatggacagtat caggtgttttatattatcattcagttctctagtccacaaccaacagcagtaaggattcag aggaaaaaggaggacagcctagattgggaggattggcaatattttgctagaaattgcagc actttcagaatgaaaaacaatggagatttggcaaattctgattctgtcaactgtcttcaa cttcccaattttcctccatattcctgtgggaatgtcacgtttagcatcctaacacctgga ccaaatcagcgtcctggatacaataatttctataataccccatcacttcaagagttcgtt aaggccacccaagtacgacttcatttccatgggcagtaccatacgactgagactcctgtc agccccagacacagatactatggggtcaatgaaatcaccatcactggaagatgtcagtgc tatggtcatgccaatcactgtgacacaacaagccagccctatagatgcctctgctctcag gaaagtttcactgaaggacttcattgtgatcgctgcctgcctctttataataacaagcct ttccgccaaagtgatcatgttcatgcctttaactgtaaaccctgtgagtgcaacagccat tccagaagctgccactacaacatctcagtggatccctttccatttgagcactacagaggg ggtggaggagtttgtgatgactgtgagcataacaccgcaggaaagaactgtgagctgtgt aaggattactttttccgacaagttggtgcagatccttcagccatagatgtttgcagaccc tgtgattgtgataaagttggcacaagaaacagtagcttcctttgtgatcagatcggaggc cagtgtaattgtaagagacatgtgtctggcagacagtgcaatcagtgccagaacggattc tacaacctccaggagtgggatcctgatggctgcagtccgtgcaactgtaatacctctggg acagtggatggagatattacctgtcacccaaattcaggccagtgcaagtgcaaagcaaat gttattgggctcagatgtgatcactgcaattttgggtttaaatttctccaaagttttaat gacgatggatgtgagccctgccagtgtaacctccacggctcagtgaacagactctgcaat cctctttctgggcagtgtgagtgcaaaaaggaagccaaaggacttcaatgtgacacctgc agagaacacttttacggactggacgccaccggttgtaaggcctgtgactgtgatgtggcg gggtcccggcctgggacggtctgtgatgcttggacaggacagtgcgtctgcaagcccaac gttgggggaagacgctgcagtgagtgtgtggaggggtacttctaccagccgcaaaaccgt tctttcctctgcctgccttgtaactgtgataggactgggaccgtaaatggctctctgctc tgtgacaaatcgacaggacagtgtccctgcaaattaggagtaacaggtcttcactgcaat cagtgtgagtctcacaggtaccatctgaccgttggcagttttcagggctgccagatgtgt gagtgtgatcccctggggacattacctgggaccatttgtgacccactcagtggccagtgc ccatgtttgcctaaccgtcaaggaagaaggtgtaatcagtgtcaaccaggcttttatatt tctccaggcaatgccactggctgcctgccatgttcatgccacaccactggtgcagttaat cacatctgtaatagcttgactggtcagtgtgtttgccaagatgcttccattgctggacaa agttgtgactattgtaaagatctttactttggatttgattctctaactgggagatgtcag ccttgcaattgtcatctctcgggagccttaaatgaaacctgtcacttggtcacaggccag tgtttctgtaaacgatttgttactggatcaaagtgtgatacctgtgttcccaatgcaagc catttggatatcagcaacccgttgggctgtagcaaaactccatcccagcaacctccaccc agaggacaagttcaaagttcttctgctatcaatctttcctggagtccacctgattctcca aatgcccaccggcttacttacagtttattcagggacgatttcgaaatctacacagttgaa gatcaatacccatataatattcagtacttcttagacactgccctggtgccatatacctcg tattcctattatatctggaccagcagcgtgcatggttcaacacgaagcacagctgtcacc tacaggacaaaaccagggaccccagtgggaagtttgaatttaagttatattagccctgtt agctcagactctgtgacacttacctgggcttcaccttcaaatcgttctggtcctattgag aagtatattttgtcctgtgctcctcttcatgatgtccagccctgttctccctatgaaggc cctgagaccaccactaccatctggaatctgcttccattcaccaagtaccgttttgctgtg caggcgtgtactagtgggggctgtttgcacagcacccctttgacagtgaccaccgcccag gcagctcccagaaggctgggtccacccaaggtgcggaagatcagttccacagagcttcac gtagaatgggctccaccgatggaaccaaatggcataattataagatatgaactgtatatg aaaagactgaagtctagtggagaaacaaggtcagcagaaagtcaagtttttcagagcagt ggctggctcggtcctcaccctcttgcagaatcagccaatgaaaatgctctagaacctcca gaaacaaccacagtcatcactggcttggagccatacaccaagtacaagtttagagtctta gctgtgaacatggctgggagtgtgtcttctgcctggaccacaggaagaacgggagaatca gcgcctgtatttgtgatgcccccttcagtctccccactgtctcctcactcgctcaatgtg tcctgggagctgccaccggacagtgttacaagaggaaaagttgtggggtataacatcagt atgatttctgaacaatcaccccaacgatcttatccagtggtggttccacaggtattgtat actgctaaatcccaagaactatcttatattgtaaaaggactaaaaccttataggatatac aactttactatttctctctgcaactcagttggctgtgtaaccagtgcttcagaagcagga cagactttagcatcagcaccagcccaactgaggccgcctctggttgaaggaatcaacagc acaaccatgcatcttaggtggctggcacctgaagagcagaatggaccttctcctgtgtat caactggaaaggagagagccatccctaccggctccgagggccatggtgatgaaagggact cgcttcacaggacatggatattataagttccccagctccactcacccagtcaatacagac ttcacgggtattaaagccagctttcgaacaagggtgcctgaaggtttgattgtctttgcg gcatcacctggcaatcaggaagagtattttgcaattcagttgaagaatggacgcccatat tttctttttgatcctcaggggtctgcagtggaagttaccacaactaatgatgatggtaaa caatatagtgatggcaaatggcatgagataattgctattaggcatcaaggtttgggccaa atcacacttgatgggctgttcacaggctcttcagccaccacgaatggtggtactgttatt ggagagaacacaggagtgtttgtgggtgggctgccacagggttacaccattctcagaaag gattctgacatagtccaaaagggttttgtgggctgtctcaaggatgtgtatttcatgaag aattataatccctctgctacttgggagcatctggtttggcagagttctgaagagcaaacc aatgtgcataacgactgggagggatgccccacttcactccaagagggagcccagtttcta gggacagggttcctggagctttatccatacttgtttcatggtggaatggactttgaaatt tcttttaagttcagaactgaccaactgaatggattgctgcttttcatttataacaaagat ggacctgattttcttgctatggagctgaagagtggaatattgagcttccggttaaatact agtcttacttttacacaagtggatctttggccggggctgtcctactgtgatggaaagtgg aataaagtgatcattaaaaaaaatgattccatcatatcagcaagcatgaatgaactgatg gagcacgtgtcagagtccagagcccaggcgctgatggtgaattcccccgtctatgtggga ggaatcccacaggagctgcatgacccctataaacacctgaagctggaacaaggtttcggt ggttgcatgaaggatgtgaagtttgcacggggtgctgtcattaacttggcatctgtgtcc agtggtgctgtcagagtcaatctggatggatgcttgtcaactgacagtgctgctaagtgc aggggagatgactccatcctggtgtaccggggagaagagcggactgcttatgagagccat ctccagccattcacagaatacctgtatcgagtaacagcctcacatgaaggaggttcggta catagtgattggagccggggccgcacaacaggagcagctccacaaagtgtgccaagtccc tcaggagtccgcagcataaatggctatagcatcgaggtgacctgggatgaacctgttgtg gctagaggtgtaattgagaagtatatcctgagagcctacagtgaggatgctcttggtcca ccccacacaccctctgccagctctgagcttgtcgataccaacaccttcacaggcatattg acaggcttgctacccttcaaaaactatgcagtaaccctagctgcttgcactttggctggc tgtaccgagagcttgcatgcattgaacatctctactccacaagaagccccacaacaggtt cagccaccagtagccaaatcccttccccattctttgttactctcctggaatccaccccaa aaagctaatggcattataactcagtactctttatatatggatgggatgctaatctactca ggcaatggagagaactacacagtcacagatttagcagcatttacacctcaccaatttctg ctcagtgcttgcacacatgtgggatgtacaaacagctccctggtcatactgtccaccaca cagctgccaccagaacacgtggatccccccattctgactgtcctggattctagaactgta tacattcagtggaaacaaccaagaaaagtaaatggaattctggagcgctatatgttatat atttcaaatcacacacatgattttacagtttgggatgtcatctataacagcacagaactt tttcaggatcacactctgcagtaccttttacctggtaataaatatctcatcaaactggca gcttgcacggggggcgggtgcacagtgagtaaggccagccaggccctgactgaggagagg acccccgaaggcgtgccggctcccagagtgaacccagactcctctcactcctttaacatc tcctggactgagcctgagcatccgaatggtgttatcacaagttacgggctgtatctcgat ggtatattaattcacaactcctcagaactcagttgtcatgcttctggattcgctccttgg agcttgcattccttcagggtccaagcctgcacggccagaggttgtgctctgggcccactg gtggaaaatcgaactctggaagctcctcctgaaggaacagtaaatgtgtttgtcaaaaca gaaggatcccgaaaagcccacgtaaggtgggaaccaccttttcaccctaatggacgcttg atgtactcagtcctttttactggcactttctatgctgaccaagcaggtgataactacact cttctgaatggcacacaaatcatgcacagtggtgaagagaccaacctttgggtgctcatc aacggattggttccttttacgaactacacagtacaagtgaatgtttccaatagccaaggc agtttgatgagtgatcctgtaatgatttcaatgcctccaggggctccagatggcgtgctg cctccgaggctttcatctgccactccaaccagtcttcaggttgtctggtctacaccagct cggaacaacgcccccggctctcccagataccaactccagatgaggcctggccactccacc catgggtttctagagctattttccaatccttctgcatcgttaaactatgaagtgagagat ctccaaccatacacagagtatgaatttcggttggttgcctccaatggatttggcagtgcc catagctcttggattccgttcatcaccgcagaggacaaacctggacctgtagaccctcca attatcctggacaagaagtcaagaatgatgttggttacctggcagcatcctttaaagtgc aatgggctcattacccattataacatttaccaacatggccgcctcagcttggaaacttct ggaaatgtcactaatggcacagtgacccatttacacccacatacggcctatacgtttcaa gtagaagcttgtacttcaaaagggtgttccctgtcagcagattcccagactgtttggaca ctcccagatgcaccagaaggtatcctgagtccagagttgttctctgataccccaacatcc gtgatcatatcttggcaaccccccacccatcccaacggcttgctggagaactccacaatc cagagaagagtccaagggaaggaggcagttaccaccctggtgactctcccaggaagtcat cccaggaggtttattgacaagacttcttctcttagcccgtggacaaagtatgagtatcga gtgctgatgagcactgctggtggagggacaaacagcagtgattgggcagaagtgaccact agaccctcgcgacctgctggggtgcagccccccgaggtggatgtgttaggacccgatgca gccaaggtcacttggaagcccccactcatcctgaatggagacatccttaactacgagatc cgcatgcctgaccctcacatcacgatcaccaatgttacttcttctgtgttaagtcatgtc gttactcatctgattcctttcactaattactccgtcaccattgtggcttgctcagggggt aacgggtatctaggggggtgcacagagagcttccctacccatgtgaccacccctcccgcc ctgccgcaggatcttggcccattgtccgtggttccactaagtgaatcatatgttgggatt tcctggcagccaccatccaggccaaacggacctgatttgagatatgagcttctgagatgt aaaatccagcaaccacttgcatcaaatcccccagaagatttaaatatgtggcacaatatt tattcaggaactcagcggttttatgaagataagggtcttagcaggtttacgacgtatgcg tataaggtctttgtacataacagtgtgggttttacaccaagtcaagaagcgacggtgaaa acattagctgggcgtccagagagaggagccaatgtcactgtgactgttcttaaccacaca gccatagacgtgagatgggtgaaaccaacttttcaagacctacaaggtgatgttgagtat tatacacttttttggagttctgctacctccaatgaatctcgaaaaatcctcccagatgta cactctcacgtcattggccacttaaatccaaacacagagtatcggattttcatctctgtt ttcaacggagtcgccagcatcaacagtgaagtgctgcatgcaaccacttgcgatggggag cctcagggcatgcttcctccagaggttgtcatcatcaacagtacagctgtacgtgtcatc tggacagctccttcaaacccaaatggtgttgtcactgaatattccgtctatgtaaataat cagctctacaagactggaataaatgtgcctgggtctatcattctgagagagctgtctccc ttcactgtctatgacatccaggttgaagtctgcacaaaatatgcctgtgtaaaaagcaac agaacccaaatcacgactgtggaagatactccaagtgatataccgactcccacaattcat ggcatcgcttcaagatcccttcaaattaaatggatgtctccagggaggccaagtggcatc attcttggatatgatctcttacggaaaacatggcgtccgtgctctaaaactaagaagtta atgaaggaccaccctggtggactctgcaaggcagtggagtgtcaaaaacatgaacttctt tgtggaaccaggtgctactcccctgaggctaaggtttgttgtaatggatctctctatgac cctcagcctggacatgcctgttgtgaagagaagtacatagcatttgttttgaactcaact ggagtttgttgtggtggccgcatacgagagacacaaccaaatcatcagtgttgctcaggg tattatgttagaattctaccaggtgaagtatgttgtccagatgaacagcacaatcgggtt tccgctggcctaggcaactcctgctgtggcagaatgccgtactccacctcaggaaagcag atttgctgtgctgggaggctccatgatggccatggccagcagtgctgtggtggacagatt gtgagcaaagatttcgagtgctgcgggggagaggaagagggtgtggtatacagtcgcctt ccagggatgttctgttgtgggctggattatgtgaatatgtcagataccatatgctgctca gcttccagtggagagtctaaagcacatgttaaaaagaatgacccagtgccagtaaaatgc tgtgagactgaacttattccaaagagccaggaatgctgtaatggagttggatataatcct ttgaaatatgtttgctctgacaagatttcaactggaatgatgatgaaggaaacgaaagca tgccgaaccctctgcccgacgtccatggaagccacagcacactgcggcaggtgtgacttc aattttaccagccacgtttgtacggtgatgagaggatctcacagttccgtcaggaaggaa tcaatggaagaaatatgttcatctgctgaagagactgttcatacgggaagtgtaaacaca ctctctttcacagatgtgaatctggagccctacatgatgtatgaatataggatttctgca tggaatcgctatgagcgaggattcagcaaggcagttagagccagaacaaaagaagatgtg cctgaaggagtgagtccccccaggtggacaaaaatggatcatcttgatgatgtaatagtc ttaagctggaagaaacctatacaatcaaatggtcctattattgcctacattcttctccga aatggaattgaatgttttcgaggaacatcactgagcttctctgatacggaaggaattcag ccctttatggaatattcataccagctgaaagcttgcacagttgctggctgtgctactagc agcaaggtcgttgcagctaccacccaaggaatcccgcagaatatccctccgcctagagtc acggcccccagtgcagaggctctgcatgtgagttggcatgtccctccgaagccaaatggc gtcattaaagagtaccagctcaggcaggtcgggaaaggtctcatctacactgacaccact gacaggaggcagcatacggtcacaggtctccagccatacaccaactacagcttcacactt agagcttgtacatctgctggatgcacttcaagtgagccttttctaggtcagactctgcag gcagcccctcaaggagtttgggtgacacctcgacacattgtagtcaattctacaacagtg gaattattttggagcccgccagaaaagcccaatggcctcatttctcaatatcagttgagt cgtaatggaagcttgattttcctggggggcagtgaggaacagaacttcactgataaaaac ctggagcccaacagcagatatgtttataagttagaagccacaactggaggtggcagcagt ccaagtgatgagtacattatacagacacctatattaacgccagaagaaatccagcctcca tataacatcacagtaatcgggccttattccatatttgtagcttggacaccaccagggatc cttgtccccaaaatgcctgtggagtacaatgtcttactcaatgctggaagtgcaacacct ctgatctcctctgttggtcatcatcaatccatccttctggaaaacttggctccattcaca cagtatgagataaggatacaagcatgccaaaaaggaggttgtggagttagcagtaggatg tttgccaaaacagctgaagctgcccccatggatctaaattcccctattcttaaggcactg gggtcagcttgcatagaggttaaatggatgccacctaaaaaaccaaatggagtcatcatc aactactttattcacagacgtcctactggcattgaagaggaatcccttgtgtttgtctgg tcagaaggagcccttgaatttattgacgatgcagacactttgaggcctttcacgctctat gagtatcgggtcagagcctgtaactccaggggctctgtggagagtccatggtcatcagca cgaactctggaagccccacctcaagatttcccggcaccttgggctcaagtcaccggtgcc cattcagttctgttgaactggaccgagccagactctcccaatggcatcatcttccagtat cgtgtggtttaccaacagaaaactgatgacccgaccttgaacttctctgctgtgcatgct ttcacagtgatgggaaccagctatcaagcccacctgtttggtttggaacccttcaccaca tatcacgtcggtgttgtggccacaaaccaggcaggagaagtttcaagcccctggactctg gttcagaccctcgaatcttcccccagtgggctgagcaacttcacagtggagcagaaagag aatgggagggcactgctgctgcagtggtcagagcctgcgagaaccaatggtgtgattaag acatacaatgtcttcagtgaggacatcctggagtacacaggcctgaatcgtcagtttctc ttccgacgcttggaccccttcacactctacaccctgaccctggaggcctgcaccagggcg ggctgtgcacactcggcgccccagccgctctggacggaggaagccgcccccgactctcag ccggcccccaccatccagtcggtgggctccaccagcgttgagctgagctggtcggagccc attaaacccaacggaaagataattcgctatgaagtgattcgcagatgcttcgagggaaaa gcttgggggaatcagacaatccaggctgatgagaaaattgttttcatagaatctaatact gagaggaatacatttatatataatgacacaggtctgcagccatggatgcagtgtgaatac aaagttcacacttggaactcagctggccacgcctgcagctcttggagtggggtgaggacc aggcaggcacctccagatggcctgtgtccacctgaggtagcccaggtatctgtgaatccc cccaaagtgctgattgcctgggtccctccagagcagcctaatggcatcatccagtcctac aggctgcagaggaatggaatgctctatcctttcagctttgatgctgtgactttcaattac acagatgagaagctgctccctttctccacttacagctatggggtcacagcctgcaccagc gggggctgctctgccagcacgaccaccagcatcacaacccttgaggctgcccctgcaggg gtccaccctccagctctgaggaccatcagcgccactcagataaatgtatcttggtccccg ccatcgattcagaatggagagatcactcagtatttactcaggttggatggtaaagagtat ctcgctgggcagaacctgactctgttggtttcccacctgcagccttatacgcagtataat ttctccctggtggcgtgtaccaagggaggctgcacagcgagcatgccagaatctgcctgg acaatggaggccccaccacagaacatggaccctccaaaactgcaagttacgggctcagaa tccatagaaatcacctggaaactgcccagaatcccaaatggccggatcagaagctatgag ctgaggagggatggaacaattgtgtacactggcctggaaactcggtaccatgactttact ctcaccccaggtgtggagtacggctatacggtgatggccaacaacagtcaagggggtgtt ttgagtccacttgtcaaagatcgaaccagcccctcagcgccttcagggatggaacctccg agattgctggccaagggccctcaggagatcttcgtgacctgggatcctccagtaaggaca aatggtcgtattgtcaactataccctcttcatccgtgacctgtttgaaagagaaacaaaa atcgtacacataaacacaactcataattcctttggtccacagtcgttcatggtaaaccag ttgaaaccatttcacaggtatgaagttcgaatccaagcctgcaccaggctgggctgtgtg tcaagtgactggacatccatagagaccctggaggttgcaccgcagcagcaaccccctccc catctagaggtgcagatggctccaggggggttccagcccaccgtttcccttctgtggaca ggacccctccaaccaaatggaaaagttttatattatgaattgtacagaagacaaatagca actcagcctgaaaagtcaaaaccagtgctagcctataatggaagctcaagctcttttatg gatgtcgaactactgccttttacagagtatgaataccaggtctgggccgtgaattcagca ggtaaagcccccagcagctggacgcggtgtagaactggacctgcccccccggaaggtctc aaggcccccaagttccacgcggtttctgccacccaagcagtggtcaacatcagcgccccc cagaagcccaacgggattgtcactctctacagattgttctccaggagcaccagcggggcc cagacagtgctggctgaaggcctggccacccagcagactcttcacagcctgcagcccttc acgacctactccattggggtggaggcctgcacttgcttcagttgttgtagccaagggcca acagcagagctgagaactcctcctgctccacccgcaggattgtcctctccgcaaatccag atgctggcctcaaggacagcctccttccagtggagtccgccactgtcccccaacggtgtt attcaaagctatgagctccaactctacaaggcatgccctccggattcagccaccccctgt acccccagacaaaccgagaccaagtacaagggtccagggcagagagccagcctcgagggt ctccagccctacaccacctacaagctgagggtagtggcccacaacgaggtgggcagcacg gccactgaatggatcagcttcgtcacccaaaaagaattgccgcagtaccgtgccccgttc tcagtggacagcaacctgtccgtggtgtgtgtgaactggagcaactccttcctgctgaac gggcggctgaaggagttcgtcctgaccgacggaggacagcgcctctacagtggcctcgac accaccctctatatcccgaggaccgcggacaaaactttcttttttcaggtcatctgcatt acagaagaaggaagtgctaagacgcctttgatccaatatgatacctccactggatttggc ctggtgctgacaactcctggagaaaagaaaggatcaagaagcaaaagcacggagttctac agcgagttgtggttcatagtgttaatggcagtgctgggcttgattttgttggccattttc ctgtccctgatactacagagaaaaatccacaaagaaccatatatcagagagaggcctccc ctagtgcctcttccaaaacgaaggtctccactgaatgtctacccacccggggaaacccat gtgggcttagctgataccaaaatcccccggtctgggacacctgtgagcattaggagcaac cgaagcctgtctgttctgcacatcccaagtcagagtcacggcagtcagacctattcccaa ggctctctccaccggagtgtcagccaactcatggacattcaagacaagaaggtcttgata gacgactcactgtgggaaaccatcatgggccatgacagcggactgtatgtggatgaagag gacctgatgaatgccatcaagggtttcagctctgtgactaaggaacacaccacattcacc gacacccacctgtga

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