Bison bison bison (American bison): 104999563 Help Entry 104999563         CDS       T08726                                  Symbol ADCY7 Name (RefSeq) adenylate cyclase type 7   KO K08047   adenylate cyclase 7 [EC:4.6.1.1] Organism bbis  Bison bison bison (American bison) Pathway bbis00230   Purine metabolism bbis01100   Metabolic pathways bbis01522   Endocrine resistance bbis04015   Rap1 signaling pathway bbis04020   Calcium signaling pathway bbis04022   cGMP-PKG signaling pathway bbis04024   cAMP signaling pathway bbis04062   Chemokine signaling pathway bbis04072   Phospholipase D signaling pathway bbis04081   Hormone signaling bbis04082   Neuroactive ligand signaling bbis04114   Oocyte meiosis bbis04211   Longevity regulating pathway bbis04213   Longevity regulating pathway - multiple species bbis04261   Adrenergic signaling in cardiomyocytes bbis04270   Vascular smooth muscle contraction bbis04371   Apelin signaling pathway bbis04540   Gap junction bbis04611   Platelet activation bbis04713   Circadian entrainment bbis04714   Thermogenesis bbis04723   Retrograde endocannabinoid signaling bbis04724   Glutamatergic synapse bbis04725   Cholinergic synapse bbis04727   GABAergic synapse bbis04750   Inflammatory mediator regulation of TRP channels bbis04911   Insulin secretion bbis04912   GnRH signaling pathway bbis04913   Ovarian steroidogenesis bbis04914   Progesterone-mediated oocyte maturation bbis04915   Estrogen signaling pathway bbis04916   Melanogenesis bbis04918   Thyroid hormone synthesis bbis04921   Oxytocin signaling pathway bbis04923   Regulation of lipolysis in adipocytes bbis04925   Aldosterone synthesis and secretion bbis04926   Relaxin signaling pathway bbis04927   Cortisol synthesis and secretion bbis04928   Parathyroid hormone synthesis, secretion and action bbis04934   Cushing syndrome bbis04935   Growth hormone synthesis, secretion and action bbis04970   Salivary secretion bbis04971   Gastric acid secretion bbis04972   Pancreatic secretion bbis04976   Bile secretion bbis05032   Morphine addiction bbis05163   Human cytomegalovirus infection bbis05166   Human T-cell leukemia virus 1 infection bbis05200   Pathways in cancer bbis05207   Chemical carcinogenesis - receptor activation bbis05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:bbis00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     104999563 (ADCY7)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     104999563 (ADCY7)    04371 Apelin signaling pathway     104999563 (ADCY7)    04020 Calcium signaling pathway     104999563 (ADCY7)    04072 Phospholipase D signaling pathway     104999563 (ADCY7)    04024 cAMP signaling pathway     104999563 (ADCY7)    04022 cGMP-PKG signaling pathway     104999563 (ADCY7)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     104999563 (ADCY7)    04081 Hormone signaling     104999563 (ADCY7)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     104999563 (ADCY7)   09144 Cellular community - eukaryotes    04540 Gap junction     104999563 (ADCY7)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     104999563 (ADCY7)    04062 Chemokine signaling pathway     104999563 (ADCY7)   09152 Endocrine system    04911 Insulin secretion     104999563 (ADCY7)    04923 Regulation of lipolysis in adipocytes     104999563 (ADCY7)    04912 GnRH signaling pathway     104999563 (ADCY7)    04913 Ovarian steroidogenesis     104999563 (ADCY7)    04915 Estrogen signaling pathway     104999563 (ADCY7)    04914 Progesterone-mediated oocyte maturation     104999563 (ADCY7)    04921 Oxytocin signaling pathway     104999563 (ADCY7)    04926 Relaxin signaling pathway     104999563 (ADCY7)    04935 Growth hormone synthesis, secretion and action     104999563 (ADCY7)    04918 Thyroid hormone synthesis     104999563 (ADCY7)    04928 Parathyroid hormone synthesis, secretion and action     104999563 (ADCY7)    04916 Melanogenesis     104999563 (ADCY7)    04925 Aldosterone synthesis and secretion     104999563 (ADCY7)    04927 Cortisol synthesis and secretion     104999563 (ADCY7)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     104999563 (ADCY7)    04270 Vascular smooth muscle contraction     104999563 (ADCY7)   09154 Digestive system    04970 Salivary secretion     104999563 (ADCY7)    04971 Gastric acid secretion     104999563 (ADCY7)    04972 Pancreatic secretion     104999563 (ADCY7)    04976 Bile secretion     104999563 (ADCY7)   09156 Nervous system    04724 Glutamatergic synapse     104999563 (ADCY7)    04727 GABAergic synapse     104999563 (ADCY7)    04725 Cholinergic synapse     104999563 (ADCY7)    04723 Retrograde endocannabinoid signaling     104999563 (ADCY7)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     104999563 (ADCY7)   09149 Aging    04211 Longevity regulating pathway     104999563 (ADCY7)    04213 Longevity regulating pathway - multiple species     104999563 (ADCY7)   09159 Environmental adaptation    04713 Circadian entrainment     104999563 (ADCY7)    04714 Thermogenesis     104999563 (ADCY7)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     104999563 (ADCY7)    05207 Chemical carcinogenesis - receptor activation     104999563 (ADCY7)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     104999563 (ADCY7)    05163 Human cytomegalovirus infection     104999563 (ADCY7)   09165 Substance dependence    05032 Morphine addiction     104999563 (ADCY7)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     104999563 (ADCY7)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     104999563 (ADCY7)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     104999563 (ADCY7) Enzymes [BR:bbis01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      104999563 (ADCY7) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N Motif Other DBs NCBI-GeneID:  104999563 NCBI-ProteinID:  XP_010853430 Ensembl:  ENSBBBG00000018007 UniProt:  A0A6P3IQK3 LinkDB All DBs Position Unknown AA seq 1096 aa AA seqDB search MLPRPWGFLRGPLGVPRWRMPAKGRYFLNEGEEGPDQDALYEKYRLTSQHGPLLLMLLLV AIAACTTLIVITFSYGDPSRHRAVLGTAFFTLAVFVLLYALVYVECLDRRGLRISALLIW ACLVTLGYVLVFDFDSPRKDTCVLGQVPFFLFVVFVVYTLLPFSTWGAVTAGLVSSISHL LVLTMHQEDFTSPVGLKLLATAVVFVCGNLTGAFHKHHMQDASHDLFTYTVKCIQIRRKL RIEKRQQXXXXXSVLPAHISMGMKLAIIERLKERGDRRYLPDNNFHNLYVKRHQNVSILY ADIVGFTRLASDCSPKELVVVLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPN HARNCVKMGLDMCEAIKQVREATGVDISMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLA NRMEAAGVPGRVHITEATLKHLDKAYEVEDGHGQQRDPYLKEMNIRTYLVIDPRSQQPPQ PSQHNSKNKGDATLKMRASVRMTRYLESWGAARPFAHLNQRESVSSSETLVSHGRRPKAV PLRRHRTPDRSASPKGRSEDDSYDDEMLSAIEGLSSTRPCCSKSDDFSTFGSIFLEKGFE REYRLAPIPRVRYYFACASLVFVCILLIHVLLLYSMKTLGVSFGLVACVLGLVLGLCFAD VFLRCCPALGKLRAIAESVETQPLLRVSLAILTIGSLLVIAVVNLPLMPFRDRGLTAGNE TGLRAVSGWEMSPCYLLPYYTCSCILAFIACSVFLRMSLELKVVLLTVALVAYLVLFNVY PSWQWDCCGHSLGNLTGTNGTLSSSSCSWHLKTMTNFYLVLFYTTLIMLSRQIDYYCRLD CLWKKKFKKEHEEFETMENVNRLLLENVLPAHVAAHFIGDKLNEDWYHQSYDCVCVMFAS VPDFKVFYTECDVNKEGLECLRLLNEIIADFDELLLKPKFSGVEKIKTIGSTYMAAAGLS VPPGPENQDLERQHAHIGIMVEFSTALMSKLDGINRHSFNSFRLRVGINHGPVIAGVIGA RKPQYDIWGNTVNVASRMESTGELGKIQVTEETCTILQGLGYSCECRGLIDVKGKGELRT YFVCTDTAKFQGLGLN NT seq 3291 nt NT seq  +upstreamnt  +downstreamnt atgctccccaggccgtggggtttcctgcgtggaccactgggtgtgccaaggtggaggatg ccagccaaggggcgctacttcctcaacgagggcgaggagggccccgaccaggatgcgctc tacgagaagtaccgcctcaccagccagcacgggccactcctgctcatgctcctcttggtg gccatcgctgcctgcaccacgctcatcgtcatcaccttcagctacggggacccctccaga caccgggccgtcctggggacggcgttcttcacgctcgccgtgtttgtgctcctctacgct ctggtgtacgttgagtgcctcgaccggcgggggctcaggatttccgcgctgctcatctgg gcctgccttgtgacgctgggctacgtgttggtgtttgatttcgactcgccgaggaaggac acctgtgtcttggggcaggtgcccttcttcctgttcgtggtcttcgtggtgtacacgctg ctgcccttcagcacgtggggcgccgtcacggccggactcgtctccagcatctcccacctc ctggtgctcacaatgcaccaggaagacttcaccagccctgtggggctgaagctgctggcc actgcggtggtcttcgtgtgcgggaacctcacaggcgccttccacaagcaccacatgcag gacgcctcccacgacctcttcacctacacagtgaagtgcatccagattcggcgtaagctg cgcatcgagaagcgccagcagnnnnnnnnnnnnnngtctgtgctgcctgcccacatctcc atgggcatgaagctggccatcatcgagcggctcaaggagcgcggggaccgccgttacctg cccgacaacaacttccacaacctctacgtcaagaggcaccagaatgtcagcatcctctac gctgacatcgtgggcttcacgcgactggccagtgactgctcccccaaagagctggtggtg gtgctgaatgagctcttcggcaagtttgaccagatcgccaaggccaacgagtgcatgcgg attaagatcctgggcgactgctactactgcgtgtccggcttgcctgtgtccctgcccaac cacgcccgtaactgtgtgaagatggggctggacatgtgtgaggccatcaagcaggtgcgg gaggccacaggcgtggacatcagcatgcgcgtgggcatccactcggggaacgtgctgtgc ggcgtcatcgggctgcgcaagtggcagtacgacgtgtggtcccacgatgtgtccctggcc aacaggatggaggcggccggagtccctggccgggtgcacatcacagaggcgacgctgaag cacctggacaaggcgtacgaggtggaggacgggcacgggcagcagcgggacccttacctc aaggagatgaacatccgcacctacctggtcatcgacccccggagccagcagccgccccag cccagccagcacaactccaagaacaagggggacgcgaccctgaagatgcgggcgtccgtg cgcatgacgcgctacctggagtcctggggggcggctcgccccttcgcgcacctcaaccaa cgcgagagcgtgagcagcagtgagacccttgtgtcccatgggcggaggcccaaggctgtt cccctgaggcgccaccggacccctgacagaagcgcatcccccaaggggcggtcagaggac gactcatacgatgatgagatgctgtcagccatcgaggggctcagctctaccagaccctgc tgctccaagtctgatgacttctccacctttgggtccatcttcctggagaagggctttgag cgagagtaccgcctggcgcccatcccccgggtccgctactacttcgcttgtgccagcctc gtcttcgtctgcatcctgctcatccacgtcttgctgttgtacagtatgaagactctgggc gtgtcctttgggctggtggcctgtgtgctcgggctggtactaggcttgtgcttcgccgat gtgttcttgaggtgctgcccggccctggggaagctccgagccattgctgagagcgtggag acgcagcccctgctgcgggtgtccctggccatcctgaccatcggcagcctgctcgtcatt gctgtcgtcaacctgcccctgatgcccttccgggaccgggggctgactgctgggaacgag acgggcctgagggctgtgagcggctgggagatgagcccgtgctacctcctcccgtactac acctgcagctgcatcctggccttcatcgcttgctctgtcttcctgcggatgagcctggag ctgaaggtcgtgctgctgaccgtggccttggtggcctacctggtcctcttcaacgtctac ccgagctggcagtgggactgctgtggccacagcctgggcaacctcaccgggaccaatggc accctcagctcctcatcctgttcatggcatctgaagacgatgaccaatttctacctggtc ttgttctacaccaccctcatcatgctctccagacagattgactattattgccgcctggac tgtctgtggaagaagaagttcaagaaggaacacgaggagtttgaaacaatggagaatgtg aaccgccttcttctagagaatgtcctgcccgcgcacgtggccgcccacttcatcggtgac aagttaaatgaggactggtaccatcagtcctacgactgcgtgtgtgtcatgtttgcgtcg gtgccggactttaaagtcttctacacagagtgcgacgtcaacaaggaagggctggagtgc ctgcgcctgctcaacgagatcatcgccgactttgacgagctgctgctaaagcccaagttc agtggtgtggagaagatcaagaccatcggcagcacgtacatggccgccgcggggctcagc gtccccccggggcctgagaaccaggacctggagcggcagcacgcccacatcggcatcatg gtggagttcagcaccgccctgatgagcaagctggacggcatcaatcggcactccttcaac tcctttcgcctccgagtcggcataaaccatgggcctgtgattgctggagtgattggggca cgaaaacctcagtacgacatctggggaaacacggtcaatgttgccagtcgaatggagagc actggagaacttggaaaaatccaggttactgaagagacatgtaccatcctccagggacta gggtattcctgtgagtgccgcgggctgattgatgtcaaaggcaaaggtgaactgaggact tactttgtctgtacggacaccgccaagttccaaggcctggggctgaactga

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