KEGG   Bison bison bison (American bison): 104999734
Entry
104999734         CDS       T08726                                 
Symbol
IL12B
Name
(RefSeq) interleukin-12 subunit beta
  KO
K05425  interleukin 12B
Organism
bbis  Bison bison bison (American bison)
Pathway
bbis04060  Cytokine-cytokine receptor interaction
bbis04620  Toll-like receptor signaling pathway
bbis04622  RIG-I-like receptor signaling pathway
bbis04625  C-type lectin receptor signaling pathway
bbis04630  JAK-STAT signaling pathway
bbis04658  Th1 and Th2 cell differentiation
bbis04936  Alcoholic liver disease
bbis04940  Type I diabetes mellitus
bbis05133  Pertussis
bbis05134  Legionellosis
bbis05140  Leishmaniasis
bbis05142  Chagas disease
bbis05143  African trypanosomiasis
bbis05145  Toxoplasmosis
bbis05146  Amoebiasis
bbis05152  Tuberculosis
bbis05162  Measles
bbis05164  Influenza A
bbis05168  Herpes simplex virus 1 infection
bbis05171  Coronavirus disease - COVID-19
bbis05200  Pathways in cancer
bbis05205  Proteoglycans in cancer
bbis05321  Inflammatory bowel disease
bbis05330  Allograft rejection
bbis05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:bbis00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    104999734 (IL12B)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    104999734 (IL12B)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    104999734 (IL12B)
   04622 RIG-I-like receptor signaling pathway
    104999734 (IL12B)
   04625 C-type lectin receptor signaling pathway
    104999734 (IL12B)
   04658 Th1 and Th2 cell differentiation
    104999734 (IL12B)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    104999734 (IL12B)
   05205 Proteoglycans in cancer
    104999734 (IL12B)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    104999734 (IL12B)
   05164 Influenza A
    104999734 (IL12B)
   05162 Measles
    104999734 (IL12B)
   05168 Herpes simplex virus 1 infection
    104999734 (IL12B)
  09171 Infectious disease: bacterial
   05133 Pertussis
    104999734 (IL12B)
   05134 Legionellosis
    104999734 (IL12B)
   05152 Tuberculosis
    104999734 (IL12B)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    104999734 (IL12B)
   05145 Toxoplasmosis
    104999734 (IL12B)
   05140 Leishmaniasis
    104999734 (IL12B)
   05142 Chagas disease
    104999734 (IL12B)
   05143 African trypanosomiasis
    104999734 (IL12B)
  09163 Immune disease
   05321 Inflammatory bowel disease
    104999734 (IL12B)
   05330 Allograft rejection
    104999734 (IL12B)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    104999734 (IL12B)
  09167 Endocrine and metabolic disease
   04940 Type I diabetes mellitus
    104999734 (IL12B)
   04936 Alcoholic liver disease
    104999734 (IL12B)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:bbis04052]
    104999734 (IL12B)
   00536 Glycosaminoglycan binding proteins [BR:bbis00536]
    104999734 (IL12B)
Cytokines and neuropeptides [BR:bbis04052]
 Cytokines
  Interleukins
   104999734 (IL12B)
Glycosaminoglycan binding proteins [BR:bbis00536]
 Heparan sulfate / Heparin
  Cytokines
   104999734 (IL12B)
SSDB
Motif
Pfam: IL12p40_C Ig_5 Ig_3 Ig_4 Ig_2 fn3 I-set ig
Other DBs
NCBI-GeneID: 104999734
NCBI-ProteinID: XP_010853605
Ensembl: ENSBBBG00000022374
UniProt: A0A6P3IGX9
LinkDB
Position
Unknown
AA seq 327 aa
MHPQQLVVSWFSLVLLASPIVAIWELEKNVYVVELDWYPDAPGETVVLTCDTPEEDGITW
TSDQSSEVLGSGKTLTIQVKEFGDAGQYTCHKGGEALSRSLLLLHKKEDGIWSTDILKDQ
KEPKAKSFLKCEAKDYSGHFTCWWLTAISTDLKFSVKSSRGSSDPRGVTCGAASLSAEKV
SMEHREYNKYTVECQEGSACPAAEESLLIEVVVEAVHKLKYENYTSSFFIRDIIKPDPPK
NLQLRPLKNSRQVEVSWEYPDTWSTPHSYFSLTFCVQVQGKNKREKKLFMDQTSAKVTCH
KDANVRVQARDRYYSSFWSEWASVSCS
NT seq 984 nt   +upstreamnt  +downstreamnt
atgcaccctcagcagttggtcgtttcctggttttccctggttttgctggcatctcccatc
gtggccatatgggaactggagaaaaatgtttatgttgtagaattggattggtatcctgat
gctcctggagaaacagtggtcctcacgtgtgacactcctgaagaagacggcatcacctgg
acctcagaccagagcagtgaggtcttgggctctggcaaaaccttgaccatccaagtcaaa
gagtttggagatgctgggcagtacacctgtcacaaaggaggcgaggctctgagtcgttca
ctcctcctgctgcacaaaaaggaagatggaatttggtccactgatattttaaaggatcag
aaagaacccaaagctaagagttttttaaaatgtgaggcaaaggattattctggacacttc
acctgctggtggctgacagcaatcagtactgatttgaaattcagtgtcaaaagcagcaga
ggctcctctgacccccgaggggtgacgtgcggagcagcgtcgctctcagcagagaaggtc
agcatggagcacagggagtataacaagtacacagtggagtgtcaggagggcagcgcctgc
ccggccgccgaggagagcctgcttattgaggtcgtggtagaagctgtgcacaagctcaag
tatgaaaactacaccagcagcttcttcatcagggacatcatcaaaccagacccacccaag
aacctgcaactgagaccattaaagaattctcggcaggtggaggtcagctgggagtaccct
gacacgtggagcacccctcattcctacttctccctgacgttttgtgttcaggtccaggga
aagaacaagagagaaaagaaactcttcatggaccaaacctcagccaaagtcacatgccac
aaggatgccaacgtccgcgtgcaagcccgggaccgctactacagctcattctggagtgaa
tgggcatctgtgtcctgcagttag

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