KEGG   Bison bison bison (American bison): 105000295
Entry
105000295         CDS       T08726                                 
Symbol
MAP2K6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6 isoform X1
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
bbis  Bison bison bison (American bison)
Pathway
bbis04010  MAPK signaling pathway
bbis04015  Rap1 signaling pathway
bbis04218  Cellular senescence
bbis04380  Osteoclast differentiation
bbis04620  Toll-like receptor signaling pathway
bbis04664  Fc epsilon RI signaling pathway
bbis04668  TNF signaling pathway
bbis04750  Inflammatory mediator regulation of TRP channels
bbis04912  GnRH signaling pathway
bbis04935  Growth hormone synthesis, secretion and action
bbis04936  Alcoholic liver disease
bbis05014  Amyotrophic lateral sclerosis
bbis05022  Pathways of neurodegeneration - multiple diseases
bbis05132  Salmonella infection
bbis05135  Yersinia infection
bbis05145  Toxoplasmosis
bbis05161  Hepatitis B
bbis05163  Human cytomegalovirus infection
bbis05167  Kaposi sarcoma-associated herpesvirus infection
bbis05169  Epstein-Barr virus infection
bbis05170  Human immunodeficiency virus 1 infection
bbis05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
bbis05417  Lipid and atherosclerosis
bbis05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:bbis00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105000295 (MAP2K6)
   04015 Rap1 signaling pathway
    105000295 (MAP2K6)
   04668 TNF signaling pathway
    105000295 (MAP2K6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    105000295 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    105000295 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    105000295 (MAP2K6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    105000295 (MAP2K6)
   04935 Growth hormone synthesis, secretion and action
    105000295 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    105000295 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    105000295 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    105000295 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    105000295 (MAP2K6)
   05161 Hepatitis B
    105000295 (MAP2K6)
   05163 Human cytomegalovirus infection
    105000295 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    105000295 (MAP2K6)
   05169 Epstein-Barr virus infection
    105000295 (MAP2K6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    105000295 (MAP2K6)
   05135 Yersinia infection
    105000295 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    105000295 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    105000295 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    105000295 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105000295 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    105000295 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    105000295 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:bbis01001]
    105000295 (MAP2K6)
Enzymes [BR:bbis01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     105000295 (MAP2K6)
Protein kinases [BR:bbis01001]
 Serine/threonine kinases: STE group
  STE7 family
   105000295 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Seadorna_VP7 Haspin_kinase Choline_kinase DUF4344 APH
Other DBs
NCBI-GeneID: 105000295
NCBI-ProteinID: XP_010854381
Ensembl: ENSBBBG00000023324
UniProt: A0A6P3IJ42
LinkDB
Position
Unknown
AA seq 334 aa
MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIVELG
RGAYGVVEKMRHVPSEQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALF
REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
KPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSEEFVDFTSQCLKKNSK
ERPTYPELMQHLFFTLHESKATDVASFVKSILGD
NT seq 1005 nt   +upstreamnt  +downstreamnt
atgtctcagtcgaaaggcaagaagcgaaaccctggccttaaaattcccaaagaagcattt
gaacaacctcagaccagttccacgccaccgcgggatttagactccaaagcttgcatttct
attggaaatcagaactttgaggtgaaggcagatgacctggagcccatcgtggagctgggc
cggggggcgtacggggtggtggagaagatgcggcatgtgcccagcgagcagatcatggcg
gtgaagcggatccgggccacggtaaacagccaagagcagaagcggctcctgatggatctg
gatatctccatgaggaccgtggactgtcccttcacggtcaccttttacggcgcactcttc
cgtgagggggatgtctggatctgcatggagctcatggacacgtccctagataaattctac
aaacaagtgatcgataaaggccaaacaattccagaggacatcttagggaaaatagcagtt
tctattgtaaaagccttagagcatttgcacagtaagctgtctgtcattcaccgagatgtc
aagccctccaacgtgctcatcaacgctctgggccaggtgaagatgtgcgacttcggaatc
agcggctacctggtcgactccgtggctaaaaccatcgatgccggatgcaaaccgtacatg
gcccccgagagaataaacccagagctcaaccagaagggatacagcgtgaagtccgacatc
tggagtttgggcatcaccatgatcgagctggccatcctccggtttccctacgactcgtgg
gggactcctttccagcagctcaaacaggtggtggaggagccttcgccgcagctgcccgca
gacaagttctccgaagagtttgttgactttacctcacagtgcttgaagaagaattccaaa
gaaaggccaacatatccagagcttatgcaacatctgtttttcaccctacacgaatccaaa
gcgacagacgtggcatcttttgtaaaatcaattcttggagactaa

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