Bison bison bison (American bison): 105000492
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Entry
105000492 CDS
T08726
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
bbis
Bison bison bison (American bison)
Pathway
bbis04140
Autophagy - animal
bbis04141
Protein processing in endoplasmic reticulum
bbis04210
Apoptosis
bbis04932
Non-alcoholic fatty liver disease
bbis05010
Alzheimer disease
bbis05012
Parkinson disease
bbis05014
Amyotrophic lateral sclerosis
bbis05016
Huntington disease
bbis05017
Spinocerebellar ataxia
bbis05022
Pathways of neurodegeneration - multiple diseases
bbis05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
bbis00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
105000492 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
105000492 (ERN1)
09143 Cell growth and death
04210 Apoptosis
105000492 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
105000492 (ERN1)
05012 Parkinson disease
105000492 (ERN1)
05014 Amyotrophic lateral sclerosis
105000492 (ERN1)
05016 Huntington disease
105000492 (ERN1)
05017 Spinocerebellar ataxia
105000492 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
105000492 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
105000492 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
105000492 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
bbis01001
]
105000492 (ERN1)
Enzymes [BR:
bbis01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
105000492 (ERN1)
Protein kinases [BR:
bbis01001
]
Serine/threonine kinases: Other
IRE family
105000492 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
APH
Band_3_cyto
Motif
Other DBs
NCBI-GeneID:
105000492
NCBI-ProteinID:
XP_010854720
Ensembl:
ENSBBBG00000001408
UniProt:
A0A6P3IU75
LinkDB
All DBs
Position
Unknown
AA seq
974 aa
AA seq
DB search
MLVRLLLLLLALLLPGPGGFGSPSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDP
VLQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYMGK
KQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYF
DYAAALPEDGGDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYIWQREGLRKV
MHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSMV
HEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKGKSKLNYLRNYWL
LIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVIDLVDQTSENAPTTVSP
DVEEKFDHAPAKPEAPVDSMLKDMATIILSTFLLIGWVAFIITYPLSIHQQRQLQHQQFQ
KELEKIQLLQQQQLPFHPPGDAAQDAELQDSSGQYSESSATSSPNTSPRASNHSLHSTGS
TSKAVTSPFLEQDDEDEETGMVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRIL
PECFSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKDFAHLG
LEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLAVGR
HSFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQ
ANILLGAYSLDCLHPSSAEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFF
QDVSDRIEKEALDGPIVKQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGSSVRDLLR
AMRNKKHHYRELPEEVQQTLGALPDDFVRYFTSRFPPLLSHTYRAMELCCHERPFQPYYH
EPPEPQPPVTADAL
NT seq
2925 nt
NT seq
+upstream
nt +downstream
nt
atgcttgtccgattgctgctgctgctgctggcattgctgttgcccggccccgggggtttt
gggagtcccagcactgtgacacttcctgaaaccttgctgtttgtgtccacattggatgga
agtctgcatgccgtcagcaagaggacaggctccatcaaatggactttaaaggaagatcca
gtcctgcaggttccaacacatgtggaagagcctgccttcctcccagatcccaacgatggc
agcctgtacacgcttgggggcaagaacaacgaaggcctgacgaaacttccctttacgatc
cctgagttggtgcaggcatctccgtgccgaagttcagatggcattctctacatgggtaaa
aagcaggacatttggtacgttatcgacctcctgactggggagaagcagcagaccctgtca
tcagcctttgcagacagcctctgcccatcaacctctcttctgtatctggggcgaacagag
tacaccatcaccatgtacgacaccaagacccgcgagctgcgctggaacgccacctacttt
gactacgcggccgcgctgcccgaggacggtggggactacaagatgtcccactttgtgtcc
aatggcgatgggctggtggtgacggtggacagcgagtctggggacgtcctgtggatccaa
aactatgcttcccccgtggtggccttttacatctggcagcgcgagggcctgcggaaggtg
atgcacatcaacgtcgccgtggagaccctgcgctacctgaccttcatgtcgggggaggtg
gggcgcatcaccaagtggaagtacccgttccccaaggagacggaggccaagagcaagctg
acgcccaccctgtatgtggggaaatactccaccagcctctatgcttccccctcaatggtg
catgagggcgtcgccgttgtgccccggggcagcacccttcctttgctggaaggcccccag
accgacggtgtcaccatcggggacaaaggggagtgtgtgatcacgcccagcacggacctg
aagttcgacccaggactcaaaggcaagagcaagctcaactacctgcggaactactggctg
ctcatcggacaccacgaaaccccactgtccgcatccaccaagatgctggagcgcttcccc
aacaacctgcccaaacaccgggagaacgtgattcccgccgactcggagaagaagagcttt
gaggaggtcattgacctggttgaccagacttcagaaaatgcacctaccacggtttctccg
gacgtggaagagaagttcgatcatgcccctgccaagcccgaggcccctgtggactccatg
ctcaaggacatggccaccatcatcctgagcaccttcctgctcatcggctgggtggctttc
atcatcacttaccccctgagcatccaccagcagcgacagctccagcaccagcagttccag
aaggaactggagaagatccagctcctgcagcagcagcagctgcccttccacccgcccggg
gatgcggcacaggacgctgagctccaggactcatccggccagtactcggagagctcggcc
accagcagccccaacacgtccccccgagcctccaaccactcgctgcactccaccggctcc
acctccaaggctgtcaccagccccttcctggagcaggacgatgaggatgaggagaccggc
atggtgatagttgggaaaatctccttctgtccaaaggatgtcctgggccatggagctgag
ggcacgatcgtgtaccggggcatgtttgacaaccgtgacgtggcagtcaagaggatcctg
cccgagtgtttcagtttcgcggaccgtgaggtccagctgctgagagagtcggacgagcac
ccaaacgtgatccgctacttctgcactgagagggaccggcagttccagtacatcgccatc
gagctgtgcgcggccacgctgcaggagtacgtggagcagaaggatttcgcccacctcggc
ctggagcccatcaccctgctgcaacagaccacctcgggcctggcccacctgcactccctc
aacatcgttcacagagacctgaagccccacaacatcctcctctccatgcccaacgcacac
ggcaggatcaaggccatgatctccgacttcggcctctgcaagaagctggccgtgggcagg
cacagcttcagccgccgctcgggggtgccgggcaccgaaggttggatcgccccggagatg
ctgagcgaagactgcaaggagaaccccacctacacggtggacatcttctccgcgggctgc
gtcttctactacgtgatatctgagggcagccacccctttggcaagtccctgcaacgccag
gccaacatcctcctgggtgcctacagccttgactgcctgcacccctcctctgcagaggac
gtcattgcccgggaattaatagagaagatgatcgccatggacccccagaagcgcccgtca
gcgaagcatgtgctgaaacaccctttcttctggagcctggaaaagcagctccagttcttc
caggacgtgagtgaccggatagagaaagaggccctggacggcccgatagtgaagcagctg
gagcgcggcgggcgggccgtggtgaagatggactggcgggagaacatcaccgtccccctg
cagacagatctgcggaaattcagaacctataaaggcagttcggtccgagatctcctcaga
gccatgaggaataagaagcaccactaccgggagctgcccgaggaggtgcagcagacgctg
ggcgccctccctgacgacttcgtgcgctacttcacctcccgcttcccccccctcctctca
cacacctaccgtgccatggagctgtgctgccacgagaggcccttccagccctactaccac
gagccccccgagccccagccccccgtgactgcagatgccctctga
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integrated database retrieval system
