Bison bison bison (American bison): 105000777
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Entry
105000777 CDS
T08726
Symbol
SETX
Name
(RefSeq) probable helicase senataxin isoform X1
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
bbis
Bison bison bison (American bison)
Pathway
bbis05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
bbis00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
105000777 (SETX)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
bbis03021
]
105000777 (SETX)
Enzymes [BR:
bbis01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
105000777 (SETX)
5.6.2.5 RNA 5'-3' helicase
105000777 (SETX)
Transcription machinery [BR:
bbis03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
105000777 (SETX)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
AAA_11
AAA_12
AAA_19
AAA_30
UvrD-helicase
AAA_22
ResIII
Helicase_RecD
SLFN-g3_helicase
nSTAND3
UvrD_C_2
AAA_16
Motif
Other DBs
NCBI-GeneID:
105000777
NCBI-ProteinID:
XP_010855080
Ensembl:
ENSBBBG00000009759
UniProt:
A0A6P3IVA3
LinkDB
All DBs
Position
Unknown
AA seq
2683 aa
AA seq
DB search
MVPSSKNADEINKTAFQKKCRMSTCCWCTPGGTSTTDFLQRYASRTHSSEFQTADEDLCY
CLECVAEYHKARDELPFLHEVLWELETLRLINHFERSMKAEIGDDDELYIVDNNGEAQLF
DFTGQDFENKLRVPLLEILKYPYLLLHEHVNELCVEALCRMEQANCSFQVFDKHPGIYLF
LVHPNEMVRRWAILTARNLGKVDRDDYYDLQEVLTCLFKVIELGLLENPDIYTSSVLEKG
KLVLLPSHMYDTANYKNYWLGICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMERQSN
DNSVDPFWPALHCFMVILDRLGSKVWGQLIDPIEAFQTIINNVSYNREIQNIRNSSVRTK
LEPESYLDDMVTCSQIVYNYNPEKTKKDSGWRSAICPDYCPNMYEEMETLANVLQSDIGQ
DMRVHNSTFLWFIPFVQSLMDLKDLGVAYIVEVIHHLYSEVKDVLNQTDAVCDKVTEFFL
LILVSVIELHRNKKCLHLLWVSSQQWVEAVVKCAKLPTTAFARSSEKSSGNCSKGTAMIS
SLSLHSMPSNSVQLACVQLIRSLLKEGYQLGQQTLCKRFWDKLNLFLRGNLSLGWQLTSQ
ETHELQTCLKQIIRNIKFKVPQCSTFVDLNPACKTPPASYKEESEQIGKKSEKDVHCLEN
SSPTSSKEPMKADAYQVQESILSKANNAIEESKEPYYIKDLKLEGHLSAESCLKLSSKNL
ACERVQNQVKISTGKYKSVKENSSCTPQNGTLRNGPEKVFDRGIIISRRLLTVSSTDSLE
KVSASDEDFSLKEDGLGKSSKAKSKTHKDGVCAKLSHVIKKQRRRSISLEENLTVSSIEG
FYSKKDIGGQKGGGNICNPSLVPNGILDDKNGEQKSQSCLLLKKKEVKKEKLDLFSTPEN
SCQIQECHVDSKDLVSLTEMTNICMTNASPFKEPVTGHELRDRKISRSTDQFSSNLREQD
LSSSPQPDTLTDSQVDRDLHKLSLIAQASVTKFPSDSTEKSLSQIQRKVKDEKRCFTANQ
NVRETCCGQVIIISDSDDDEDEERILGLKKQMREVKACIEKECPEQHTSIANTNVEQKVL
IKEENPVSLLEFEESDSQFFEFETPCEVFSVWHDQKPDKNSAQENEKNPCSTHVGDSAND
LGYETDYVPEEVIKKVAENFEERTKPRSSSTSVEEFCEIEVKKPKRRRYEKPIAEDPLRP
SSSSVKNEDQSDILNKGNLSKNDVKGVDTRSTVPSSSVQRNTVVSPKKSLPKPRMYSKPV
RKVPVVKASKKSHSDTKKGQSKSSHYISCRTTPAIVPPKKFRQCPEPTSTVEKLGLKKAP
RRAFELSQRSLECIVQLRDHGKTVGVVDTRKKTKLISPQTLSVRNNKKLLTSQDLQLQRQ
MRSKSQQNRQRFDCRSTDRTRAGPRAAQSSAVPESSKSDYSHGGAEVTANNKGKQLLTCQ
SSETEPVKANQCNPVIVNGRIATNEVIVPTSEDLLDRGDLTVHHLEVATLKEGEPQFSSD
IEEDDIFLTQRDPEDMDLCSQIERENDKLIEVIHGKDTVQGEEECVSQPQLESLSSTKCK
YKDCVETLKNPGEYCSKHSKTKATDEDVFRKPGLPLSASKRSRPSTTKVFSSSSTSRIAG
LSKSLESTAALPSSLKNKSSGAQSVLKGPQPPLTVSLKPVAEVKGLCNVFPAQTPNNSNR
QVLRVPFGESRPFLTSSPVNILTSSQSISDTFVKEVLKWRYEMFVNFDQCGPPSSLCQSI
ERRVPIRFQDCGDYFNVFFPLMVLNTFETVAQEWISSPNKEKFHQLHLRKFPGDYKKYWE
FVVYLEECELAKQLHPRENDLVFLVPERLNEEKKDLEWSHLEDACEYYCGYVHKFRRTSV
MHNGKFECSVSIQTQDNLPVNLNELVKCFVISSLVTTQRKLKAMSLLSGRNQLARAILNP
NPMDFCTKDLPTATSERIVAYLKDFNEDQKKAIETACAMVKHSPSVAKICLIHGPPGTGK
SKTIVGILYRLLTENQRRGYSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCK
DKKNPMGNCGDINLVRLGPEKSINNEVLKFSLDSQVNHRMKKDLPSHVQEMHKRKEFLDR
QLDELSRQRALCRGGRESQRQELDGKIARVSKERQELASKIKEVQGRPQKTQSIIILESH
IICCTLSTSGGLLLEAAFRGQGGVPFSCVIVDEAGQSCEVETLTPLIHRCNKLVLVGDPK
QLPPTVISVKAQDYGYDQSMMARFHKLLEESVEHNMIGRLPVLQLTIQYRMHPDICLFPS
SYIYDGILRTNRGTETSRCSSDWPFQPYLVFDVGDGLERRDNDSYVNVQEIKLVMELIKL
IKDKRRDVTFRNIGIITHYKAQKTMIQKDLDKEFDRKGAAEVDTVDAFQGRQKDCVIVTC
VRANATQGSIGFLASLQRLNVTITRAKYSLFILGHLRTLVENRHWYHLIQDAQKRGAIIK
TCDKNYRHDAMKILKLKPLLQRSLTHPPAVAPEASRPQGGLPSSKQDGELSKTSFASSLY
HSPSDSKEATVTEAAKDPERPPNQDWLRDPRLLRRMGLALDAQGISLREPQPLSPQHSGA
APPLGAPGCPGSPQEPGSIRQQGVTLNNHTPHMQCDSPVASTDTSTSKKKCDQEEGVLSH
RRETRSLSVGDQEWWASSHAKRNSDWDERVLEEDSCSKKRRVL
NT seq
8052 nt
NT seq
+upstream
nt +downstream
nt
atggttcccagcagtaaaaacgctgatgaaattaacaaaactgccttccagaagaagtgc
agaatgagtacatgttgttggtgtaccccaggtggtacctccaccactgacttcctacaa
cgctatgcatccaggacccactccagtgaatttcagacagctgatgaagacctctgctac
tgcttggagtgtgtggctgaataccacaaagcaagggacgaattgccgttcttacatgag
gttttatgggaattagaaaccttacgtctcataaatcactttgaaagatccatgaaggca
gaaattggagatgatgatgagttatatatagtagacaacaacggagaggcacagctgttc
gatttcactggccaagactttgaaaataagcttcgagttcctcttcttgaaatactgaaa
tatccatatctgcttttacatgagcatgtcaatgaattatgtgttgaagcactttgccgg
atggaacaagctaattgctcctttcaagtttttgacaaacatccagggatctatttattt
ttggttcatcccaatgaaatggttcggcgttgggctatcctgactgcaagaaacttgggg
aaagtggatagagatgattactatgacttacaggaggttttgacttgcctttttaaagtt
attgagttgggacttttagaaaacccagacatttatacttcttctgtccttgagaagggt
aaactggttcttctgccttcacacatgtatgatactgccaactacaaaaactattggtta
ggtatctgtatgctgctgaccattcttgaagagcaagccatggattcactgttgttgggc
tcagataaacagaatgattttatgcagtcaatacttcacaccatggagaggcaatcaaat
gataatagtgtggatcctttctggccagcattacactgtttcatggtgattctggatcgc
cttggatctaaggtctggggtcaacttattgatcctattgaagcatttcaaaccattatt
aacaacgtgagctacaatagagagatccagaacatacggaacagctctgtgaggaccaag
ttagaaccggagtcatatttggatgatatggtgacttgcagccagattgtatacaattat
aatcctgaaaagaccaaaaaggattcggggtggagatcagccatttgccctgattattgt
cctaacatgtatgaagaaatggaaacattagctaacgtgctccagtcagacattggtcag
gacatgcgtgttcataacagcacatttctgtggttcatccctttcgtgcaatccctcatg
gacctgaaggatctgggtgtggcttacatagtggaggttattcaccatctgtactctgaa
gtcaaagatgttctcaaccagacagacgctgtgtgtgacaaagtcactgagtttttcctt
ctgattttggtgtccgtgattgaactgcatagaaataaaaaatgtctacatttgctgtgg
gttagttcccagcagtgggtggaggctgtggtgaagtgtgccaagctcccaaccacagcg
tttgcacggagttctgagaagtcatctggaaactgttccaaaggcacagcaatgatatca
tccctgtcactgcattcaatgccctccaactctgtgcagctggcttgtgtgcagctgatt
agaagtctcctgaaagaaggctatcagcttgggcagcagactctctgtaagcggttctgg
gataagctcaacttattcctgcgagggaatttatctttaggttggcagttgactagtcag
gaaacccatgagctacaaacttgtttaaagcaaattattaggaacataaaatttaaagta
cctcagtgtagcacttttgtggatctgaatcctgcatgtaagacgcctcctgcatcttat
aaagaagaaagtgaacaaatagggaagaagtctgaaaaagatgtgcactgtctagaaaat
tccagcccaacatcttctaaagaaccaatgaaagctgatgcatatcaagtgcaagagagt
attttgagcaaagcaaacaatgccatagaagagagtaaagagccatattatataaaagat
ttgaaactagaaggccacctctcagctgagtcatgtttgaaactgagtagtaaaaacctt
gcctgtgaaagagttcaaaatcaagttaaaataagtacagggaaatacaagtctgtaaaa
gagaattcctcatgtaccccacagaatggtactttaagaaatggtccagaaaaagtattt
gacagaggaataataatatcaaggcgcttattgactgtttctagcacggattctctggaa
aaagtgtctgcctccgatgaggacttctcgttaaaggaagatggtcttggcaaaagctca
aaagcaaaatctaagacacataaagatggagtctgtgctaagttgtcacatgtaataaaa
aagcaacgcaggagaagtatcagtttagaggaaaacctgactgtatctagcattgagggt
ttctattcaaagaaagatataggaggtcagaaaggaggtggaaacatatgcaatccttct
ttagtccctaatggtattctggatgataaaaatggagaacaaaaatctcaaagctgttta
ctgctgaaaaagaaagaagtaaagaaagaaaagttagatcttttctctacccctgaaaac
agttgtcaaatacaggaatgtcatgttgatagcaaagatttggtctcactcacagaaatg
accaatatctgcatgacgaatgcatctccctttaaagagcctgtgactggacatgaattg
agagataggaaaattagtaggagcactgatcagttttcttctaatttaagagaacaggac
cttagcagcagtccccagcctgacaccttaacagattctcaggtagatagagacctccac
aaattatctttaatagctcaagccagtgttactaagttcccatcagattcaactgaaaaa
agtttatcccaaatacaaagaaaagtaaaagatgagaaaagatgtttcacggcaaaccaa
aatgtcagggaaacctgctgtggacaggttattattatttcagattccgatgacgatgaa
gatgaggaaagaattctgggtttgaagaaacaaatgagagaggtcaaagcatgcattgag
aaagaatgtccagagcaacatacttcaatagctaacacaaatgtggaacagaaggtatta
ataaaggaagaaaatccagtgtcccttttggagtttgaggaatctgattctcagtttttt
gagtttgagactccatgtgaagtgttttcagtttggcatgatcagaaaccagacaagaat
tcagctcaagagaatgaaaaaaatccatgctcgactcatgtgggtgatagtgcaaatgat
ttgggttatgagacagattatgtgcctgaagaggtcattaaaaaagtagcagagaacttt
gaagagcgcacaaaaccacgtagtagtagtacttctgttgaggaattttgtgaaattgaa
gtaaaaaaacccaagagaagacggtatgaaaaacctatagctgaagatcctctaaggcct
tcttcatcttctgttaaaaatgaggaccagtctgatattcttaacaagggaaatctgagt
aaaaatgatgttaaaggtgtagacacaagatctacagttcccagttcaagtgttcagaga
aacactgtggtttccccaaagaagtctcttccaaagcctcgcatgtattccaaacctgtc
aggaaagttccagtggttaaagcttctaagaaatcccattcagataccaagaaagggcag
agtaaaagctcccattacataagttgtagaacaactcctgctattgtgccgccaaagaaa
tttcgccagtgtcccgaaccaacttcaacggttgagaaacttggcctgaaaaaggctcct
cgtagggcatttgaattgtcccagcgatctttagagtgtatagttcagctacgtgaccat
ggcaaaactgttggagtagtggatacccggaaaaagacgaagttaatttctcctcagact
ctctctgtcagaaataataagaaactgctgacgagtcaagaccttcagttgcaaaggcag
atgagatccaaatcacaacaaaacagacaacgttttgattgtcgaagtacagatagaact
cgagcagggccacgtgctgcacagagctctgctgtgccagaatcaagtaagtcagattac
agtcatggaggagccgaggtgactgctaacaataagggaaaacagttactaacatgtcag
tcttctgaaacagaacccgtgaaagcaaaccagtgtaatcctgtcatagtaaatggaaga
atagcaacaaatgaagtcattgttcctacctcagaggacctattagacagaggtgaccta
acagttcatcatttagaggtggcgactttgaaagagggagagcctcaattcagcagtgac
atagaggaagatgatatattcttaacacagcgtgaccctgaagacatggatttatgttca
caaatcgagagagagaatgataaactcattgaagtcattcatggaaaagatacagtgcag
ggagaggaagaatgtgtgagtcagcctcagttggaatctttgagtagcacaaaatgtaag
tacaaagattgtgttgaaactctgaaaaacccaggtgagtactgctcaaaacactcaaaa
actaaagccacagatgaagatgtattccgtaaacctggcttgcctctgtctgcatcaaaa
cgttcgagaccttccacgaccaaggtttttagttcaagcagtacttcacggattgctggt
ctctccaagtctttggaaagtaccgcagccctcccatcatctctgaaaaataagtcaagt
ggggcacagtctgttcttaaaggaccacagccaccccttacggtgtctctgaagccagtg
gctgaagtgaaaggtctgtgcaatgttttccctgctcagactccaaataactccaacagg
caagttctgagagttccatttggggaaagcagaccttttttgacttcctctccagtaaac
attctcacgtcgtcacagtccatctctgatacttttgtaaaagaggtcttgaaatggaga
tacgagatgtttgtgaactttgatcagtgtgggcccccgtcgagtctgtgtcagtccatc
gaaagacgggtgcctatcaggtttcaagactgtggagattattttaatgtgtttttccct
ttgatggtcctgaatacttttgaaacagtggcacaggaatggatcagctctccaaacaaa
gagaaattccatcagttacatttacgaaaatttcctggtgattataaaaaatactgggag
tttgtggtttatcttgaggaatgtgagctagctaaacagcttcatccaagggaaaatgat
ttggtgtttttggttcctgaaagactcaatgaggagaagaaagatttagagtggagtcac
ctggaggatgcctgtgaatattattgtggctatgttcataaattccgccgtacttcagtc
atgcataatgggaaatttgagtgttcggtttccatccagactcaagataatttaccagtc
aatttaaatgaactcgtgaaatgctttgtaatcagctctctggtgactacacaaaggaag
ttgaaagccatgtctttgctgagtggtcggaaccaactggccagagccattctgaatcca
aaccccatggacttctgtacaaaagatttaccaactgcaacatctgagagaattgttgcc
tacttaaaagatttcaatgaagaccagaagaaagcgatagaaactgcatgtgccatggtg
aaacactccccatcagttgccaagatctgtctgattcatggaccacctggaacaggaaaa
tcaaaaaccattgttggcatcctgtaccgcctgctgacagagaaccagaggagggggtat
tcagatgaaaactccaacgccaaaatcaagcaaaaccgtgtcctcgtatgtgctccttcc
aatgcagctgttgatgaacttatgaaaaaaattatccttgaattcaaagaaaagtgtaaa
gacaagaagaatcctatgggaaactgtggagatataaatttagtacgtctaggtccagaa
aagtctattaataatgaggtcctgaaattcagtttggacagtcaagttaaccacagaatg
aaaaaagacttaccgtctcatgttcaggagatgcacaaaagaaaggaatttcttgatcgt
caacttgatgaactttcccgccagcgtgctttatgccgaggtggaagggaatcgcagagg
caagaattagatggaaaaattgccagagtttcaaaagaaaggcaggagcttgcttctaaa
attaaagaggttcaaggacgcccacagaagacacagagcatcatcatcttagagtcacac
atcatttgctgcacgctgagcacgagtggtggcttgctgctcgaggctgctttccgtggg
caaggaggcgtccccttcagctgtgtcatcgttgatgaggctggacagtcttgtgaagtt
gaaactcttactccgctcatccatcgttgcaacaagcttgtcctcgtaggagaccctaag
cagctccctcccacagtcatttccgtgaaggcacaggactacggctatgaccagtcgatg
atggcccgcttccacaagctcctggaggagagtgtggagcacaacatgattggcaggctg
cccgtcttacagctcaccatccagtacaggatgcacccggacatatgcctctttccttct
agttatatttatgatggaatcttgagaacaaatagagggacagagaccagtcggtgctca
tctgactggccatttcaaccctacctcgtgtttgatgttggagatggcttagaaagacgg
gataatgactcatatgtaaatgttcaagagataaaactggtaatggaactaattaaactt
attaaagacaaacgaagggacgttactttccgaaacattggcataataacccattacaag
gctcagaagacaatgattcagaaggatttggacaaagagtttgatagaaaaggggcagca
gaagtcgataccgtggatgccttccaggggcgtcagaaagactgtgttattgttacatgc
gtcagagcaaatgccacacaaggctcaattggatttctggcaagtttgcagagattgaat
gtcaccatcacacgagccaagtacagcctcttcatcctcggacacttgagaaccctagtg
gaaaatagacattggtatcacctgattcaagatgcacagaaacgtggcgccattattaag
acttgtgacaagaactacagacacgatgcaatgaagatcctgaagctcaaaccattgctt
caaaggagccttactcaccctcctgctgtcgctccagaggcatccagaccccagggtggc
ctacccagcagcaagcaagatggtgaactcagcaagacatcttttgcttcttccctatac
cactcaccctctgactccaaagaagccacagtcactgaggctgcaaaggatcctgaaagg
ccacccaatcaggactggcttcgggacccaagactgctgcggaggatgggcttggccttg
gatgcccaaggaataagcctcagggagccgcagcccttgagcccccagcattccggagca
gcgcctcctttgggcgccccaggctgccctggaagtccccaggagccaggcagcatcagg
cagcagggagtcaccctgaacaaccacacgcctcacatgcagtgtgactctccagttgct
agtactgacacttccacaagcaaaaagaagtgtgaccaggaagagggggtgctcagccac
aggagagaaaccaggtccttgagtgtaggggatcaggagtggtgggctagctcccacgca
aagaggaactcagactgggatgagagggtcctggaggaggacagctgctcaaagaagaga
cgggttttatag
DBGET
integrated database retrieval system
