Bison bison bison (American bison): 105000878 Help Entry 105000878         CDS       T08726                                  Symbol ABL1 Name (RefSeq) tyrosine-protein kinase ABL1   KO K06619   abelson tyrosine-protein kinase 1 [EC:2.7.10.2] Organism bbis  Bison bison bison (American bison) Pathway bbis04012   ErbB signaling pathway bbis04014   Ras signaling pathway bbis04110   Cell cycle bbis04360   Axon guidance bbis04722   Neurotrophin signaling pathway bbis05200   Pathways in cancer bbis05206   MicroRNAs in cancer bbis05208   Chemical carcinogenesis - reactive oxygen species bbis05220   Chronic myeloid leukemia bbis05416   Viral myocarditis Brite KEGG Orthology (KO) [BR:bbis00001]  09130 Environmental Information Processing   09132 Signal transduction    04012 ErbB signaling pathway     105000878 (ABL1)    04014 Ras signaling pathway     105000878 (ABL1)  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     105000878 (ABL1)  09150 Organismal Systems   09156 Nervous system    04722 Neurotrophin signaling pathway     105000878 (ABL1)   09158 Development and regeneration    04360 Axon guidance     105000878 (ABL1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105000878 (ABL1)    05206 MicroRNAs in cancer     105000878 (ABL1)    05208 Chemical carcinogenesis - reactive oxygen species     105000878 (ABL1)   09162 Cancer: specific types    05220 Chronic myeloid leukemia     105000878 (ABL1)   09166 Cardiovascular disease    05416 Viral myocarditis     105000878 (ABL1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:bbis01001]     105000878 (ABL1) Enzymes [BR:bbis01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      105000878 (ABL1) Protein kinases [BR:bbis01001]  Non-receptor tyrosine kinases   ABL family    105000878 (ABL1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase F_actin_bind SH2 SH3_1 SH3_2 SH3_9 Haspin_kinase Kinase-like SH3_6 Motif Other DBs NCBI-GeneID:  105000878 NCBI-ProteinID:  XP_010855249 Ensembl:  ENSBBBG00000009543 UniProt:  A0A6P3IT28 LinkDB All DBs Position Unknown AA seq 1079 aa AA seqDB search MGQQPGKVLGDQRRPSLPALHFIKGAGKKEPSRHGGPHCNVFVEHEALQRPVASDFEPQG LSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCE AQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQR SISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRN KPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVE EFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRDCNRQEVNAVVLL YMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKF PIKWTAPESLAYNKFSIKSDIWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERP EGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKKGMRGVAGT LLQAPELPTKTRTSRRAAEHKDSPDMPETPHSKGPGETDPVDHEPAVSPLLPRKERGPPD GSLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGPPERKAASEEEGREI SNGALAPAPPDAVESAKSPKPSGGAGVPNGAFRESGGAGFRSPHLWKKSSTLTSSRLAAG EEESGSGASKRFLRSCSASCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPA LPRKRASENRSDQMTRGTVTPPPRLVKKTEEAADEVFKDAAEASPGSSPPSLTPKPIRRQ GAAAPPSSPPHKEEAGRPSAAGMPAEPEAAGEAGAGAKVKPAALAADAVNSDTAKSGQLG EGAKKPVLPSMPKPPASTKPAGTPTSPAPTPATLPSAPSALAGDQPSSTAFIPLISTRVS LRKTRQPPERIASGAITKGMVLDGTEALCLAISKNSEQMASHSAVLEAGKNLYTFCVSYV DSIQQMRNKFAFREAINKLENNLRELQICPATAGGGPAATQDFSKLLSSVKEISDIVQR NT seq 3240 nt NT seq  +upstreamnt  +downstreamnt atggggcagcagcctggaaaagttcttggggaccaaaggaggccaagtctgcctgccctg cactttatcaaaggagcaggcaagaaggagccatcaaggcatgggggtccacactgcaat gtttttgtggaacacgaagcccttcagaggccagtagcatctgacttcgagccccaaggt ctgagcgaagcagctcgttggaactctaaggaaaaccttcttgctggtcccagtgaaaat gaccccaacctttttgttgcactgtatgactttgtggccagtggggataacactttaagc ataactaaaggtgaaaagctccgggtcttaggctacaatcacaatggggagtggtgtgaa gcccaaaccaaaaatggccaaggctgggtcccaagcaactacatcacaccggtcaacagc ctggagaagcactcctggtaccacgggcctgtgtcccgcaacgccgccgagtaccttctg agcagcgggatcaacggcagcttcttggttcgggagagcgagagtagtcctgggcagagg tccatctcactgagatacgaaggaagggtgtaccactaccgcatcaacactgcttctgat ggcaagctctacgtctcctccgagagccgcttcaacacgctggccgagctggtccatcac cactccactgtggccgacgggctcatcaccactctccactacccggcccccaagcgcaac aagcccaccgtctacggcgtgtcccccaactacgacaagtgggagatggagcgcacggac atcaccatgaagcacaagctggggggtggccagtacggggaggtgtacgaaggcgtgtgg aagaaatacagcctgacggtggccgtgaagaccctgaaggaggataccatggaggtggag gagttcttgaaagaggctgcagtaatgaaagagatcaagcaccccaacttagtacagtta ctcggggtctgcacccgggagcccccattctacataatcactgagttcatgacctatggg aacctgctggactacctgagggactgtaaccggcaggaggtgaacgccgtggtgctgctg tacatggccacgcagatctcgtccgccatggagtacctggagaagaaaaacttcatccac agagatcttgctgcccgaaactgcctggtaggggaaaaccacttggtgaaggtggctgat tttggcctgagcaggctgatgacaggggacacctacacagcccacgccggggccaagttc cccatcaagtggacggcgcccgagagcctggcctacaacaagttctccatcaagtcggac atctgggcatttggagtgttgctttgggaaattgctacctatggcatgtcaccttaccca ggaattgacctgtcccaggtgtatgagctgttggagaaagactaccgcatggagcgcccg gaaggctgcccagagaaggtctacgaactcatgcgagcatgttggcagtggaatccctcc gaccggccctccttcgctgagatccaccaagcctttgaaacgatgttccaggaatccagc atatcagacgaagtggaaaaggagttggggaagaaaggcatgcgaggggttgcaggtacc ctgctgcaggccccagaactgcccaccaagacgagaacctccaggagagctgctgagcac aaagacagccccgacatgcccgagacaccccactccaagggcccaggagagactgatcct gtggaccacgaacccgctgtatctccactgctccctcgaaaagaacggggtcctccggat ggcagcctcaatgaggatgagcgcctgcttcccaaagacaagaagaccaacctgttcagc gccttgatcaagaagaagaagaaaaccgccccaacccctcccaaacgcagcagctccttc cgggagatggatggcccgcccgagcggaaagcggccagcgaggaggaaggccgggaaatc agcaacggggcgctggcaccggcacccccggatgcagtggagtcggccaagtccccaaag cccagcggcggggctggggtccccaacggagccttccgggagtctgggggcgcgggcttc cggtcgccccacctgtggaaaaagtccagcactctgaccagcagccggctggctgccggt gaagaggagagcggcagcggcgccagcaagcgcttcctgaggtcctgctcggcctcctgc gtgccccacggcgccaaggacacagagtggcggtcagtcaccctgcctcgggacctgcag tccaccggcaggcagttcgactcgtccacctttggaggccacaaaagcgagaagccggcc ctgcctcgaaagcgggcaagcgagaacaggtctgaccagatgaccagaggcacggttacc ccgccgccccggctggtgaagaaaaccgaggaggccgccgacgaggtcttcaaggatgcg gctgaggccagcccaggctccagcccacccagcctgacgccaaaaccaattcggaggcag ggtgcggccgcacctccctccagccctccccacaaggaggaggccggcaggcccagtgcc gcagggatgcccgctgagccggaagcggccggggaggcaggcgccggggcaaaggtgaaa cctgcagctctggctgcggatgccgtaaacagcgacaccgccaagtctggccagctggga gagggcgccaagaagcccgtgctcccatccatgccaaagccgccggcatccaccaagccg gcggggaccccgaccagccccgcccccacccccgccaccttgccgtcagcaccctctgcc ctggcaggggaccagccgtcctccaccgccttcattccactcatatcgacccgcgtgtct cttcggaaaacccggcagcctcctgaacggatcgccagtggcgccatcaccaagggcatg gtgctggatggcacggaggccctgtgcctggccatctccaagaactcagagcagatggcc agccacagcgccgtgctcgaagccggcaaaaacctttacacattctgcgtgagctacgtg gactccatccagcaaatgaggaacaaatttgccttccgcgaggccatcaacaaactggag aacaacctccgggagctgcagatctgcccagcaacagcaggtggtggcccagcggccact caggacttcagcaaactcctcagctccgtgaaggagatcagcgacatcgtgcagaggtag

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