KEGG   Bison bison bison (American bison): 105003529
Entry
105003529         CDS       T08726                                 
Symbol
IRAK4
Name
(RefSeq) interleukin-1 receptor-associated kinase 4 isoform X1
  KO
K04733  interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
Organism
bbis  Bison bison bison (American bison)
Pathway
bbis04010  MAPK signaling pathway
bbis04064  NF-kappa B signaling pathway
bbis04620  Toll-like receptor signaling pathway
bbis04621  NOD-like receptor signaling pathway
bbis04722  Neurotrophin signaling pathway
bbis04936  Alcoholic liver disease
bbis05132  Salmonella infection
bbis05133  Pertussis
bbis05135  Yersinia infection
bbis05140  Leishmaniasis
bbis05142  Chagas disease
bbis05145  Toxoplasmosis
bbis05152  Tuberculosis
bbis05161  Hepatitis B
bbis05162  Measles
bbis05164  Influenza A
bbis05168  Herpes simplex virus 1 infection
bbis05169  Epstein-Barr virus infection
bbis05170  Human immunodeficiency virus 1 infection
bbis05171  Coronavirus disease - COVID-19
bbis05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:bbis00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105003529 (IRAK4)
   04064 NF-kappa B signaling pathway
    105003529 (IRAK4)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    105003529 (IRAK4)
   04621 NOD-like receptor signaling pathway
    105003529 (IRAK4)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    105003529 (IRAK4)
 09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    105003529 (IRAK4)
   05161 Hepatitis B
    105003529 (IRAK4)
   05171 Coronavirus disease - COVID-19
    105003529 (IRAK4)
   05164 Influenza A
    105003529 (IRAK4)
   05162 Measles
    105003529 (IRAK4)
   05168 Herpes simplex virus 1 infection
    105003529 (IRAK4)
   05169 Epstein-Barr virus infection
    105003529 (IRAK4)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    105003529 (IRAK4)
   05135 Yersinia infection
    105003529 (IRAK4)
   05133 Pertussis
    105003529 (IRAK4)
   05152 Tuberculosis
    105003529 (IRAK4)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    105003529 (IRAK4)
   05140 Leishmaniasis
    105003529 (IRAK4)
   05142 Chagas disease
    105003529 (IRAK4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105003529 (IRAK4)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    105003529 (IRAK4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:bbis01001]
    105003529 (IRAK4)
Enzymes [BR:bbis01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     105003529 (IRAK4)
Protein kinases [BR:bbis01001]
 Serine/threonine kinases: TKL group
  IRAK family
   105003529 (IRAK4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Pkinase_fungal Haspin_kinase Death
Other DBs
NCBI-GeneID: 105003529
NCBI-ProteinID: XP_010859047
Ensembl: ENSBBBG00000015724
UniProt: A0A6P3J5H4
LinkDB
Position
Unknown
AA seq 461 aa
MNKPITASTYVRCLSLGLIRKLSDFIDPQEGWKKLAVAIKKPSGDDRYNQFHIRRFEALL
QIGKSPTCELLFDWGTTNCTVGDLVDILVQNEFFAPASLLLPDAVPKNVNTLPSKVTVVA
VQQKPKPLCGKDKTSVISDENLEQNYVLPDSSSPENTSLEFSDTRFHSFSFFELKDVTNN
FDERPISVGGNKMGEGGFGVVYKGYVNNRTVAVKKLAAMVDISTEELKQQFDQEIKVMAK
CQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWNMRCKIAQGAANGL
SYLHENHHIHRDIKSANILLDEDFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPEA
LRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYVDKKMN
DIDSTSIETMYSVASQCLHEKKNKRPDIKKVQQLLEEMTGS
NT seq 1386 nt   +upstreamnt  +downstreamnt
atgaacaaacccataacagcatcaacatacgtgcgctgcctcagtcttggactaattaga
aagctgtccgattttattgatcctcaagaaggatggaagaagttagcagtcgctattaaa
aaaccatctggtgatgatagatacaatcagtttcacataaggagatttgaagcattactg
caaattggaaaaagccccacgtgtgagttactgtttgactggggcaccacaaattgcaca
gttggtgatcttgtggatattttggtccaaaatgagttttttgcccctgcaagtcttttg
ctaccagatgctgtacccaaaaatgttaatacactgccttctaaagtcactgtagtagca
gttcagcagaaaccgaagcccctctgtggcaaagacaagacatctgtgatatctgatgag
aatcttgaacaaaactatgtgctacctgactcctcaagtccagaaaatacaagtttagaa
tttagtgatacacgttttcacagtttttcattttttgaattgaaggatgtcacaaataac
tttgatgaacggcccatttctgttggtggtaacaaaatgggagaaggagggtttggagtt
gtgtataaaggctacgtgaacaacaggactgtagcagtgaagaagcttgcagcaatggtt
gacattagtactgaagaactgaaacaacaatttgatcaagaaataaaagtaatggcaaag
tgtcaacatgaaaacttagtagaattacttggtttctcaagtgatggagatgacctctgc
ttagtatatgtttacatgcccaatggttcattgctggacagactgtcttgcttggatggt
actcccccactctcttggaacatgagatgcaagattgcccagggtgcagctaatggcctc
agttatttacatgaaaaccatcatattcatagagatattaaaagtgcaaatatcttatta
gatgaagactttacagccaaaatatctgactttgggcttgcacgggcttctgagaagttt
gcccagacagtcatgactagcagaattgtgggaacaacagcttatatggcacctgaagct
ttgcgaggagaaattacacccaaatctgacatctacagctttggtgtggttttgctagaa
ataataactggacttccagctgtggatgaacaccgtgaacctcagttattgctagatatt
aaagaagaaattgaagatgaagaaaagacaattgaagattatgttgataagaagatgaat
gacattgattccacttccattgaaactatgtactctgttgccagtcagtgtctgcatgaa
aagaaaaataagagaccagacattaagaaggttcaacagctgctagaagaaatgacaggt
tcttaa

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