KEGG   Bison bison bison (American bison): 105004048
Entry
105004048         CDS       T08726                                 
Symbol
ACACA
Name
(RefSeq) LOW QUALITY PROTEIN: acetyl-CoA carboxylase 1
  KO
K11262  acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
Organism
bbis  Bison bison bison (American bison)
Pathway
bbis00061  Fatty acid biosynthesis
bbis00620  Pyruvate metabolism
bbis00640  Propanoate metabolism
bbis01100  Metabolic pathways
bbis01212  Fatty acid metabolism
bbis04152  AMPK signaling pathway
bbis04910  Insulin signaling pathway
bbis04922  Glucagon signaling pathway
bbis04936  Alcoholic liver disease
Module
bbis_M00082  Fatty acid biosynthesis, initiation
Brite
KEGG Orthology (KO) [BR:bbis00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    105004048 (ACACA)
   00640 Propanoate metabolism
    105004048 (ACACA)
  09103 Lipid metabolism
   00061 Fatty acid biosynthesis
    105004048 (ACACA)
  09110 Biosynthesis of other secondary metabolites
   00254 Aflatoxin biosynthesis
    105004048 (ACACA)
 09130 Environmental Information Processing
  09132 Signal transduction
   04152 AMPK signaling pathway
    105004048 (ACACA)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    105004048 (ACACA)
   04922 Glucagon signaling pathway
    105004048 (ACACA)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    105004048 (ACACA)
Enzymes [BR:bbis01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.3  Carboxy- and carbamoyltransferases
    2.1.3.15  acetyl-CoA carboxytransferase
     105004048 (ACACA)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.14  biotin carboxylase
     105004048 (ACACA)
  6.4  Forming carbon-carbon bonds
   6.4.1  Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
    6.4.1.2  acetyl-CoA carboxylase
     105004048 (ACACA)
SSDB
Motif
Pfam: ACC_central Carboxyl_trans CPSase_L_D2 ACCA_BT Biotin_carb_N Biotin_carb_C Biotin_lipoyl ATP-grasp Dala_Dala_lig_C ATP-grasp_3
Other DBs
NCBI-GeneID: 105004048
NCBI-ProteinID: XP_010859850
Ensembl: ENSBBBG00000014359
UniProt: A0A6P3J8V9
LinkDB
Position
Unknown
AA seq 2383 aa
MWWSTLMSILRASSFWKWISAQTIRIIRALRAHFEEAMDEPSSLAKPLELNQHSRFIIGS
VSEDNSEDEISNLVKLDLLEEKEGSLSPASVSSDTLSDLGISSLQDGLALHMRSSMSGLH
LVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEKVLIANNGIAAVKCMRSIRRWSYE
MFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELILDIAKRIPVQ
AVWAGWGHASENPKLPELLLKNGIAFMGPPSQAMWALGDKIASSIVAQTAGIPTLPWSGS
GLCVDWHENDFSKRILNVPQELYEKGYVKDVDDGLKAAEEVGYPVMIKASEGGGGKGIRK
VNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISLFGRDCSVQRR
HQKIIEEAPAAIATPAVFEHMEQCAVKLARMVGYVSAGTVEYLYSQDGSFYFLELNPRLQ
VEHPCTEMVADVNLPAAQLQIAMGIPLYRIKDIRMMYGVSPWGDAPIDFENSAHVPCPRG
HVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSW
GENREEAISNMVVALKELSIRGDFRTTVEYLIKLLETESFQLNRIDTGWLDRLIAEKVQA
ERPDTMLGVVCGALHVADVSLRNSISNFLHSLERGQVLSAHTLLNTVDVELIYEGVKYVL
KVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDRYRITIGNKTC
VFEKENDPSVLRSPSAGKLIQYIVEDGGHVFAGQCYAEIEVMKMVMTLTAAESGCIHYVK
RPGAALDPGCVIAKMQLDNPSKVQQAELHTGSLPRIQSTALRGEKLHRVFHYVLDNLVNV
MNGYCLPDPFFSSRVKDWVERLMKTLRDPSLPLLELQDIMTSVSGRIPPNVEKSIKKEMA
QYASNITSVLCQFPSQQIANILDSHAATLNRKSEREVFFMNTQSIVQLVQRYRSGIRGHM
KAVVMDLLRQYLRVETQFQNGHYDKCVFALREENKSDMNTVLNYIFSHAQVTRKNLLVTM
LIDQLCGRDPTLTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVESI
FLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYEL
NSVQHRQLKDNTCVVEFQFMLPTSHPNRGNIPTLNRMSFSSNLNHYGMTHVASVSDVLLD
NAFTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFCDSPPQSPTFPEAGHTSLYDEDKVPRD
EPIHILNVAIKTDCDIEDDSLAAMFREFTQQNKATLVEHGIRRLTFLVAQKDFRKQVNYE
VDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQLELNRMRNFDLTAIPCANHKMHL
YLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFEYLQNEGERLLLEAMDELEVAFNN
TNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAELKINIRLTPTG
KAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQAYGDKQGPLHGMLINTPYVTKDLL
QSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSSQAFLPPPPLPSDILTYTELVLDDQG
QLVHMNRLPGGNEIGMVAWKMTLKSPEYPDGRDIIVIGNDITYRIGSFGPQEDLLFLRAS
ELARAEGIPRIYVAANSGARIGLAEEIRHMFHVAWVDPEDPYKGYKYLYLTPQDYKRVSA
LNSVHCEHVEDEGESRYKITDIIGKEEGLGAENLRGSGMIAGESSLAYDEIITISLVTCR
AIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGREVYTSNNQLGGIQIMHNNGVTHS
TVCDDFEGVFTVLHWLSYMPKSVYSSVPLLNSKDPIDRVIEFVPTKAPYDPRWMLAGRPH
PTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGGIPVGVVAVETRTVELSIPADPAN
LDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNREGLPLMVFANWRGFSGGMKDMYDQVLKF
GAYIVDGLRECSQPVMVYIPPQAELRGGSWVVIDPTINPRHMEMYADRESRGSVLEPEGT
VEIKFRRKDLVKTMRRVDPVYIHLAERLGIPLLSGGKIKESESKIKLRKPFIPPLXHEVA
VQFADLHDTPGRMQEKGVINDILDWKTSRTFFYWRLRRLLLEDLVKKKIHSANPELTDGQ
IQAMLRRWFVEVEGTVKAYVWDNNKDLVEWLEKQLTEEDGVRSVIEENIKYISRDYVLKQ
IRSLVQANPEVAMDSIVHMTQHISPTQRAEVVRILSTMDSPST
NT seq 7152 nt   +upstreamnt  +downstreamnt
atgtggtggtccactctgatgtcaatcttgagggctagttctttttggaagtggatatct
gctcagacaataagaattataagagctctgagagctcattttgaagaagcaatggatgaa
ccttcttccttggccaaacctctggagctgaaccagcactcccgattcataattggctcc
gtgtctgaagataactcggaggatgagattagcaacctggtgaagctcgacctgctggag
gagaaggagggctctctgtcgccagcctcggtcagctcagacacgctctctgacttgggc
atctcgagcctccaggatggtctggccttacacatgagatccagcatgtctggcttgcac
ctagtcaagcaaggtcgagaccgaaagaaaatagactcacagcgagatttcactgtagcc
tctccagcagaatttgttactcgttttggtgggaataaagtgattgagaaggttctcatt
gccaacaatggcattgcagctgtgaaatgcatgagatccatccgccggtggtcttatgag
atgtttcgaaatgaacgtgcaatccgatttgttgtcatggtcacacctgaagacctgaaa
gccaatgcagaatacattaagatggcggatcactacgtgcccgtgccaggaggccccaac
aacaacaactatgcaaatgtggagttaattcttgacattgctaaaaggatccccgtgcaa
gcagtttgggctggctggggtcatgcttctgagaatcccaagctcccagaacttctcttg
aaaaatggcatcgccttcatgggtcctccaagccaagccatgtgggctctgggggataag
atcgcatcttccatagtggctcaaactgctggtatcccaactcttccatggagtggcagt
ggtctttgtgtggactggcacgaaaatgatttttcaaaacgaattttaaatgttcctcag
gaactatatgaaaaaggttatgtgaaggatgtggatgatgggctgaaggcagcggaggaa
gttggatatccagtaatgatcaaggcctcagaaggaggaggagggaagggaatcagaaaa
gtcaacaatgcagatgacttccctaacctcttcagacaggttcaagctgaagttcctggg
tctcctatctttgtcatgagactagccaaacagtctcgtcatctggaggtgcagatctta
gcagatcagtatggcaatgctatctctttgtttggtcgtgattgctctgtgcaacgcagg
catcagaagattattgaagaagctcctgctgctattgctactccagcagtatttgaacat
atggaacagtgtgcggtgaaacttgccaggatggttggttatgtgagtgcagggactgtg
gaatacctctacagccaggatggcagcttctactttctggaactgaaccctcggctacag
gtggagcacccctgtacagagatggtggctgatgtcaacctccctgctgcgcagctccag
attgccatggggatccctctgtacagaatcaaggatatccgaatgatgtacggggtctct
ccctggggcgatgctcccattgattttgaaaattcggctcacgttccttgcccaaggggc
catgttattgctgctcgtatcactagtgaaaatccagatgagggttttaagcccagctca
ggaacagttcaagagctgaattttcgcagcaataagaacgtttggggttatttcagtgtt
gctgctgcaggagggcttcatgaatttgctgattctcagtttggtcactgcttttcctgg
ggagaaaaccgagaggaagcaatttcaaacatggtggtggctttgaaggagctgtctatc
cggggcgacttccggaccacagtcgagtacctgatcaaactgctggagactgaaagcttt
cagttgaacagaattgacacgggctggctggacagactgatagcagaaaaagtacaggcg
gagcgacctgacaccatgctgggagttgtctgtggggctctccatgtggcagacgtgagc
ctgcggaatagcatctccaacttccttcactccttagagaggggtcaagtcctctctgct
catacccttctgaatacagtagatgttgaacttatctacgagggagtgaagtatgtactg
aaggtgactcgacagtccccgaactcctacgtggtgatcatgaacggctcgtgtgtggaa
gtagacgtgcatcgactgagcgacggtggactgctcttgtcctatgacggcagcagttac
accacgtacatgaaggaggaggtggatagatatcgcatcacaattggcaataaaacttgt
gtgtttgagaaggaaaatgacccttcggtgctgcgctcaccctctgctgggaagttgatc
cagtacattgtggaggatggaggccacgtgtttgctggccagtgctatgccgagatcgag
gtgatgaagatggtaatgaccttaacagccgcagagtccggctgtatccattacgtcaag
cggcctggagcagctcttgacccgggctgtgtaatagccaaaatgcaactggacaacccc
agcaaggtccagcaggctgagcttcacacaggcagtctgccacggatccagagcacagcg
ctcagaggcgagaagctccaccgagtgttccactatgtcctggataatctggtcaatgtg
atgaatggatactgccttccagatcctttctttagcagtagggtgaaagactgggttgaa
cggttgatgaagaccctcagagacccctccttgcctctcctagaattgcaggatatcatg
actagcgtctctggtcgtatcccgcccaacgtggaaaagtctatcaagaaggaaatggct
cagtatgccagcaacatcacatccgtgctctgtcagtttcccagccagcagattgccaac
atcctagacagccacgcagccacactgaaccggaaatctgaacgggaagtcttcttcatg
aacactcagagcatcgtccagctggtgcagaggtaccgcagtggcatccgaggacacatg
aaggctgtggtgatggacctgctgcggcagtacctgcgagtagagacacaattccagaac
ggccactatgacaagtgcgtgttcgccctccgggaggagaacaagagtgatatgaacact
gtgctgaactacatcttctctcacgctcaggtcaccaggaagaatcttctggtcaccatg
cttatcgatcagctgtgtggccgggaccccaccctcactgatgagctgctgaatatcctc
acggagctaactcaactcagcaagaccaccaacgcgaaggtggcactccgagcacgccag
gttcttattgcttcccatttgccatcctatgagcttcgccacaaccaagtcgagtctatc
ttcctatccgccattgacatgtatggacatcagttctgcatcgagaacctgcagaaactc
atcttgtccgaaacgtcgatttttgacgtcctaccaaacttcttctatcacagcaaccag
gtcgtgaggatggcagctctggaggtgtatgttcgaagggcttatatcgcctatgaactt
aatagcgtacaacaccggcagctgaaggacaacacctgcgtggtggaattccagttcatg
ctgcccacatcgcatccaaatagagggaacatccccacgctaaacagaatgtccttctcc
tccaacctcaaccactacggcatgactcacgtagccagtgtcagcgacgtgctgctggac
aacgcgttcactccgccgtgtcagcggatgggcgggatggtctcttttcggacctttgaa
gattttgtcaggatctttgatgaagtgatgggctgcttctgtgattccccaccccaaagc
ccgacattccctgaggcaggtcacacgtctctgtatgacgaagacaaggtccccagggat
gaaccaattcacattttgaatgtggctatcaaaacagactgtgacatcgaggatgacagt
ctagcagctatgttccgagagtttacccagcaaaacaaagctaccctggttgaacatggg
atccgacgccttactttcctggttgcacaaaaggatttcaggaaacaagtcaactatgaa
gtggatcagagatttcatagagaatttcctaaatttttcacgttccgagcaagggataag
tttgaggaagatcgtatctatcgtcacctggagcctgccctagctttccagttagagctg
aaccggatgagaaattttgaccttactgccatcccgtgtgccaatcacaagatgcacttg
tatcttggggcagccaaggtggaagtgggcacagaagtgacagactacaggttctttgtt
cgtgcaatcatcaggcattctgatctggtcaccaaggaagcttcctttgaatatctacaa
aatgaaggggagcggctcctcctggaagccatggatgagttggaagtcgcctttaacaat
acaaatgtccggactgactgcaaccacatcttcctcaactttgttcctacagtcatcatg
gacccatcgaagattgaggaatccgtgcggagcatggtgatgcgctatggaagtcggctg
tggaagctgcgtgtcctccaggcagaactgaaaatcaacattcgcctgacaccaactgga
aaagcaattcccatccgcctcttcctgacgaacgagtctggctattacttggacatcagc
ctgtacaaggaagtgactgattccaggacagcacagatcatgtttcaggcatatggagac
aaacagggaccattacatggaatgttaatcaacactccgtacgtgaccaaagacctgctt
caatccaagaggttccaggcacagtccttagggacaacatacatatatgacatcccagaa
atgtttcggcagtccctgatcaaactctgggaatctatgtcctcccaagcattccttcca
ccgccccctctgccttcagacatactgacgtacactgagctcgtgttggatgatcaaggt
caactggttcacatgaacaggcttccaggaggaaatgagattggcatggtagcttggaaa
atgacccttaaaagtccagaatatccagacggccgagatatcattgttattggcaatgac
attacttaccgaattgggtcctttggaccccaagaggatttgctgtttctcagagcttct
gagcttgccagggcagagggcatcccacgcatctatgtagcagccaacagtggagcaaga
attggactggcagaggaaattcgtcatatgtttcacgtggcctgggtagatcctgaggat
ccttacaagggatacaaatatttatatctgacccctcaagattacaagagagtcagtgct
ctcaactctgtccattgtgaacatgtggaagatgaaggagaatccaggtacaagatcact
gacattattgggaaggaagaaggacttggagcagagaaccttcgagggtctggaatgatt
gctggggaatcctcgttggcctacgacgagatcatcaccatcagcctggttacatgcagg
gccattgggattggggcttacctcgtccgactgggacagagaaccatccaggtcgaaaat
tctcacttaatcctgacaggagctggggccctcaacaaagtcctcgggagggaagtatac
acttccaacaaccagctggggggcatccagatcatgcacaacaatggggtgacgcacagc
accgtctgtgacgacttcgagggggtgttcaccgtcctgcactggctgtcctacatgccg
aagagtgtatacagttcagttcctctcctgaattccaaggatccaatagacagagtcatc
gagtttgtgcccacgaaggcgccgtatgaccctcggtggatgctggcaggccggcctcac
ccaacccagaaaggtcagtggttgagtggattttttgactatggctctttctcagagatc
atgcaaccgtgggcacagactgtggtggttggcagagccaggctaggaggaatacccgtg
ggagtagttgccgtagaaacccgaacagtggagctgagcatcccggctgatcctgcaaac
ctggattctgaagccaagattatccagcaggctggccaggtttggttcccagactccgcg
tttaagacgtatcaggccattaaggacttcaaccgtgaagggctgcctctgatggtcttt
gccaactggagaggcttctccggtgggatgaaagatatgtacgaccaggtgctgaagttc
ggcgcttacatcgtggacggcttacgggagtgctcgcagcccgtgatggtctacatcccg
cctcaggccgagctccgaggcggctcctgggtggtgattgaccccaccatcaacccgcgg
cacatggagatgtatgcggaccgcgagagcaggggatccgttctggagccggaaggaaca
gtcgaaatcaaattccgcagaaaggatctggtgaaaaccatgcgtcgggtggacccagtc
tacatccacttggctgagcgattgggtatacctttgctgtctggaggaaaaataaaagaa
agcgaaagtaaaataaaattgagaaaaccttttattccccctctttaacacgaggtggcc
gtgcagtttgcagacctgcacgacaccccgggccgcatgcaggagaagggggtcattaac
gacatcctggattggaagacttcgcgcaccttcttctactggcggctgaggcggctgctg
ctggaggacctggtcaagaagaaaatccacagtgccaaccccgagctgacagacgggcag
atccaggccatgctgaggcgctggtttgtggaggtggaggggaccgtgaaggcctatgtc
tgggacaacaacaaggatctggtggagtggctggagaaacagctcacagaggaagacggc
gtccgctcggtgattgaagagaacatcaagtacatcagcagagactacgtcctcaagcag
atccgcagcttggtccaggccaacccagaggtcgccatggattccatcgtccacatgacg
cagcacatctcgcccacccagcgagcagaagtcgttcggatcctctcgacgatggactcg
ccgtcaacgtag

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