Bifidobacterium breve DSM 20213 = JCM 1192: BBBR_0151
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Entry
BBBR_0151 CDS
T04525
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
bbrd
Bifidobacterium breve DSM 20213 = JCM 1192
Pathway
bbrd00290
Valine, leucine and isoleucine biosynthesis
bbrd00620
Pyruvate metabolism
bbrd01100
Metabolic pathways
bbrd01110
Biosynthesis of secondary metabolites
bbrd01210
2-Oxocarboxylic acid metabolism
bbrd01230
Biosynthesis of amino acids
Module
bbrd_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
bbrd00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
BBBR_0151
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
BBBR_0151
Enzymes [BR:
bbrd01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
BBBR_0151
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GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
CATIP_N
DUF4953
Motif
Other DBs
NCBI-ProteinID:
BAQ99189
UniProt:
D4BLX3
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Position
204592..206508
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AA seq
638 aa
AA seq
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MGQDQSSVFDLAAVAAASNGGNNDPLLPPARFIGDSQKPSRMPYNKYASYSEQIPFDYPE
RTWPGKRLQRAPRWCSVDLRDGNQALVNPMDSERKLRFWNLLVSMGFKEIEVGFPSASET
DFDFIRMLIERELIPDDVTIVVLTQCREHLIRRTYEALKGAKRAIVHFYNSVSVLQREVV
FKKNKEEIKKLATDAAELCKDLESEAKGIDLYYEYSPESFTGTEPEYAVEVCNAVIGVIK
PTPEHPMIINLPATVEMTTPNVFADEVEYVSTHLDDRDSVVLSLHPHNDEGMGVAATELA
VLAGADRVEGCLLGNGERTGNVDLVTLGLNWLTQGIDPQLDLSNVPEIRKTVEYCNQIKI
SERHPYAGNFVFTAFSGSHQDAIKKGLEARQVAAERAGADLDSFVWLVPYLPIDPKDIGR
TYEAIIRVNSQSGKGGMAYLLKTNHNLDLPKRLQIEFDKIVQNFADTTKKEVKDEDIWRL
FKDEYLPVEQSGMTAAGVVVGDTHDASLAPWGRLKLLKVSVSSGEDGSDTVLKARLLDRG
VNVGGEQPVEREVSGIGNGPIAAFLNAISNFGVDASIMDYVEHTMSVGTDAMAASYVECQ
VGEADDAQIVWGVGIDSSITTSALKAIISAINRSQRNR
NT seq
1917 nt
NT seq
+upstream
nt +downstream
nt
atgggtcaggatcaatcgtccgtgtttgatctcgcggccgtggccgcggcgtccaatggg
gggaacaacgacccgctgctgcctccggcacgattcatcggcgattcgcagaagcccagc
cgtatgccgtacaacaagtacgcctcatacagcgagcagatcccgtttgattacccggag
cgcacgtggccgggtaagcgactgcagcgcgcaccgcgctggtgctccgtcgatcttcgc
gacggcaaccaggccctcgtcaacccgatggattccgagcgcaagctgcgcttctggaac
ctgctcgtctccatgggattcaaggagatcgaggtgggcttcccgtccgcatccgaaacc
gatttcgacttcatccgcatgctcatcgagcgcgagctcatcccggacgatgtgactatc
gtggtgctcacccagtgccgcgagcacctcatccgccgcacctacgaggcgctgaagggc
gccaagcgcgccatcgtgcacttctacaactccgtgtccgtgctgcagcgcgaagtggtg
ttcaagaagaacaaggaagagatcaagaagctcgccaccgacgccgctgaactatgcaag
gacctcgaatccgaggccaagggcatcgacctgtactacgagtactcgccggaatccttc
accggaaccgagccggagtacgccgttgaggtgtgcaacgccgtgatcggcgtcatcaag
ccgactcccgagcatccgatgatcatcaatctgcccgccaccgtggaaatgaccacgccg
aacgtgttcgccgacgaagtggagtacgtctccacccacctcgacgaccgtgattccgtg
gtgctctccctccacccgcacaacgacgaaggcatgggcgtggccgccaccgagctggcc
gtgctggccggcgccgaccgcgtggaaggctgcctgctgggcaacggtgagcgcaccggc
aacgttgacctggtcacgctgggcctcaactggctcacccagggcatcgacccgcagctc
gacctgtccaacgtacctgagatccgcaagacggttgagtactgcaaccagatcaagatt
tccgagcgccatccgtacgccggcaacttcgtgttcaccgcgttctccggctcgcatcag
gacgccatcaagaagggtctcgaggcccgtcaggtggccgccgagcgcgctggcgccgat
ctcgacagcttcgtctggctcgtgccctacctgccgatcgacccgaaggacatcggtcgc
acctacgaggccatcatccgcgtcaactcgcagtccggcaagggcggcatggcatacctg
ctcaagaccaaccacaaccttgacctgccgaagcgcctgcagatcgaattcgacaagatc
gttcagaacttcgccgacaccaccaagaaggaagtcaaggacgaggacatctggcgcctg
ttcaaggatgagtacctgccggtcgaacagtccggcatgaccgccgccggcgtggttgtg
ggcgatacccacgacgcttcgcttgcgccttggggccgcctgaagctgctcaaggtgtcc
gtcagctccggtgaggacggttccgacaccgtgctcaaggctcgcctgctcgaccgcggc
gtgaacgttgggggcgagcagcccgtggagcgcgaggtgtccggcatcggcaacggtccg
atcgccgccttcctcaacgccatctccaacttcggcgtggacgcctcgattatggactat
gtggagcacaccatgtccgtgggtaccgacgccatggccgcctcctatgtggaatgccag
gtcggtgaggctgacgacgcgcagatcgtgtggggcgtgggcattgactcgtccattacc
accagcgcgctgaaggcgattatctccgccatcaaccgttcccagcgcaaccgctga
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