KEGG   Bubalus bubalis (water buffalo): 102392528
Entry
102392528         CDS       T05912                                 
Symbol
IGF1
Name
(RefSeq) insulin-like growth factor I isoform X6
  KO
K05459  insulin-like growth factor 1
Organism
bbub  Bubalus bubalis (water buffalo)
Pathway
bbub01521  EGFR tyrosine kinase inhibitor resistance
bbub01522  Endocrine resistance
bbub04010  MAPK signaling pathway
bbub04014  Ras signaling pathway
bbub04015  Rap1 signaling pathway
bbub04066  HIF-1 signaling pathway
bbub04068  FoxO signaling pathway
bbub04081  Hormone signaling
bbub04114  Oocyte meiosis
bbub04115  p53 signaling pathway
bbub04150  mTOR signaling pathway
bbub04151  PI3K-Akt signaling pathway
bbub04152  AMPK signaling pathway
bbub04211  Longevity regulating pathway
bbub04213  Longevity regulating pathway - multiple species
bbub04510  Focal adhesion
bbub04550  Signaling pathways regulating pluripotency of stem cells
bbub04730  Long-term depression
bbub04750  Inflammatory mediator regulation of TRP channels
bbub04913  Ovarian steroidogenesis
bbub04914  Progesterone-mediated oocyte maturation
bbub04935  Growth hormone synthesis, secretion and action
bbub04960  Aldosterone-regulated sodium reabsorption
bbub05200  Pathways in cancer
bbub05202  Transcriptional misregulation in cancer
bbub05205  Proteoglycans in cancer
bbub05214  Glioma
bbub05215  Prostate cancer
bbub05218  Melanoma
bbub05224  Breast cancer
bbub05410  Hypertrophic cardiomyopathy
bbub05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:bbub00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102392528 (IGF1)
   04014 Ras signaling pathway
    102392528 (IGF1)
   04015 Rap1 signaling pathway
    102392528 (IGF1)
   04066 HIF-1 signaling pathway
    102392528 (IGF1)
   04068 FoxO signaling pathway
    102392528 (IGF1)
   04151 PI3K-Akt signaling pathway
    102392528 (IGF1)
   04152 AMPK signaling pathway
    102392528 (IGF1)
   04150 mTOR signaling pathway
    102392528 (IGF1)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    102392528 (IGF1)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    102392528 (IGF1)
   04115 p53 signaling pathway
    102392528 (IGF1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    102392528 (IGF1)
   04550 Signaling pathways regulating pluripotency of stem cells
    102392528 (IGF1)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    102392528 (IGF1)
   04914 Progesterone-mediated oocyte maturation
    102392528 (IGF1)
   04935 Growth hormone synthesis, secretion and action
    102392528 (IGF1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    102392528 (IGF1)
  09156 Nervous system
   04730 Long-term depression
    102392528 (IGF1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102392528 (IGF1)
  09149 Aging
   04211 Longevity regulating pathway
    102392528 (IGF1)
   04213 Longevity regulating pathway - multiple species
    102392528 (IGF1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102392528 (IGF1)
   05202 Transcriptional misregulation in cancer
    102392528 (IGF1)
   05205 Proteoglycans in cancer
    102392528 (IGF1)
  09162 Cancer: specific types
   05214 Glioma
    102392528 (IGF1)
   05218 Melanoma
    102392528 (IGF1)
   05215 Prostate cancer
    102392528 (IGF1)
   05224 Breast cancer
    102392528 (IGF1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    102392528 (IGF1)
   05414 Dilated cardiomyopathy
    102392528 (IGF1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    102392528 (IGF1)
   01522 Endocrine resistance
    102392528 (IGF1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:bbub04052]
    102392528 (IGF1)
Cytokines and neuropeptides [BR:bbub04052]
 Cytokines
  Growth factors (RTK binding)
   102392528 (IGF1)
SSDB
Motif
Pfam: Insulin
Other DBs
NCBI-GeneID: 102392528
NCBI-ProteinID: XP_006058874
UniProt: D2IJT0
LinkDB
Position
4:53850024..53928105
AA seq 154 aa
MGKISSLPTQLFKCCFCDFLKQVKMPITSSSHLFYLALCLLAFTSSATAGPETLCGAELV
DALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSAR
SVRAQRHTDMPKAQKEVHLKNTSRGSAGNKNYRM
NT seq 465 nt   +upstreamnt  +downstreamnt
atgggaaaaatcagcagtcttccaacccaattatttaagtgctgcttttgtgatttcttg
aagcaggtgaagatgcccatcacgtcctcctcgcatctcttctatctggctctgtgcttg
ctcgccttcaccagctctgccacggcgggacctgagaccctctgcggggctgagttggtg
gatgctctccagttcgtgtgcggagacaggggcttttatttcaacaagcccacggggtac
ggctcgagcagtcggagggcgccccagacaggaatcgtggatgagtgctgcttccggagc
tgtgatctgaggaggctggagatgtactgcgcgcctctcaagcccgccaagtcggcccgc
tcagtccgtgcccagcgccacaccgacatgcccaaggctcagaaggaagtacatttgaag
aacacaagtagagggagtgcaggcaacaagaactacagaatgtag

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