KEGG   Bubalus bubalis (water buffalo): 102392559
Entry
102392559         CDS       T05912                                 
Symbol
RAC1
Name
(RefSeq) ras-related C3 botulinum toxin substrate 1 isoform X1
  KO
K04392  Ras-related C3 botulinum toxin substrate 1
Organism
bbub  Bubalus bubalis (water buffalo)
Pathway
bbub04010  MAPK signaling pathway
bbub04014  Ras signaling pathway
bbub04015  Rap1 signaling pathway
bbub04024  cAMP signaling pathway
bbub04062  Chemokine signaling pathway
bbub04071  Sphingolipid signaling pathway
bbub04145  Phagosome
bbub04148  Efferocytosis
bbub04151  PI3K-Akt signaling pathway
bbub04310  Wnt signaling pathway
bbub04360  Axon guidance
bbub04370  VEGF signaling pathway
bbub04380  Osteoclast differentiation
bbub04510  Focal adhesion
bbub04517  IgSF CAM signaling
bbub04520  Adherens junction
bbub04530  Tight junction
bbub04613  Neutrophil extracellular trap formation
bbub04620  Toll-like receptor signaling pathway
bbub04650  Natural killer cell mediated cytotoxicity
bbub04662  B cell receptor signaling pathway
bbub04664  Fc epsilon RI signaling pathway
bbub04666  Fc gamma R-mediated phagocytosis
bbub04670  Leukocyte transendothelial migration
bbub04722  Neurotrophin signaling pathway
bbub04810  Regulation of actin cytoskeleton
bbub04932  Non-alcoholic fatty liver disease
bbub04933  AGE-RAGE signaling pathway in diabetic complications
bbub04972  Pancreatic secretion
bbub05014  Amyotrophic lateral sclerosis
bbub05020  Prion disease
bbub05022  Pathways of neurodegeneration - multiple diseases
bbub05100  Bacterial invasion of epithelial cells
bbub05132  Salmonella infection
bbub05135  Yersinia infection
bbub05163  Human cytomegalovirus infection
bbub05167  Kaposi sarcoma-associated herpesvirus infection
bbub05169  Epstein-Barr virus infection
bbub05170  Human immunodeficiency virus 1 infection
bbub05200  Pathways in cancer
bbub05203  Viral carcinogenesis
bbub05205  Proteoglycans in cancer
bbub05208  Chemical carcinogenesis - reactive oxygen species
bbub05210  Colorectal cancer
bbub05211  Renal cell carcinoma
bbub05212  Pancreatic cancer
bbub05231  Choline metabolism in cancer
bbub05415  Diabetic cardiomyopathy
bbub05416  Viral myocarditis
bbub05417  Lipid and atherosclerosis
bbub05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:bbub00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102392559 (RAC1)
   04014 Ras signaling pathway
    102392559 (RAC1)
   04015 Rap1 signaling pathway
    102392559 (RAC1)
   04310 Wnt signaling pathway
    102392559 (RAC1)
   04370 VEGF signaling pathway
    102392559 (RAC1)
   04071 Sphingolipid signaling pathway
    102392559 (RAC1)
   04024 cAMP signaling pathway
    102392559 (RAC1)
   04151 PI3K-Akt signaling pathway
    102392559 (RAC1)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    102392559 (RAC1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    102392559 (RAC1)
   04148 Efferocytosis
    102392559 (RAC1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    102392559 (RAC1)
   04520 Adherens junction
    102392559 (RAC1)
   04530 Tight junction
    102392559 (RAC1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    102392559 (RAC1)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    102392559 (RAC1)
   04620 Toll-like receptor signaling pathway
    102392559 (RAC1)
   04650 Natural killer cell mediated cytotoxicity
    102392559 (RAC1)
   04662 B cell receptor signaling pathway
    102392559 (RAC1)
   04664 Fc epsilon RI signaling pathway
    102392559 (RAC1)
   04666 Fc gamma R-mediated phagocytosis
    102392559 (RAC1)
   04670 Leukocyte transendothelial migration
    102392559 (RAC1)
   04062 Chemokine signaling pathway
    102392559 (RAC1)
  09154 Digestive system
   04972 Pancreatic secretion
    102392559 (RAC1)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    102392559 (RAC1)
  09158 Development and regeneration
   04360 Axon guidance
    102392559 (RAC1)
   04380 Osteoclast differentiation
    102392559 (RAC1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102392559 (RAC1)
   05205 Proteoglycans in cancer
    102392559 (RAC1)
   05208 Chemical carcinogenesis - reactive oxygen species
    102392559 (RAC1)
   05203 Viral carcinogenesis
    102392559 (RAC1)
   05231 Choline metabolism in cancer
    102392559 (RAC1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    102392559 (RAC1)
   05212 Pancreatic cancer
    102392559 (RAC1)
   05211 Renal cell carcinoma
    102392559 (RAC1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    102392559 (RAC1)
   05163 Human cytomegalovirus infection
    102392559 (RAC1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102392559 (RAC1)
   05169 Epstein-Barr virus infection
    102392559 (RAC1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    102392559 (RAC1)
   05135 Yersinia infection
    102392559 (RAC1)
   05100 Bacterial invasion of epithelial cells
    102392559 (RAC1)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    102392559 (RAC1)
   05020 Prion disease
    102392559 (RAC1)
   05022 Pathways of neurodegeneration - multiple diseases
    102392559 (RAC1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102392559 (RAC1)
   05418 Fluid shear stress and atherosclerosis
    102392559 (RAC1)
   05415 Diabetic cardiomyopathy
    102392559 (RAC1)
   05416 Viral myocarditis
    102392559 (RAC1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    102392559 (RAC1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    102392559 (RAC1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:bbub04131]
    102392559 (RAC1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:bbub04147]
    102392559 (RAC1)
   04031 GTP-binding proteins [BR:bbub04031]
    102392559 (RAC1)
Membrane trafficking [BR:bbub04131]
 Exocytosis
  Small GTPases and associated proteins
   Rho GTPases
    102392559 (RAC1)
 Endocytosis
  Lipid raft mediated endocytosis
   Arf6-dependent endocytosis
    102392559 (RAC1)
  Macropinocytosis
   Ras GTPases
    102392559 (RAC1)
 Others
  NADPH oxidases (Nox) and associated proteins
   Nox associated proteins
    102392559 (RAC1)
Exosome [BR:bbub04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   102392559 (RAC1)
  Exosomal proteins of other body fluids (saliva and urine)
   102392559 (RAC1)
  Exosomal proteins of colorectal cancer cells
   102392559 (RAC1)
  Exosomal proteins of bladder cancer cells
   102392559 (RAC1)
GTP-binding proteins [BR:bbub04031]
 Small (monomeric) G-proteins
  Rho Family
   Rac/Cdc42 [OT]
    102392559 (RAC1)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU CagD
Other DBs
NCBI-GeneID: 102392559
NCBI-ProteinID: XP_045020245
LinkDB
Position
24:complement(3994810..4013724)
AA seq 192 aa
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG
QEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLR
DDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPP
PVKKRKRKCLLL
NT seq 579 nt   +upstreamnt  +downstreamnt
atgcaggccatcaagtgtgtggtggtgggagacggagctgtgggtaagacttgcctcctg
atcagttacactaccaatgcattccctggagaatatatccccactgtctttgacaactac
tctgccaatgtcatggtggatggaaaacccgtgaatctgggcttgtgggacacagccgga
caagaagattatgaccgattacgccccctgtcctacccgcagacagatgtattcttaatt
tgcttttctctcgtgagtcctgcatcatttgaaaatgttcgtgcaaagtggtacccggaa
gtgcgacaccactgtcccaacacacccatcattctggtggggacgaaacttgacctgagg
gacgataaagacacgatcgagaagctgaaggagaagaagctgacgcccatcacctacccg
cagggcttggccatggccaaggagatcggtgccgtcaaatacctggagtgctcggcgctc
acgcagcggggcctcaagacagtgtttgatgaggcgatccgggcggttctctgcccaccc
cccgtcaagaagcggaagaggaagtgcctgctcttgtga

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