Bubalus bubalis (water buffalo): 102393826 Help Entry 102393826         CDS       T05912                                  Symbol PKLR Name (RefSeq) pyruvate kinase PKLR isoform X1   KO K12406   pyruvate kinase isozymes R/L [EC:2.7.1.40] Organism bbub  Bubalus bubalis (water buffalo) Pathway bbub00010   Glycolysis / Gluconeogenesis bbub00620   Pyruvate metabolism bbub01100   Metabolic pathways bbub01200   Carbon metabolism bbub01230   Biosynthesis of amino acids bbub04910   Insulin signaling pathway bbub04930   Type II diabetes mellitus bbub04932   Non-alcoholic fatty liver disease bbub04950   Maturity onset diabetes of the young Module bbub_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate bbub_M00002   Glycolysis, core module involving three-carbon compounds Brite KEGG Orthology (KO) [BR:bbub00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     102393826 (PKLR)    00620 Pyruvate metabolism     102393826 (PKLR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     102393826 (PKLR)  09160 Human Diseases   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     102393826 (PKLR)    04950 Maturity onset diabetes of the young     102393826 (PKLR)    04932 Non-alcoholic fatty liver disease     102393826 (PKLR)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:bbub04147]     102393826 (PKLR) Enzymes [BR:bbub01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.40  pyruvate kinase      102393826 (PKLR) Exosome [BR:bbub04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    102393826 (PKLR) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK PK_C HpcH_HpaI IMPDH Neuregulin Motif Other DBs NCBI-GeneID:  102393826 NCBI-ProteinID:  XP_025143479 LinkDB All DBs Position 6:15407967..15417207 Genome browser AA seq 526 aa AA seqDB search MEQIPGDRQRQQLPAAMADTFLEHLCLLDIDSEPVIARSTSIIATIGPASRSVERLKEMI KAGMNIARLNFSHGSHEYHAKSIANIREAVESFANSPLSYRPVAIALDTKGPEIRTGILQ GDPASEVEIVKGSQVLVTVDPEFQTRGDANTVWVDYPNIVRVMPVGGRIYIDDGLISLVV KKIGPEGLETEVENGGVLGSRKGVNLPGTQVDLPGLSEQDVQDLRFGVEHGVDIVFVSFV RKASDVAAVRDALGPEGQGIKIVSKIENHEGVKKFDEILEVSDGIMVARGDLGIEIPAEK VFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGET AKGNFPVEAVKMQHAIAREAEAAVYHRQFFEELRRAAPLSRDPTEVTAIGAVEAAFKCCA GAIIVLTTTGRSAQLLSRYRPRATIIAITRSAQAARQAHLCRGVFPVLYREPPEDIWADD VDRRVQFGIDNGKLCGFLHSGDLVIVVTGWQPGSGHTNIMRVLSVT NT seq 1581 nt NT seq  +upstreamnt  +downstreamnt atggagcagatccccggagacaggcagcggcagcagctgccagccgctatggcagacacc ttcctggaacatctgtgcctgctggacatcgactctgagcctgtgatcgctcgcagtacc agcatcatcgccaccatcgggccggcatctcgctccgtggaacgtctcaaggagatgatc aaggccgggatgaacatcgcgagactcaacttctcccacggctcccacgagtaccacgct aagtccatcgctaacatccgggaggcggtggagagctttgcaaattctccgctcagctac cgacccgtggccatcgccctggacaccaagggaccagagatacgcactgggatcctgcaa ggggacccggcgtcagaagtggagatagtgaagggctcccaggtgctggtgaccgtggac ccagagttccagacgcgcggggacgcgaacaccgtgtgggtggactaccccaatatcgtc cgagtcatgccggtggggggccgcatctacattgacgacgggctcatctccctagtggtc aagaaaatcggtccagaagggctagagaccgaagtggagaacggcggtgtcctgggcagt cggaagggcgtgaacttgccaggcacccaggtggacctgcccgggctgtccgagcaagat gtccaggacctgcgcttcggggtggagcatggcgtggacatcgtctttgtctctttcgtg cggaaagccagcgacgtggctgccgtccgggatgctctggggccggaaggacagggcatc aagatcgttagcaaaatcgagaaccacgagggcgtaaagaagttcgatgaaatcctggag gtgagcgacggcattatggtggcacggggtgacctgggcattgagatcccggctgagaag gttttcctggctcagaagatgatgatcggccgttgcaacttggcgggaaagcccgttgtc tgtgctacacagatgctggagagcatgatcactaagccccggccaactcgggcagagacg agtgacgtggccaatgctgttctggatggggcagactgcatcatgctgtcaggggagact gccaaaggcaactttcctgtggaggctgtcaagatgcaacatgcgattgcccgggaggca gaggctgctgtgtaccaccggcagttcttcgaggagctacgccgggcagcaccgctgagc cgggaccccacggaggtcactgctattggtgctgtggaggctgccttcaagtgctgtgct ggcgccatcattgtgctgaccacaactggccgctcagcccagcttctgtcccggtaccga cctcgggcaacgatcattgccatcacccgctctgctcaggctgcccgccaggcccacctg tgccgaggagtcttccctgtgctctaccgtgaacctccagaggacatctgggccgacgat gtggaccgtcgggtccaatttggcatcgacaatggaaagctctgtggcttcctccattct ggggacctggtgattgtggtaacaggctggcaaccaggctccggccatacaaacatcatg cgggtgctgagcgtaacctga

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