Bubalus bubalis (water buffalo): 102396928
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Entry
102396928 CDS
T05912
Symbol
TOP2B
Name
(RefSeq) DNA topoisomerase 2-beta isoform X2
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
bbub
Bubalus bubalis (water buffalo)
Pathway
bbub01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
bbub00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
102396928 (TOP2B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
bbub03032
]
102396928 (TOP2B)
03036 Chromosome and associated proteins [BR:
bbub03036
]
102396928 (TOP2B)
Enzymes [BR:
bbub01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
102396928 (TOP2B)
DNA replication proteins [BR:
bbub03032
]
Eukaryotic type
DNA Topoisomerases
102396928 (TOP2B)
Chromosome and associated proteins [BR:
bbub03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
102396928 (TOP2B)
Centrosome formation proteins
Centriole proteins
102396928 (TOP2B)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
DUF7180
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
102396928
NCBI-ProteinID:
XP_025142495
LinkDB
All DBs
Position
1:complement(5443207..5540885)
Genome browser
AA seq
1612 aa
AA seq
DB search
MAKAGGGGAGAGGHGALTWVNNAAKKEESEIANKNDSSKKLSVERVYQKKTQLEHILLRP
DTYIGSVEPLTQLMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTCIKV
SIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGA
KLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQPDLSKFK
MEKLDRDIVALMTRRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLDETGVALK
VIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKKKNKA
GVSVKPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAASNCGI
VESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGDSAKS
LAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYDDAES
LKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKNKQEL
SFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPEDDA
AITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELILFS
NSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQALMMT
IVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSTLARLLFPAVDDNLLK
FLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLDGLDPQP
MLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPMLNGT
DKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLFDHMG
CLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKITIEN
RSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEEESQNQHDDSSSDSGTPSGPDFNYILN
MSLWSLTKEKVEELIKQRDAKGREVSDLKRKSPSDLWKEDLAAFVEELDKVEAQEREDVL
AGMAGKAIKGKVGKPKVKKLQLEETMPSPYGRRVVPEITAMKADASKKLLKKRKGDLDAT
AVKVDFDEEFSGAAIEGGEEALIPSAPVNKGPKPKREKKEPGTRVRKTPTSSGKPSAKKV
KKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEEDDADDDDDNN
DLEELKVKASPIANDGEEEFVPSDGLDKDEYTFSPGKSKAAPEKSSHDKKSQDFGTLFSF
PSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTEKVPSKTVAAKKGKPSLDTAPKPKRA
PKQKKVETVNSDSDSEFGVPKKTAPKGKGRGAKKRKASGSENEGDYNPGRKTSKPPSKKP
KKTSLDEDSDVDLFPSDLTTDPPSLPRTGRARKEVKYFADSDEEDVDFAMFN
NT seq
4839 nt
NT seq
+upstream
nt +downstream
nt
atggccaaggcgggcggcggcggcgcgggagccggcggccacggggcgctgacctgggtg
aacaatgctgcaaaaaaggaagagtcagaaattgcaaacaaaaatgattcttcaaagaag
ttgtctgtcgagagagtgtatcagaaaaagacacaactcgaacatattctgcttcgtcct
gatacgtacattgggtcagtggagccattgacacagctcatgtgggtatatgatgaagat
gtaggaatgaattgcagagaggttacctttgtgccgggtttatataagatctttgatgaa
atcttggttaatgcagctgataataaacagagggataagaacatgacctgtattaaagtt
tctattgatcctgaatctaacattataagcatttggaataatgggaaaggcattccagta
gtagaacacaaagtagagaaagtttatgttcctgcattaatttttggacagcttttaaca
tccagtaactatgacgatgatgagaaaaaagtaacaggtggtcgcaatggttatggtgca
aaactttgtaatattttcagtacaaagtttacagtagaaactgcttgcaaagaatacaaa
catagttttaagcagacatggatgaataatatgatgaagacttctgaagccaaaattaaa
cattttgatggtgaagattacacatgtataacattccaaccagatctgtccaaatttaag
atggagaaacttgacagggatattgttgctctcatgaccagaagagcttatgatttggct
ggttcctgcaagggagtcaaggtcatgtttaatggaaagaaattgcctgtaaatggattt
cgcagttatgtagatctttatgtgaaagacaagttggatgaaacaggagtggccctaaaa
gttattcatgaacttgcaaatgaaagatgggacgtttgtctcacgttgagtgaaaaagga
ttccagcaaatcagctttgtaaatagcattgcaacaacaaaaggtggacggcatgtggat
tacgtagtagaccaagttgttggtaaactgattgaagtagttaagaaaaagaacaaagct
ggtgtgtcagtgaaaccatttcaagtaaaaaatcatatatgggtttttattaactgcctt
attgaaaatccaacttttgattctcaaacgaaggaaaacatgactttgcagcccaaaagt
tttggatccaaatgccaactatcagaaaaattttttaaagcagcctctaactgtggcatt
gtagaaagtatcctgaactgggtgaaatttaaggctcagacacagctgaacaagaagtgt
tcatcagtaaagtacagcaaaatcaaaggtattcccaaattggatgatgctaatgatgct
ggtggcaaacattccctggagtgcacactgatcctgacagaaggagactctgccaagtcc
ctggccgtgtctggattaggtgtaattgggagggacagatatggggtctttcccctcagg
ggaaagattcttaacgtgcgggaagcttctcacaaacagatcatggaaaatgcagaaata
aacaatattattaaaatagttggtctacaatataagaaaagttatgatgatgcagaatct
ctgaaaactttacgctatggaaagattatgattatgactgatcaggatcaagatggttct
cacataaaaggcctgctcattaacttcatccaccacaattggccgtcgcttttgaagcat
ggttttcttgaagagttcattacccctattgtaaaggctagcaaaaataagcaggaactt
tccttctacagtattcctgaatttgatgagtggaaaaaacatatagaaaaccagaaagcc
tggaaaataaaatactacaaagggttgggtaccagtacagctaaggaagccaaggaatat
tttgctgatatggaaaggcaccgtatcttatttagatacgctggtcctgaagatgatgct
gccattaccttggcattcagtaagaagaagatcgatgacagaaaagaatggttaacgaac
tttatggaagatcggagacagcgtaggttacatggcttaccagagcaattcttatatggt
acagcaaccaagcatttgacttataatgattttatcaacaaggaattgattctcttctca
aactcagacaatgaaagatctataccatctcttgttgatggttttaaaccaggtcaacga
aaagttttatttacctgtttcaagaggaatgataaacgcgaagtgaaagtcgcacagttg
gctgggtctgttgctgagatgtctgcttatcatcatggagaacaagcattgatgatgact
attgtgaacttggctcagaactttgtggggagcaacaacatcaacttgcttcagcctatt
ggtcagtttggaactcgacttcacgggggcaaagatgctgcaagccctcgttatattttc
acaatgttgagcactttagcaagactgctttttcctgctgtggatgacaacctgcttaaa
ttcctttatgatgataatcagcgtgtggagcctgagtggtatattcccataattcccatg
gttttaataaacggtgctgagggcattggcacaggatgggcttgtaagctgcccaactac
gatgccagagagattgtgaacaatgtcaggcgaatgctcgatggcctggatcctcagccc
atgcttccaaactacaaaaactttaaaggaacgatccaagaacttggtcaaaaccagtat
gcagtcagtggtgagatatttgtggtggatagaaacacggtggagattaccgagctccct
gtcagaacttggacacaggtatacaaagaacaggttttagaacctatgctaaatggaaca
gataaaacaccagcattaatttctgattataaagaatatcatactgatacaactgtgaaa
tttgtggtgaaaatgactgaagagaagctagcacaagcagaagctgctggattgcacaaa
gtttttaaacttcaaactactcttacttgtaattccatggtactctttgatcatatggga
tgtctgaagaagtatgaaactgtgcaagatattttgaaagaattctttgatttacgatta
agctattatggtttacgaaaggagtggcttgtaggaatgttgggagcagaatctactaag
cttaataatcaagcccgtttcattttagagaagatacaagggaaaatcactatagagaat
aggtcaaagaaagatttgattcaaatgttagtccagagaggttatgaatctgacccagtg
aaagcctggaaagaagcacaagaaaaggcagcagaagaggaagaatcacaaaaccagcat
gacgatagttcctctgattcaggaactccttcaggccctgattttaattatattttaaat
atgtctctatggtctcttactaaagaaaaagttgaagaactgattaaacagagagatgca
aaagggcgagaggtcagtgatcttaaaaggaaatctccttcagatctttggaaagaagat
ttagcagcttttgttgaagaactggataaagtggaagcgcaggaacgagaagacgttctg
gctgggatggccggaaaagcaatcaaggggaaggttggcaaacctaaggtgaagaagctt
cagctagaagagacgatgccctccccttatggcaggagagtggttcctgagatcactgcc
atgaaggcagatgccagcaagaagctgctgaagaagagaaagggtgatctggatgccaca
gcagtgaaagtggactttgatgaagagttcagtggagcagcaatagaaggtggagaagaa
gcattgatcccatcagctcctgtaaacaaaggtcccaaacccaaaagggagaaaaaagag
cctggtaccagagtgagaaaaacacctacgtcatctggtaaaccgagtgcaaagaaagta
aagaaacgaaatccttggtcagatgatgaatccaagtcagaaagtgacttggaagaaaca
gaacctgtggttattccaagagactctttacttaggagagcggctgctgaacggccaaag
tatacattcgatttctcagaagaggaggaggatgacgccgatgatgatgatgacaataat
gacttggaggagctgaaggtcaaagcatcacccatagcaaacgacggagaggaggagttt
gtcccctcagatggcctagataaagatgaatacacattctcaccaggcaaatcgaaagct
gctccagaaaagtcttcccacgacaagaagagtcaggattttgggactctcttctctttt
ccttcatactctcagaagtcagaagatgattcagctaaatttgacagtaatgaagaagat
tctgcttctgtattttcaccatcatttggtctgaagcaaacagaaaaagttccaagtaaa
acagtagctgctaaaaagggaaaaccatctttagatacagcccctaagcccaagagggcc
cccaaacagaagaaagtagagactgtgaactctgactcggattctgaattcggcgttcca
aagaaaacagcaccaaaaggtaaaggccgaggggcaaagaaaaggaaagcatctggctct
gaaaatgaaggtgattacaatcctggcaggaaaacctccaaaccaccaagcaagaagccg
aagaaaacctctttggatgaggactcagacgtggacctcttcccctcagacctcaccacc
gaccccccatcgctgccgcggactggccgggcaaggaaagaagtaaaatattttgcagac
tctgatgaggaagatgtcgattttgcaatgtttaattaa
DBGET
integrated database retrieval system
